Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jonathan Presley
ID:
RIGHTS. The bargaining power of sending countries in influencing the rights of their low skilled migrant workers
REFNo: SS3001ES

1)To determine what actions Uganda take to support access to (human and labor) rights of their low-skilled migrant workers in high-income countries.
2)To explore the motivations of origin countries to take – or not take – specific actions.
3)To explore how the (inter)actions of origin and destination countries, interstate dialogues, the involvement of civil society actors in origin and destination countries, and international organizations shape the rights of low skilled migrant workers in high income countries.
 USA 2024-08-29 18:25:40 2027-08-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Michael  Brown Obeng
ID:
Social Innovation and Health Technologies for Community Health Workers: An Afro-centric Perspective
REFNo: SS3003ES

To develop an alternative theoretical model to account for Afro-centric perspectives when deploying of socially innovative health technologies for CHWs in Uganda that contributes to the advancement of the field of social innovation theory,To co-design strategies that incorporate Afro-centric views, including cultural and social context, when deploying socially innovative health technologies for CHWs in rural Uganda ,To explore factors that promote community engagement in order to understand how the Afro-centric perspectives can be leveraged when deploying of socially innovative health technologies for CHWs in rural Uganda,To compare existing health technologies with the conventional paper- based systems utilised by community health workers (CHWs) in the context of rural Uganda.,
 Ghana 2024-08-29 18:16:46 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Kirumira
ID: UNCST-2022-R009435
 CONTEXTUAL FACTORS AND OPERATIONAL PERFORMANCE OF MEDICAL IMAGING SERVICES IN CHRISTIAN FAITH BASED HOSPITALS IN UGANDA: A CASE STUDY OF MENGO HOSPITAL AND UGANDA MARTYRS’ HOSPITAL LUBAGA
REFNo: HS4710ES

1. To examine how the Managerial environment ensures equipment utilisation and maintenance in Medical Imaging Services of Mengo Hospital and Uganda Martyrs' Hospital Lubaga
2. To examine the effect of the regulatory environment on staff productivity in the Medical Imaging Services of Mengo Hospital and Uganda Martyrs' Hospital Lubaga
3. To evaluate the contribution of the competition environment to patient satisfaction with Medical Imaging Services of Mengo Hospital and Uganda Martyrs' Hospital Lubaga
4. To analyse the relationship between contextual factors and operational performance of Medical Imaging Services in Mengo Hospital and Uganda Martyrs' Hospital Lubaga

 Uganda 2024-08-29 13:37:05 2027-08-29 Medical and Health Sciences Non-Clinical Trial Degree Award
William Buwembo
ID: UNCST-2022-R009661
 Strengthening HIV Oral Health Human Resource for Research Capacity in Uganda.
REFNo: HS4603ES

To mobilize research training resources and partnerships for HIV related oral health research.,To determine the current research training needs for oral health in HIV among health care providers in Uganda.,The goal of this planning proposal is to identify training needs that will facilitate the development of a robust stake-holder informed training program (D43 application) to strengthen HIV oral health research in Uganda.,
 Uganda 2024-08-29 13:32:07 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ephrance  Namugenyi Eunice
ID:
Adaptive Network Communications Architecture for Transmission of Sensor Data in the Framework of Beehive Management.
REFNo: SIR382ES

Objective 1: Conduct Requirements Analysis and Design: Identify and analyze the requirements for an adaptive network communications architecture tailored for beehive monitoring units, focusing on the transmission of sensor data with specified communication modules (LoRa, Wi-Fi, and GSM) for various environmental test case scenarios. Document the requirements and design specifications within the first year, ensuring the design addresses the unique challenges of remote beekeeping environments and utilizing existing knowledge and technology to outline feasible network requirements and designs.,To design, develop, and evaluate a reliable adaptive network communications architecture that optimizes the transmission of sensor data for efficient and intelligent monitoring of beehive management, based on real-time environmental conditions, resource availability, and application-specific requirements over a three-year period., Objective 2: Develop and Integrate Machine Learning Optimization Algorithms: Develop and integrate machine learning algorithms that optimize the network\'s operation modes and data transmission prioritization based on real-time environmental conditions and network resource availability. Implement and test these algorithms in a controlled setting, leveraging existing machine learning frameworks and expertise. Enhance the adaptability and efficiency of the network to ensure it is suitable for energy-constrained and variable environments. Finalize the development and initial testing by the end of the second year., Objective 3: Evaluate Network Performance and Effectiveness: Conduct simulations, experimental analyses, and field demonstrations to evaluate the performance and effectiveness of the developed adaptive hybrid backhaul network (LoRa, Wi-Fi, and GSM) for different deployment scenarios in beehive management. Measure key performance indicators such as data throughput, latency, power consumption, and reliability across various scenarios. Use simulation tools and real-world testing environments to gather relevant data. Validate the network\'s performance to ensure it meets the requirements for efficient sensor data transmission in beehive monitoring. Complete all evaluations, analyses, and demonstrations by the end of the third year.,
 Uganda 2024-08-29 13:29:16 2027-08-29 Engineering and Technology Non-Clinical Trial Degree Award
Paul Lutaakome
ID:
DIETARY QUALITY AND ITS CORRELATES AMONG PATIENTS DIAGNOSED WITH CARDIOVASCULAR DISEASES AT THE UGANDA HEART INSTITUTE – KAMPALA UGANDA
REFNo: HS3899ES

