Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Andrew Gidudu
ID:
Mapping where women in Uganda go to access post- abortion care
REFNo: SS355ES

The overall aim is to gather vital information and map the existing safe, less safe and unsafe post abortion access points and the quality of validated providers who provide services within the law, and PAC service access points in the market, what they offer and where we can fill a service delivery gap. The specific objectives are;
i. To map the location of PAC providers in districts of Uganda where MSI operates centres and social franchisees;
ii. To understand the price of PAC and LAPM services provided in districts of Uganda where MSUG operates centres and social franchises
iii. To understand the safety and quality of PAC services provided in districts of Uganda where MSUG operates centres and social franchisees according to WHO’s safety standards categorize facilities as providing safe, less safe and least safe post-abortion services including mapping and collecting LA/PM pricing from post-abortion providers

Uganda 2019-10-31 2022-10-31 Social Science and Humanities Non-degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
 UNDERSTANDING THE ACCEPTABILITY AND USAGE OF SOFTWARE APPLICATION SYSTEMS DEVELOPED IN HOUSE AT THE INFECTIOUS DISEASES INSTITUTE
REFNo: SIR18ES

The general objective of this proposal is to determine the indicators collected in the IDI software as well as evaluate the functionality of the software systems built in-house at the Infectious Diseases Institute (IDI)
Specific objectives
1) To generate summary and descriptive statistics of the indicators collected using the IDI software (e.g. number and type of trainings organized, number of clients who had SMC by month)
2) To carry out periodic qualitative evaluation of the end user’s satisfaction in order to enable quality improvement of the IDI software
3) To identify the barriers to the usage of the various departmental software systems.

 Uganda 2019-10-31 2022-10-31 Engineering and Technology Non-degree Award
Jacquellyn Nambi Ssanyu Nambi
ID: UNCST-2021-R011827
 Evaluating the effect of empowered Community Health Clubs and a Community Scorecard on Sexual and Gender Based Violence in Mayuge District, Uganda: A quasi-experimental study
REFNo: HS457ES

1.To determine the proportion of women and men who have experienced some form of sexual and gender based violence (SGBV) in the last six months prior the study in Mayuge district.
2.To explore perceptions of community members towards SGBV in Mayuge district.
3.To understand the socio-cultural and economic factors contributing to SGBV in Mayuge district
4.To establish and empower Community health clubs (CHCs) to reduce SGBV in Mayuge district
5.To design and implement an SGBV Community Score Card (CSC) in Mayuge district
6.To determine effect of CHCs and the CSC on SGBV in Mayuge district
Uganda 2019-10-31 2022-10-31 Medical and Health Sciences Non-degree Award
Hilda Ikiriza
ID:
CHARACTERISATION, METABOLITE PROFILING AND MICROPROPAGATION OF INDIGENOUS DIOSCOREA BULBIFERA VARIETIES IN UGANDA
REFNo: NS105ES


i. Establish the Genetic and agronomic variability of Dioscorea bulbifera germ plasm in Uganda

ii. Analyse the secondary Metabolite of antifertility of indigenous Dioscorea bulbfera accessions in Uganda

iii. Develop and validate protocol for Micro-propagation of indigenous Dioscorea bulbifera varieties for increased biomass yield

Uganda 2019-10-31 2022-10-31 Natural Sciences Degree Award
Mercy Tenywa Gladys
ID:
STANDARDIZATION OF DRACAENA STEUDNERI ENGL., AS A REMEDY FOR PAIN RELIEF DURING CHILDBIRTH
REFNo: HS463ES

i)Determine organoleptic and physicochemical parameters of D. steudneri
ii)Determine the safety of D. steudneri by evaluating the acute and sub-acute effects in test animal
iii)Evaluate analgesic and anti-inflammatory activity of D. steudneri
iv)Evaluate oxytocic activity of D. steudneri





