Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ninsiima Lesley Rose
ID:
BAT ECOLOGY AND SOCIAL EPIDEMIOLOGY OF FILOVIRIDAE HAEMORRAGIC FEVERS IN UGANDA
REFNo: HS3297ES

To predict the probability of spillover of filoviruses using a new time nonhomogeneous stochastic process at different seasons of the year in Albertine region. ,To determine the presence of filoviruses among selected bat roosting sites in the Rwenzori region. ,To explore anthropogenic drivers of spillover events from Ebola virus diseases in Mubende and Kassanda districts. ,To assess the knowledge, perception, and exposure towards bats by people living near bat roosting sites leading to spillover in Bundibugyo district. ,To evaluate the information on the relationship between bat behavior and distribution leading to spillover events of filoviruses. ,The main objective is to assess the relationship aspects of bat ecology and social epidemiology of filoviridae haemorragic fevers in Uganda.,
Uganda 2023-12-21 10:39:09 2026-12-21 Medical and Health Sciences Non-Clinical Trial Degree Award
John Ekure
ID:
PATIENT OUTCOMES AFTER SURGICAL REPAIR OF ACROMIOCLAVICULAR JOINT USING CERCLAGE-WIRE FIGURE OF ‘8’ TECHNIQUE AT KUMI ORTHOPAEDIC CENTER; A RETROSPECTIVE CONSECUTIVE CASE SERIES
REFNo: HS3450ES

To assess the quality of life of the patients after ACJ repair using the cerclage wire figure of ‘8’ technique at Kumi orthopaedic center.,To assess the long term outcomes of patients after ACJ repair using the cerclage wire figure of ‘8’ technique at Kumi orthopaedic center,To assess patient outcomes and quality of life following ACJ repair with cerclage wire figure of ‘8’ technique at Kumi orthopaedic center,
Uganda 2023-12-21 10:37:24 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kabugo
ID: UNCST-2019-R000502
Hospital to Home (H2H) programme for high-risk infants: Preparing for scale in a public facility setting
REFNo: HS3432ES

To evaluate the feasibility and fidelity of the H2H programme in a public government facility. To investigate the potential for scalability of the adapted H2H Public programme in a public government setting.
Uganda 2023-12-21 10:36:36 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Ssegawa
ID:
The Diversity and Distribution of macrophytes in selected wetlands in the Lake Victoria Basin
REFNo: NS656ES

This study aims to make an inventory of wetland vegetation types of the Victoria Lake Belt. These areas are densely populated and the various pressures on the ecosystem will be recorded. Wetlands will be selected on the basis of their size and variability and preference will be given to wetlands with strong environmental gradients within them and a large variation of wetland types. The objective is to describe as much as possible the full spectrum of wetland vegetation types that are found within the region, describe the vegetation and their ecology and draft a strategic conservation plan for wetlands in this region.
Uganda 2023-12-21 10:21:55 2026-12-21 Natural Sciences Non-Clinical Trial Non-degree Award
Emmanuel Kisaame Keith
ID:
Effectiveness of Privately Managed Cash Transfers in Africa: The case of Uganda and Tanzania
REFNo: SS2116ES

Understand the short- and long-term impact of privately managed cash transfer programmes on inclusive economic growth in Uganda.,Examine the cost-effectiveness of privately managed cash transfers are in Uganda. ,Understand the state-society relations inspired by privately managed cash transfers in Uganda. ,Examine the effectiveness of the selection criteria for recipients among privately managed cash transfers in Uganda.,The overall objective of the project is to investigate whether and to what extent privately managed cash transfers are politicized by ruling elites and how this affects inclusive sustainable growth and state-society relations.,
Uganda 2023-12-21 10:21:02 2026-12-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy Opobo
ID: UNCST-2023-R006042
ENGAGED SCHOLARSHIP AS A MEANS TO SUSTAINABLY SOCIAL PROBLEMS: A CASE OF CHILD WELL-BEING IN GULU DISTRICT.
REFNo: SS2109ES

i. To explore for the suitability of engaged social work scholarship in addressing Child wellbeing concerns in Uganda’s marginal communities;
ii. To examine challenges and constraints in the application of engaged scholarship in designing and implementation interventions to sustainably address Child wellbeing concerns in Uganda;
iii. To examine opportunities for sustainable collaboration between the social work scholars, local government and social development actors in designing and implementation of interventions that sustainably address Child wellbeing concerns.