4. To establish the institutional correlates of dietary quality among patients diagnosed with cardiovascular diseases at the Uganda heart institute – Kampala Uganda,3. To determine the intra-household correlates of dietary quality among patients diagnosed with cardiovascular diseases at the Uganda heart institute – Kampala Uganda,2. To identify intrapersonal correlates of dietary quality among patients diagnosed with cardiovascular diseases at the Uganda heart institute – Kampala Uganda,1. To determine the proportion of patients diagnosed with cardiovascular diseases at the Uganda heart institute, who have satisfactory dietary quality,To assess dietary quality and its correlates among patients diagnosed with cardiovascular diseases at the Uganda heart institute – Kampala Uganda.,
 Uganda 2024-08-29 11:01:41 2027-08-29 Medical and Health Sciences Non-Clinical Trial Degree Award
GUMA  ASHIRAF
ID:
PREVALENCE, PATTERNS AND CORRELATES OF GENERAL JOINT PAIN AMONG PATIENTS WITH DIABETES MELLITUS ATTENDING DIABETIC CLINIC AT MBARARA REGIONAL REFFERRAL HOSPITAL
REFNo: HS3963ES

To determine the prevalence of general joint pain among patients with DM attending diabetes clinic at MRRH.To determine the patterns of joint pain among patients with DM attending diabetes clinic at MRRH.To determine the associated factors to general joint pain among patients with DM attending diabetes clinic at MRRH.
 Uganda 2024-08-29 10:59:36 2027-08-29 Medical and Health Sciences Clinical Trial Degree Award
Esther Bibangambah Mulungi Nabatanzi
ID: UNCST-2024-R004669
 Health Related Quality of Life of children with Cerebral Palsy in Wakiso District: An Explorative interventional study
REFNo: HS4516ES

4. Evaluate the impact of both hospital-based and community-based early intervention program on Health-Related Quality of Life of children with Cerebral Palsy and the depression anxiety and stress level of their primary caregivers. ,3. Define the depression, anxiety and stress of primary caregivers of children with Cerebral Palsy in Wakiso, Uganda,2. Define the Health-Related Quality of Life of children with CP in Wakiso, Uganda,1. Define the epidemiology of Cerebral Palsy in Wakiso, Uganda,We aim to establish a cohort of children with CP in the Wakiso district of Uganda to define the epidemiology of CP, describe the HRQoL of the children with CP and depression, anxiety and stress level their primary caregivers to evaluate the impact of any community-based early intervention. ,
 Uganda 2024-08-28 18:51:55 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ACEN CATHERINE BOKELLO
ID: UNCST-2024-R004924
 Internal Control Systems and Public Financial Management in Selected Local Governments in Uganda
REFNo: SS2809ES

To determine the significant relationship between monitoring and public financial management in selected local governments in Uganda.,To establish the influence of communication on public financial management in selected local governments in Uganda,To establish the effect of control activities on public financial management in selected local governments in Uganda,To establish the influence of risk assessment on public financial management in selected local governments in Uganda.,To determine the effects of control environment on public financial management in selected local governments in Uganda,To assess the effects of internal control systems on public financial management in selected Local Governments, in Uganda.,
 Uganda 2024-08-28 18:49:02 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Beatrice Kyasiimire
ID:
Living near Uganda’s Queen Elizabeth National Park; evaluating alternative livelihood initiatives
REFNo: NS830ES

