Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Building the Foundation for Effective Sore Throat Treatment in Uganda.
REFNo: HS3473ES

Objective 1: Co-design a sore throat treatment program model using a community based participatory research approach to ensure a culturally and contextually appropriate and effective strategy for primary prevention of RHD.

Objective 2: Describe the current health seeking behavior of children who have a sore throat, including barriers and facilitators to seeking care within the formal healthcare system.

Objective 3: Describe the current approach by health care workers to a child presenting with sore throat, including barriers and facilitators to guideline-based care for children with sore throats.
Uganda 2024-01-08 13:11:15 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daudi Jjingo
ID:
AI for Health Equity: Transforming Pandemic Preparedness in Uganda (HEAL)
REFNo: HS3524ES

Primary objective: To leverage advanced Large Language Models (LLMs) like GPT-4 to convert the Uganda Ministry of Health pandemic preparedness guidelines and the National Action Plan for Health Security (NAPHS) into an interactive, conversation-based tool, accessible in a native African language. Secondary objective: To validate the effectiveness of the dynamic AI platform encompassing language adaptation, user satisfaction and perception, seamless implementation in clinical settings, and tangible impact on clinical decision-making by conducting focused field testing involving a group of 60 healthcare professionals.
Uganda 2024-01-08 13:08:26 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
ADAPTATION, FEASIBILITY AND ACCEPTABILITY OF CAREGIVER PEER-SUPPORTER FACILITATED HIV STATUS DISCLOSURE INTEVERNTION FOR CHILDREN IN EASTERN UGANDA – A TASK SHIFTING MODEL
REFNo: HS3547ES

To assess the feasibility and acceptability of the CPS facilitated disclosure intervention ,1. To culturally adapt a clinic-based pediatric HIV status disclosure intervention into CPS facilitated HIV status disclosure intervention among CLHIV and their caregivers in Uganda,To culturally adapt and assess the feasibility and acceptability of a CPS-facilitated HIV status disclosure intervention among caregivers of CLHIV at Jinja Regional Referral Hospital in Eastern Uganda. ,
Uganda 2024-01-08 13:07:36 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
Achieving HIV viral suppression in refugee settlements in Uganda with Head StART: a cluster randomized trial evaluating the effectiveness of community ART delivery for people newly diagnosed with HIV
REFNo: HS2935ES

To estimate the programmatic cost and budget impact of implementing the Head StART intervention in refugee settlements in Uganda. ,To assess Head StART implementation across refugee settlement sites to understand the impact of contextual factors on study outcomes. ,To evaluate the effectiveness of “Head StART,” the expansion of community ART delivery to people newly diagnosed with HIV, in achieving HIV viral suppression in refugee settlements in Uganda. ,The primary objective of this research is to evaluate the effectiveness of expanding community ART delivery to clients newly diagnosed with HIV.,
Uganda 2024-01-05 9:11:58 2027-01-05 Medical and Health Sciences Clinical Trial Non-degree Award
Kiggundu Nicholas
ID: UNCST-2023-R006508
Hyperlocal Elicitation and Understanding of Risks to Stability in Complex Systems
REFNo: A369ES

Develop more effective models to predict agro-pastoralist and pastoralist livelihood behaviors,- Expanded use of machine learning and internet-based texts to make predictions and using those in conjunction with field data from surveys and interviews.,Understand the impact of mining on food security and local food systems in Karamoja Sub region.,
Uganda 2024-01-05 9:09:35 2027-01-05 Agricultural Sciences Non-Clinical Trial Non-degree Award
Bob Denis Odongo
ID:
Access to livelihood assets, adaptive strategies and livelihood outcomes among refugees in Bidibidi settlement-Uganda.
REFNo: SS2114ES

