Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Patrick Vudriko
ID: UNCST-2025-R019645
Unravelling the ecology of ticks and tick-borne pathogens at the wildlife-livestock interface in South Western Uganda (ECOTIP Project)
REFNo: HS8771ES

1.1 General objective
We propose a study aimed at unravelling and clarifying tick ecology and the epidemiologies of
TBP infections of medical, veterinary and zoonotic importance in and around QENP.
1.2 Specific objectives
The study specifically seeks to:
1. Characterise the diversity of tick species and their density including: i) ticks that are
host-seeking (“questing”) on vegetation or, ii) ticks infesting various vertebrate wildlife,
livestock and domestic animals in and around QENP;
2. Detect and characterise the TBPs infecting: i) questing ticks and ii) ticks infesting wildlife
and domestic animals and associate TBPs with tick species;
3. Create a comprehensive database of microorganisms infecting Ugandan ticks, including
novel bacteria, parasites and viruses to enhance preparedness for emerging outbreaks
of unknown aetiology;
4. Analyse the genetic structure of ticks to support the understanding of the geographical
spread of tick populations associated with vertebrate hosts, TBPs or environmental
factors;
5. Build national capacity for research and surveillance of ticks and tick-borne diseases by
(i) equipping laboratories, and (ii) delivering bespoke training events for Ugandan
scientists;
6. Work with relevant policymakers including UWA to provide data and scientific reports to
support efforts to mitigate conflict between conservationists and pastoralists in and
around QENP.
Uganda 2026-10-14 20:24:56 2029-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Bukuluki
ID:
Girls and Vulnerable Children's Readiness to Transition from Early Learning to Primary: A Longitudinal Study in Buyende, Lyantonde and Isingiro Districts in Uganda.
REFNo: SS6207ES

1. To assess individual level factors that influence girls' and vulnerable children's readiness to transition from early learning to primary school.
2. To explore the family level barriers and enablers for girls and vulnerable groups' readiness to transition from early learning to primary education.
3. To find out the existing social/gender norms and attitudes that influence girls and vulnerable children's readiness to transition from early learning to primary school.
4. To establish institutional factors that affect girls' and vulnerable groups' readiness transition from early learning to primary.

Uganda 2026-10-14 20:23:25 2029-10-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
BANNET BIRUNGI
ID: UNCST-2026-R028165
PARADOXICAL LEADERSHIP AND TEAM COHESION OF ACADEMIC STAFF IN UGANDAN PUBLIC UNIVERSITIES: MEDIATION AND MODERATION OF COMMUNICATION AND ORGANISATIONAL CULTURE
REFNo: SS6049ES

The purpose of the proposed study is to investigate the influence of paradoxical leadership on team cohesion of academic staff moderated and mediated by organisational culture and communication in Public Universities in Uganda.
1.4 Specific Objective
i. To examine the influence of paradoxical leadership on team cohesion of academic staff in Public Universities in Uganda.
ii. To assess the influence of paradoxical leadership on organisational communication in Public Universities in Uganda.
iii. To analyse the influence of organizational communication on team cohesion of academic staff in Public Universities in Uganda
iv. To examine the influence of organizational culture on team cohesion of academic staff in Public Universities in Uganda
v. To test the mediation of organizational communication on the influence of paradoxical leadership on team cohesion of academic staff in Public Universities in Uganda.
vi. To test the moderation of organizational culture on the influence of paradoxical leadership on team cohesion of academic staff in Public Universities in Uganda

Uganda 2026-10-14 20:14:16 2029-10-14 Social Science and Humanities Degree Award
Wandera Joseph
ID: UNCST-2026-R026613
REFUGEE POLICY AND THE QUALITY OF LIFE IN THE SELECTED REFUGEE SETTLEMENTS IN UGANDA
REFNo: SS6202ES

(i) To examine the effects of legal frameworks on the quality of life in the selected refugee settlements in Uganda. (ii) To assess the effects of refugee integration policy frameworks on the quality of life in the selected settlements in Uganda. (iii) To establish the effects of refugee social support programs on the quality of life in the selected settlements in Uganda. (iv) To assess the effects of development partners in the relationship between refuge policy and quality of life in the selected refugee settlements in Uganda.
Uganda 2026-10-14 20:11:10 2029-10-14 Social Science and Humanities Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
DOCK-TB: Decentralized Onsite Cascade-impact with MiniDocK for TB
REFNo: HS8808ES