Assess communities\' governance structures and systems\' impacts on alternative livelihoods around the park.,Assess community and external actors\' perceptions of the enabling conditions for alternative livelihood projects around the park.,Evaluate the enabling conditions for alternative livelihood projects in communities around Queen Elizabeth National Park.,The overall aim of this study is to understand the enabling conditions influencing the implementation and effectiveness of alternative livelihoods around Queen Elizabeth National Park. ,
 Uganda 2024-08-28 18:46:54 2027-08-28 Natural Sciences Non-Clinical Trial Degree Award
SHAFIGA BABIRYE
ID: UNCST-2024-R004302
 LEVEL AND PREDICTORS OF CATASTROPHIC HEALTH EXPENDITURE AMONG RECIPIENTS OF AMBULATORY SURGICAL SERVICES AT KYABIRWA SURGICAL CENTER
REFNo: SS2900ES

To establish the intra-household predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To analyze the clinical predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the intrapersonal predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To determine the prevalence of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the level and predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,
 Uganda 2024-08-28 18:41:10 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 Exploring the Nexus of Clean Water Access and Sexual Reproductive Health among Women and Girls in Rural Uganda
REFNo: SS2829ES

1. How do socio-cultural contexts, such as traditional gender roles and community expectations, shape the challenges women and girls face when accessing clean water?
2. How do power dynamics influence the management, utilization, and involvement of women in activities related to water access?
3. What role does education play on the awareness and implementation of Sexual Reproductive Health practices among women and girls?

Uganda 2024-08-28 18:39:31 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hadijah Yahyah
ID:
Assessing the Environmental Sustainability Implications of Farm-Level Persistent Organic Pollutant Pesticide Use in Uganda
REFNo: SS2683ES

1. To examine the pathways for the transmission of POPs pesticides into Mukono District;
2. To evaluate the trends and characteristics of farm level use of POP pesticides into Mukono District;
3. To assess the role and level of knowledge, attitudes and practices of farmers in decision making for POPs pesticide use in Mukono District;
4. To assess the adequacy of the existing structures , tools, and approaches for the regulation of importation and farm-level use of POP pesticides in Uganda;

 Uganda 2024-08-28 18:31:37 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Nakaye
ID: UNCST-2021-R013222
 FEASIBILITY, ACCEPTABILITY, AND PERSISTENCE OF COMMUNITY DRUG SHOP-BASED HIV SELF-TESTING AND ORAL PREP DELIVERY AMONG FEMALE SEX WORKERS IN KITEBI, KAMPALA CAPITAL CITY, CENTRAL UGANDA (DROP-D).
REFNo: HS4556ES

Examine FSW and community drug shop PrEP providers’ experiences, preferences, barriers, and facilitators related to the community drug shop based HIVST and oral PrEP delivery model,Assess persistence of community drug shop-based HIVST and oral PrEP delivery among FSW in Kampala,Assess the feasibility and acceptability of utilising community drug shops to offer HIVST and oral PrEP delivery among FSW in Kampala,
 Uganda 2024-08-28 18:28:21 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Semyalo Paul Ddumba
ID: UNCST-2021-R012585
 RISING INEQUALITIES OCCASIONED BY COVID-19 IMPACTS IN URBAN INFORMAL SETTLEMENT IN UGANDA (CASE STUDY OF ACCESS AND USE OF SAFE WATER IN KAMPALA SLUM AREAS)
REFNo: NS746ES

To assess microbiological and physicochemical water quality both at the source and household reserves, as well as carryout sanitation risk assessment of the different water sources in Kisenyi.,To assess the patterns of access to and utilization of safe water among households in Kisenyi, Central Division, examining the changes that occurred before, during, and after the COVID-19 pandemic.,To investigate the diverse socio-economic determinants of households in Kisenyi which influences their choice of water source and how this was impacted by COVID-19.,Examine the multifaceted impact of the COVID-19 pandemic on the exacerbation of social and economic inequalities among the urban poor, with a specific focus on access to Water, Sanitation, and Hygiene (WASH) services, as a means to gain insights and inform strategies for addressing these disparities.,
 Uganda 2024-08-28 18:19:09 2027-08-28 Natural Sciences Non-Clinical Trial Non-degree Award
ERINAH MUDONDO -
ID:
Liquidity management practices and Financial performance of banking institution in Kampala metropolitan - Uganda
REFNo: SS2872ES

To establish the influence of liquidity risk on the financial performance of banking institutions in Kampala Metropolitan.,To investigate the influence of liquidity management practices on financial performance of banking institutions in Kampala Metropolitan, Uganda.,
 Uganda 2024-08-28 18:17:15 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Downing George
ID: UNCST-2020-R014615
 A prospective, multi-centre study to evaluate the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test.
REFNo: HS4648ES


The primary objective of this study is:
• To determine the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test results using fingerstick capillary whole blood, venous whole blood, serum and venous plasma, when the test is performed by professional users.