Uganda 2023-12-21 10:19:52 2026-12-21 Social Science and Humanities Non-Clinical Trial Degree Award
Creed  Irena Frances
ID:
Assessing cyanobacteria risks in Ugandan crater lakes through historical and contemporary perspectives
REFNo: NS679ES

- To reconstruct phycological time series to establish baseline conditions in the Crater Lake district of western Uganda and determine if (and when) cyanobacteria abundance and toxin-producing potential have changed over time. (Paleolimnology)

2) To examine the historical and societal influence of local (e.g., land use) and regional (e.g., climate) stressors on regulating cyanobacteria abundance and toxin-producing potential. (Paleolimnology)

3) To characterize spatiotemporal variation in cyanobacteria risks and determine the societal influences of local (e.g., land use) and regional (e.g., climate) stressors on regulating cyanobacteria abundance and toxin-producing potential. (Field Survey)

Canada 2023-12-21 10:18:34 2026-12-21 Natural Sciences Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
Longitudinal Neurodevelopment in a Sub-Saharan Africa Cohort (LONISAC study)
REFNo: HS3405ES

1. To describe brain development (white matter volume, grey matter volume and total brain
volume) trajectories as measured by MRI among typical children from birth to 5 years of age
2. To describe patterns of motor, cognitive, language and social-emotional development among
typical children from birth to 5 years of age
3. To describe patterns of physical growth among typical children from birth to 5 years of age
4. To explore prenatal and postnatal factors associated brain and neurocognitive development
(school readiness) at 5 years of age
5. To describe the association between total white matter volume and the global scale for early
development (GSED) scores
Uganda 2023-12-21 10:17:30 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Namakula
ID: UNCST-2022-R006923
Burden of antibiotic use among outpatients at Mulago National Referral Hospital, Uganda.
REFNo: HS3440ES

1. To determine the prevalence of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
2. To determine the appropriateness of antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda.
3. To determine the factors associated with antibiotic prescription among outpatients at Mulago National Referral Hospital, Uganda

Uganda 2023-12-21 10:16:27 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Realist Evaluation and Learning in a Multi-country Medical OXYgen Program (REAL-MOXY)
REFNo: HS3444ES

To understand the perspectives of a) patients/caregivers, b) healthcare workers, managers and biomedical engineers/technicians.,To examine how pulse oximetry and oxygen are used by nurses and medical officers, why, and how this impacts on patient care.,To follow patient journeys from arrival through the first 4 hours of care, to understand the sequence of care for acutely unwell children, including how pulse oximetry and oxygen are integrated with other aspects of emergency care.,To map care pathways (as they are intended) for children (<15 years) with four hypothetical clinical scenarios in each participating facility. ,To identify facilities with high and low functioning oxygen systems, based on current pulse oximetry and oxygen-related clinical practices and facility oxygen readiness.,To understand how oxygen and pulse oximetry are used (or not used) at a facility level, and to identify opportunities for strengthening oxygen systems for beneficiaries, users and managers. ,
Uganda 2023-12-21 10:12:51 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Nanyonjo Gawaya
ID: UNCST-2022-R005857
CELEBRATE: Acceptability and Feasibility of bnAbs for Infant HIV Prevention in South Africa and Uganda
REFNo: HS3466ES

1. Understand acceptability and preferences for product attributes and identify factors that influence the adoption of bnAb prevention products for post-natal prophylaxis among healthcare providers, mothers, family members, and community stakeholders.
2. Identify special considerations for administering bnAbs to infants in the post-natal period, including challenges, perceived benefits, and feasibility considerations.
3. Understand key health system and programmatic perspectives including challenges and feasibility of introducing bnAb for post-natal prophylaxis among health service providers and policy makers.

Uganda 2023-12-19 11:29:43 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian Muwonge
ID:
Piloting a Digital One Health platform for AMR surveillance
REFNo: HS3391ES

1.Testing the utility of our mobile phone application prototype for harmonizing metadata capture 2. Piloting the use of long-read sequencing of routinely cultured pathogens (Escherichia coli and Klebsiella spp.) 3. Developing a portable and integrated data workflow to feed into our prototype data sharing and analysis web portal 4.Supporting local capacity building through training seminars on long read sequencing and data analysis. The output of this project will allow us to demonstrate and evaluate the feasibility and challenges of integrating One Health as a shared resource
Uganda 2023-12-19 11:27:37 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dennis Ssesanga Ernest
ID: UNCST-2023-R008022
EFFECT OF MHEALTH COMMUNICATION ON STIGMA AND RETENTION IN CARE AMONG YOUTH LIVING WITH HIV AND LINKED TO CARE IN UGANDA.
REFNo: SS2215ES

