Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Dianah Ahumuza Ateenyi
ID:
The impact of tax incentives on the realisation of economic and social rights: A focus on tax holidays and the right to basic education in Uganda
REFNo: SS666ES

1. To examine the historical background and justification of tax incentives generally and tax holidays specifically especially in Uganda.
2. To explore the adequacy of the legal and policy framework on tax incentives, especially tax holidays in Uganda and how it impacts revenue for the realisation of ESRs, specifically the right to basic education;
3. To analyse the relationship between government revenue and basic education financing and how it the realisation of the right to basic education.
4. To recommend appropriate legal, policy and administrative reforms for the better management of tax incentives generally and tax holidays specifically for the realisation of Uganda’s international and domestic ESRs obligations, with specific emphasis on the right to basic education.

Uganda 2021-02-25 2024-02-25 Social Science and Humanities Degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory Viruses (INSIGHT Protocol No. 003 version 3.0, dated 27 August 2013); Flu003 PLUS AND Genomic Study: INSIGHT Protocol No. 004 version 2.0, dated 27 August 2013 -A substudy of qualifying INSIGHT studies
REFNo: HS1108ES

The objectives of this study for participants with confirmed influenza are to:

1. Characterize individuals who are hospitalized with influenza in terms of demographics, co-morbid conditions, prior influenza vaccination (seasonal, including 2009 H1N1) and pneumococcal vaccination, and use of antivirals, overall and according to influenza type, A or B, and influenza A subtype.

2. Estimate the percent who die and who develop a composite outcome, overall and according to the identified influenza type or subtype: death, a requirement for mechanical ventilation or admission to the intensive care unit (ICU), or prolonged hospitalization following enrollment (duration of hospitalization >28 days) at 60 days after enrollment.

3. Study risk factors, (e.g., patient and viral characteristics, geographic location, influenza type and subtype) for mortality and the composite outcome of death, a requirement for mechanical ventilation or admission to the ICU, or prolonged hospitalization following enrollment (duration of hospitalization >28 days).

4. Establish a repository of oropharyngeal, nasal and lower airway samples to determine a laboratory diagnosis; to molecularly characterize the virus, including subtype, antigenic and genetic analyses; to identify known signature mutations for antiviral drug resistance, mutational evolution, and additional re-assortment; and assess possible co-pathogens.

5. In a subset of patients requiring mechanical ventilation, to collect paired upper and lower airway samples to molecularly characterize the virus according to anatomic location, assess the potential emergence of antiviral resistance and assess possible co-pathogens.

6. Establish a repository of serum and plasma for future studies, including measurement of biomarkers that predict disease severity and measures of host response to infection with influenza virus.

7. Compare the characteristics and outcomes of patients infected with different influenza virus types and subtypes, including 2009 H1N1 virus, over time and by geographic region.

8. Identify and characterize other viral and bacterial pathogens, including coinfections.

The objectives of this study for participants with targeted non-influenza viral respiratory infections are to:

1. At enrollment, characterize individuals who are hospitalized with a targeted viral respiratory disease in terms of possible source of infection and mode of transmission, demographics and co-morbid conditions.

2. At 28 and 60 days of follow-up, estimate the percent who die, require admission to the ICU, have prolonged hospitalization, or recover.

3. Establish a repository of prospectively collected serum, plasma and respiratory tract specimens for future studies, including measurement of biomarkers that predict disease severity and measures of host immune response to infection.

Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Non-degree Award
Jane Frances Namatovu
ID: UNCST-2020-R014353
CONTINUING PROFESSIONAL DEVELOPMENT FOR PRIMARY CARE DOCTORS IN LOW RESOURCE SETTINGS: DEVELOPING A COMPETENCY-BASED FRAMEWORK
REFNo: HS1170ES

1.To determine the CPD training needs of primary care doctors working in public general hospitals (GHs) and health center IVs (HC IVs) of central Uganda
2.To explore the perceived barriers to and facilitators of CPD among primary care doctors working in public GHs and HC IVs of central Uganda
3.To explore the views of key stakeholders on CPD for doctors working in public GHs and HC IVs of central Uganda
4.To develop a competency-based CPD framework for primary care doctors working in public GHs and HC IVs of central Uganda
Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Targeting Domestic Animals and Tsetse Fly Vectors to Control Nagana and Accelerate Elimination of Acute Sleeping Sickness from Hot Spot Villages of Eastern Uganda
REFNo: A107ES

The main objective of this study will be to determine whether targeting hotspot villages would accelerate elimination of rHAT The specific objectives of this project will be to determine; i. If rHAT hotspot village-based interventions [two doses of diminazene aceturate 40 days apart at the beginning of the intervention and monthly RAP] will progressively reduce T. brucei s.l. reservoir in cattle and hence insidious rHAT transmission. ii. The drivers of insidious rHAT transmission in hotspot rHAT hotspot villages in Dokolo and Kaberamaido districts.
Uganda 2021-02-25 2024-02-25 Agricultural Sciences Non-degree Award
NOLBERT GUMISIRIZA KAGAMBIRWE
ID:
Investigating how the specialized and decentralized treatment healthcare models for all forms of epilepsy in Uganda fared in the covid-19 pandemic
REFNo: HS1156ES

1. To assess the government strategy of decentralized care and treatment for persons with all forms of epilepsy in Uganda, before COVID-19.

2. To assess the effects of the COVID-19 pandemic on access to epilepsy care in Uganda

3. To assess the socio-economic and mental health effects of the COVID-19 pandemic on persons with epilepsy in Uganda.

4. To generate ideas and strategies to improve the existing models for epilepsy care in Uganda∙

Uganda 2021-02-25 2024-02-25 Medical and Health Sciences Degree Award
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