Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jane Nabwowe -
ID:
ALLELE FREQUENCY DATABASE FOR 21 SHORT TANDEM REPEATS IN THE UGANDAN POPULATION
REFNo: NS716ES

To establish the Ugandan population Y-Chromosome haplotype frequency database,To develop Ugandan population specific 21 autosomal STR markers and Y- chromosome haplotype markers allele frequency data ,To determine population genetic homogeneity among the selected tribes in Uganda ,To determine the genetic diversity of the 21 STRs in a Ugandan population by calculating the forensic and paternity efficiency parameters ,
 Uganda 2024-01-23 18:56:08 2027-01-23 Natural Sciences Non-Clinical Trial Non-degree Award
MARY AJIKO MARGARET
ID:
Prevalence of Paediatric burn injuries Admitted to a hospital in Teso sub-region Eastern Uganda: lessons for prevention
REFNo: HS3484ES

The main objective of this study is to investigate the causes, characteristics, patterns, geographic determinants of paediatric burns and identifying the barriers and enablers to their prevention in a home. Specific Objective of the Study 1. To examine the typical patterns and causes of paediatric burn injuries leading to hospitalization. 2. To establish care givers’ understandings of the injury to their children, considering both injury determinants and preventive means. 3. To assess the effects of various characteristics of the living area on paediatric burn injuries. 4. To determine the enablers and barriers to the creation of safe environment, the implementation of safe practices and the use of products that control or prevent childhood burn injuries in the home.
Uganda 2024-01-23 16:58:07 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Mangheni Najjingo
ID:
Women empowerment, normative influence and project outcomes in Central Uganda
REFNo: SS1942ES

To identify factors that influence women’s economic empowerment within farming communities.

To explore the community construction of femininities and how it influences women’s economic empowerment within agricultural project intervention areas.

To explore the community construction of masculinities and how it influence women’s economic empowerment within agricultural project intervention areas

To find out the factors that influence women’s economic empowerment and household food security within agricultural project intervention areas

 Uganda 2024-01-22 11:38:01 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 EFFECTIVENESS OF THE PARTNER-LED IMPLEMENTATION IN IMPROVING DIGITAL PAYMENT AND CAMPAIGN QUALITY DURING THE YELLOW FEVER CAMPAIGN IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS2221ES

To determine gender norms and relations and their influence on health workers’ response to payment systems (cash vs mobile money) and how these affect the health workers’ performance and motivation in yellow fever vaccination campaigns,To explore the effect of implementing a partner-led digital payment system on the Motivation, Satisfaction, and performance of vaccination campaign health workers,To establish the vaccination coverage of yellow fever in different geographies (equity),To document partner-led implementation process of the Yellow Fever Mass Vaccination campaign,To assess the effectiveness of partner-led Yellow Fever campaign and its effect on digital health worker payments and campaign coverage in Uganda.,
 Uganda 2024-01-22 11:26:43 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 OUTCOMES OF PEDIATRIC PATIENTS DIAGNOSED BY MORPHOLOGY ALONE VERSUS FLOW CYTOMETRY PLUS MORPHOLOGY: A RETROSPECTIVE STUDY
REFNo: HS3352ES

To compare the treatment outcomes between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To determine the accuracy of diagnosis of acute leukemia between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To assess the time to treatment initiation among patients diagnosed with the help of flow cytometry and those diagnosed without the help of flow cytometry,
 Uganda 2024-01-22 11:25:41 2027-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Using Video-Enhanced Teaching to Increase Maternal Participation in Neonatal Hospital Care
REFNo: SS2030ES