To characterize shifts in the demographic and risk profile of persons identified as presumptive TB and persons completing TB testing at intervention vs. comparison health centers, to assess whether swab-based testing expands case-finding beyond symptomatic self-presenters (Reach).,To determine the costs, cost-effectiveness, and budget impact of decentralized swab-based molecular testing with MiniDock MTB as a replacement for sputum smear microscopy at primary health centers (Implementation).,To identify implementation processes and contextual factors that influence the adoption, fidelity, and sustainability of swab-based molecular testing using MiniDock MTB (Adoption; Implementation; Maintenance).,To evaluate the reach and effectiveness of decentralized swab-based molecular testing with MiniDock MTB based on the numbers and proportions of people tested for, diagnosed with and treated for confirmed TB.,
Uganda 2026-10-14 20:06:06 2029-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
A Phase 1b, Observer-Blind, Placebo-Controlled Study to Investigate the Safety and Immunogenicity of mRNA-1469 Vaccine to Prevent Ebola-Bundibugyo Virus Disease in African Participants 1 to 65 Years of Age
REFNo: HS8829ES

Primary 1. To evaluate the safety of mRNA-1469. Secondary 1. To evaluate the humoral immunogenicity of mRNA-1469. 2. To further evaluate the humoral immunogenicity of mRNA-1469. Exploratory 1. To evaluate the cellular immunogenicity of mRNA-1469 in adult participants. 2. To further evaluate the humoral immunogenicity of mRNA-1469. 3. To further characterize the immune response of mRNA-1469.
Uganda 2026-10-14 20:00:08 2029-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Golden Tayebwa Bells
ID: UNCST-2026-R025966
Carbon Market Participation: Economic Viability for Smallholder Coffee Farmers in the Mount Elgon Region of Uganda.
REFNo: A845ES

Overall objective: To assess the economic viability of carbon market participation for smallholder coffee farmers in the Mount Elgon region of Uganda. Specific objectives 1. To estimate the carbon sequestration potential of coffee agroforestry systems in the Mount Elgon region of Uganda using existing field-based studies. 2. To analyze the cost structure of carbon market participation for smallholder coffee farmers in the Mount Elgon region of Uganda. 3. To evaluate carbon market revenue potential for smallholder coffee farmers under different carbon price and aggregation scenarios in the Mount Elgon region of Uganda. 4. To determine the conditions under which carbon market participation is financially viable for smallholder coffee farmers in the Mount Elgon region of Uganda.
Uganda 2026-10-08 17:30:12 2029-10-08 Agricultural Sciences Non-Clinical Trial Degree Award
Ivan Muhwezi
ID: UNCST-2026-R026026
Exploring aflatoxin exposure and antifungal resistance among patients with Chronic Pulmonary Aspergillosis at the Makerere University Lung Institute, Uganda
REFNo: HS8611ES

1. To determine the global Aspergfillus species distribution patterns and antifungal resistance profiles of Aspergillus isolates from patients with CPA
2. To determine the species distribution and antifungal resistance patterns, including underlying resistance mutations, among Aspergillus isolates obtained from CPA patients at the MLI, Uganda
3. To determine the magnitude of biological aflatoxin exposure, measured using serum AFB?-Lys adducts, and which dietary, clinical and demographic factors are associated with this exposure among CPA patients at MLI, Uganda
4. To determine how the MDMs phagocytic capacity and ROS generation associated with serum AFB?-Lys adduct levels and antifungal resistance among CPA patients at MLI, Uganda.
Uganda 2026-10-08 17:28:54 2029-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
Assessment of Lead Contamination, Supply Chains, and Exposure Pathways in Domestic Cookware in Informal Settlements of Kampala, Uganda
REFNo: HS8704ES

1. To analyze and determine the concentrations of total and leachable lead in commonly used domestic cookware types among in informal settlements of Kampala. 2. To map and characterize the cookware supply chain to identify producers and distributors of lead-contaminated products in Kampala. 3.To identify the mechanisms and pathways through which cookware becomes contaminated with lead in Kampala. 4. To identify, document, and prioritize feasible intervention strategies for reducing lead exposure from domestic cookware through stakeholder engagement.
Uganda 2026-10-08 17:25:55 2029-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FLORENCE ALENI GAY
ID: UNCST-2026-R026273
OCCUPATIONAL STRESSORS, PERSONALITY TRAITS, AND JOB PERFORMANCE AMONG ACADEMIC STAFF IN SELECTED PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS5782ES

1. To examine the relationship between challenge stressors and job performance among academic staff in selected public universities in Uganda.
2. To assess the relationship between hindrance stressors and job performance among academic staff in selected public universities in Uganda.
3. To examine the moderating effect of extraversion on the relationship between challenge stressors and job performance among academic staff in selected public universities in Uganda.
4. Assess the moderating effect of neuroticism on the relationship between hindrance stressors and job performance among academic staff in selected public universities in Uganda.
Uganda 2026-10-08 17:23:49 2029-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
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