Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Francis Eswap
ID:
Skepticism Over Refugee Quest to Realise the Right to Skills Development; the Case of South Sudan Adolescents in Adjumani-Uganda
REFNo: SS2659ES

1 To find out if adolescent refugees are accessing skills training programmes in a supportive social ecological system and if there are barriers and whether human rights legal regimes are effectively applied for their realisation of the right to skills development.
2 To assess skills training programmes for adolescent refugees to realise their right to skills development
3 To evaluate whether there is a Social Ecological System that supports adolescent refugees’ realisation of the right to Skills Development
4 To analyse the Barriers to adolescent refugees’ realisation of the right to skills development
5 To Examine the effectiveness of legal regimes in the Adolescent Refugee realisation of the Right to Skills Development

Uganda 2024-05-31 17:52:27 2027-05-31 Social Science and Humanities Non-Clinical Trial Degree Award
Ponsiano Ocama
ID: UNCST-2019-R001799
Assessment of Research Integrity Environment at Makerere University College of Health Sciences
REFNo: HS4131ES

To explore students and staff’s knowledge and attitudes towards research misconduct at MakCHS,To assess the magnitude of focus on research integrity issues among MakCHS regulatory structures,To determine the factors associated with research misconduct practices at MakCHS.,To identify the different types of research misconduct practices at MakCHS.,To assess the current research integrity frameworks at Makerere University College of Health Sciences and develop interventions to address research misconduct.,
Uganda 2024-05-31 17:48:32 2027-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
Understanding the Barriers to Adoption and Active Use of Digital Services Provided via FarmDirect
REFNo: HS4305ES

Objectives (a) General Objective: The overarching objective of this study is to diagnose and solve the behavioral barriers and leverage enablers to the adoption and active use of FarmDirect’s services amongst farmers in Uganda. (b) Specific Objective: To explore how we increase the awareness of FarmDirect amongst unregistered farmers 1. To identify the sought-after attributes of their desired marketing channel 2. To explore the levels of comprehension and interest in a digital marketing channel 3. To understand the intention and willingness to undertake actions to use a digital marketing channel
Uganda 2024-05-30 11:30:32 2027-05-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
Usability Evaluation of the ANC Panel (Professional Use)
REFNo: HS4262ES

The primary objectives of this usability study are:
• To evaluate professional users’ ANC Panel test labelling comprehension (n=15 healthcare professionals). This evaluation will assess the professional users’ understanding of the key messages from the ANC Panel product packaging and labelling. The evaluation will be questionnaire-based and will comprise an evaluation of the users’ understanding of:
o The key warnings and test limitations and/or restrictions
o The test procedure
o The test result interpretation

• To evaluate the ability of professional users to interpret the ANC Panel test results (n=15 healthcare professionals). This evaluation will assess the professional users’ ability to interpret pre-prepared, static ANC Panel test results. The results will comprise a range of test results, including weak-positive results and tests with failed control lines. Each user will interpret five different test results, with three tests in each test result, in randomised order.

UK 2024-05-30 11:27:23 2027-05-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Awori Siryoyi
ID:
Determinants of export performance of maize farmer organizations in Busia district, Uganda
REFNo: A440ES

To establish the effect of import bans and tariffs on the export performance of maize farmer groups in Busia district, Uganda. ,To illustrate the effect of infrastructural development on the export performance of maize farmer groups in Busia district, Uganda,To demonstrate the effect of middlemen on the export performance of maize farmer groups in Busia district, Uganda,To establish the effect of farmer group capacity on the export performance of maize farmer groups in Busia district, Uganda. ,
Uganda 2024-05-30 11:26:40 2027-05-30 Agricultural Sciences Non-Clinical Trial Degree Award
Jerome  Barry Bamugaya
ID:
INCLUSIVE COMMUNITY GROUPS’ INITIATIVES TO SUSTAINABLE RURAL LIVELIHOOD SECURITY IN TESO SUB-REGION IN UGANDA
REFNo: SS2597ES

I. To establish the contribution of local community groups’ initiatives in reducing livelihood insecurities in Teso region in Uganda
II. To ascertain men and women’s perceptions and views on local groups’ initiatives towards rural livelihood security
III. To determine existing challenges, and threats that impede community initiatives to sustainable rural livelihoods among Iteso
IV. To establish applicable and tenable model for effective community groups’ operations