Uganda 2019-10-31 2022-10-31 Medical and Health Sciences Degree Award
BYARUGABA ROBERT BYARUGABA NATURINDA
ID:
Investigate the practice of continuous assessment in the teaching of science education: A case study of a Primary Teachers’ College in Uganda.
REFNo: SS371ES

i)To find out how Continuous Assessment practice engages learners in the teaching and learning of science education in Primary Teachers’ Colleges of Uganda?
ii) To investigate the extent to which CA practice in Primary Teachers’ Colleges align with the intended curriculum objectives
 Uganda 2019-10-31 2022-10-31 Social Science and Humanities Degree Award
Jacob Sarfo
ID:
Contribution of processed fruits and vegetables towards sustainable nutrition in East Africa: case study from Uganda
REFNo: A54ES

a) improve the nutrition and health status of consumers – especially women and children b) gauge the knowledge, attitudes and practices of consumers towards fruits and vegetable intake and c) reduce the cost of diet and thus improving affordability.
 Ghana 2019-10-31 2022-10-31 Agricultural Sciences Degree Award
KETTY ANYEKO
ID:
Senses of reparation and justice: women’s decision-making after wartime sexual violence in Northern Uganda
REFNo: SS366ES

To examine the lived experiences of women who were abducted as young girls by the Lord’s Resistance Army rebels and forced to become wives and mothers to children of rebel commanders.

To learn what their senses of justice and reparations are.

To investigate why and how women make decisions on whether or not to reunite with the father of their children born in abduction.
 Uganda 2019-10-31 2022-10-31 Social Science and Humanities Degree Award
Jane Nagayi Yawe Kalule
ID:
THE PHYSIOLOGICAL RESPONSE OF Oreochromis esculentus (Graham, 1929) AT DIFFERENT TEMPERATURE REGIMES
REFNo: NS103ES

1.To evaluate the variation in oxygen consumption of the species populations at different temperature regimes
2.To document how hematological parameters correlation with temperature variation in juvenile O. esculentus.

3. To construe the development of various body organs and their indices proportionate with temperature in juvenile O. esculentus.

4. To characterise the enzymatic activity response to temperature in juvenile O. esculentus.

5. To model the fish production in relation to the global climate change predictions.


 Uganda 2019-10-17 2022-10-17 Natural Sciences Degree Award
Gloria Nduhukire
ID:
Investigating the factors that influence the enrollment of children with physical disabilities in inclusive primary schools in Mitooma district Uganda
REFNo: SS358ES

1. To find out the factors that influence the enrollment of children with physical disabilities
2. To find out the teachers' perception on children with physical disabilities
3. To find out teachers' competences to implement inclusive education in primary schools
4. To find out the perception of parents on educating theri children with physical disabilities
5. To find out the challenges that hinder the enrollment of children with physical disabilities

 Uganda 2019-10-10 2022-10-10 Social Science and Humanities Degree Award
Taddeo  Rusoke
ID:
Evaluating the effectiveness of buffer crops as wildlife crop damage mitigation strategy: A case of crop farmers around Kibale National Park in Uganda
REFNo: A48ES

1. To identify types of buffer crops grown by farmers against specific wildlife to mitigate wildlife crop damage.
2. To establish the effect of wildlife crop damage on yields of major food crops grown around Kibale National Park in absence of suitable buffer crops.
3. To design mechanisms for crop farmers participation in use of suitable buffer crops as a mitigation measure to wildlife crop damage around Kibale National Park.

Uganda 2019-10-08 2022-10-08 Agricultural Sciences Degree Award
Marion de Vevey
ID:
How the presence of friends decreases fear and increases positive emotions: a comparative study between chimpanzees and humans
REFNo: SS351ES

The goal of this study is to analyse the impact of preferred social partners on emotional state in chimpanzees. We want to test whether the presence of a bond partner increases positive emotions when in a positive situation and decreases negative emotions when in negative situations in comparison to a non-bond partner presence. More specifically, fear is expected to decrease with the presence of a friend while joy is expected to increase. A comparison with humans will be done in Switzerland afterwards and therefore will stand on a swiss permit.
 Switzerland 2019-10-08 2022-10-08 Social Science and Humanities Degree Award
Hodaka Kosugi
ID:
Positive deviance for dual-method promotion among women in rural Uganda
REFNo: HS439ES

The objectives of this study are to

(i) examine factors associated with condom use among married women using HECs in an HIV-prevalent setting in Uganda

(ii) identify unique behaviors that are common only among married women who practice dual-method use with their partners

(iii) evaluate an intervention for promoting dual-method use among married women using HECs.