Objectives of the study The main object of this study is to investigate factors that influence refugees’ access to sustainable livelihoods in Bidibidi settlement in Uganda. Specific Objective Stemming from the aim of the study as outlined above, this study sought to achieve the following specific and subsidiary objectives. 1) To explore factors that influence access and utilisation of livelihood assets among refugees in Uganda 2) To assess livelihood barriers and enablers for refugees in achieving sustainable livelihoods outcomes. 3) To examine the key adaptation and coping strategies that facilitates refugees’ achievement of livelihood outcomes. 4) To develop a modal on sustainable livelihood by the end of the study that will guide refugee programming.
Uganda 2024-01-05 9:07:36 2027-01-05 Social Science and Humanities Non-Clinical Trial Degree Award
Michael OCAIDO
ID:
Optimisation of integrated control of ticks and tsetse flies in mixed game and livestock interfaces in Uganda
REFNo: A365ES

The aim of the project is to introduce and demonstrate the profitability of community participation in strategic control of tsetse flies and ticks by restrictive spraying of vector predilection sites on cattle using dual purpose deltamethrin products in Mixed Game Livestock Interfaces
Uganda 2024-01-05 9:04:52 2027-01-05 Agricultural Sciences Non-Clinical Trial Non-degree Award
Doreen Nampamya
ID:
Impact of Robusta coffee systems diversification on mycorrhizal diversity & traits: Implication for soil fertility and Carbon sequestration in Uganda
REFNo: A328ES

1. To determine the ecological distribution of soil mycorrhizal fungal community in Ugandan Robusta coffee systems.
2. To determine the effect of Robusta coffee system diversification on soil mycorrhizal diversity and structure across a climatic gradient
3. To assess the effects of mycorrhizal traits on soil productivity and carbon sequestration in three different climatic zones of Robusta coffee systems of Uganda
4. To determine the effect of mycorrhiza association on rooting ability of Robusta coffee seedlings

Uganda 2024-01-05 9:04:03 2027-01-05 Agricultural Sciences Non-Clinical Trial Degree Award
PATRICK MUSINGUZI
ID: UNCST-2023-R007731
UTILITY, ACCEPTABILITY AND APPLICABILITY OF A NUCLEIC ACID AMPLIFICATION TEST (NAAT) IN COMPARISON WITH SYNDROMIC APPROACH IN THE MANAGEMENT OF SEXUALLY TRANSMITTED DISEASES AT MULAGO NATIONAL REFERRAL HOSPITAL IN UGANDA.
REFNo: HS3100ES

To estimate the actual relative prevalence of causative agents of STDs in our study setting.,To evaluate the acceptability of the NAAT.,To assess the degree of concordance between actual pathogens diagnosed through the molecular test and the presumed pathogens indicated by the syndromic approach.,To evaluate whether the use of NAAT for the management of STDs improves clinical outcome and microbiological cure compared with the syndromic approach.,To evaluate whether microbiological diagnosis using NAAT improves appropriateness of therapy of STDs (as a measure of clinical usefulness) in comparison with the syndromic approach without or with limited laboratory tests currently in use.,
Uganda 2024-01-05 9:01:56 2027-01-05 Medical and Health Sciences Clinical Trial Non-degree Award
Juliet Kyayesimira
ID:
DEVELOPING ECO-FRIENDLY PACKAGING FROM CASSAVA WASTE IN EAST AFRICA
REFNo: NS681ES

To develop a financial model and business case for the eco-friendly bio-degradable packaging material from cassava waste.,To develop sample packaging prototypes for food and other packaging purposes,To determine the quality of laboratory scale sheets of cassava waste.,To establish a baseline situation for commercial bio-waste packaging production through identification and mapping out key resources and value chain actors.,To develop, test, and commercialize biodegradable and environmentally-friendly packaging solutions from cassava waste for the East African Market.,
Uganda 2024-01-05 8:56:15 2027-01-05 Natural Sciences Non-Clinical Trial Non-degree Award
Josephine Namitala
ID:
Exploring the informal uses of mobile phones by health workers and managers in Uganda: A qualitative study
REFNo: HS3483ES

Primary project goals
a) To explore how healthcare workers and managers adapt and use mobile phone devices in
their everyday work and the impacts of these informal strategies on their experiences of work, on service delivery and on social equity.
b) To understand the implications of informal mobile phone use for clinical and health systems governance and participation in decision making.
c) To develop insights on how innovative, informal uses of digital communication tools can inform the future development and implementation of digital interventions for health systems strengthening and how an innovation ecosystem can be fostered.

