Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Twalib Aliku Olega
ID: UNCST-2019-R000474
LEVERAGING RHEUMATIC HEART DISEASE SCREENING PROGRAMS TO IMPROVE OUTCOMES FOR CONGENITAL HEART DISEASE IN NORTHERN UGANDA
REFNo: HS5492ES

1) To improve the quality of life for families living with CHD in Uganda. Our overarching hypothesis is that building a system centered on the needs of patients and providers at the community level will improve care and quality of life for many while simultaneously building the case to invest in more resource intensive tertiary infrastructure.
Our project leverages our team’s expertise and established government and community collaborations to improve CHD care by accomplishing following specific aim as the first step to delivering and testing an evidence-based primary Health Center (HC) driven program - Congenital Heart Interventions for Primary care Systems (CHIPS) - to care for children with CHD incidentally identified through RHD screening.

2) Identify needs, gaps, and capacities in CHD care to co-design the CHIPS technical package with end-users (patients, caregivers and community providers) by collecting quantitative and qualitative data on current care, care needs, access, and affordability and perspectives on proposed components of CHIPS to co-design content and delivery.
Uganda 2025-02-20 17:26:59 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
Developing and Testing a Package of Interventions to Improve Patient Engagement in Rheumatic Heart Disease Care in Northern Uganda: A mixed Methods Study
REFNo: HS5605ES

Objective 1: To describe the treatment cascade of RHD care in Kitgum district and determine the associated factors.
Objective 2: To explore the barriers and facilitators of patient engagement in RHD care in Kitgum district.
Objective 3: To co-develop a package of interventions to improve patient engagement in RHD care.
Objective 4: To evaluate the effectiveness of a package of interventions to improve patient engagement in RHD care in Kitgum district.
Uganda 2025-02-20 17:21:09 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
WOMEN’S INCLUSIVE SERVICES FOR HEALTH ACCESS TO QUALITY HEALTHCARE FOR PREGNANT AND BREASTFEEDING WOMEN WITH DISABILITIES IN UGANDA
REFNo: HS5552ES

1. To identify and understand the existing disparities in HIV and maternal healthcare services affecting pregnant and breastfeeding mothers with disabilities
2. To elicit the perceptions and experiences of people with disabilities that affect their health-seeking behavior, especially for HIV, maternal, and reproductive health services.
3. To promote awareness and education among women about their healthcare rights and available services.
4. To collaborate with relevant stakeholders, including healthcare providers, policymakers, and community organizations, to implement sustainable changes.


UK 2025-02-20 17:18:32 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PRECIOUS NATUHWERA
ID: UNCST-2024-R003154
Clinical presentations, prevalence and factors associated with cranial hemorrhages among neonates admitted at Mbarara Regional Referral Hospital
REFNo: HS5377ES

General objective
To determine the clinical presentations, prevalence and factors associated with cranial haemorrhages among neonates admitted at Mbarara Regional Referral Hospital.
Specific objectives
1.To determine the prevalence of extracranial and intracranial haemorrhages among neonates admitted to the NICU of Mbarara RRH.
2.To describe the clinical profiles of neonates with cranial haemorrhages admitted to the NICU at Mbarara RRH
3.To determine the factors associated with cranial haemorrhages among neonates admitted to the NICU at Mbarara RRH.

Uganda 2025-02-20 17:16:30 2028-02-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Ashirafu  kule masudi
ID: UNCST-2024-R004729
TEACHER’S COMMITMENT AND STUDENTS’ ACADEMIC PERFORMANCE IN PUBLIC SECONDARY SCHOOLS IN KASESE DISTRICT, UGANDA
REFNo: SS3529ES

i. Examine the relationship between teachers’ job satisfaction and students’ academic performance in public secondary schools in Kasese District, Uganda.
ii. To determine the relationship between work environment and students’ academic performance in public secondary schools in Kasese District, Uganda.
iii. Establish the relationship between teacher’s level of professional training and development on students’ academic performance in public secondary schools in Kasese District, Uganda
iv. Evaluate the relationship between school leadership and students’ academic performance in public secondary schools in Kasese District, Uganda.