 Japan 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Letha Victor
ID:
Trauma Pollution: an ethnographic and historical theorization
REFNo: SS316ES

The study is part of a larger ethnographic project on the phenomenon of spiritual distress in contemporary northern Uganda, for which I collected the primary data from 2013-2014 (research approved by the UNSCST). This phase of research theorizes how cultural context affects the relationship between psychic trauma (broadly conceived) and ritual pollution (haunting, unwanted spirit possession, unusual illness, misfortune, etc.). The study aims specifically to answer: How do the concepts of "trauma" (in English) and "ajwani" (in Acholi Luo; tentatively interpreted as "ritual pollution) interact discursively? How do contemporary Acholi people interpret the relationship or non-relationship between these two concepts? How have their interpretations changed or not changed since the British colonial (1900-1962) era and the era of humanitarian intervention (2005 to present)? My objective is to examine the connection between "trauma" and "ritual pollution" in 1) current cultural context, by way of observations of and interviews with the Acholi people in Uganda with whom I conducted my primary fieldwork; and 2) by historical examination of the epistemological shifts surrounding ritual pollution and psychic woundedness in Uganda, by way of archival collections on religion and medicalization.
 Canada 2019-10-07 2022-10-07 Social Science and Humanities Non-degree Award
Caroline Namukwaya
ID:
A Pilot Study Exploring the Feasibility of Implementing a Child Development Counseling Program for Caregivers of Children with Sickle Cell Disease (SCD) Aged 0–3 Years in Uganda
REFNo: HS404ES

•To determine whether the Child Development Counselling program is effective in equipping caregivers of children with SCD aged 0-3 years with knowledge and skills that can be used to promote development of their children.
•To explore the experiences of healthcare providers at SCD Clinic at Mulago hospital in delivering a Child Development Counselling Program for caregivers of children with SCD aged 0-3 Years in Uganda.
•To explore the experiences of caregivers for children with SCD aged 0-3 years being part of a Child Development Counselling practiced intervention in Uganda.
•To identify the barriers and facilitators to implementing and delivering an out-patient Child Development Counselling Program for caregivers of children with SCD aged 0-3 Years in Uganda.

 Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Richard Migisha
ID:
Cardiovascular autonomic neuropathy (CAN) among type 2 diabetic patients attending MRRH, Prevalence associated factors and correlation with heart rate corrected QT (QTc) interval.
REFNo: HS413ES

To determine the prevalence of CAN among type2 diabetic patients attending MRRH, SW Uganda
2. To determine the prevalence of QTc prolongation among type 2 diabetic patients attending MRRH, SW Uganda.
3. To assess the relationship between QTc prolongation and severity of CAN in patients with type2 DM attending Mbarara Regional referral hospital, SW Uganda
4. To determine clinical and demographic factors associated with CAN among type2 diabetic patients attending Mbarara Regional referral hospital, SW Uganda

 Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Ziwena Nantongo
ID:
Population structure, genetic diversity and selection signatures in indigenous goat breeds from different agro-ecological zones of Uganda
REFNo: A50ES

1. To characterize the phenotypic diversity of indigenous goat breeds in the different agro-ecological zones of Uganda
2. To clarify the origin of indigenous goat breeds in Uganda
3. To elucidate the genetic diversity of indigenous goat breeds in the different agro-ecological zones of Uganda
4. To identify genetic markers for fecundity among indigenous goat breeds of Uganda
5. To identify selection signatures among indigenous goat breeds in various agro-ecological zones of Uganda

Uganda 2019-10-07 2022-10-07 Agricultural Sciences Degree Award
Robert Kairania
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Masaka Regional mechanism
REFNo: SS334ES