1. To explore the effect of mhealth communication on stigma among youth living with HIV and linked to care in Uganda.
2. To systematically develop and evaluate an mHealth intervention on stigma and retention in care among youth living with HIV and linked to care in Uganda.
3. To investigate the determinants of stigma and retention in care among youth living with HIV and linked to care in Uganda.
4. To determine the effect of mhealth communication on retention in care among youth living with HIV and linked to care in Uganda.
Uganda 2023-12-19 11:26:33 2026-12-19 Social Science and Humanities Clinical Trial Degree Award
Beatrice Francis Robinah Nassanga
ID:
Factors associated with immunogenicity of tuberculosis vaccines in Ugandan adolescents
REFNo: HS3343ES

1. To determine the impact of baseline infectious exposures and sociodemographic factors on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 2. To characterise the baseline innate immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents 3. To characterise the baseline T and B cell immune microenvironment and its impact on the immunogenicity of BCG revaccination and of candidate TB vaccine “ChAdOx1-85A prime – MVA85A boost” in Ugandan adolescents
Uganda 2023-12-19 11:23:12 2026-12-19 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Attitudes and Beliefs Around Smoking Behaviors and Smoking Cessation Among People Living with HIV and Healthcare Providers in Uganda
REFNo: HS3301ES

to understand smoking behaviors and attitudes and beliefs around smoking cessation among PLWH, to mitigate risk factors for cancer in this population. We also seek to explore underlying factors, and perceived facilitators and barriers of smoking cessation among patients and healthcare providers to promote the development of effective smoking cessation interventions for PLWH.
Uganda 2023-12-19 11:21:20 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wabwire  Oduke Julius
ID:
Inclusion in Universal Primary Education and Outcomes of Learning Disabilities in Wakiso District.
REFNo: SS1957ES

1) To find out the extent to which the mechanism in school climate foster inclusion in UPE and their effect on education outcomes of learning disabilities. ,The purpose of this study is to examine the inclusion mechanisms of school climate and teachers inclusive efficacy using the ecological systems model integrated with the social cognitive theory as determinants of educational outcomes for children with learning disabilities under the universal primary education system.,
Uganda 2023-12-19 11:19:22 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Winifred Kayizzi Nimukunda
ID:
University governance and research performance in selected public universities in Uganda
REFNo: SS1952ES

The research is to investigate the relationship between university governance and research performance of public universities in Uganda,To examine the impact of participation by university stakeholders in governance decision making processes on research performance of public universities in Uganda.,To investigate the academic governance practices impact on research performance of public universities in Uganda.. ,To establish the effect of governance architecture on research performance of public universities.,
Uganda 2023-12-19 11:16:13 2026-12-19 Social Science and Humanities Non-Clinical Trial Degree Award
Damalie Nakanjako
ID: UNCST-2019-R000383
Training needs assessment for Schistosomiasis research training at academic and research institutions in Uganda
REFNo: HS3446ES

To identify the research training resources, faculty development, scientific environment contributions and administrative processes needed to undertake a research-training program focused on schistosomiasis.,To assess the existing research and research training capacity for schistosomiasis at Makerere University and collaborating institutions (other Uganda universities, Uganda Virus Research Institute and the Ministry of Health vector control division).,The general aim of this project is to assess existing research and research training capacity for schistosomiasis at Uganda institutions,
Uganda 2023-12-19 11:13:21 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Namusobya Sarah
ID:
Harnessing machine learning to predict risk of treatment interruption among people living with HIV in Uganda
REFNo: HS3411ES

2. To validate/test the model to assess its performance in predicting risk of TI among PLWH in Uganda,1. To train the model in predicting risk of TI among PLWH in Uganda,To use available Big Data at TASO Uganda to build a ML model that can predict risk of TI among PLWH in Uganda,
Uganda 2023-12-19 11:11:37 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Ocan
ID:
An analysis of Ugandan Malaria Epidemic Situation and Real-world Effectiveness of Fludora Fusion in Malaria vector control
REFNo: HS3416ES

4. To explore facilitators, experiences of individuals in households and barriers to malaria mosquito vector control using Fludora Fusion in Yumbe district, Westnile region, Uganda. ,3. To evaluate the real-world effectiveness of indoor residual spraying using Fludora Fusion in Uganda using a prospective design. ,2. To determine malaria burden in public and private health facilities in Fludora Fusion exposed (Yumbe district) and non-exposed (Soroti district) settings in Uganda using a retrospective design.,1. To establish through a systematic review and meta-analysis the efficacy of Fludora Fusion and other chemical compounds used in indoor residual spraying for malaria mosquito vector control in sub-Saharan Africa.,To investigate the efficacy of Fludora Fusion against primary malaria vectors, community experiences, and practices regarding indoor residual spraying and the implications on malaria burden in selected districts in Westnile region, Uganda. ,
Uganda 2023-12-19 11:10:14 2026-12-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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