Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Faith Nawagi
ID: UNCST-2021-R013751
AFREhealth-FAIMER Interprofessional Education Student Exchange Program Evaluation Plan.
REFNo: HS4461ES

The AFREhealth-FAIMER IPE program evaluation aims to assess the key process factors required for implementation of an IPE elective program, impact and the outcomes of the program at the student, faculty, institutional, and AFREhealth Network levels.,4. To document the key process factors of developing and implementing the AFREhealth-FAIMER IPE elective program. ,3. To identify the outcomes of the AFREhealth–FAIMER IPE elective program on the participating institutions and AFREhealth as an organization at large.,2. To evaluate the participating faculty, students, program managers, institutional leaders, and AFREhealth leaders’ perspectives on the AFREhealth-FAIMER IPE elective program curriculum. ,1. To establish the IPECP skills gained by the students participating in the AFREhealth-FAIMER IPE elective program. ,
Uganda 2024-07-17 12:04:18 2027-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anxious   Niwaha Jackson.
ID: UNCST-2023-R008010
Patho-physiologic and metabolic characterisation of Lean Diabetes in Uganda (LEAN-D study)
REFNo: HS4533ES

1. To establish the principal cause of hyperglycemia in lean SSA diabetes. (Hyperglycemia is high blood sugar)
2. To determine the association between biomarkers of beta cell function, and body composition and lean type 2 diabetes.
3. To establish if Persistent Organic Pollutants are present in sufficient levels in individuals with lean SSA diabetes to contribute to the process of developing diabetes.
4. To translate knowledge products into formats that are accessible and usable by key stake holders to enhance lean diabetes diagnosis, and inform policy and intervention strategies.

Uganda 2024-07-15 8:24:33 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Genetic, Biological and Psychosocial predictors of Incident and Persistent Internalizing Mental Disorders among Ugandan Children and Adolescents living with HIV: A Machine Learning Approach.
REFNo: HS4521ES

1. To build a machine learning model for prediction of prevalent, incident, and persistent cases of Internalizing Mental Disorders among Ugandan children and adolescents living with HIV.
2. To evaluate the performance of the machine learning model (developed in 1 above) based on each of genetic, biological, and psychosocial factors respectively.
3. To evaluate the performance of the machine learning model based on the combination all the three factor domains of genetic, biological, and psychosocial factors.

Uganda 2024-07-15 8:22:11 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Advancing Vaccine Development: Harnessing Multiple Antigenic Epitopes for Crimean-Congo Hemorrhagic Fever in Humans and Animals
REFNo: HS4493ES

Overall objective To develop and evaluate an adenovector CCHFV vaccine candidate. Sub-study general objectives i) To design the CCHFV immunogens and construct an adenovector CCHF vaccine candidate by conjugating the immunogens into the adenovector backbone. ii) To conduct preclinical studies of the CCHF vaccine in mice and non-human primates (animal models). iii) To translate knowledge products into formats that are accessible and usable by key stakeholders to enhance CCHF vaccine discovery and scale up.
Uganda 2024-07-15 8:16:36 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jolly  Kamugisha G.K.
ID: UNCST-2023-R005715
Evaluation of The Early Childhood Nutrition Programme In The Karamoja Region, Uganda. RefNo: JCRC-2024-78:
REFNo: HS4490ES

To assess ECD centre readiness to implement integrated early childhood nutrition interventions in order to inform programming that fosters early childhood development in the Karamoja regionTo determine the early childhood developmental status of children aged 0-24 months in the Karamoja region. To determine the contextual barriers and facilitators to implementation of comprehensive nutrition interventions in ECD centres and their catchment communities in the Karamoja region To determine the effect of comprehensive early childhood nutrition interventions on Early Childhood Developmental status among children aged 24-59 months in the Karamoja region
Uganda 2024-07-12 14:50:24 2027-07-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mamerito Nturanabo
ID: UNCST-2024-R004377
Social Equity Interventions and Maternal health outcomes in Bugiri District, Eastern Uganda
REFNo: SS2781ES

To establish the effect of legislation on the maternal Health in Bugiri District, Eastern Uganda,To establish the civic education effect on maternal health in Bugiri District, Eastern Uganda.,To establish Health provision effect on maternal health in Bugiri District, Eastern Uganda,To assess the relationship between social equity interventions and maternal health outcomes in Bugiri District, Eastern Uganda.,
Uganda 2024-07-10 13:41:35 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Shamirah Najjinda
ID:
Family support, entrepreneurial resources, resilience and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda
REFNo: SS2842ES

