Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOSEPH Ngonzi
ID:
Quality Improvement Initiative in the Department of Obstetrics and Gynaecology
REFNo: HS967ES

1) To measure current health outcomes in the unit
2) To describe and analyze current process, behaviors, resources and availability
3) To develop and implement changes in current practices to improve outcomes while maximizing resources.
4) To monitor and evaluate health outcomes in the department of OB/GYN

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Non-degree Award
Margaret Joanita Mutumba Nakalembe
ID:
Multi-level Analysis on Implementation of Low-Cost IVF in Sub-Saharan Africa: A Case Study of Uganda.
REFNo: HS1214ES

The objective of this study is to explore how LCIVF has been implemented in the public health system of Uganda. The more specific questions include; 1) How has LCIVF been operationalized at the micro-level within the clinical practice? 2) How has the public hospital at the meso-level organized itself to facilitate the implementation and provision of LCIVF? 3) How have macro-level factors influenced the implementation of LCIVF within the public health system? 4) How effective has the implementation of LCIVF been in addressing accessibility and affordability of infertility services in Uganda?
 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 MUTATIONAL PROFILE OF TRIPLE NEGATIVE BREAST CANCER IN WOMEN SEEKING CARE AT THE UGANDA CANCER INSTITUTE
REFNo: HS1264ES

1. To describe the mutational profile of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
2. To describe the relationship between the mutational load and the primary tumor size of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
3. To describe the differences in mutational profile by histological type in patients with triple negative breast cancer in women seeking care at the Uganda Cancer Institute

 Uganda 2021-03-12 2024-03-12 Medical and Health Sciences Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 An Evaluation of the Pediatric Care Process in Uganda for Improvement of Quality of Care
REFNo: HS1227ES

The primary objective of this study is to evaluate the typical pediatric care process at a representative sample of hospitals in Uganda
 Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot
ID:
Severe MAlaria A Research and Trials consortium: A protocol for a prospective case control observational study
REFNo: HS1231ES

To characterise the contemporary epidemiology (including features at presentation and the diagnostic and treatment pathway) of severe malaria presenting to hospital for admission in children in Africa, through conducting a prospective multicentre observational study across 7 sites in 6 countries, enrolling two cohorts of hospitalised children (i.e. stratified) with severe and non-severe malaria. For this study, severe malaria will be defined as children with a positive POC pHRPT2 test (Paracheck) meeting WHO criteria or Teule criteri. For severe malaria, we will characterise the proportions presenting with different severe complications, or combination of any of or all of these, and compare these proportions across sites. Secondary Objectives i. To compare baseline characteristics of admitted children with severe and non-severe malaria. ii. To document time from presentation to the hospital ‘gateway’ (e.g. outpatients or emergency/triage centre) to ward admission and time to first dose of parenteral artesunate to assess whether delays in initiating definitive antimalarial treatment could contribute to malaria severity. iii. To estimate the incidence of significant post-discharge events to day-180 including readmission (all-cause and for malaria (i.e. relapse)) and all-cause mortality in severe and non-severe malaria. iv. To develop (year 1) and evaluate (years 2 and 3) a point-of-care quantitative plasma Plasmodium falciparum histidine-rich protein2 (pfHRP2) test for estimating total body parasite burden, which could be used to swiftly identify those at greatest risk of poor outcomes.
Uganda 2021-03-11 2024-03-11 Medical and Health Sciences Non-degree Award
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