Isaac Ssewanyana
ID: UNCST-2020-R014336
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PERFORMANCE EVALUATION OF COVID-19 ANTIGEN RAPID DIAGNOSTIC TESTS
REFNo: HS1690ES
To determine the association of positive index test results with disease stage (days since symptom onset, e.g. acute, early, late), symptom severity and symptom severity.,To determine the diagnostic accuracy of SARS-CoV-2 Ag RDTs on a respiratory specimen (NP swab, OP swab, nasal swab, saliva), vs Cobas SARS-CoV-2 assay as performed in patients presenting with influenza-like illness.,
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Uganda |
2021-09-08 |
2024-09-08 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Pontiano Kaleebu
ID: UNCST-2021-R013577
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A clinical trial to assess the safety and immunogenicity of LNP-nCOV saRNA-02, a self-amplifying ribonucleic acid (saRNA) vaccine encoding the S glycoprotein of SARS-CoV-2, the causative agent of COVID-19, in SARS-CoV-2 seronegative and seropositive Uganda population
REFNo: HS1641ES
Primary Objective:
• To compare the safety and immune responses for SARS-CoV-2 seronegative and seropositive individuals from two immunisations with LNP-nCOV saRNA-02 administered IM 4 weeks apart at one dose level in 42 participants age 18-45 years.
Exploratory Objectives:
• To characterise the humoral and cellular immune responses to LNP-nCOV saRNA-02 administered at one dose given at 0 weeks and 4 weeks for individuals seronegative and seropositive for SARS-CoV-2 antibodies
• To characterise the profile of class and sub-class of antibody responses
• To characterize infection induced immune responses in participants with naturally acquired infection who are also exposed to the vaccine
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Uganda |
2021-09-08 |
2024-09-08 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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David Musoke
ID:
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Collaboration between Biomedical and Traditional Mental Health Service Providers in Wakiso District, Uganda
REFNo: HS1581ES
To explore how biomedical service providers and traditional healers can work together to improve access to mental health care in Wakiso district, Uganda.
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Uganda |
2021-09-08 |
2024-09-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Janet SEELEY
ID:
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Examining ethical issues, stakeholder engagement and acceptability of biobanking in Sub-Sahara Africa
REFNo: HS1645ES
General Objectives:
To explore perceptions, informed opinion and experiences of key stakeholders on approaches and value of community engagement in biobanking in LMIC; and if and how community approval should be obtained.
Specific Objectives:
1. To explore key stakeholders’ perceptions, informed opinions and underlying values around potential benefits of biobanks in SSA and important aspects of operationalising a biobank in LMICs.
2. To describe approaches that could be used to engage communities and stakeholders about biobanking.
3. To examine governance systems and structures that should be in place for a biobank to become operational, and ways in which community voices might be included in those systems
4. To determine initial key elements required to assume a community social license based on outputs of 1-3
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UK |
2021-09-08 |
2024-09-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Edward Mukiibi
ID:
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RESEARCH DATA MANAGEMENT PRACTICES IN SELECTED HEALTH INSTITUTES IN UGANDA
REFNo: HS1714ES
i) To describe the characteristics of research data created and held in selected Health Institutes in Uganda.
ii) To examine the research data management practices in selected Health Institutes in Uganda.
iii) To evaluate research data management readiness of selected Health Institutes in Uganda.
iv) To explain the challenges affecting adoption and uptake of RDM practices in selected Health Institutes in Uganda.
v) To propose interventions to improve RDM practices in selected Health Institutes in Uganda.
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Uganda |
2021-09-08 |
2024-09-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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