The purpose of the evaluation is to collect data that will inform improvement of program implementation so that services are provided more effectively and efficiently in the region and best practices shared with other IPs in the country. The evaluation will also inform RHSP, CDC and other stakeholders about program challenges, performance gaps, progress towards achievement of set targets and program outcomes (effectiveness) in a timely manner so that implementation strategies can be maintained, scaled up or modified where necessary.
Uganda 2019-10-07 2022-10-07 Social Science and Humanities Non-degree Award
Hedmon Okella
ID:
Screening and Characterization of antimicrobial peptides from fish mucus in three major lakes of Uganda
REFNo: HS449ES

i. Determine the antimicrobial activity of skin mucus from selected fish species obtained from three major lakes of Uganda
ii. Identify the most potent antimicrobial peptides isolated from skin mucus
iii. Evaluate the toxicity of the most potent antimicrobial peptides
iv. Determine the mechanism of action of the most potent antimicrobial peptides

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
TINO OKEDI KEVIN
ID:
OUTCOMES OF END TO END VERSUS OVERLAPPING TECHNIQUES OF REPAIR OF CHRONIC OBSTETRIC ANAL SPHINCTER INJURY, A RANDOMISED CONTROLLED TRIAL
REFNo: HS460ES

GENERAL OBJECTIVE:To compare the outcomes of end to end versus overlapping techniques of repair of chronic 3rd and 4th degree perineal tears in MNRH.
SPECIFIC OBJECTIVES:
i. To compare the proportion of patients with flatal-faecal incontinence 3 months post operatively following repair of chronic third and fourth degree perineal tears with end to end versus overlapping techniques of repair in MNRH.
ii. To compare the proportion of patients with complications; wound breakdown and perineal pain 3 months post operatively following repair of chronic third and fourth degree perineal tears with end to end or overlapping techniques of repair in MNRH.

Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Kemirembe Goretti Maria
ID:
MICROFINANCE SERVICES AND WOMEN’S ECONOMIC EMPOWERMENT IN KYAMUHUNGA PEOPLES’ SACCO.
REFNo: SS361ES

i. To determine the effect of access to microcredit services and selected indicators of women’s economic empowerment.
ii. To determine the relationship between access to financial advisory services and indicators of women’s economic empowerment.
iii. To examine the effect of microfinance savings and selected indicators of women’s economic empowerment.

 Uganda 2019-10-07 2022-10-07 Social Science and Humanities Degree Award
NIGHT MUHINDO PRIMER
ID:
cash management and financial performance of tea processing firms in Bushenyi district. a case of Igara Growers Tea factory.
REFNo: SS364ES

1.To establish the relationship between liquidity management and financial performance of igara growers tea factory
2. To examine the relationship between working capital management and financial performance of igara growers tea factory
3. To show the relationship between financial information management and financial performance of igara growers tea factory.
 Uganda 2019-10-07 2022-10-07 Social Science and Humanities Degree Award
Martin Amanya
ID:
IMMUNOMODULATORY EFFECTS OF ARTAVOL®IN MALARIA PROPHYLAXIS USING A MOUSE MODEL
REFNo: HS465ES

1. To assess the cellular immune response to malaria parasites after treatment with ARTAVOL®
2. To determine the humoral immune response to malaria parasites after treatment with ARTAVOL®
3. To study the effect of crude flavonoids from ARTAVOL® on cytokine production.

 Uganda 2019-10-07 2022-10-07 Medical and Health Sciences Degree Award
Lwanga  Jonathan
ID:
Prediction modelling for Infectious Diseases and Outbreak prevention
REFNo: HS473ES

To determine patterns of flow of outbreaks
 Uganda 2019-09-26 2022-09-26 Medical and Health Sciences Non-degree Award
Serawit Chorito Deyno
ID:
ANTIBACTERIAL EFFECT AND SAFETY OF ESSENTIAL OIL FROM ECHINOPS KEBERICHO
REFNo: HS398ES

