Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Barnabas Atwiine
ID: UNCST-2022-R010629
 Assessing Implementation and Effectiveness of a Cash Incentive Family Support Intervention to Reduce Treatment Abandonment and Increase Survival among Children with Cancer in Sub-Saharan Africa
REFNo: HS3897ES

1. To assess the effectiveness of the intervention on end-of-treatment survival without evidence of disease.
2. To assess the proportion of eligible caregivers that access all planned mobile money instalments throughout the course of treatment.
3. To assess the cost-effectiveness of the intervention within the health system of participating
countries by WHO-CHOICE standards; defined as a cost less than three times the annual per
capita income per disability adjusted life year (DALY) averted.
4. To describe the views of stakeholders (policy makers, health providers and clients) on the acceptability and feasibility of the intervention.
Uganda 2024-05-07 11:43:52 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simran Prasad
ID:
Male reproductive skew, female codominance and mate choice, and inbreeding avoidance in wild vervet monkeys (Chlorocebus pygerythrus).
REFNo: NS801ES

The purpose of this project is to investigate the relationship between male dominance rank and mating and paternity success, degree of reproductive skew, female codominance and mate choice, and the direction of inbreeding avoidance in a population of vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo, Uganda.
Canada 2024-05-07 11:24:53 2027-05-07 Natural Sciences Non-Clinical Trial Degree Award
MUWANGUZI MOSES
ID: UNCST-2021-R013695
 Depression among pregnant teenagers receiving antenatal care from health facilities in Mbarara city, Southwestern Uganda
REFNo: HS3913ES

To determine the factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,To determine the prevalence of depression among pregnant teenagers in Mbarara city, southwestern Uganda. ,To determine the prevalence and factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,
 Uganda 2024-05-07 11:07:54 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel  Obakiro Baker
ID: UNCST-2019-R000065
 FORMULATION AND PRECLINICAL EVALUATION OF HERBAL PRODUCTS FOR MANAGEMENT OF DIABETES MELLITUS AND ITS COMORBIDITIES IN UGANDA
REFNo: HS4127ES

To analyze the phytochemical and pharmaceutical properties of the formulated herbal products,To assess the antidiabetic activity and toxicity of the formulated herbal products for the management of DM using in vitro and in vivo models,2. To formulate herbal products for management of DM ,1. To prioritize medicinal plants for formulation of herbal products for management of diabetes mellitus (DM),To develop standard herbal products for management of DM with proven preclinical evidence of efficacy and safety ,
 Uganda 2024-05-07 11:04:09 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Mbabazi Byakwaga
ID:
KIZINO DANCE-MUSICKING: NEGOTIATING ETHNIC IDENTITY AMONG BAKIGA IMMIGRANTS IN RUBIRIZI DISTRICT, WESTERN UGANDA
REFNo: SS2261ES

To examine how kizino dance-musicking is used to negotiate kikiga ethnic identity in Rubirizi District ,To explore the continuity and change in the nature and context of kizino dance-musicking among the Bakiga in Kabale and Rubirizi Districts,To examine the nature of the ethnic identity of the Bakiga in Kabale and Rubirizi Districts,To examine how Bakiga immigrants negotiate their ethnic identity in Rubirizi District,
 Uganda 2024-05-07 10:45:55 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
DORAH NAMPIJJA
ID: UNCST-2022-R009694
 Acute Rheumatic Fever Biomaker Project; Preventing Rheumatic Injury Biomarker Alliance: the Leducq PRIMA Network
REFNo: HS4091ES

iv. To design and validate a point of care diagnostic test for early ARF diagnosis,iii. To perform unbiased biomarker screens for ARF among children with ARF and to apply rigorous statistical analyses to identify biomarker(s) with high predictive power for ARF diagnosis ,ii. To conduct a case control study to understand the factors associated with ARF and disease progression among children aged 5-18 years,i. To create an Acute Rheumatic Fever registry and profile the phenotype among children with ARF aged 5-18 years,To identify accurate molecular biomarker(s) for ARF, and design a point of care diagnostic tool for early ARF diagnosis,
 Uganda 2024-05-02 12:45:10 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Magumba Nakagolo
ID:
The Influence of the Adoption of the E-tax System on Tax Compliance in Uganda.
REFNo: SS2552ES

