Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
 Assessing community drug distributors’ participation in the river blindness program currently undergoing mass treatment: A case study of Kasese, Kitgum and Adjumani districts in Uganda
REFNo: SS2838ES

propose recommendations for improving/enhancing CDDs’ involvement and participation in RB programs for its future sustainability.,To assess communities’ perspectives about using CDDs during MDA. ,To establish whether the CDDs are needed to implement the MDA program and identify key stakeholders involved in the program at the community level.,To examine the facilitators and barriers to CDDS’ involvement and participation in the program. ,To explore the experiences and perspectives of the CDDs regarding their participation in the RB MDA program,To Identify the proportion of CDDs that have been selected and trained and those that have participated in the RB MDA program. ,The main objective of this study is to assess CDDs’ participation in the RB program activities in three selected districts currently undergoing mass treatment in western and northern Uganda to guide the review of existing programs or develop new ones altogether, to improve the CDDs’ future involvement and participation in MDA programs,
 Uganda 2024-07-09 18:26:45 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 Implementing oral (event-driven and daily) and long-acting Pre-exposure prophylaxis (PrEP) in mobile men in Sub-Saharan Africa: a phase 3b, open-label, hybrid type 2 implementation and effectiveness trial (MOBILE MEN)
REFNo: HS4366ES

Overall Objective
To assess effectiveness and implementation of long-acting cabotegravir (CAB-LA) and oral Truvada (both daily and event driven) through comparison of uptake, retention in care, coital coverage, and participant choice.
Uganda 2024-07-02 15:08:06 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Kiconco Prisca
ID: UNCST-2023-R005626
 HUMAN RESOURCE MANAGEMENT IN RELIGIOUS INSTITUTES IN UGANDA
REFNo: SS2769ES

To create awareness among the religious, basing on the fact that religious institutes have qualified, skilled and capable members who when distributed rightfully to different fields, there is possible production of effective results. ,To provide help to other religious institutes and other consecrated persons in and beyond Uganda as a resourceful material they can rely on as they manage human resource of the institute (s).,To establish the degree at which religious Institutes in Uganda are effectively managing their human resources for the benefits of the Institute and that of the Universal Church.,
 Uganda 2024-07-02 13:42:13 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Faustino Byanyima
ID: UNCST-2024-R004003
 Establishing the Effect of Financial Literacy on Financial Products Utilisation: a Case Study for Youth and Women Small Medium Enterprises in Southwestern Uganda.
REFNo: SS2660ES

Main Objective
The main objective of the study is to examine the effect of financial literacy on financial products utilisation among youth and women SMEs in Southwestern Uganda.

Specific Objectives
1. To determine the level of financial literacy among youth and women SMEs in Southwestern Uganda.
2. To identify the financial products used by youth and women SMEs in Southwestern Uganda.
3. To investigate the challenges and opportunities of financial product utilisation among youth and women SMEs in Southwestern Uganda.

 Uganda 2024-07-02 13:40:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Racheal Nalunkuma
ID: UNCST-2020-R014616
 Effect of the Facility-Based-Group-Model of the Differentiated Service Delivery on Stigma and Antiretroviral-Therapy-Adherence among Adolescents Living with Human-immunodeficiency-Virus in Central Uganda.
REFNo: HS4373ES

1. To evaluate the effect of the FBG model on ART Adherence among ALHIV in Central Uganda, comparing urban and rural HIV clinics from 2016 to 2023.
2. To determine the level of stigma among ALHIV under the FBG Model in Urban versus Rural HIV Clinics in Central Uganda.
3. To explore lived experiences towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.
4. To explore Peer leaders and Healthcare workers’ perception towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.

Uganda 2024-07-02 13:39:27 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Donald Kugonza Rugira
ID: UNCST-2021-R013291
 From Project to Program-based Extension Service Delivery: Assessment of the Impact of Interventions Implemented by the Centre for Sustainable Rural Livelihoods Program in Kamuli, Uganda
REFNo: A434ES

• Analyze the model/s and approaches used when delivering agricultural extension programs in Kamuli. • Identify farmers' perceptions of the effectiveness of the various agricultural technologies? used under the ISU-UP. • Identify clients' descriptions of effective and impactful agricultural and agricultural extension programs. • Capture and document clients’ success stories as a result of participating in the ISU-UP. • Capture donors' and program managers' perceptions of the agricultural and agricultural extension programs.
 Uganda 2024-07-02 13:38:11 2027-07-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Bernard Omech
ID: UNCST-2020-R014820
 Baseline characteristics and development of an integrated chronic disease care model for diabetes and hypertension management at primary healthcare facilities (ICDC)
REFNo: HS4285ES

