Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
SYLVESTER MUBIRU
ID:
SUPPORTIVE AND NURTURING PARENTING DURING CLIMATE STRESS PROGRAM IMPACT EVALUATION
REFNo: SS2645ES

The main goal of this research proposal is to provide rigorous evidence that will allow the team to respond the following research questions: 1. Is there a relation between caregiver-child interactions and reductions in violence against children? 2. Is there an association between caregivers’ mental health and emotional wellbeing and caregiver-child interactions? 3. Is there a correlation between caregiver behaviors and indirect improvements in children’s behaviors and development? 4. What potential mechanisms (e.g., household dynamics, parental self-efficacy, networks, economic deprivation) are associated with variations in caregiver-child interactions and children\'s development? 5. Are variations in caregiver-child interactions and children\'s development correlated with parents’ initial mental health status, parenting skills, and climate stress incidence?,
 Uganda 2024-05-23 13:54:32 2027-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Musoke
ID:
Assessment of leadership and management competencies among health managers in Wakiso District, Uganda
REFNo: HS4164ES

To assess the leadership and management competencies among health managers in Wakiso District Local Government, Uganda. Specifically, the study will: (1) determine the leadership and management competencies among the health managers; (2) identify the leadership and management practices among the health managers; and (3) explore the barriers and facilitators to effective leadership and management among the health managers.
Uganda 2024-05-23 13:50:34 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
 Stage, therapy and outcome in adult cancer patients in selected African countries: a population-based registry study
REFNo: HS4279ES

1. To obtain information on stage at diagnosis for selected adult cancers ,3. To obtain information on therapy and patient journey how these factors varied according to year of diagnosis in the period 2017-2021,2. To obtain vital status through (active and passive) follow-up for 19 cancers. ,1. To determine cancer survival for 19 selected cancers and factors affecting cancer survival.,
 Uganda 2024-05-23 13:47:29 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 ACCESS AND USAGE OF DIGITAL HEALTH TOOLS. OPPORTUNITIES AND CHALLENGES TO SUPPORT GENDER EQUALITY AND UNIVERSAL HEALTH COVERAGE IN UGANDA
REFNo: HS4295ES

Explore the strengths and weaknesses of existing digital health policies and structures in addressing gender inequalities and enhancing Universal Health Coverage for women and girls.,Explore the opportunities and challenges for increasing universal health coverage among women and girls using digital health tools. ,Explore gender inequalities associated with digital health tools among women and girls in Uganda.,Analyze the strengths and weaknesses of current digital health tools for women and girls in Uganda.,This study explores digital health tools\' influence on gender equality and Universal health coverage in Uganda. This work will also help identify digital health tools that can be utilized to address gender inequalities and increase access to health care.,
 Uganda 2024-05-23 13:45:18 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
 Multinational Observational Cohort of HIV and other Infections (MOCHI)
REFNo: HS2362ES

To determine the HIV incidence rate in a cohort of individuals who are vulnerable to HIV across multiple sites.
Uganda 2024-05-23 13:43:27 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Duke Fan-Chiang
ID: UNCST-2023-R001922
 THE IMPACT OF CROSS-SECTOR INTERVENTION ON CONFLICT-AFFECTED CHILDREN’S MENTAL HEALTH IN PROTRACTED HUMANITARIAN SETTINGS. THE CASE OF CHILDREN ON REFUGEE SETTLEMENTS IN UGANDA
REFNo: SS2118ES

Explore the impact on the mental health well-being of conflicted-affected children by integrating MHPSS interventions into the existing child protection activities in the Bidibidi settlement by

1. Learning about the extent that MHPSS interventions be effective in a protracted humanitarian setting?

2. Identifying the relationships between mental health and child protection indicators in a protracted humanitarian setting such as the Bidibidi settlement?