The reference test will be Elecsys® Syphilis test (Roche). This test is an electrochemiluminescence immunoassay for the qualitative determination of total antibodies against Treponema pallidum. Samples with a negative Elecsys Syphilis result will be considered reference test-negative. Samples with a positive Elecsys Syphilis result will be confirmed by Treponema Pallidum Particle Agglutination (TPPA) testing. The TPPA result must be positive for the sample to be considered reference test-positive. Samples with a positive Elecsys Syphilis result but a negative or indeterminate TPPA result will be considered indeterminate and excluded from the study analyses. Potential discrepant result resolution using the Abbott Architect i1000SR Syphilis chemiluminescent microparticle immunoassay may be conducted for study reference test-positive or reference test-negative samples with discrepant investigational test results. The results from potential discrepant result resolution testing will be presented as table footnotes only. In addition to these treponemal tests, non-treponemal RPR testing will also be conducted for the reference test-positive participants, and the results may be stratified also by RPR status. All discrepant specimens shall be repeated using the same lot of RDT, and then on all available lots and any variability noted.

Another primary study objective is to compare the performance of the Determine Syphilis Advanced test with two commercially available similar tests, to meet the regulatory requirements in Japan. These two commercially available tests will be the TPPA test (SERODIA-TPPA, Fujirebio, Japan) and the Determine Syphilis TP test (Abbott). This analysis will be performed using 60 reference test-positive samples and 60 reference test-negative samples. The testing will be performed using plasma.

One study secondary objective is to evaluate the usability through completion of a user experience questionnaire (healthcare and laboratory staff).

Another study secondary objective is to determine the stability of venous whole blood, serum and plasma samples for use with Determine Syphilis Advanced, after refrigeration of the venous whole blood, serum and plasma at 2-8 degrees Celsius during 7 days before testing.

 UK 2024-08-28 17:34:38 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hillary Agaba
ID:
Understanding experiences of participating in a farmer research network from multiple perspectives in the Agroecology - Landscape project in Eastern Uganda
REFNo: SS2707ES

Provide an overview of the diversity of experiences across the Collaborative Resilient Food Systems (CRFS) countries, and different projects within countries, in ESAf. ,Gain more understanding of how FRN groups have developed and are functioning from the perspectives of those involved, ,Document the experience of participating in Farmer Research network (FRN) from multiple perspectives: farmers, researchers, NGO field staff and extension workers;,
 Uganda 2024-08-28 17:32:34 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Comparing the Diagnostic Performance of the Rapid Tick Exposure Test (RaTexT®) and Larval Packet Test [LPT] for Acaricide Resistance Management in Uganda
REFNo: NS843ES

The general objective of this study will be to determine the diagnostic performance of RaTexT® compared to larval packet technique, test a mobile application for its ability to capture acaricide resistance data generated by RaTexT® and transmit it to end users as dynamic maps of acaricide resistance as well as determine the gender roles that are likely to underpin successful RaTexT® introduction. The specific objectives of this acaricide study will be to determine:
i.Laboratory and field diagnostic performance [specificity, sensitivity, negative and positive predictive values] of RaTexT® when used to detect acaricide resistance in tick populations isolated from different agro-ecological zones of Uganda.
ii. Possibility of integrating RaTexT® -generated acaricide resistance | susceptibility data into a mobile phone app to allow end-users to create dynamic maps of acaricide resistance in different African ecologies.
iii.Gender-based drivers of successful introduction and sustainable utilisation of RaTexT®

 Uganda 2024-08-28 17:31:08 2027-08-28 Natural Sciences Non-Clinical Trial Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
 Zinc for Infection Prevention in Sickle cell anemia ZIPS-2
REFNo: HS4824ES

The primary objective of the study is to determine if zinc supplementation at 20mg daily is safe and efficacious at reducing all-cause infection in Ugandan children 1.00-4.99 years of age with SCA.Secondary objectives 1. To determine the incidence of adverse events requiring discontinuation of study drug in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 2. To determine the incidence of stroke or death in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 3. To determine the incidence of infections requiring hospitalization in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 4. To determine the incidence of vaso-occlusive crises in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 5. To determine the change in transcranial Doppler (TCD) velocity from enrollment to 6-month study endpoint in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 6. To determine change in serum zinc deficiency status from enrollment to 6-month study endpoint in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 7. To determine the incidence of serious adverse events in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 8. To determine the incidence of adverse events in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo
Uganda 2024-08-28 17:29:12 2027-08-28 Medical and Health Sciences Clinical Trial Non-degree Award
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