Uganda 2024-05-30 11:23:14 2027-05-30 Social Science and Humanities Non-Clinical Trial Degree Award
WATAKA WILLIES
ID:
HUMAN RESOURCE PRACTICES AND EMPLOYEE TURNOVER IN CITY COUNCILS OF MBALE AND JINJA, EASTERN UGANDA
REFNo: SS2476ES

iv) To establish the effects of employee motivation on employees’ turnover in City Councils of Mbale and Jinja.,iii) To examine the effects of employee health and safety on employees’ turnover in City Councils of Mbale and Jinja.,ii) To establish the effects of employee career growth management on employees’ turnover in City Councils of Mbale and Jinja.,i) To determine the effects of employee reward management on employees’ turnover in City Councils of Mbale and Jinja.,The purpose is to assess how Human Resource Practices have influenced employees’ turnover in City Councils in Eastern Uganda.,
Uganda 2024-05-30 10:41:59 2027-05-30 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Byarugaba Karuhize
ID: UNCST-2023-R006496
Severe acute respiratory infections (SARI) surveillance in hospitalized patients in Uganda
REFNo: HS4166ES

i) To better understand SARI etiology (influenza and other respiratory viruses), severity and risk factors among hospitalized patients with SARI from all age groups
ii) Contribute to Uganda’s and global response and management of SARI
iii) Contribute to international capabilities and collaboration to integrate clinical virological and genomic influenza and other respiratory pathogens surveillance data through the WHO Global Influenza Surveillance and Response System (GISRS) to support intervention and better SARI management and response including influenza vaccine selection, vaccine escape as well other respiratory virus vaccines
iv) Support international alert and response system for emerging strains of pandemic potential

Uganda 2024-05-29 9:45:45 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Secondary use of Uganda Population-based HIV Impact Assessment (UPHIA) samples and associated data for micronutrient surveillance
REFNo: HS4333ES

2. Assess for associations between micronutrient status with HIV status and related indicators using 2020 - 2021 UPHIA metadata,1. Determine national and sub-national prevalence estimates for MND using 2020 - 2021 UPHIA samples,
Uganda 2024-05-29 9:42:49 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sherifah Nabikande
ID: UNCST-2022-R009631
Uptake of HIV prevention interventions among adolescent girls and young women in slum settings in Kampala district, Uganda
REFNo: HS4015ES

3) To explore the barriers and facilitators of condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,2) To determine the factors associated with condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,1) To determine the proportion of AGYW who use condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions in slum settings in Kampala district, Uganda,To determine the uptake of condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions and factors associated among AGYW in slum settings in Kampala district, Uganda ,
Uganda 2024-05-29 9:40:25 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
A randomized, open-label, multicenter study to compare efficacy, safety and tolerability of KLU156 with Coartem® in the treatment of uncomplicated Plasmodium falciparum malaria in adults and children ≥ 5 kg body weight followed by an Extension phase with repeated KLU156 treatment.
REFNo: HS3732ES

This study aims to confirm the efficacy, safety and tolerability of KLU156, a fixed dose combination of ganaplacide (KAF156) and a solid dispersion formulation of lumefantrine (lumefantrine-SDF), when administered once daily for three days in adults and children ≥ 5 kg body weight and ≥ 2 months of age suffering from uncomplicated P.Falciparum malaria (with or without other plasmodium spp. co-infection). In the Extension phase, the safety, tolerability and efficacy of repeated treatment with KLU156 will be assessed for a maximum of two years in patients who did not experience early treatment failure(ETF), who did not experience any study treatment-related SAE (Serious Adverse Event) previously and who gave informed consent to participate in the Extension phase.
Uganda 2024-05-29 9:37:35 2027-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Christine kisubi Esther
ID:
ENVIRONMENTAL JUSTICE IN UGANDA’S OIL AND GAS UPSTREAM SUB-SECTOR DECISION-MAKING
REFNo: SS2634ES

To critically examine the legal frameworks and their implementation concerning environmental justice and community participation in decision-making processes within Uganda\'s oil and gas upstream sub-sector.,
Uganda 2024-05-27 9:01:35 2027-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Nakacwa Patricia Florence
ID: UNCST-2024-R004518
Student\'s Academic Resilience and Competence Based Curriculum: A case study of Secondary Schools in Mukono and Kayunga District.
REFNo: SS2605ES

iv. To evaluate the moderating influence of emotional intelligence on the relationship between academic resilience and competency-based learning in secondary schools in Mukono and Kayunga districts.,iii. To analyze the effect of academic coordination on competency-based learning in secondary schools in Mukono and Kayunga districts.,ii.To examine the relationship between academic confidence and competency-based learning in secondary schools in Mukono and Kayunga districts.,i.To assess the relationship between academic commitment and competency-based learning in secondary schools in Mukono and Kayunga districts.,The study intends to examine the relationship between academic resilience and competency-based learning to develop a model to support quality education in secondary schools in Uganda.,
Uganda 2024-05-27 9:00:16 2027-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
HELLEN NAIGAGA
ID:
PHENOLOGY MONITORING AND SEASONAL WEATHER FORECASTING IN RELATION TO FARM MANAGEMENT IN UGANDA
REFNo: NS770ES

• To establish local knowledge on abrupt changes in plant phenological patterns • To assess how the use of phenological changes by farmers in weather forecasting impacts on farming activities and farm productivity • To examine the plant compounds and weather parameters which trigger Plant phenological changes • To develop strategies for linking local knowledge and scientific knowledge for future weather forecasting • To predict future weather changes based on plant phenological changes
Uganda 2024-05-27 8:58:04 2027-05-27 Natural Sciences Non-Clinical Trial Degree Award
FREDRICK MAKUMBI
ID:
Post-Phase II Yellow Fever Preventive Mass Vaccination Campaign Coverage Survey in Uganda
REFNo: HS4258ES