3. Identifying the influential factors to promote a positive impact during the implementation process?

Taiwan 2024-05-23 13:35:15 2027-05-23 Social Science and Humanities Non-Clinical Trial Degree Award
Lydia Nakiyingi
ID: UNCST-2022-R010102
 Multi-pathogen wastewater surveillance in Uganda with CRISPR Cas 12/13 assay: A pilot study
REFNo: HS4139ES

The proposed research will test the overarching hypothesis that wastewater pathogen burden measured by SHINE and CARMEN CRISPR-based platforms will positively correlate with the prevalence (for routine pathogens) and incidence (for outbreak pathogens) within our catchment areas,Our second objective involves leveraging the massive multiplex CARMEN assay to broadly survey for high-priority outbreak pathogens such as Ebola, yellow fever, Vibrio cholera and Mycobacterium tuberculosis in regional Kampala wastewater sources (East Bugolobi treatment plant and Nakivubo channels). As an advantage, CARMEN reactions have already been developed for all of these pathogens, which are also shed in human excrement,As our first objective, we propose to assess the performance of the field-deployable SHINE CRISPR assay (benchmarked against CARMEN) in estimating the prevalence of diverse respiratory and food-borne pathogens such as Mycobacterium tuberculosis, common respiratory viruses, and antimicrobial-resistance genes (e.g. Carbapenem-resistant Enterobacteriaceae [CRE], vancomycin-resistant enterococci [VRE]) using wastewater samples from a local sewage line (Mulago Hospital). ,
 Uganda 2024-05-23 13:32:28 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Namujulirwa Carolyn
ID:
PASTORAL CARE AND HOLISTIC EDUCATION IN CATHOLIC SECONDARY SCHOOLS: A CASE OF THE COMBONI MISIONARIES IN KAMPALA ARCH DIOCESE AND LIRA DIOCESE
REFNo: SS2550ES

iii. What are the legacies of Comboni missionary pastoral care models applied in secondary schools in Kampala arch diocese and Lira diocese and how can they be applied in other catholic dioceses in Ugandan catholic secondary schools?,ii. To what extent do pastoral care structures and strategies influence the promotion of holistic education in the Comboni Missionaries secondary schools in Lira and Kampala arch diocese and Lira diocese?,i. What are the unique characteristics of pastoral care employed in the promotion of holistic education in Comboni missionary secondary schools in Kampala arch diocese and Lira Diocese? ,The purpose of the study is to investigate the role Comboni missionaries played in the promotion of holistic education through pastoral care in Catholic secondary schools in Kampala Arch diocese and Lira diocese,
 Uganda 2024-05-23 13:14:19 2027-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Therapeutic Drug Monitoring for Antimicrobial Agents for People Living with HIV (TAP trial)
REFNo: HS3909ES

1.To determine the concentrations of selected antimicrobial agents in people living with HIV requiring antimicrobial therapy. 2. To assess the utility of therapeutic drug monitoring in achieving therapeutic targets for people living with HIV receiving rifampicin and isoniazid for treatment of tuberculosis. 3. To develop and validate a population pharmacokinetic-pharmacodynamic model for use during therapeutic drug monitoring for selected antibiotics used among PLWH
 Uganda 2024-05-23 13:12:37 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CATHERINE ABBO
ID:
Implementing the MHPSS Minimum Service Package for infectious disease outbreaks in Uganda – an evaluation study
REFNo: HS3915ES

. To evaluate the feasibility, acceptability, appropriateness, fidelity and uptake of a set of MHPSS interventions in outbreak response in Uganda (through live implementation or SimEx), ,. To develop an implementation plan that includes capacity strengthening activities necessary to implement a set of MHPSS interventions for outbreaks in Uganda successfully ,1. To conduct a gap analysis and prioritization, using MSP, to successfully identify a contextualized set of interventions for outbreak response in Uganda ,To develop, implement and evaluate a suite of tailored MHPSS interventions supporting outbreak preparedness and response in Uganda using the Minimum Service Package. ,
 Uganda 2024-05-23 10:29:39 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sam Ononge
ID: UNCST-2020-R000328
 THE ENHANCED PRODUCT DEVELOPMENT AND PILOT TESTING OF A SMART POSTPARTUM HAEMORRHAGE VOLUMETRIC DRAPE FOR EARLY DETECTION OF POSTPARTUM HAEMORRHAGE DURING CHILD BIRTH.
REFNo: HS3959ES