1.3. Objective of the study
Major objective
• To evaluate the antibacterial effect and safety of EO from E. Kebericho
Specific objectives
1. To identify and isolate main components of the EO from E. kebericho
2. To determine antibacterial activity of EO and its combined effect with existing antibiotics against S. aureus and P. aeruginosa
3. To determine antibacterial activity of main constituent of EO and its combined effect with existing antibiotics against S. aureus and P. aeruginosa
4. To examine acute and sub-acute toxicity of the EO from E. kebericho

 Ethiopia 2019-09-19 2022-09-19 Medical and Health Sciences Degree Award
Heather Brown
ID:
Evaluating the Impact of a Layperson EMS System on Morbidity and Mortality of Injured Patients in Masindi, Uganda
REFNo: HS414ES

The purpose of this study is to evaluate the effectiveness of a pilot layperson EMS system for commercial boda drivers and the feasibility of using a pre-existing trauma registry to evaluate the outcomes of these patients.

Primary Objective:

Evaluate the impact of a boda driver EMS system on time to presentation for ill and injured patients.

Secondary Objectives:

1. Evaluate the purpose and rate of utilization for a lay person EMS system in Masindi, Uganda.

2. Evaluate the impact of a lay person EMS system on patient morbidity and mortality at MKMC.

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Sona Shah
ID:
Validation of the safety and performance of a clinical vital signs monitor on infants and neonates: A pilot study
REFNo: HS420ES

1. To assess the safety of the Neopenda wearable vital signs monitor (neoGuard) in healthy infants (aged 8 to 16 weeks) and stable neonates (aged 0-28 days)
2. To determine the performance accuracy of neoGuard device in comparison to a gold standard monitor comparable to the Edan M3A Vital Signs Monitor

USA 2019-09-19 2022-09-19 Medical and Health Sciences Non-degree Award
Mary Namubiru
ID:
Meet Your Future Job Search Effort and Aspirations of Young Jobseekers
REFNo: SS338ES

Jobseekers in developing contexts face a number of search barriers to quality employment. The most recurring ones in the literature range from liquidity constraints for travel costs (Abebe et al. 2017a) to high opportunity cost of search-time due to job availability in the informal sector (Franklin, 2017). In addition to these, young jobseekers often do not know how or where to search for jobs, might not understand their skills in relation to what employers want and are likely to have distorted expectations of wage levels and working conditions (Babcock et al. 2012). Importantly, these barriers are magnified right in the most vulnerable phase of a career: the transition into the labor market (Becker 1994, Pissarides 1994). This study seeks to investigate (i) how barriers in access to information affect search efforts, labor outcomes and aspirations of young jobseekers taking their first step in the job market, (ii) how can career-coaching and job search assistance from “the future you” help influencing their expectations and labor market trajectories and (iii) how does the trainees’ degree of identification with “the future you” affect the way in which they interpret somebody else’s experience with respect to their own future. The experimental setting is that of Vocational Training Institutes (VTIs) in Uganda and “the future you” is an alumnus of the VTI, who successfully entered the labor market after receiving the training.
 Uganda 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
Wyatt Brooks James
ID:
Community Lending and Outside Capital (CLOC)
REFNo: SS339ES

To measure the impact of community lending and outside capital on SILC members’ returns and default rate behavior, levels of liquid savings, and change in livelihood.
USA 2019-09-19 2022-09-19 Social Science and Humanities Non-degree Award
Fabien Schultz
ID: UNCST-2023-R008622
 Self-medication in wild chimpanzees and mountain gorillas
REFNo: NS104ES

Observation of novel medicinal plants used for self-medication by wild chimpanzees and mountain gorillas:
The fieldwork at the field stations in Bulindi, Kibale Forest National Park, Budongo Forest Reserve, and Bwindi Impenetrable National Park will result in the documentation of potentially novel medicinal plant species used by great apes in Uganda, which will be reported in our publications.

Comparison between self-medication behavior in chimpanzees at different locations:
The study will generate a comparison between plants and self-medication techniques used by Bulindi chimpanzees (a highly disturbed habitat shared with humans) and Kibale/Budongo chimpanzees (less disturbed habitats).