Uganda 2025-02-20 17:15:03 2028-02-20 Social Science and Humanities Non-Clinical Trial Degree Award
Naomi Nsubuga
ID: UNCST-2024-R003628
School Eye Health Rapid Assessment (SEHRA) to review the policy environment and determine the magnitude and patterns of eye health conditions among public primary school children in select regions in Uganda.
REFNo: HS4803ES

2. To determine the magnitude, characteristics and any patterns of eye health conditions among children in selected public primary schools across the six selected regions in Uganda.,1. To conduct a rapid review of the policy, strategy, institutional and service delivery environment for a school eye health programme in Uganda. ,To review the policy environment on school eye health and determine the magnitude and patterns of eye health conditions among public primary school children in selected regions in Uganda,
Uganda 2025-02-20 17:12:48 2028-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Byarugaba
ID: UNCST-2024-R004225
Midterm evaluation of Our Rights, Our Future PLUS (O3PLUS)
REFNo: SS2565ES

The evaluation objectives are to:
1. Ascertain the relevance, coherence, effectiveness, efficiency, and sustainability of the O3PLUS Project.
2. Assess progress against targets set at baseline, validate, and populate the results framework.
3. Identify opportunities, challenges, innovative practices, and lessons that will be useful for strengthening and enhancing the implementation of the remaining project period.
4. Provide conclusions and actionable recommendations to shape future programming and implementation of similar initiatives.

Uganda 2025-02-20 17:11:11 2028-02-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Muhumuza
ID: UNCST-2023-R008646
Improving Family Wellness for Couples in Central Uganda 2024-2029
REFNo: HS5523ES

The study aims are to:

(1) In a cluster randomised trial, compare the efficacy of the FH=FW intervention vs. a time/attention matched comparator intervention at increasing modern contraceptive use and reducing unintended pregnancy among couples with an unmet need for family planning through 24-months, and identify potential mediators of the intervention effect.

(2) Determine the intervention’s effect on, and determinants of, contraceptive continuation.

(3) Through a mixed-methods process evaluation, explore factors affecting the implementation of the intervention in order to improve feasibility, acceptability, and the likelihood of future adoption and sustainment
Uganda 2025-02-20 17:09:28 2028-02-20 Medical and Health Sciences Clinical Trial Non-degree Award
Sally Andersson Lova Sofia
ID: UNCST-2024-R002577
Agrarian Governmentality & Interacting Policies: Young Farmers' Subjectivity and Agency in the Gulu District, Uganda
REFNo: SS3634ES

To gain knowledge on how young farmers in Uganda socially navigate the subjectivities constructed in the policies, using their agency to internalise, adopt, or adapt them, or to create counter-conduct subjectivities. ,To understand how young farmers experience challenges and opportunities in farming, and how they view the solutions to these challenges offered in various interacting agrarian policies. ,To explore the various subjectivities for young farmers found within problem representations in the governmental policies, illuminating possible synergies and discords between policies attempting to solve different challenges, as subjectivities offer different possible courses of actions to young farmers.,To explore how young farmers in Uganda interact with synergies and discords in governmental policy responses to climate change and the associated challenges and opportunities facing young farmers. ,
Sweden 2025-02-14 17:37:37 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
ConfiSign HIV Self-Test: Evaluation of Clinical Performance and Usability in the hands of untrained users.
REFNo: HS5545ES

The objective of this study is to evaluate the clinical performance and the usability of the ConfiSign HIV Self-Test in the hands of untrained users from a low prevalence HIV region and having no experience in HIV self-testing (HIVST).
The following specific studies will be conducted:
Part 1: Results Interpretation Study
Part 2: Observed untrained user study

Uganda 2025-02-14 17:33:35 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Asiimwe
ID: UNCST-2019-R000059
Clinical Spectrum and Societal Impact of Cognitive Impairment, Alzheimer’s and Related Dementias Among People with HIV in Uganda
REFNo: HS5493ES