To explore individual and health system related factors influencing the non-receipt of yellow fever preventive mass vaccination campaign.,To identify the adverse effects following immunization (AEFI) during the yellow fever preventive mass vaccination campaign.,To assess factors associated with yellow fever preventive mass vaccination campaign uptake.,To determine the reach of the vaccination program and for each of the interventions like IEC, by age, residence (rural/urban), education, wealth, disability status and refugee status.,To measure post-campaign immunization coverage of yellow fever for persons aged 1 to 60 years old within the 6 phase II regions.,The main objective of this survey is to evaluate program performance by coverage, the reach of the program interventions of the yellow fever, and assess the equity of the program to ensure no one is left behind, and validate administrative data coverage at different levels; to further inform the implementation of the vaccination campaign, and provide evidence in each of the 6 phase-II regions (sub-national levels) in Uganda about population vaccination against yellow fever for persons aged 1 to 60 years.,
Uganda 2024-05-27 8:56:24 2027-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacqueline Kyosiimire-Lugemwa
ID: UNCST-2022-R005393
Epigenetic modifications in HIV-1 accessory and regulatory genes, Host genes and differential protein expression among LTNP and Rapid progressors from a Ugandan Cohort
REFNo: HS4047ES

Aim 1. Identify the differential expression of Epigenetic signatures of HIV-1 accessory and regulatory genes DNA methylation among African pediatric LTNP and Rapid progressors Aim 2. Identify the differential expression of Epigenetic signatures of the host genome DNA methylation among African pediatric LTNP and Rapid progressors. Aim 3. Identify the differential expression of plasma proteomic signatures among African pediatric LTNP and Rapid progressors. Aim 4. Establish protein-protein interactions and metabolite interaction networks among African pediatric LTNP and Rapid progressors.
Uganda 2024-05-23 14:57:54 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Achan Edwin
ID: UNCST-2023-R005498
Evaluation of the protective efficacy of a spatial repellent to reduce malaria prevalence in Uganda: Study protocol for a cluster-randomized double-blinded control trial: The Mossie-GO trial
REFNo: HS4196ES

The study’s primary objective is to demonstrate and quantify the protective efficacy (PE) of Mossie-GO, an active spatial repellent system disseminating transfluthrin, in reducing the prevalence of malaria infection in children ≤ 5 years of age.

The study’s secondary objective is to measure the impact of the intervention on entomological correlates of transmission including vector densities and host seeking behaviour. Insecticide resistance in the local mosquito population will also be explored.

Uganda 2024-05-23 14:23:11 2027-05-23 Medical and Health Sciences Clinical Trial Non-degree Award
Tonny Oyana Justus
ID:
A HOLISTIC APPROACH IN MANAGEMENT AND SURVEILLANCE OF LOWER RESPIRATORY TRACT INFECTIONS (LRTIS) THROUGH CONVERGENCE OF DIAGNOSTIC TECHNOLOGIES, CAPACITY BUILDING AND STAKEHOLDER ENGAGEMENT (HOLICARE)
REFNo: SIR330ES

1. To survey and describe the existing diagnostics approaches/ technologies applied in Uganda’s health System specifically for lower respiratory tract infections.
2. To develop an ICT-based medical data flow network
3. To validate the framework using diagnostic mobile API’s
Uganda 2024-05-23 14:00:03 2027-05-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Enerst Edozie
ID: UNCST-2023-R005516
DEVELOPMENT OF A MONITORING AND DETECTION PIPELINE FOR HUMAN ACTIVITIES AROUND TELECOMMUNICATIONS INFRASTRUCTURE USING ARTIFICIAL INTELLIGENCE - KIU-2023-280
REFNo: SIR337ES

4. To validate the developed system using publicly available human activity datasets. ,3. To design and implement an embedded sensor and alarm systems to curb theft and vandalism of optical fiber cable., 2. To develop a real-time artificial intelligent system based on YOLO Deep Learning for monitoring and detection of activity around an optical fiber cable. ,1. To develop anomaly activities datasets of pedestrians activity around telecoms infrastructure. ,This study aims to implement an efficient monitoring and detection of abnormal activities around telecommunications infrastructure using artificial intelligence based approach. ,
Nigeria 2024-05-23 13:58:11 2027-05-23 Engineering and Technology Non-Clinical Trial Degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
Scaling Inclusive Home-based Early Learning Initiative (SIHELI): Lessons from Uganda, Ghana and Liberia
REFNo: SS2607ES

3. Mobilize the knowledge and evidence on the scaled inclusive early learning play approaches to improve policy and practice in education systems.,2. Strengthen the capacities of parents, teachers, education officials and community members to support and sustain the use of play pedagogy in the established home based early learning centres. ,1. Generate knowledge and evidence on how to scale the impact of inclusive home based early learning approaches to promote inclusive early learning and school readiness. ,The project’s general objective is to generate evidence to contextualize and scale the impact of inclusive home-based early learning play approach to promote smooth transition from ECCE to primary school.,
Uganda 2024-05-23 13:56:14 2027-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
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