3. To evaluate by survey the perspectives of healthcare workers on their availability to devote to video-assisted maternal education in a neonatal hospital unit in Uganda.,2. To identify maternal and/or neonatal factors that impact the amount of time needed to train mothers to weigh their baby, assess for danger signs, and track feeds using video-assisted teaching.,1. To determine the mean nursing time required to train mothers to perform three specific tasks: (1) weigh their baby, (2) assess for danger signs, and (3) track feeds when facilitated by video-assisted teaching.,The purpose of this study is to evaluate a video that teaches mothers how to monitor their baby in a neonatal hospital unit in Uganda. This is with the goal of reducing the amount of time healthcare workers need to spend teaching mothers and ultimately improving the quality of care that sick and small newborns receive in the hospital. ,
 Uganda 2024-01-22 10:45:51 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kebirungi
ID:
A QUALITATIVE STUDY ON THE CAUSES OF SLOW ADOPTION OF VIRTUAL REALITY IN MEDICAL EDUCATION IN KAMPALA, UGANDA
REFNo: SIR261ES

Primary objective: To assess the causes of slow adoption of VR in medical education in Kampala ,Uganda Secondary objectives: 1. To identify perceptions of medical students, interns, lecturers at Makerere School of Medicine, doctors and medical association leads in Kampala towards use of VR in medical education. 2.To assess the VR programming capacity in Kampala, Uganda 3 To identify key policy guidelines that would empower VR in Uganda.
Uganda 2024-01-11 13:14:59 2027-01-11 Engineering and Technology Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Regulating alcohol packaging and supply to protect health in Sub-Saharan Africa: evidence from policy systems in Malawi and Uganda (RAPSSA study)
REFNo: HS3130ES

General objective
1. To identify how regulatory controls on alcohol production and distribution can be improved and effectively implemented in Sub-Saharan Africa to reduce the availability of cheap, single-use products and related harms
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.


Specific objectives

1. To identify the adoption and formulation of the bans, what mechanisms for implementation were proposed and put in place, how the bans were enforced in practice, as well as stakeholder and public perceptions of, and explanations for, intended and unintended consequences of the bans.
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.

 Uganda 2024-01-11 12:40:52 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
 Evaluation of the impact of the Public Justice System strengthening program on violence against women and children in Uganda
REFNo: SS1980ES

d) To measure change in the status of empowerment and protection of women and children against sexual and intimate partner violence including establishing the prevalence of violence against women and children. ,c) To assess change in the performance of the justice system in prevention and response to violence against women and children in Uganda, with a focus on the ability of the criminal justice processes to secure justice for victims of intimate partner violence and sexual violence against children, b) To explore changes in stakeholder confidence in the criminal justice system and the reliance of victims / survivors of intimate partner violence and child sexual violence on the criminal justice system for redress. ,a) To assess the coherence and relevance of IJM’s VAWC program including profiling changes in the legal landscape, framework and processes for handling cases of violence against women and children in Uganda,The general aim of the study is to evaluate how strengthening the public justice system to enforce law (supply side) and empowerment of sexual and intimate partner violence survivors to undertake justice (demand side) contribute towards the protection of children and women from sexual and intimate partner violence. The evaluation will be guided by the Organization for Economic Co-operation and Development (OECD) Development Assistance Committee (DAC) evaluation criteria of Relevance, Coherence, Effectiveness, Efficiency, Impact, and Sustainability to measure impact,
 Uganda 2024-01-11 12:39:14 2027-01-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
DENIS OKELLO
ID:
Profiling Medicinal Plants and the Corresponding Community Conservation Practices within Kigezi Region
REFNo: NS667ES

Assess the community conservation strategies for priority medicinal plants in Kanungu, Kisoro and Rubanda districts.,To assess the cultural practices in Kanungu, Kisoro and Rubanda districts to ensure sustainable utilization and knowledge transfer of the medicinal values of these plants.,To assess traditional knowledge practices regarding medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To identify and document medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To profile medicinal plants in Kanungu, Kisoro and Rubanda districts in Kigezi region and assess local community conservation practices,
 Uganda 2024-01-11 12:35:14 2027-01-11 Natural Sciences Non-Clinical Trial Non-degree Award
Richard Mayanja
ID:
Genetic Determinants of Kidney Function in Sub-Saharan Africa
REFNo: HS3372ES