1. Determine the prevalence and classification of MCI/ADRDs (1A) and compare trajectories of cognitive performance (1B) between older PWH in Uganda and demographically similar HIV-negative individuals.
2. Identify pathophysiologic contributors to MCI/ADRDs in older adults in Uganda by performing deep phenotyping with novel plasma biomarkers and neuroimaging.
3.Discover and validate novel, multilevel mechanistic models of MCI/ADRDs among older PWH by employing ML methods.
Uganda 2025-02-14 17:30:42 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laura Keihäs Anna Maria
ID: UNCST-2024-R015717
Exploring the Role of Expressive Arts in the Emancipation and Well-being of Girls. Case Study from Kabale, Uganda
REFNo: SS3612ES

- to gather new information on the relationship between expressive arts, emancipation and well-being of youth, especially Ugandan girls in vulnerable life situations
- to gain a better understanding of the Ugandan and African approaches to well-being and emancipation
- to get new decolonial, Ugandan and African perspectives on global youth research and critical social pedagogy
The study aims to contribute to planetary social pedagogy and global youth research. It will provide new insights and African perspectives on the potential of creative expression to support youth well-being in Uganda and beyond.
Finland 2025-02-14 17:24:47 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel Mugisha
ID: UNCST-2024-R002496
VICARIOUS TRAUMA AND JOB PERFORMANCE OF WORKERS IN SELECTED HUMANITARIAN ORGANIZATIONS IN SOUTH WESTERN UGANDA
REFNo: SS3592ES

1. To examine the effects of emotional distress on job performance of workers in humanitarian
organizations of Southwest Uganda.
2. To explore effects intrusive thoughts on job performance of workers within humanitarian
organizations of Southwest Uganda
3. To investigate the moderating effects of social support on job performance of workers in
humanitarian organizations of Southwest Uganda.
4. To analyze the moderating effects of self-esteem and gender on the relationship between vicarious
trauma and job performance of workers in humanitarian organizations of Southwest Uganda.
5. To establish the relationship between vicarious trauma and job performance of workers in
humanitarian organizations of Southwestern Uganda
Uganda 2025-02-14 17:21:36 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Mark Jordans
ID: UNCST-2020-R014861
POPULATION-LEVEL EVALUATION OF A MENTAL HEALTH CARE PACKAGE FOR CHILDREN IN SELECTED REFUGEE SETTLEMENTS IN UGANDA (PAMOJA TUNAWEZA): A CLUSTER RANDOMIZED CONTROLLED TRIAL (cRCT)
REFNo: SS3571ES

To evaluate the impact of a mental health care system on improving population level mental health of children in refugee settlements, with the following guiding research questions and hypotheses:
Netherlands 2025-02-14 16:25:24 2028-02-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Diana Namuddu
ID: UNCST-2024-R003660
Knowledge, attitudes, and practices of healthcare workers regarding the use of standard malaria management guidelines
REFNo: HS5458ES

1) To explore healthcare workers’ knowledge, attitudes, and practices regarding malaria management guidelines in Adjumani and Kitgum districts. 2) To investigate the behavioural and social factors influencing malaria case management among healthcare workers in Adjumani and Kitgum districts. 3) To evaluate healthcare workers' willingness to recommend the malaria vaccine for preventing malaria in children once it becomes available in Adjumani and Kitgum districts. 4) To identify facilitators and barriers affecting the adoption of malaria management guidelines among health workers in Adjumani and Kitgum districts
Uganda 2025-02-14 16:17:09 2028-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nerima
ID: UNCST-2024-R015736
A QUALITATIVE STUDY EXPLORING FACTORS AFFECTING MULTIPLE MICRONUTRIENT SUPPLEMENTS (MMS) ADHERENCE AMONG PREGNANT WOMEN IN SOUTH CENTRAL AND BUSOGA REGION IN EASTERN UGANDA.
REFNo: HS5478ES