4. To conduct safety testing of the electronic blood sensing module of the SMART PVD.,3. To evaluate the usability of the SMART-PVD with the midwives.,2. To assess the acceptability of the SMART-PVD among the women and midwives.,1. To determine the performance of the SMART PVD device in accurately estimating the volume of blood lost during delivery as well as timely alerts on the onset of a PPH case. ,To conduct a pilot feasibility study to evaluate the viability of the SMART PVD as a diagnostic device for timely and accurate diagnosis of Postpartum Haemorrhage after delivery.,
 Uganda 2024-05-23 10:25:06 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssinabulya
ID: UNCST-2021-R004352
 An mHealth implementation strategy to address the syndemic of mental illness, hypertension, and HIV in Uganda [Formative Phase: Syndemic Adapted Medly Uganda (SAMU)]
REFNo: HS3992ES

To determine through field testing, if the SAMU intervention is acceptable to patients and providers, Safe for patients, technically functional, stable, and reliable.  ,To adapt the Medly Uganda application for use with PLWH with HTN in Uganda, to address screening, diagnosis and linkage to care for common mental health conditions including anxiety disorder alcohol use disorder and depression,
 Uganda 2024-05-23 10:22:58 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anthony Mugeere Buyinza
ID:
In search of green jobs: voices of (unheard) young people and their aspirations, barriers and negotiations with work
REFNo: SS2539ES

motivations of seeking green jobs in Uganda.
2. To explore the key barriers that prevent young people from accessing green jobs.
3. To examine the ways young people navigate the barriers they encounter in their quest for green jobs and how the local, national, and international policy environment levels shape their opportunities to access green jobs.
4. To propose policy changes that could be implemented to better support the aspirations and needs of young people as regards green jobs.
 Uganda 2024-05-23 10:20:52 2027-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Arthur  Mpimbaza
ID: UNCST-2022-R008866
 A model health systems strengthening strategy to reduce malaria mortality in the Busoga sub-region, Uganda: a proof-of-concept trial
REFNo: HS3927ES

General Objective
To determine the viability of a model health system strengthening (HSS) strategy in improving the quality of malaria management services and empowering communities in Bunya East HSD, Mayuge district, Busoga sub-region.

2 Specific objectives
1. To determine the feasibility of implementing a model HSS strategy in improving the quality of malaria management services offered at facilities in Bunya East HSD.
2. To assess the acceptability of a model HSS strategy in improving the quality of malaria management services offered at facilities in Bunya East HSD.
3. To develop a process of engaging and empowering communities’ to take-up appropriate malaria health seeking behavior at a village in Bunya East HSD.
4. To assess the preliminary effectiveness of the model HSS strategy on outcomes related to appropriate malaria case management at facilities and the community in Bunya East HSD.


Uganda 2024-05-15 18:19:15 2027-05-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sunny Okoroafor C
ID:
ASSESSMENT OF PATIENT SAFETY PRACTICES IN UGANDA
REFNo: SS2596ES

To determine the status of the patient safety practices in Uganda.,
 Nigeria 2024-05-14 9:17:02 2027-05-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Racheal Angom
ID: UNCST-2023-R007485
 ELECTRONIC TREATMENT SCHEDULING AND PSYCHOSOCIAL INTERVENTIONS TO REDUCE TREATMENT ABANDONMENT AMONG CHILDREN AND ADOLESCENTS WITH CANCER IN UGANDA.
REFNo: HS3944ES