The overall aim of this project is to identify the genetic determinants of chronic kidney disease in sub-Saharan Africa
 Uganda 2024-01-11 12:32:07 2027-01-11 Medical and Health Sciences Non-Clinical Trial Degree Award
John Mark Bwanika
ID:
BUILDING MACHINE LEARNING ALGORITHMS FOR PREDICTIVE MODELLING OF THE ABILITY TO PAY FOR PRE-EXPOSURE (PREP) SERVICES, A PILOT STUDY IN KAMPALA, UGANDA.
REFNo: HS3474ES

Primary objective:
To develop and deploy an artificial intelligence (AI) modelling technique for PrEP services market segmentation.
Secondary objectives:
(i) To use machine learning and artificial intelligence modelling to analyze, and profile sub-populations that are able to pay for PrEP in Kampala.
(ii) To identify the most likely favorable pricing for PrEP
(iii) To validate the variables identified as predictors for PrEP payment from dataset analyses through focus group discussions.
(iv) To test the validity and reciprocity of the developed AI model with similar datasets from other settings.

 Uganda 2024-01-11 12:31:29 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of Clinical Performance and Usability of the KHB HIV I/II Ab Rapid Test (Self-Test) in the hands of untrained users. "Clinical Performance Study Plan - CPSP nr. KHB-CPH 23-039"
REFNo: HS3531ES

The objective of this laymen study is to establish and to qualify the usability of the KHB HIV Self-Test for self-testing in a low and a high prevalence HIV setting in Uganda as described in TSS-1 part 3. In addition, the layperson’s interaction with the device in terms of effectiveness and efficiency, i.e. successful/unsuccessful completion and difficulty of the critical steps as per Instructions for Use will be assessed. ,
 Uganda 2024-01-11 12:30:09 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zubair Lukyamuzi
ID: UNCST-2021-R013107
 Feasibility and Acceptability of a Barbershop Based HIV Prevention Initiative Among Heterosexual Men in Kalangala Islands, Uganda: A Cluster Randomized Trial
REFNo: HS3430ES

1. To compare completion of self-initiated HIV testing between intervention and control groups
2. To evaluate the preliminary effectiveness of the intervention on change in behaviors associated with HIV acquisition
3. To compare interest in or use of HIV prevention services between intervention and control groups
4. To evaluate the preliminary effectiveness of the intervention on incident STIs
Uganda 2024-01-08 13:20:21 2027-01-08 Medical and Health Sciences Clinical Trial Non-degree Award
Tumuhimbise Jasper Mpiriirwe
ID:
HEAD TEACHERS’ LEADERSHIP PRACTICES AND FINANCIAL PERFORMANCE IN CHURCH OF UGANDA FOUNDED SECONDARY SCHOOLS IN NAMIREMBE DIOCESE
REFNo: SS2126ES

4. To explore the influence of head teachers’ stakeholder collaboration on financial performance in the Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,3. To analyze the influence head teacher’s team leadership practices on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese in Namirembe Diocese.,2. To assess the influence of head teachers’ values on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,1. To examine the influence of head teachers’ vision on financial performance of Church of Uganda Founded Secondary Schools in Namirembe Diocese.,The general objective of the study is to examine the influence of head teachers’ leadership practices on financial performance of Church of Uganda Founded Secondary Schools (CFSs) in Namirembe Diocese. ,
 Uganda 2024-01-08 13:18:02 2027-01-08 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Feasibility of Nanopore Sequencing for Classification of Pediatric Malignancies in Low Resource Settings
REFNo: HS3397ES

Expand upon our adapted unbiased Nanopore sequencing classification platform while verifying the feasibility of classification of pediatric solid tumors using GEP. Hypothesis: Unbiased Nanopore sequencing can be implemented and can accurately classify pediatric cancer in low and middle income countries,Establish technical and human resources needed to carry out local, real-time sequencing on Nanopore platforms through optimizing existing supply chains in collaboration with Nanopore and establishing standardized virtual and in-person training of local research, laboratory, and information technology support.,Optimize and validate, within the context of use in low and middle income countries, the efficacy unbiased Nanopore sequencing platform for pediatric cancer classification after integrating a Cloud-based computational analysis pipeline. Hypothesis: Using a Cloud-based unbiased Nanopore sequencing approach, clinical laboratories in LMIC can perform sequencing with Cloud based analytical support, accurately classify pediatric cancer diagnosis and genomic subtypes.,To determine the feasibility of implementing and utilizing Nanopore sequencing for classification of pediatric malignancies, as determined by technical quality, data management, and classification accuracy.,
 Uganda 2024-01-08 13:16:49 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Ssekamatte
ID: UNCST-2022-R010961
 Climate change health vulnerability and adaptation assessment (VAA) for sound management of climate change-related health risks in Uganda
REFNo: HS3168ES