To determine the levels of understanding of entrepreneurial wellbeing by women entrepreneurs in Uganda.To establish the relationship between family support and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To examine the relationship between entrepreneurial resources and entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.To explore the influence of entrepreneurial resilience on the entrepreneurial wellbeing of women entrepreneurs in the hospitality and tourism industry of Uganda.
Uganda 2024-07-10 13:40:22 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Lucas Ampaire
ID:
DIGITIZED CBC RESULTS TRANSMISSION TO SHORTEN TURN AROUND TIME AT MBARARA REGIONAL REFERRAL HOSPITAL (dCRT STUDY)
REFNo: HS4264ES

To design a mobile app as an intervention to shorten delay for CBC results transmission from the Mbarara Regional referral hospital Laboratory to the requesting clinician,To determine the perceived contributing factors to CBC results delay at Mbarara regional referral Hospital,To establish the prevalence of CBC results delays at Mbarara regional referral Hospital:,
Uganda 2024-07-10 13:38:14 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patricia Nabwami Esther
ID:
Evaluating the Health Systems Preparedness for Ebola Virus Disease outbreak in Mubende and Kassanda Districts in Uganda
REFNo: SS2828ES

3. To establish the existing capacities for management of EVD outbreaks containment at the local health facilities. ,To determine the status of stock piling levels for Ebola Virus Disease in health facilities.,1. To establish the level of preparedness among health care workers’ for containment of Ebola Virus Disease.,To evaluate the preparedness levels of health system for Ebola outbreak response in Mubende and Kassanda Districts in Uganda. ,
Uganda 2024-07-10 13:37:12 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Ellen Forsman Larsson
ID:
“Have you been saved?” Ecstatic exorcism as therapeutic healing
REFNo: SS2494ES

This project focuses on the Balokole church, aiming to produce an ethnographic analysis of the movement. The purpose of this research is to understand how the movement interacts with global Christianity while simultaneously inflecting local practices. In particular, It will look at the types of worship undertaken in the church, and how they are experienced within the congregation. The members of this movement commonly experience so-called ‘deliverances’ - where congregants are exorcised and cleansed of demons and evil spirits. Those who undergo deliverances tell of its healing effects. The ultimate aim of the project is to understand what deliverance is, and what happens to a person when they undergo it. It will also explore the personal transformation that happens when a person is ‘born again’, to better understand the therapeutic effects which conversion, deliverance and other rituals can have.
Sweden 2024-07-10 13:35:12 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Kitonsa
ID:
Assessing the knowledge, perceptions, and uptake of HPV vaccine and evaluation of vaccine delivery strategies among non-school-going girls in southwestern Uganda
REFNo: HS4559ES

Quantitative study objectives 1. To assess knowledge, attitudes, and perceptions about the HPV vaccine among non-school going girls between 9 and 20 years. 2. To determine HPV uptake, willingness, and barriers to use HPV vaccines among nonschool going girls between 9 and 20 years. 3. To determine favourable vaccine delivery strategies for non-school going girls. Qualitative study objectives 1. To explore the willingness and acceptability of taking up an HPV vaccine among nonschool going girls between 9 and 20 years. 2. To explore the knowledge, attitudes, and perceptions about HPV vaccine among nonschool going girls, parents/care givers, and healthcare providers. 3. To describe the facilitators and barriers to the uptake of HPV vaccine among non-school going girls, parents/care givers, and healthcare providers.
Uganda 2024-07-10 13:31:20 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Solomon Nsumba
ID:
Intelligent wearable systems for detecting medication errors at CoRSU Rehabilitation Hospital
REFNo: SIR360ES

To design and implement a low-power, real-time wearable system that seamlessly integrates with existing medical equipment, facilitating continuous monitoring and detection of medication errors during surgical procedures.,To prototype a software system capable of providing real-time feedback to medical personnel and generating automated records based on detected medication errors, integrating insights from the developed computer vision models.,To develop advanced computer vision models tailored to accurately detect and classify drug delivery events and associated errors, leveraging insights from the curated dataset,To curate a comprehensive video/image dataset capturing diverse medical drug events and errors in real-time during surgical procedures.,Overall Goal is to develop machine learning models that can detect medical drug events and errors in real-time during surgery.,
Uganda 2024-07-10 13:29:17 2027-07-10 Engineering and Technology Non-Clinical Trial Degree Award
Kristen Little Marie
ID:
Exploring the Non-Hormonal and On-Demand Contraceptives Value Propositions: Perspectives from End Users, Private Sector Healthcare Providers, and Stakeholders in Kenya, Nigeria, and Uganda
REFNo: SS2745ES