To co-design an integrated chronic Diseases care model for management of hypertension and Diabetes mellitus through a participatory process to inform future intervention studies in Lango sub-region ,To examine the knowledge and practice of health care providers towards integration of chronic care for Hypertension and diabetes at selected PHC facilities in Lango sub-region ,To assess the patient’s perception of integration of chronic care for hypertension and diabetes mellitus among patients among patients attending selected primary health care facilities in Lango sub-region ,To determine baseline profiles (HBA1C levels, BP levels, QoL) of patients with hypertension and diabetes mellitus attending outpatient clinic at selected Primary health facilities in Lira City and District ,To evaluate baseline characteristics and develop a model of integrated chronic Disease care for management of hypertension and diabetes at primary health care in Lango Sub-region, Northern Uganda,
 Uganda 2024-07-02 12:56:36 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 INVENTORY, EFFECTIVENESS, AND SAFETY OF NOTIFIED NATURAL MEDICINES FOR THE TREATMENT OF DIABETES IN UGANDA: A PROSPECTIVE OBSERVATIONAL STUDY. A CONAT PROGRAM
REFNo: HS4356ES

The general objective is to create an inventory of NDA-notified natural or herbal medicines commonly used in the management of diabetes in adult patients in Uganda, and evaluate their preliminary effectiveness and safety Specific objectives are: 1. To establish the NDA-notified natural or herbal medicines commonly used in the management of DM among adults in Uganda 2. To determine the preliminary effectiveness of the NDA-notified natural or herbal medicines in lowering blood glucose levels when used in isolation or as complementary to conventional DM medicines 3. To assess the effect of the NDA-notified natural or herbal medicines on specific cardiometabolic characteristics of adult patients with DM in Uganda, when used in isolation or as complementary to conventional DM medicine 4. To determine the safety profile of the NDA-notified natural or herbal medicines when used in isolation or as complementary to conventional DM medicine in adult patients in Uganda
 Uganda 2024-07-02 12:54:13 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 ENHANCING PATIENT TRIAGE FOR NEUROSURGICAL CARE: A MIXED METHODS APPROACH
REFNo: HS4184ES

3. To design a patient triage model that accounts for criticality, resource availability, and healthcare costs.,2. To determine the key factors affecting patient triage decisions in neurosurgical care.,1. To assess the current patient triage system in neurosurgical care and identify its strengths and weaknesses.,The general objective of this research is to assess the current patient triage system in neurosurgical care, identifying its strengths and weaknesses in Uganda and Nigeria. ,
 Uganda 2024-07-02 12:52:48 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elliott Collins
ID: UNCST-2024-R005211
 Measuring the Impact of Group Loans and Digitized Ledgers on Savings Group Participants in Uganda
REFNo: SS2731ES

Measure the impact of savings group ledger digitization on savings group efficiency, savings behavior, and social cohesion.,Measure the impact of FAST loans on savings group participants’ access to financial services and livelihood outcomes.,
 USA 2024-07-02 12:50:51 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Mpendo
ID: UNCST-2024-R004147
 Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition
REFNo: HS4092ES

• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Number and characteristics of new HIV infections, including detection of resistance to CAB while on study. Secondary.
Secondary Objectives
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Incidence and severity of serious adverse events, Grade 3 and Grade 4 ISRs, and any clinical or laboratory adverse events leading to discontinuation of CAB while on study.

 Uganda 2024-07-02 12:49:10 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nandutu
ID:
EXPLORING THE DEVELOPMENT OF SCIENCE PROCESS SKILLS IN THE TEACHING OF MATHEMATICS EDUCATION IN TEACHER TRAINING INSTITUTIONS IN EASTERN UGANDA
REFNo: SS2566ES


1. To assess mathematics tutor’s understanding of science process skills in teacher training institutions
2. To find out science process skills developed by mathematics tutors in teacher training institutions
3. To examine the role of mathematics tutors in developing science process skills among teacher trainees in teacher training institutions

Uganda 2024-07-02 12:46:47 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 SEARCH2: A Randomized Control Trial of Telephonic Reminders for HPV Vaccination among Adolescent Girls in Kampala, Uganda
REFNo: HS3929ES


General Objective
To conduct a randomized control trial to assess the impact of text message and automated phone reminders on HPV vaccination.

Specific Objectives:
1.To assess the impact of text message and automated phone reminders on HPV vaccination.
Sub-objectives include:
1) To assess if text message and automated phone reminders were equally effective
2) To examine subgroup effects (girl: age, site, school status [in or out of school], grade, relationship with caregiver; caregiver: age, education, employment, income, marital status, distance to health facility, language), when possible depending on the degree of variability observed
3) to assess for possible additive or subtractive effects of receiving two series of message for families of girls who may have been in the intervention for both initiation and completion

Uganda 2024-07-02 12:45:18 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
 PARASTOP-Paracetamol with strong opioids
REFNo: HS4423ES