6. To use evidence from objectives 1-5 to inform the development of a National Health Adaptation Plan (H-NAP) for effective mitigation, adaptation and response to climate change in the health sector.,5. To understand how monitoring and evaluation of mitigation, adaptation and response measures to climate-change related risks and impacts on the health sector in Uganda should be done,4. To explore what should be done to effectively mitigate, adapt and respond to climate change-related risks and impacts in the health sector in Uganda,3. To identify policies, programmes and adaptation mechanisms that should be prioritized to address current and projected health risks in the health sector in Uganda,2. To describe and quantify the potential impacts (present and future) of climate change on the health sector in Uganda,1. To describe and quantify climate-change related risks (present and future risks) on the health sector in Uganda,To conduct a national health climate change vulnerability and adaptation assessment to identify health risk factors and gaps for sound management of climate change-related health risks in Uganda,
 Uganda 2024-01-08 13:15:39 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Sanya Edwin
ID: UNCST-2023-R006836
 The Next Generation Vaccine Card: Innovative Technology to Improve Vaccine Equity in Kagando, a Rural Setting in Uganda
REFNo: HS3515ES

To implement and evaluate using cluster-randomised and pre/post intervention approaches, the ‘next generation digital vaccine card’ in Kagando Uganda I. Implement the digital vaccine card intervention in rural Uganda II. Evaluate the implementation process and effectiveness of the intervention III. Evaluate the impact of the intervention on equity at the individual and village levels. IV. Conduct an economic evaluation of the intervention.,To co-design and develop a ‘next generation digital vaccine card’ for childhood vaccinations I. Design and build a prototype digital vaccine card and registry II. Use iterative feedback to refine the digital vaccine card and registry III. Develop a Minimum Viable Product (MVP) that meets the desired stakeholder specifications,To evaluate the current routine childhood vaccination landscape in Kagando Uganda I. Assess baseline routine childhood immunisation data quality at the facility level using WHO standard indicators II. Assess equity in routine childhood immunisation coverage and timeliness using household survey data III. Collect and analyse qualitative data to understand current knowledge, attitudes, and practices of vulnerable populations from patient and provider perspectives.,To develop and evaluate a ‘digital vaccine card’ and registry that will facilitate the electronic collection of individual data at health facilities to allow improved monitoring of vaccine coverage and timeliness by both healthcare providers and parents/caregivers, in turn improving vaccine equity in rural Uganda. ,
 Uganda 2024-01-08 13:14:20 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hakim Sendagire
ID:
Clinical, Hematological and Biochemical predictors of outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study)
REFNo: HS2961ES

General Objective
To evaluate the clinical presentation, treatment, clinical chemistry, immune chemistry, hematology and other laboratory predictors of clinical outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak
Specific Objectives
1. To evaluate the clinical presentation of patients at the time of admission in the ETU and treatment offered during admission as predictors of outcome among Sudan EVD patients admitted in hospital during the 2022 Ugandan Ebola Outbreak (CHEBE Study).
2. To describe the clinical chemistry, immune chemistry, hematology and other laboratory predictors of outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study).
3. To determine the association between laboratory profiles, comorbidities and clinical outcomes among patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study).

 Uganda 2024-01-08 13:13:08 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa van Dongen Maria Angela
ID:
Belief-based poverty traps and the effects of material and psychological interventions: Evidence from a lab-in-the-field experiment in rural Uganda
REFNo: SS2137ES

This research aims to empirically study the effects of aid on beneficiaries' and non-beneficiaries' agency beliefs and effort decisions.
 Netherlands 2024-01-08 13:12:25 2027-01-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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