Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Soofia Mahmood
ID: UNCST-2025-R022700
DATA-DRIVEN TARGETING AND ADAPTATIONS FOR SCALING ULTRA POVERTY GRADUATION (UPG) IN MID WEST AND SOUTH WESTERN UGANDA
REFNo: SS5421ES

1. To assess whether data-informed prioritization of vulnerable households for individual coaching check-ins improves practice adoption and household economic outcomes. 2. To compare group enterprise investment and individual lending models in building sustainable for women-led Village Savings and Loan Associations (VSLAs) and improving economic outcomes for members. 3. To evaluate whether government staff can deliver household coaching with effectiveness compared to RTV staff when using the same tools and implementation approach.
Canada 2026-06-12 3:42:23 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elisabeth Gerwing-Adima
ID: UNCST-2026-R025356
Determining the Burden and Drivers of Stigma and Mental Health Among Individuals with Lived Experience of Leprosy in Uganda.
REFNo: HS7717ES

General objective
The general objective of this study is to determine the burden and the drivers of mental health burden and stigmatization of those affected by leprosy in Uganda, to inform policy makers and enable effective intervention development. Specific objectives:1. To assess the mental health burden among people affected by leprosy in Uganda, by investigating both the burden of the mental distress (quantitative) and the lived experiences of patients (qualitative).
2. To determine the burden of leprosy-related stigmatization in the Mayuge district, Uganda (quantitative), and explore in-depth how leprosy stigmatization is experienced (qualitative).


Germany 2026-06-12 3:40:43 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Nabayinda
ID: UNCST-2026-R023998
Examining the intersection of climate change and Intimate partner violence among young women living with HIV
REFNo: SS5395ES

General Objective: The overall objective of the study is to examine how climate-induced disasters interact with IPV, poverty and mental health to influence ART adherence among YWLHIV in Eastern Uganda. Specific Objectives: 1) To Quantitatively assess the extent to which poverty and mental health mediate the relationship between climate-induced disasters and IPV among YWLHIV in Eastern Uganda; 2) Qualitatively explore young women’s lived experiences and stake holders perspectives of how climate-induced disruptions (e.g., disasters, resource scarcity) affect access to HIV treatment and adherence.
Uganda 2026-06-12 17:17:32 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sheila Bamweyana
ID: UNCST-2026-R024037
HPTN 104: A multisite, open-label, randomized crossover study comparing adherence to a single daily dual prevention pill (DPP) versus FTC/TDF and Combined Oral Contraception separate pill dosing (2PR), given for pre-exposure prophylaxis and pregnancy prevention in women.
REFNo: HS7679ES

Primary Objective(s):
-Compare PrEP adherence to the DPP versus 2PR during a randomized crossover period.


Secondary Objectives:
-Compare PrEP adherence to the DPP versus 2PR during a Choice period.

-Evaluate acceptability of DPP versus 2PR during crossover and Choice periods.

-Evaluate preferences for the DPP versus 2PR.

-Compare PrEP persistence on the DPP versus 2PR during the Choice period.

-Compare the tolerability, side effects and unintended consequences (e.g., Intimate Partner Violence [IPV], pregnancy, HIV) of DPP versus 2PR: overall, during crossover and Choice periods.


Exploratory Objective:
-Examine facilitators and barriers of DPP adherence, acceptability, and persistence, during the crossover period and during Choice periods.

-Use mathematical modeling to estimate the effectiveness of the DPP and 2PR in reducing HIV incidence within the study cohort during the crossover and Choice periods.


Uganda 2026-06-12 17:15:26 2029-06-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Musiime -
ID: UNCST-2021-R013794
The AWARE-Kampala Study (Air Pollution and Well-Being: Assessing Risks and Enhancing Education among adolescents in Kampala)
REFNo: SS5260ES

The overarching objective is to understand knowledge, attitudes, and perceptions of air pollution and health among adolescents in Kampala using focus group discussions grounded in the Health Belief Model.
Uganda 2026-06-12 17:08:59 2029-06-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
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