Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Stephen Sabiiti
ID:
CLINICAL AND HEMATOLOGICAL OUTCOMES OF CHILDREN WITH SICKLE CELL ANEMIA TREATED WITH LOW FIXED-DOSE HYDROXYUREA AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1314ES

1. To describe the clinical and hematological
features of children with sickle cell
anemia at initiation of low fixed-dose
hydroxyurea at MRRH.
2. To describe the changes in hematological
indices after initiation of low fixed dose
hydroxyurea among children with sickle
cell disease at MRRH.
3. To describe the incidence of sickle cell
anemia related clinical events among
children with sickle cell disease treated
with low fixed-dose hydroxyurea at MRRH.
4. To identify factors associated with the
changes in hemoglobin level among children
with sickle cell anemia treated with
low fixed-dose hydroxyurea at MRRH.
Rwanda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Kemigisha Kemigisha
ID:
Adolescents’ Perspectives of sexual wellbeing and consent MUST-2021-37
REFNo: HS1438ES

1) To contribute to the understanding about how local and contextual factors such as predominant religion, socially acceptable norms, cultural practices and political sentiment can influence sexual wellbeing of adolescents (10 to 24 year olds) in LMIC’s, 2) To explore adolescents’ understanding of, and perspectives on, sexual wellbeing, capturing different aspects of sexuality development during adolescence, including the evolving capacity to sexual consent,
Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ADOA DENNIS
ID:
Development and Evaluation of a Psychosocial Risk Assessment Tool for Predicting Attrition From HIV Care And Treatment Amongst Adolescents Aged 15-19 Years in Uganda
REFNo: HS1501ES

To assess the feasibility of HCWs administering the psychosocial risk assessment tool to ALHIV aged 15-19 years during routine ART visits to determine risk for attrition ,To evaluate the ability of the tool to predict risk of attrition of ALHIV aged 15-19 years at 3-months, following their enrollment date,Assessment and validation of the risk assessment tool, To develop a psychosocial risk assessment tool,To develop a psychosocial assessment tool for predicting attrition of adolescents aged 15-19 years from HIV care. ,
Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
EVALUATION OF TRUENAT MTB-RIF DX AND TRUENAT MTB ASSAYS IN COMPARISON TO GENEXPERT MTB/RIF ULTRA FOR THE DIAGNOSIS OF PULMONARY TUBERCULOSIS
REFNo: HS1526ES

Primary:
• Assess sensitivity and specificity of Truenat™ MTB-RIF Dx and Truenat™ MTB assays in raw sputum compared to the WHO-endorsed GeneXpert® MTB/RIF Ultra using culture as the gold standard

Secondary:
• Assess the operational feasibility of Truenat™ MTB-RIF Dx and Truenat™ MTB assays
• Determine and compare costs between the Truenat™ MTB-RIF Dx and Truenat™ MTB assays, and Xpert MTB/RIF Ultra
Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Lugaajju
ID:
Community-Based Cardiovascular Disease risk factors assessment in Wakiso and Mpigi districts
REFNo: HS1556ES

1. To determine the prevalence of cardiovascular disease risk factors (hypertension, dyslipidemia, obesity, diabetes, physical inactivity, diet, and age) in Wakiso and Mpigi districts
2. To determine the status of cardiac function of the study participants in Wakiso and Mpigi districts.
3. To explore determinants of life-style factors (physical activity, tobacco and alcohol use) through interviews and focus group discussions
Uganda 2021-08-06 2024-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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