Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fatumo  Segun Adeyemi
ID:
Causal Relationship between Cardiometabolic traits and Chronic Kidney Disease in African Population.
REFNo: HS1730ES

1. To Identify genetic determinants of kidney function in continental Africa"
2. To investigate the predictive utility of Polygenic Risk Scores for Chronic Kidney disease in Africans.
3. To assess the causal effect of kidney function on cardiometabolic diseases using Mendelian Randomisation Approach.

UK 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geoffrey Beyihayo Akiiki
ID:
Native Chicken Project
REFNo: A154ES

To establish genetic markers associated with economic traits among indigenous chicken eco-types,To establish genetic and phenotypic parameter estimates for economic traits among indigenous chicken eco-types,To assess the genetic diversity of indigenous chickens eco-types based on mitochondrial DNA (mtDNA),To characterize indigenous chicken based on qualitative and quantitative phenotypic traits ,To characterize and identify genetic markers of egg and growth traits for selection of highly productive indigenous multipurpose chickens ,
Uganda 2021-11-15 2024-11-15 Agricultural Sciences Non-Clinical Trial Degree Award
David Guwatudde
ID: UNCST-2021-R008522
The Uganda Non-Communicable Diseases (NCD) Risk Factor Mobile Phone Survey - 2021
REFNo: HS1738ES

1.Evaluate the efficacy (as measured by the response rate), of conducting a mobile phone survey to collect data on the common NCD risk factors

2.Collect data on specific NCD disease conditions, and the self-reported NCD risk factors to support monitoring and evaluation of programs and policies in Uganda.

3.Generate comparable data from mobile phone surveys within Uganda over time.

4.Provide data to the Ministry of Health and other relevant ministries, and make recommendations on developing, improving, and enhancing prevention and response strategies to address NCDs and NCD associated disabilities in Uganda.
Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalyesubula Edward
ID: UNCST-2021-R012991
The prevalence of oral diseases and their associated factors in children and adolescents attending the diabetes clinic at Mulago
REFNo: HS1799ES

1. To determine the prevalence of dental caries among children and adolescents attending the diabetes clinic at Mulago.
2. To determine the prevalence of periodontal diseases among children and adolescents attending the diabetes clinic at Mulago.
3. To determine the associated risk factors for dental caries among children and adolescents attending the diabetes clinic at Mulago.
4. To determine the associated risk factors for periodontal diseases among children and adolescents attending the diabetes clinic at Mulago
Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
BREATHER Plus: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir- based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub-Saharan Africa, Version 2.0, Dated 18-Mar-2020; ISRCTN #: 85058577
REFNo: HS1822ES

Major Objective: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub- Saharan Africa
Specific Objectives
To evaluate an innovative and contemporary ART strategy in HIV-infected adolescents to provide choice for young people facing life-long treatment. Output from this RCT will provide evidence on efficacy, safety and acceptability of a novel treatment approach in HIV-infected adolescents in sub-Saharan Africa
To evaluate the virological efficacy, safety, acceptability and Quality of Life of DTG-based Short-cycle Therapy with weekends off compared with Continuous Therapy with a DTG- based ART regimen
To optimize treatment for HIV-infected adolescents in sub-Saharan Africa

Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Clinical Trial Non-degree Award
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