victoria nakibuuka
ID: UNCST-2020-R014741
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Developmental care packages to improve neonatal outcomes – a multidisciplinary approach
REFNo: HS1254ES
To survey current knowledge, practices and attitudes towards developmental care to assess potential barriers and facilitators to implementing and integrating developmental To observe current practice in NICU’s care packages in NICU’s in LMIC
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Uganda |
2021-04-15 |
2024-04-15 |
Medical and Health Sciences |
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Non-degree Award |
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Cissy Kityo
ID: UNCST-2021-R013663
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D3 (PENTA 21)
A randomised non-inferiority trial with nested PK to assess DTG/3TC fixed dose formulations for the maintenance of virological suppression in children with HIV infection aged 2 to <15 years old
REFNo: HS1288ES
The overall aim is to evaluate two-drug therapy with DTG/3TC FDC given once daily in comparison with triple-drug ART in HIV-1 infected children and adolescents who are virologically-suppressed on their ART regimen.
PRIMARY OBJECTIVE
To assess whether DTG/3TC is non-inferior to SOC, consisting of an anchor drug (NNRTI, PI or INSTI) and 2 NRTIs, in terms of virological suppression
HYPOTHESIS
Switching to DTG/3TC will provide non-inferior virological suppression to remaining on SOC over 96 weeks.
SECONDARY OBJECTIVES
 To evaluate clinical and laboratory adverse events associated with the trial antiretrovirals
 To evaluate new resistance mutations in participants with virological rebound (confirmed VL≥50 copies/mL)
 To assess low level viraemia and virological reservoirs
 To evaluate adherence, tolerability, acceptability, sleep and health-related quality of life
 To evaluate and model the pharmacokinetics and pharmacodynamics of dispersible and film-coated fixed-dose DTG/3TC formulations in children weighing 6-<40kg using WHO weight band-aligned dosing
 To evaluate cost-effectiveness of treatment maintenance with DTG/3TC FDC if DTG/3TC is shown to be non-inferior to SOC
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Uganda |
2021-04-15 |
2024-04-15 |
Medical and Health Sciences |
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Non-degree Award |
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Godfrey Siu
ID: UNCST-2021-R005439
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The impact of COVID-19 on domestic care work in Uganda
REFNo: SS770ES
1. To determine the burden and patterns of domestic care work during the COVID-19 response phase.
2. To determine the barriers and facilitators of domestic work during the lockdown.
3. To examine the effects of COVID-19 on the social, economic and family relations.
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Uganda |
2021-04-15 |
2024-04-15 |
Social Science and Humanities |
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Non-degree Award |
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James Katungyi
ID:
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The effect of daytime circadian thermal variability on the well-being of building occupants. A case study of office type building occupants in Kampala.
REFNo: SIR41ES
The research objective is to compare short and long-term impacts, of variable indoor thermal conditions (which mimic the outdoor variability) versus static thermal conditions, on the wellbeing of building occupants.
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Uganda |
2021-04-13 |
2024-04-13 |
Engineering and Technology |
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Degree Award |
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Susannah Mayhew Harding
ID:
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Rapid Qualitative Research to support integrated environment, livelihoods and health programming in Uganda (“Supporting Integrated Programmingâ€)
REFNo: HS1137ES
The research objectives are to:
1) Determine the environmental, livelihood and health challenges facing communities living in/near Rushebeya wetland;
2) Identify how, and through what structures and processes, people in these communities make decisions about and respond to identified challenges; and identify whether these responses have changed over time;
3) Examine whether there are differences in responses by age, sex or socio-economic background.
4) Identify messages and intervention activities to address the challenges felt by different groups in these communities.
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UK |
2021-04-13 |
2024-04-13 |
Medical and Health Sciences |
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Non-degree Award |
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