: To understand the benefits, challenges, and preferences for the on-demand pill, including product naming and framing, and perspectives on a standalone vs. EC+ on-demand pill, among potential end-users. Sub-aims: 1.) To explore women’s perceptions regarding non-hormonal contraceptives (relative to hormonal options) and their stated preferences for product attributes including dosing schedule, side effects, and benefits; 2.) to describe women’s current use of emergency contraceptive pills, including routine, regular, or repeated use of ECPs, and these users’ perspectives on a potential on-demand pill product.,To understand motivators and barriers and support required for private healthcare providers (HCPs) to consider stocking/selling the LNG 1.5 on-demand/pericoital contraceptive pill. Sub-aim: To understand provider perspectives on the value of and barriers to a weekly, non-hormonal pill in the private sector.,Explore the acceptability of on-demand and non-hormonal contraceptives among private providers, user preferences for on-demand and weekly non-hormonal products among adult women, and key informants and market actors to inform clinical trial pathway decisions and product positioning,
USA 2024-07-10 13:28:15 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Mathuva
ID:
Transforming Social Ministries into Sustainable Social Enterprises by the Religious Sisters in the Catholic Church
REFNo: SS2158ES

The purpose of this study is to contribute to the body of knowledge on the work of Catholic sisters as they seek to transform their social ministries and charities into sustainable social enterprises.
Kenya 2024-07-10 13:25:42 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
Clinical Equivalence Validation of the ANC panel (professional use)
REFNo: HS4369ES

The primary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against the individual DetermineTM tests based on a) finger-stick samples and b) venous whole blood samples.
The secondary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against laboratory-based reference testing.
As a secondary objective, a user experience questionnaire will also be completed by each professional test user
UK 2024-07-10 13:24:19 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Marvin Kadigo
ID: UNCST-2024-R004323
Perspectives and preferences of both refugees and hosts on refugee local integration in Uganda
REFNo: SS2797ES

The main objective of the study is to comprehensively evaluate the perspectives and preferences of both refugee and host populations regarding the local integration of refugees within Uganda.To determine the average preference of both refugees and hosts (Ugandans) for the different integration scenarios
Uganda 2024-07-09 18:43:00 2027-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Harold OGWAL
ID: UNCST-2024-R005378
EFFECTS OF WETLAND SPATIO-TEMPORAL CHANGES ON WATER QUALITY AND SEDIMENTS, A CASE OF OKOLE WETLAND IN LIRA CITY.
REFNo: NS815ES

To explore the socio-ecological and economic drivers associated with wetland degradation within Lira City ,To examine the effect of wetland changes on the sediment concentration of the wetland systems within Lira City ,To evaluate the impacts of wetland degradation on the water quality of the identified wetland systems within Lira City,To conduct spatio-temporal analysis of wetland changes between 1999 and 2023 within Lira City,To study the effects of Okole wetland spatiotemporal changes on water quality and sediments within Lira city,
Uganda 2024-07-09 18:37:28 2027-07-09 Natural Sciences Non-Clinical Trial Degree Award
Nsobya  Samuel
ID: UNCST-2021-R012265
Ex vivo characterization of the drug susceptibility of malaria parasites in Uganda (Ex vivo study)
REFNo: HS4481ES

Primary objective
1. To characterize the ex vivo drug susceptibility of P. falciparum isolates collected from multiple sites in Uganda.
Secondary objectives
1. To characterize mutations that mediate drug resistance in P. falciparum isolates collected from multiple sites in Uganda
2. To characterize mutations that mediate drug resistance in banked P. falciparum previously collected from multiple sites in Uganda.
3. To culture, adapt and store P. falciparum isolates to enable studies of mechanisms of antimalarial drug resistance.
4. To measure drug levels in serum or plasma to help to understand treatment responses.

Uganda 2024-07-09 18:35:24 2027-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Diana Namumbejja Abwoye
ID:
Preventive medicine for displaced persons/refugees residing in Palabek settlement
REFNo: SS2818ES

To understand the experiences of refugees in Palabek resettlement with preventive healthcare through in-depth interviews,To explore knowledge, beliefs and attitudes of preventive healthcare among refugees living in Palabek resettlement through in-depth interviews, The long-term goal is to obtain a deeper understanding of how refugees living in Palabek resettlement camp perceive and utilize preventing medicine and inform stakeholders in the camp of any gaps or needs that may improve access and care. It is imperative to understand refugees’ perceptions and experiences with preventive medicine and establish which aspects of their refugee experience may influence utilization of preventive healthcare when available.,
USA 2024-07-09 18:33:18 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
The impact of the World Food Program (WFP) indirect conditional contracts
REFNo: SS2800ES

The research seeks to assess the impact of WFP's indirect conditional contracts on (maize) value chain outcomes such as access to reliable markets, value chain transformation and upgrading, welfare of the participating actors, and the scalability of the policy.
Belgium 2024-07-09 18:28:29 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
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