4. To make recommendations to public health stakeholders and decision-makers on strategies to enhance the uptake of MMS among pregnancy women in Uganda in the context of south and central Uganda.,3. Employ thematic analysis to examine healthcare providers\' perspectives on barriers and facilitators to pregnant women\'s adherence to MMS, as well as their insights into the strengths and weaknesses of existing strategies aimed at improving adherence.,2. Explore, through semi-structured interviews, the perspectives of healthcare providers in Uganda on factors influencing pregnant women\'s adherence to MMS, including their insights into the effectiveness and compliance of existing strategies, policies, interventions, and approaches.,1. 1. To explore existing knowledge on factors influencing pregnant women\'s adherence to multiple micronutrient supplementation.,
Uganda 2025-02-14 16:15:37 2028-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
kamya Damiano Damiano
ID: UNCST-2024-R002433
"REMOTELY TEACHING CHILDREN WITH NEURODEVELOPMENTAL PROBLEMS: EXPERIENCES OF TEACHERS, SCHOOL MANAGERS AND PARENTS IN CENTRAL UGANDA"
REFNo: SS3556ES

Purpose of the Study.
The purpose of this study is to explore teachers’, school managers’ and parents’ experiences in remotely teaching children with neurodevelopmental problems in Central Uganda.
Specific Objectives
1. To examine,
a) teachers’
b) school managers’
c) and parents’ experiences on remotely taught children with neurodevelopmental problems.
2. To evaluate the opportunities of remotely teaching children with neurodevelopmental problems.
3. To examine the challenges faced by;
a) teachers
b) school managers
c) parents while remotely teaching children with neurodevelopmental problems.
4. To examine the interventions that can enhance experiences of remote teaching of children with neurodevelopmental problems.

Uganda 2025-02-14 16:10:11 2028-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
Gal Badihi
ID: UNCST-2024-R016596
Sociality and communication dynamics in grey-cheeked mangabeys (Lophocebus albigena) in the Bugoma Forest Reserve, Uganda
REFNo: NS911ES

The project aims to describe the communicative repertoire and social function of communication in grey-cheeked mangabeys
UK 2025-02-14 16:05:25 2028-02-14 Natural Sciences Non-Clinical Trial Non-degree Award
SAMSON OKUNG
ID: UNCST-2024-R003644
COMPETENCE-BASED TRAINING OF AUTOMOTIVE STUDENTS IN TECHNICAL TRAINING INSTITUTES IN THE EASTERN REGION OF UGANDA
REFNo: SIR434ES

(iv) To assess the financial adequacy on competence-based training of Automotive students in Uganda. , (iii) To establish the influence of human resource capacity on competence-based training of Automotive students in Uganda. ,(ii) To examine infrastructure relevance on competence-based training of Automotive students in Uganda.,(i) To determine the influence of instructional resources on competence-based training of Automotive students in Uganda.,The main objective is to investigate the effectiveness of competence-based training of automotive students in technical training institutes in the eastern region of Uganda.,
Uganda 2025-02-14 15:56:43 2028-02-14 Engineering and Technology Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Evaluation of the Safety, Efficacy and Stability of SangaSupa®-30% Emulsifiable Concentrate [EC]: A Randomised Single-Blinded Positive Controlled Multi-Site Acaricide Field Trial
REFNo: NS910ES

General objectives
To determine the efficacy, safety, and stability of SangaSupa® (Sanga Vet. Chem. Ltd, Kampala Industrial Park, Namanve ) when applied onto cattle by hand spraying and plunge dipping for tick control.
Specific objectives
The specific objectives of this acaricide field trial will to determine;-
i. efficacy of SangaSupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
ii. safety of Sangasupa® when applied onto cattle by hand spraying and plunge dipping for tick control.
iii. Stability of Sangasupa® when applied onto cattle by plunge dipping for tick control.
Uganda 2025-02-14 15:53:01 2028-02-14 Natural Sciences Clinical Trial Non-degree Award
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