Yahaya Gavamukulya
ID: UNCST-2019-R001017
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EVALUATION OF THE ANTI-SARS-CoV-2 ACTIVITY OF COMPOUNDS FROM Tephrosia linearis, Zanthoxylum chalybeum and Albizia coriaria AND FORMULATION OF HERBAL PRODUCT(S) FOR MANAGEMENT OF COVID-19
REFNo: HS1222ES
The general objective
To evaluate the antiviral potential of Tephrosia linearis, Zanthoxylum chalybeum and Alibizia coriaria, against SARS-CoV-2 and formulate herbal product(s) for management of COVID -19.
Specific objectives
i. To determine the in vitro anti-SARSâ€CoVâ€2 activity of the three selected medicinal plants in singular and in combination using SARSâ€CoVâ€2 infected mammalian cell lines (VeroE6).
ii. To determine the cytotoxicity and acute toxicity of the active medicinal plant(s) on mammalian cell lines (VeroE6) and swiss albino mice respectively.
iii. To determine the effects of the extracts on the immunological profile of cell lines
iv. To formulate and evaluate herbal product (s) from the most active medicinal plants for management of COVID-19.
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Uganda |
2021-03-15 |
2024-03-15 |
Medical and Health Sciences |
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Non-degree Award |
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Kelly Mannion Ray
ID:
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Understanding how variation in food effort and intake correlate with tool use in Bugoma Forest Chimpanzees
REFNo: NS155ES
To understand the potential drivers of tool use and how ecology plays a role
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USA |
2021-03-15 |
2024-03-15 |
Natural Sciences |
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Degree Award |
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Allen Kabagenyi
ID:
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Adolescent Motherhood, Vulnerability Assessment and Newborn care practices, in Eastern Uganda (AMNEP)
REFNo: HS1248ES
The general objective of this study is to develop and test adolescent motherhood vulnerability assessment tool and to examine the knowledge, behavioral practices and perceptions of maternal and new born care among adolescent mothers in Luuka District.
Specific objectives
1. To examine the knowledge levels and awareness of maternal and newborn care among adolescent mothers and the community in Luuka District
2. To develop and test a community based adolescent mothers Vulnerability Assessment Tool
3. To assess the pre and postnatal maternal and newborn care practices and among adolescent mothers and the community in Luuka District
4. To explore the perceptions, vulnerability risk and barriers to unborn and newborn care management among adolescent mothers and the community in Luuka District
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Uganda |
2021-03-15 |
2024-03-15 |
Medical and Health Sciences |
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Degree Award |
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Sebastian Linnemayr
ID: UNCST-2021-R012696
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INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
REFNo: HS1286ES
We propose to test INMIND in a pilot, 3-arm randomized controlled trial (RCT) in Uganda with two intervention groups. All participants (including in the control group) will receive information about the importance of behavioral routines, as is part of the standard adherence counseling for treatment initiators, and create personalized ART adherence anchoring strategies. In the first intervention group, participants will additionally receive text messages to keep adherence and their anchoring strategy salient. In the second group, we add small incentives awarded conditionally on taking ART pills within a time window that corresponds to participants’ personalized anchoring strategy to increase the immediate rewards of adherence.
The Specific Aims
1.Develop the intervention using the ADAPT-ITT framework and evaluate the feasibility and acceptability of INMIND.
2: Test the preliminary effectiveness of the intervention, including the relative effectiveness of two different implementation approaches
3. Collect data in preparation for a subsequent R01 application
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USA |
2021-03-15 |
2024-03-15 |
Medical and Health Sciences |
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Non-degree Award |
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Dickens Akena Howard
ID: UNCST-2019-R000179
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The effect of psycho-education on clinical outcomes among patients with a first episode psychosis in central Uganda - A pilot randomized control trial
REFNo: HS1026ES
The study objectives are to (a) Conduct formative work and develop a manual for delivering psycho-education messages by Village Health Team (VHTs) members to individuals with first episode psychosis (FEP) and their families in central Uganda. (b) Examine the efficacy of psycho-education on symptom severity, stigma and retention in care. (c) Document feasibility and acceptability of implementing this intervention as well as barriers to its implementation
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Uganda |
2021-03-12 |
2024-03-12 |
Medical and Health Sciences |
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Non-degree Award |
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