Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ezekiel Mupere
ID: UNCST-2021-R011972
Adaptive immunity to Mtb-infection and TB disease among young Ugandan children”
REFNo: HS1870ES

1.To recruit Ugandan children 5 years and younger (< 60 months), with and without perinatal HIV-exposure and/or infection, who are household contacts of an adult with confirmed TB disease
2.To identify immunologic phenotypes that correlate with TB disease, versus remaining asymptomatic following TB household contact, in young children with and without perinatal HIV-exposure and/or infection
3.To determine if MTB-specific T cell and/or antibody profiles can be used to distinguish TB disease from asymptomatic MTB infection, in young children with and without perinatal HIV-exposure and/or infection
4.To determine how perinatal HIV exposure/infection alters MTB-specific adaptive immune profiles

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Muhindo
ID:
Tackling coronavirus disease-2019 Vaccine Hesitancy among People Living with HIV in Kampala, Uganda
REFNo: HS1902ES

To describe the prevalence and factors associated with COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
2. To explore the drivers of COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
3. To develop and pilot educational materials to promote COVID-19 vaccine uptake among adult PLHIV in Kampala, Uganda

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
Voluntary stool collection for optimizing laboratory techniques at the MRC/UVRI and LSHTM Uganda Research Unit
REFNo: HS1910ES

Objectives of the research project:
• To obtain Schistosoma mansoni ova for training and optimisation of the process of miracidia hatching and snail infection
• To obtain S. mansoni ova for training and optimisation of the process of sex determination of cercariae
• To develop materials such as S. mansoni DNA that can be used as reagents and/or positive controls.
• To make available S. mansoni materials for use in the routine evaluation of proficiency of assays and for the testing of reagents and new assay kits

UK 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE MBABAZI -MPYANGU
ID:
Thriving Together: Creating Social Support Groups for the Reintegration and Empowerment of Formerly Abducted Women in Northern Uganda
REFNo: SS965ES

1) Assess the current social, economic and psychological status of formerly abducted women in Northern Uganda as compared to never abducted comparable women
2) Scientifically test the effectiveness of women’s support groups in facilitating the reintegration of formerly abducted women, raising their aspirations, creating economic opportunities and increasing their overall well-being.
Uganda 2021-12-06 2024-12-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
DEVELOPMENT OF AFFORDABLE, EASY TO USE, AND RAPID POINT OF CARE DIAGNOSTIC TESTING PLATFORMS FOR COVID-19 SUITING REMOTE SETTINGS OF SUB-SAHARAN AFRICA.
REFNo: HS1648ES

1.To optimize and validate reagents (recombinant peptides, monoclonal and polyclonal antibodies)’s performance towards capture of SARS- CoV 2 virus antigen and host specific antibodies
2.To develop prototypes of lateral flow immunochromatography test (LFT) and tube-agglutination test platforms for COVID19 testing
3.To perform In-dependent validation of the developed test platforms.


Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."