To develop a comprehensive psychosocial support program through collaboration among UCI, UCCF and other civil society organizations to decrease treatment abandonment. ,To determine factors that influence treatment abandonment for UCI patients,To determine parent/caregiver reasons for treatment abandonment ,To Create a tracking system for patient treatment appointments to identify initial missed treatment visits (risk for treatment abandonment) and actual treatment abandonment using a time-sensitive electronic system [Research Electronic Data Capture (REDCap)] , To Create a tracking system for patient treatment appointments to identify initial missed treatment visits (risk for treatment abandonment) and develop a comprehensive psychosocial support program through collaboration among UCI, UCCF and other civil society organizations to decrease treatment abandonment. actual treatment abandonment using a time-sensitive electronic system [Research Electronic Data Capture (REDCap)] and,
 Uganda 2024-05-14 9:12:26 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
 Clinical validation of novel microfluidic-based technologies for detection of Lower Respiratory Tract Infections (HOLICARE Trial)
REFNo: HS3718ES

1. To determine the sensitivity and specificity of the Multi- Lateral Flow Test (LFT) using nasopharyngeal swab with visual detection and using a mobile phone as a reader.
To determine the sensitivity and specificity of the Multi- Lateral Flow Test (LFT) using nasopharyngeal swab with visual detection and using a mobile phone as a reader.
To validate the clinical performance, sensitivity and specificity of a Point of Care (POC) platform that performs pathogen detection (bacteria, fungi) using microfluidic- Loop mediated isothermal amplification (LAMP) isothermal amplification and quantification of host-response biomarkers using a bead-based immunoassay, by comparing its results to those of reference standard methods:benchtop Polymerase Chain Reaction (PCR) and Enzyme Linked Immunosorbent Assay (ELISA), respectively.
To assess whether the POC-Instrument can be inserted in the patient management procedure to assist clinical decision-making.
(2) To assess the hands-on usability of the POC-Instrument and receive feedback by end-users for future implementation in clinical practice.

 Uganda 2024-05-14 9:08:56 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jeremiah Alisengawa
ID: UNCST-2022-R009718
 MANAGEMENT LEVEL SUPPORT SYSTEMS AND STRATEGIC PLAN IMPLEMENTATION IN CHARTERED PRIVATE UNIVERSITIES IN UGANDA. A SURVEY ON NDEJJE AND NKUMBA UNIVERSITIES.
REFNo: SS2199ES

4. To investigate the self-involvement role of action-level management in the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,3. To examine the operationalization role of operations-level management during the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,2. To assess the coordination role of middle-level management in the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,To examine the support role of top-level management in the implementation of strategies of Ndejje and Nkumba Universities in Uganda.,
 Uganda 2024-05-14 9:05:50 2027-05-14 Social Science and Humanities Non-Clinical Trial Degree Award
Jamon Van Den Hoek
ID: UNCST-2023-R006549
 Multi-sensor Mapping of Refugee Agricultural Land-Cover/Land-Use Change Hotspots in Uganda
REFNo: A414ES

Map changes in crop area and type in refugee-hosting districts with multi-sensor satellite time series analysis and transfer learning.
 USA 2024-05-14 9:03:35 2027-05-14 Agricultural Sciences Non-Clinical Trial Non-degree Award
Ria  Kapoor
ID:
From Migrant to Citizen to Refugee: a Global History of the 1972 Ugandan Asian Expulsion
REFNo: SS2625ES

I will assess the impact of a connected, sovereign Afro-Asian world on the international order and attendant structures. Within the long-term aim to understand citizenship, diaspora, and immigration my immediate focus is the 1972 Ugandan Asian Expulsion. From Migrant to Citizen to Refugee traces how a transformation of citizenship across the British Empire took place, with the expulsion of the Ugandan Asians by Idi Amin in 1972 and their resettlement in Britain, Canada, and India following the decolonisation of East Africa. It emphasises this transformation of citizenship as part of a worldwide process of decolonisation.

The project also explores how these changes to citizenship also changed UN-led practices. I explore how humanitarian assistance was provided, with the international community becoming complicit in the social reconfigurations enacted by postcolonial states. Deemed ‘refugees’ in some cases and ‘citizens’ in places like India, Canada and the UK, Uganda’s Asians’ citizenship in other areas of the former British Empire became fluid in the discourse of immigration and belonging in the 1970s as a result of postcolonial citizenship itself being transformed.


India 2024-05-14 9:02:46 2027-05-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
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