To establish ways in which online tax systems can be maximally utilised to improve tax compliance in Uganda.,To establish the association between the adoption of eTax and taxpayer demographics, and how that association affects tax compliance in Uganda.,To establish the association between the adoption of eTax and tax administration efficiency, and how that association affects tax compliance in Uganda. ,To establish the relationship between the adoption of eTax and the different elements of tax compliance (registration, filing and payment) in Uganda.,To determine the influence of the adoption of the eTax system on tax compliance in Uganda. ,
 Uganda 2024-05-02 12:43:39 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Mathieu Chabry Eric
ID: UNCST-2024-R004404
 Toxoplasma in chimpanzees (Pilot study)
REFNo: NS789ES

This study is a pilot study which aims to look at the behavioral effects of the parasite Toxoplasma gondii in two populations of wild chimpanzees at the Budongo conservation field station. the project aims to understand correlations between infection and behaviors, to see if there are differences between infected and non infected individuals. The objectives of the research are the following:
- To see whether infection by the parasite toxoplasma gondii changes behavior of infected chimpaanzees by comparing infected and uninfected individuals (by comparing infected and non infected individuals)
- Establish infection status in a population of wild chimpanzees by collecting urine and check which individuals are infected and those which aren't (collecting urine non invasively)
- To see whether infection influences risky behaviors in wild chimpanzees (aggression towards higher ranking chimpanzees, foraging close to the borders of the territory)
- Determine if infection influences reaction to unfamiliar stimul (false fruits, remoted controlled animals maybe)
- Establish trends in behavior and compare infected and non-infected individuals
- Collect behavioral data in the purpose of establishing new studies possibilities
 Switzerland 2024-05-02 12:42:07 2027-05-02 Natural Sciences Non-Clinical Trial Degree Award
Charles Lwanga Tumuhe
ID:
Exploring perspectives of agroecology network organizations regarding their role in climate change adaptation in Uganda
REFNo: A409ES

To explore the understanding of agroecological initiatives made by the various network member organizations and their partners in their effort to help communities adapt to climate change.
To establish the perceived nature of the relationships and connections between agroecology as a movement and Climate Change adaptation

To establish the perceived benefits to network members from joint agroecological climate adaptation initiatives.

Uganda 2024-05-02 12:41:06 2027-05-02 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Kinera
ID: UNCST-2022-R009689
 POST TB LUNG DISEASE AMONG CHILDREN IN UGANDA, A CROSS SECTIONAL STUDY
REFNo: HS3961ES

3. To assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital.,2. To determine the correlation between clinical characteristics and lung function among children previously treated for PTB at Mulago National Referral Hospital.,1. To describe the clinical characteristics of PTLD among children previously treated for PTB at Mulago National Referral Hospital.,To describe the clinical characteristics of PTLD, assess the correlation between the clinical characteristics and lung function and to assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital. ,
 Uganda 2024-05-02 12:39:55 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 Simulation-based training for mesh inguinal hernia repair under local anaesthesia - a randomized trial
REFNo: HS4058ES

Assess the learning curve of mesh inguinal hernia repair for novice learners and how it is affected by simulation based training prior to supervised surgery on patients.
Sweden 2024-05-02 12:38:06 2027-05-02 Medical and Health Sciences Clinical Trial Degree Award
Daniel Zaake
ID: UNCST-2019-R000923
 Infertility in Uganda: The Burden, quality of Life, lived experiences of individuals Diagnosed with infertility and Availability of services for Diagnosis and treatment of infertility.
REFNo: HS3901ES

1. To determine the prevalence and determinants of infertility in Uganda.
2. To evaluate the quality of life among individuals with infertility seeking fertility treatment in Kawempe National Referal Hospital (KNRH) and St Francis Hospital Nsambya(SFHN) in Kampala
3. To explore the lived experiences of couples and individuals diagnosed with infertility at KNRH and SFHN in Kampala
4. To assess the availability of services for diagnosis and treatment of infertility in Uganda.
Uganda 2024-05-02 12:37:00 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Waiswa
ID:
The enablers and barriers to remote work for persons with disabilities in Greater Kampala Metropolitan Area, Uganda
REFNo: SS2394ES

To create a deeper understanding of the enablers and barriers to remote work, including impacts on employability, for PWDs in Greater Kampala Metropolitan Area, principally to inform practice and policy in the design of interventions for disability-inclusive employment in Uganda as the country fast-tracks the UN Convention on the Rights of People with Disabilities, Sustainable Development Goal 10, and Vision 2040.,
 Uganda 2024-05-02 12:20:40 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Sylvester Onzivua
ID:
A Postmortem Study to Explore the Pathological Basis of the Nodding Syndrome
REFNo: HS3048ES