Secondary project goals
d) To address key empirical and theoretical gaps in implementation science on how informal innovations become embedded into routine practice in resource-constrained health systems
e) To generate understanding of how co-production approaches can enhance user involvement in research, and facilitate knowledge translation and uptake of health care innovations


Uganda 2024-01-05 8:53:37 2027-01-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Alice Gitta Kutyamukama
ID:
Antenatal Mental Health Information Provision in China Uganda Friendship Hospital Naguru, Uganda
REFNo: SS2180ES

i.To examine the antenatal mental health information needs of pregnant women at CUFHN.

ii. To establish antenatal mental health information services during antenatal care to pregnant women at CUFHN.

iii. To examine the level of access and utilization of antenatal mental health information provision by pregnant women at CUFHN.

iv. To examine the barriers (if any) towards utilization of antenatal mental health information provided to pregnant women at CUFHN.

Uganda 2023-12-22 23:00:04 2026-12-22 Social Science and Humanities Non-Clinical Trial Degree Award
Isdore Guma Paterson
ID:
A Spatial System Dynamics Model to Support Decision-Making in Land-use Change Management: The Case of Mt. Elgon Region RefNo:UCUREC-2023-649
REFNo: SIR268ES

To validate the spatial system dynamics model for establishing model plausibility in enhancing land-use and land-cover change decisions. ,To design a spatial system dynamics model for quantifying data linked to decisions in land use resource management.,To design cause-effect relationships to appreciate the interconnectedness of the factors of land use and land-cover changes.,To investigate factors influencing spatial and temporal variations in land use and land cover. ,This research aims to develop a spatial system dynamics model to support decision-making in land use change management. ,
Uganda 2023-12-22 22:58:38 2026-12-22 Engineering and Technology Non-Clinical Trial Degree Award
Godfrey Barigye
ID:
Transition in Tradition: Indigenous Knowledge Systems for Sustainable Community Transformation and Development in Uganda: A case study of Greater Ankore RefNo: SS2031ES
REFNo: SS2224ES

1.To capture and document Banyankore indigenous knowledge systems.
2.To generate and share useful Banyankore indigenous knowledge systems.
To promote wider usage, application, preservation and establishment of a Center for Banyankore indigenous knowledge systems.
Uganda 2023-12-22 22:56:59 2026-12-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tyne  Williams Ashley
ID:
Local Conceptions of Child Agency in Post-Conflict Reintegration
REFNo: SS1756ES

The aim of the study is to contribute a normative understanding and conceptualisation of child agency that moves beyond traditional assumptions to recognise the saliency of cultural and local normative conceptualisations
To achieve this aim, the primary objective is to formulate a new normative framework and conceptualisation of child agency in post-conflict reintegration based on the findings drawn from fieldwork conducted in northern Uganda.

The specific objectives to achieve the main objective are as follows:

1. To explore the conceptual and academic foundations of the key concepts inherent within the study, namely ‘the child,’ childhood, child soldier, agency, and reintegration.

2. To utilise the case study of northern Uganda’s former child soldiers and their experiences during both formal reintegration processes and informal participatory avenues to critically examine the applicability of the concepts to the reality of what is taking place.

3. To engage directly with FCS and their communities to draw upon their perspectives, realities, and actions to comprehend the nature of child agency and participation within a post-conflict society.

4. To determine the causal implications of a conceptualisation of child agency towards the formulation of reintegration programmes targeting children, particularly in relation to the incorporation of informal participatory avenues and local cultural norms within broader DDR processes.