To explore whether placebo with strong opioids compared to paracetamol with strong opioids changes pain intenisty for different doses of opioids, different cancers and quality of lifeintensity,To establish whether placebo with strong opioids compared to paracetamol with strong opioids changes opioid related side-effects,changes in opioid requirements and global rating of improvement,To establish whether placebo with strong opioids compared to paracetamol together with strong opioids provides non-inferior analgesia for cancer related pain,To establish whether the analgesic efficacy of strong opioids after withdrawal of paracetamol is non-inferior compared the analgesic efficacy of strong opioids used together with paracetamol for cancer-related pain.,
 Uganda 2024-07-02 12:41:56 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
ANNY KATABAAZI  BWENGYE
ID:
GOVERNING BODIES’ FUNCTION AND PUBLIC UNIVERSITY FINANCING IN UGANDA: A CASE OF SELECTED UNIVERSITIES
REFNo: SS2708ES

1) To assess how the Adequacy and Allocative Efficiency function affects of public university financing.
2) To examine the relationship between the governing bodies’ policy function and pattern of public university financing.
3) To examine how the governing bodies’ financial function influences public university financing.
4) To determine the extent to which the governing bodies’ technical function influences public university financing.
5) To examine the challenges facing governing bodies in enhancing public university financing.
 Uganda 2024-07-02 12:40:29 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 Pediatric HIV Status Disclosure: Mental Health Outcomes, Barriers and Facilitators and Feasibility and Acceptability of Training Intervention in Improving Healthcare Workers’ Knowledge in Eastern Uganda.
REFNo: HS4017ES

1. To determine the prevalence of HIV status disclosure and association with mental health outcomes among CYALH in eastern Uganda. 2. To explore the experiences and coping mechanisms after HIV status disclosure after HIV status disclosure among young adolescents living with HIV in eastern Uganda 3. To explore the barriers and facilitators to HIV status disclosure to CYALH experienced by Healthcare workers (HCWs) in eastern Uganda . 4. To pilot and assess the feasibility and acceptability of a training intervention using WHO HIV status disclosure guidelines among HCWs to improve their knowledge about disclosure.
 Uganda 2024-07-02 12:35:50 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Kairania
ID: UNCST-2024-R016014
 Optimizing adoption and implementation of out-of-facility and clinic-based differentiated service delivery models for HIV treatment in Uganda: the OPTIONS study
REFNo: SS2776ES

Aim 1: Quantify individual-level and geographic variations in uptake of out-of-facility and clinic-based DSDM in 34 continuously surveilled communities. Approach: Using existing/secondary data from the Rakai Community Cohort Study.
Aim 2: Explore decision-making contexts and pathways to patient enrollment in out-of-facility and clinic-based differentiated HIV care models, as well as contextual and institutional determinants of DSDM adoption at clinic level.

Sub-Aim 2a: Identify modifiable conditions or mechanisms optimizing DSDM adoption in a heterogenous sample of HIV clinics.

Uganda 2024-07-02 12:33:52 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Nseka Kiyaga
ID:
The Role of Internal Audit on the Governance of Regulated Non-Deposit-Taking Microfinance Institutions in Uganda
REFNo: SS2778ES

iii) To construct an applied framework that may inform recommendations to institutionalize internal audits among regulated NDTMFIs in Uganda,ii) To examine the nexus within the academic literature on theories relating to corporate governance, internal audit, and microfinance,i) To investigate the role of internal audit on the governance of regulated NDTMFIs in Uganda,
 Uganda 2024-07-02 12:31:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2500™) in Detecting Intracranial Hemorrhage in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS4141ES

Use these findings to evaluate the InfraScanner 2500™\'s ability to accurately detect intracranial hemorrhages in darker-skinned populations within LMICs. ,Determine whether the InfraScanner 2500™ detects intracranial hemorrhage (ICH) with adequate precision relative to CT scans to be used as an effective triage tool to prioritize imaging and need for level of clinical monitoring in an African, LMIC population.,To demonstrate that the InfraScanner 2500™ is capable of detecting and ruling out intracranial hematomas at rates similar to CT scan in patients hospitalized at Mbarara Regional Referral Hospital who have sustained or are suspected to have sustained head trauma.,
 Uganda 2024-06-24 0:30:16 2027-06-24 Medical and Health Sciences Clinical Trial Non-degree Award
Kirabo Suubi
ID: UNCST-2023-R005659
 Making Social Protection Interventions Work for Marginalized Women in Kenya and Uganda: Understanding the state of research evidence, women’s preferences, and policymakers’ challenges in relation to Social Protection
REFNo: SS2785ES

To understand Ugandan and Kenyan policymakers’ experiences of designing and implementing SP programs and policies as well as their evidence needs related to SP.,To understand vulnerable Kenyan and Ugandan women’s perceptions of existing SP programs in their countries, and how they think SP initiatives can be best designed and delivered to them.,To synthesize findings of previous studies on the ingredients of effective SP interventions for women. ,
 Uganda 2024-06-24 0:28:26 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
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