(d) To compare the histological features in the various cases of the NS,c) To determine if there is any evidence of brain infection in NS. ,(b) To characterize the abnormal protein (tau) formation in the brain in NS. ,(a) To determine the main cellular processes occurring in the brain in the NS. ,Main Objective In the study postmortem brain samples will be used to explore the pathological basis of the NS. ,
 Uganda 2024-05-02 12:17:16 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHARLES BATUME
ID: UNCST-2021-R013411
 Insecticidal and repellent properties of essential oils from catnip (Nepeta cataria) against Aedes aegypti, Anopheles gambiae s.s. and culex quinquefasciatus.
REFNo: HS1717ES

To confirm residual activity and application intervals.,To determine the optimum application dosage(s) and the residual activity.,To determine the efficacy of repellent formulations at the selected application rates against the target vector species.,To establish dose–response relations and determine the ED50 and ED95 of the active ingredient for vector repulsion.,To determine effectiveness of catnip (Nepeta cataria) as mosquito repellent for Ae. aegypti, Anopheles gambiae s.s, and Culex quinquefasciatus.,
 Uganda 2024-05-02 12:11:13 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominic Bagenda K
ID: UNCST-2021-R013132
 Predictors of Menstrual Hygiene Management among Adolescent Girls in a Rural Resource-deprived Setting in Bukedea District, Uganda.
REFNo: SS1065ES

iv. To quantify the effect of parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,iii. To quantify the effect of socioeconomic predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,ii. To quantify the effect of personal predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,i. To determine the proportion of adolescents practicing adequate MHM in a rural resource-deprived setting in Bukedea District.,Quantify the effects of personal, socioeconomic and parental predictors on MHM practices among adolescent girls in a rural resource-deprived setting in Bukedea District.,
 Uganda 2024-05-02 12:08:52 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Testing efficacy and therapeutic potential of egg powder in prevention and management of moderate acute malnutrition: an intervention trial in drought-prone Karamoja, Northern Uganda
REFNo: HS2324ES

(i) Test the efficacy of powdered egg in the prevention of MAM and other related forms of malnutrition in children 6-59 months old. (ii) Assess the therapeutic potential of egg-based products in the management of MAM in the context of supplementary feeding.
Uganda 2024-05-02 12:04:25 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Korutaro
ID: UNCST-2019-R000618
 IMPAACT Early Career Investigator Award entitled, “Breastmilk Biomarkers of Inflammation, Immune Activation, and Human Milk Oligosaccharides (HMOs) in Women with vs. without Vertical Transmission During Breastfeeding
REFNo: HS4086ES

1. Determine the concentrations of total and various composition of human milk oligosaccharides (HMOs) (lacto-N-fucopentaose; lacto-N-neotetraose; lacto-N- tetraose; 2#-fucosyllactose; 3-fucosyllactose; and three #-sialyllactose); Immunoglobulin isotypes and subclasses (IgG1, IgG2b, IgG2c, and IgG3) in breastmilk of WWH at delivery (up to 5-days) and 4-6 weeks postpartum.

2. Assess the associations of HMO composition and immunoglobulin subclasses with breastmilk-associated HIV transmission.


 Uganda 2024-04-26 9:53:07 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
 Developing a guide for ethical review of AI-related research proposals involving human participants
REFNo: SS2558ES

I. To identify the gaps and challenges experienced by research ethics committees during review of AI-related health research projects
II. To examine the ethical considerations of health research involving human participants in AI research
III. To develop a guide for the review of AI-related research projects involving human participants.

 Uganda 2024-04-26 9:51:55 2027-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Sanya Edwin
ID: UNCST-2023-R006836
 Pathways to gestational diabetes screening and diagnosis: a pilot study Identifying health system barriers and facilitators to improve care in rural Uganda.
REFNo: HS4077ES

To investigate the availability of diagnostic services, guidelines, human resources, and financing for GDM care in Kagando HDSS,To explore the knowledge, attitudes, and practices of healthcare providers in detecting and managing GDM in Kagando HDSS,To explore experiences of women with current or previous GDM in Kagando HDSS about the diagnosis and management of GDM,To determine, using facility records, the burden of GDM in primary care facilities in the Kagando Health and Demographic Surveillance System (HDSS),The main objective of this study is to identify barriers and facilitators to the diagnosis of GDM in rural Uganda.,
 Uganda 2024-04-26 9:47:15 2027-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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