5. To unpack the broader impact of the findings on the long-term sustainability of approaches to reintegration at a societal, regional, continental and international level.
South Africa 2023-12-22 22:55:43 2026-12-22 Social Science and Humanities Non-Clinical Trial Degree Award
Sydney Gourlay
ID:
Advancing methods for measuring agricultural productivity in household surveys
REFNo: SS2185ES

In a world with increasing climate change and intensifying food insecurity, agricultural productivity is central to development. Increasing agricultural productivity requires a detailed understanding of cultivated land and its limitations, and how these shortcomings can be addressed. Towards this end, getting more reliable data on land quality and quantity, two critical elements in agricultural production, is essential for accurately estimating agricultural productivity indicators like crop yield as well as for correctly identifying key agricultural relationships, such as the often-cited inverse land size-productivity relationship. Recent technological advancements both in the areas of in field soil measurement as well as GPS-based area measurement offer promises to this respect. However, there is a need to test and validate some of the most promising methods to assess their cost-effectiveness and potential for scalability in the context of large-scale surveys and vis-à-vis more traditional improved approaches such as the elicitation of subjective and observational information in household level questionnaires.

The primary objectives of this study are:
1. Improve the measurement of agricultural productivity in household surveys
2. Test and validate innovative methods for soil health and land area measurement in the context of household surveys
3. Assess cost-effectiveness of the different methods for scaling up in national surveys

The objectives, methods and relevant literature are presented in the proposal (attached), by domain of research: soil health, land area measurement, and agricultural production measurement.

USA 2023-12-22 22:53:15 2026-12-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
WILLY RUKUNDO
ID:
Glycemic control and its contributing factors among diabetic patients attending outpatient clinic at Bugangari HC IV Rukungiri district Southwestern Uganda
REFNo: HS3357ES

To assess behavioural factors contributing to glycemic control among diabetic patients attending outpatient clinic at Bugangari HC IV in Rukungiri district.,To assess clinical factors contributing to poor glycemic control among diabetic patients attending outpatient clinic at Bugangari HC IV in Rukungiri district.,To assess socio-demographic factors contributing to poor glycemic control among diabetic patients attending outpatient clinic at Bugangari HC IV in Rukungiri district South Western Uganda,To assess poor glycemic control and its contributing factors among diabetic patients attending outpatient clinic at Bugangari HC IV in Rukungiri district South Western Uganda.,
Uganda 2023-12-22 22:52:09 2026-12-22 Medical and Health Sciences Non-Clinical Trial Degree Award
JULIET NAKABUYE MUSOKE
ID: UNCST-2022-R009890
The Politicization of COVID-19 in Uganda: A Critical Reflection on Government Interventions, Associated Risks, and Resilience Levels.
REFNo: SS1999ES

It also aims to measure the resilience levels of the masses in the face of these interventions. Government interventions against COVID-19 included closure of schools, markets, public and private transport among others. ,This study aims to critically analyze the risks emanating from government interventionand measures against the pandemic. It also aims to measure the resilience levels of the masses in the face of these interventions.,
Uganda 2023-12-21 21:42:39 2026-12-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
CHRONIC RESPIRATORY DISEASE OBSERVATORY FOR AFRICA (CHEST-AFRICA) UGANDA SITE SPECIFIC PROTOCOL
REFNo: HS3371ES

4. To assess the cost of care for asthma and COPD in Uganda,3. To assess the availability and affordability of diagnostic facilities and medicines for the management of asthma and COPD.,2. To describe the burden of symptoms, frequency and severity of exacerbations, emergency visits, and hospitalization for asthma in children aged 6-7 years in Uganda.,1. To determine the prevalence of asthma among children aged 6-7 years in Uganda.,
Uganda 2023-12-21 21:41:47 2026-12-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Mulindwa
ID:
Understanding cell-to-cell heterogeneity in Animal Trypanosome field isolates
REFNo: NS671ES

i. To develop a protocol for isolation of single trypanosomes from infected animals and adaptation of clonal micro-populations to cell culture medium.

ii. To compare the transcriptome profiles and VSG switching dynamics of micro-populations grown from field isolates.

iii. To determine the expression quantitative trait loci associated with cell-to-cell heterogeneity in trypanosome field isolates.

iv. To phenotype virulence and differentiation profiles of the diverse trypanosome isolate micro-populations.

Uganda 2023-12-21 21:39:30 2026-12-21 Natural Sciences Non-Clinical Trial Degree Award
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