Barbara Mukasa
ID:
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Evaluating the Glycemic Effects of Dolutegravir (DTG) Among Patients Receiving Dolutegravir Based Regimens at Mildmay Uganda ART sites : A Prospective Cohort Study
REFNo: HS1273ES
1.To determine the incidence of hyperglycaemia among patients receiving DTG based regimen at Mildmay Uganda supported sites.
2.To determine the association between previous NRTI or NRTtI exposure and the incidence of hyperglycemia among patients on TLD.
3.Evaluate predictors of hyperglycaemia among patients on TLD.
4.Describe other adverse events reported by study participants during the study period.
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Uganda |
2021-03-26 |
2024-03-26 |
Medical and Health Sciences |
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Non-degree Award |
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Agnes Kiragga
ID:
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Community Pharmacies for Assessing STI Prevalence using Point of Care diagnostics study (COPHAS)
REFNo: HS1274ES
Aim 1: To estimate the prevalence of curable STIs and HIV among persons accessing health services at community pharmacies in Kampala and Wakiso Districts.
Aim 2: To determine the feasibility and uptake of pharmacy-based specimen collection and POC testing for curable STIs and HIV among persons seeking health care services at community pharmacies in Kampala and Wakiso Districts. Uptake will be measured among the three groups of persons i.e. Persons seeking EC (group 1), clients with STI symptoms (group 2) and persons without STI symptoms (group 3)
Secondary quantitative aims:
Aim 3: To determine treatment completion among persons diagnosed with an STI at the community pharmacies in Kampala and Wakiso Districts.
Aim 4: To determine linkage to care and ART initiation among newly diagnosed HIV positive persons at the community pharmacies in Kampala and Wakiso Districts.
Aim 5: To determine the baseline and 3-month knowledge about STI and STI treatment guidelines, and principles of antimicrobial stewardship of pharmacy staff. In addition, to assess the acceptability of POC STI diagnostics collocated with the pharmacy, to pharmacy owners and staff.
Qualitative aims
Aim 6: To assess the acceptability and client satisfaction of STI and HIV testing at community pharmacies in Kampala and Wakiso Districts.
Partner notification sub-study
Aim 7: To determine the effect of technology-supported partner notification and treatment initiation using Call for LifeTM technology among persons diagnosed with an STI or HIV at community pharmacies.
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Uganda |
2021-03-26 |
2024-03-26 |
Medical and Health Sciences |
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Non-degree Award |
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Moses Adriko
ID: UNCST-2019-R001787
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Information and Evidence Rapid Needs Assessment for COVID-19 in Uganda
REFNo: HS1285ES
A rapid needs assessment gives insights about the dissemination and utilisation of information and evidence related to the coronavirus (COVID-19) pandemic by individuals engaged at various levels of public health. The use of timely and accurate information about COVID-19 by public health workers will help to support the population in risk reduction through community education and the adoption of protective behaviours. As the outbreak progresses, it is important to understand: how health workers are getting their information (the sources); if the dissemination of official guidance is received, how it is perceived, and if it is followed; and the gaps in information and evidence at the subnational level; identify needs related to community and health facility COVID-19 information materials. Developing an understanding of and monitoring these issues will increase the use of timely and accurate information, and ultimately improve the dissemination of timely and accurate information to the population. The objectives of the project are as follows:
(1) To understand the different sources of information used by health workers in decision making on COVID-19.
(2) To identify the gaps in the dissemination of accurate information in the management of COVID-19 in Uganda.
(3) To improve the dissemination of timely and accurate information to the population about COVID-19 in Uganda.
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Uganda |
2021-03-26 |
2024-03-26 |
Medical and Health Sciences |
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Non-degree Award |
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Peter Olupot-Olupot
ID:
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H-PRIME
Hydroxyurea - Pragmatic Reduction In Mortality and Economic burden
REFNo: HS818ES
TRIAL OBJECTIVES
The primary objective of the trial is to identify pragmatic, effective, safe and acceptable interventions to reduce short and longer-term mortality and morbidity in children with SCD in sub-Saharan Africa. There are three hypotheses being tested
1. [Randomisation, R1] Daily oral hydroxyurea at a fixed weight-band based dose given with clinically driven (rather than routine scheduled) laboratory monitoring, without titrating doses to the MTD, will reduce all-cause mortality compared with placebo
2. [R2] Enhanced antimalarial prophylaxis will reduce malaria-associated hospitalisation vs standard of care (SOC) (open-label)
3. [R3] Enhanced antimicrobial prophylaxis will reduce all-cause hospitalisation vs SOC (open-label)
Secondary objectives include
 To determine the efficacy of the strategies above on other measures of morbidity
 To determine the safety and tolerability of the strategies above
 To identify the most cost-effective interventions to reduce mortality and morbidity, and assess their budget impact
 To investigate the cardiac safety of DHA-PQP in children with sickle cell disease
 To investigate the resistance patterns of malaria parasites acquired by children on different forms of malaria prophylaxis
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Uganda |
2021-03-24 |
2024-03-24 |
Medical and Health Sciences |
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Non-degree Award |
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Emmanuel Bizimungu
ID:
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The role of incentives for adoption of climate-smart agricultural innovations: An experimental evaluation in Uganda
REFNo: SS502ES
The main objective of this study is to assess the effectiveness of the incentives for the adoption of Climate-smart Agricultural (CSA) innovations, and ensuing impacts on farming systems resilience and household welfare, and examine the effects of weather, market, and payment uncertainties on investments in CSA innovations.
Specifically, this research will:
1. Assess the effects of different bundles of ‘push’ and ‘pull’ incentives on adoption intensity of climate-smart agricultural practices and technologies;
2. Determine smallholders’ behavioral responses to shocks and examine the extent to which uncertainties regarding weather, market and, timing of payment influence smallholders’ decisions to invest in inputs with/without incentives;
3. Analyze the effects of CSA adoption for intra-household decision-making;
4. Assess the impacts of CSA practices and technologies on farming systems’ resilience, factor productivity, revenues, income and, nutrition.
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Uganda |
2021-03-24 |
2024-03-24 |
Social Science and Humanities |
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Degree Award |
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