Impact on modern medicine:
Through this study, we seek to integrate behavioral data with novel pharmacological screenings of plants. Without doubt, the evolution of self-medicative habits from the great apes to early hominids and modern humans has important implications for modern medicine. This project would significantly advance previous research on zoopharmacognosy (or “ape-pharmacognosy”).

Discovery of new plant and insect species and first-time pharmacological investigation of medicinal natural remedies:
I estimate that around 60% of all plant and insect species in the dense rainforests of Western Uganda and Eastern Democratic Republic of Congo remain undiscovered. As such, this project could result in the discovery of novel species, but most likely in the documentation and evaluation of novel medicinal uses in known plants. The majority of plant species used in self-medication by wild chimpanzees and mountain gorillas in the tropical rainforests of Uganda have never been screened for pharmacological activity in a lab or investigated with regard to their chemical composition.

Conservation of biodiversity:
Wild mountain gorillas are classified as Critically Endangered and chimpanzees as Endangered by the International Union for Conservation of Nature. Both great apes are highly threatened by human encroachment, forest degradation, regional political instability and disease. Through our workshop within local communities, we aim to raise awareness of the importance of protecting these creatures as well as local medicinal plants.


Germany 2019-09-19 2022-09-19 Natural Sciences Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 The utility of urine Lipoarabinomannan as a Tuberculosis treatment monitoring tool.
REFNo: HS432ES

To describe the temporal changes of urine LAM during the first 2 months TB treatment of TB-HIV co-infected patients.
To determine the correlation between urine LAM and microbiological response measured by sputum culture among TB-HIV co-infected patients receiving anti-TB treatment.

 Uganda 2019-09-10 2022-09-10 Medical and Health Sciences Non-degree Award
Richard Muwanika
ID:
DEFINING DIAGNOSTIC PERFORMANCE, ANALYTICAL AND OPERATIONAL SUITABILITY FOR POINT OF CARE DEVICES FOR HEMOGLOBIN ESTIMATION DEVICES IN ROUTINE HIV AND MATERNITY CARE IN UGANDA
REFNo: HS437ES

1) To evaluate the analytical performance (accuracy and precision/repeatability) of the available non-investigational Hb POC devices in use in Uganda
2) To evaluate the diagnostic performance (sensitivity, specificity, Positive and Negative Predictive values) of the available Hb POC devices in Uganda
3) To evaluate the operational suitability of the available Hb POC devices in Uganda using a standardized scorecard
4) To determine the operational cost and cost-effectiveness of the available Hb POC devices in Uganda

 Uganda 2019-09-10 2022-09-10 Medical and Health Sciences Non-degree Award
Dunstan Kalanzi
ID:
EXPLORING THE ASSOCIATION BETWEEN PERIODONTAL DISEASE AND THE RISK OF ALZHEIMER’S DISEASE AND RELATED DEMENTIAS: A COMPARATIVE STUDY
REFNo: HS438ES

To determine the periodontal health status of a community-based cohort of elderly persons and factors associated with Alzheimer’s disease and related dementias in Uganda
 Uganda 2019-09-10 2022-09-10 Medical and Health Sciences Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
 Performance of a novel, rapid Neisseria gonorrhoeae genotypic and phenotypic test and estimation of prevalence of 4 STI in a gonococcal surveillance program in Uganda
REFNo: HS455ES

Primary:
• To determine the accuracy (correlation, sensitivity, specificity) of a new mobile, dual purpose gonorrhea point-of-care (POC) STI test device [the Mobile NAAT (MobiNAAT)] against reference laboratory methods for diagnosis (Gram stain and/or culture).

Secondary:
• To determine agreement between self-collected meatal swabs and urine samples for the diagnosis of STI using a gold standard NAATs in Ugandan men (a population with high NG positivity).
• To assess acceptability of self-collected tests in men with UDS in Uganda.
• To validate MobiNAAT for gonorrhoea ciprofloxacin AMR in symptomatic men compared with gold standard (culture & disk diffusion).
• To estimate the prevalence of the following 4 STIs in a population of men with UDS: Chlamydia trachomatis (CT), Neisseria gonorrhoea (NG), Trichomonas vaginalis (TV), and Mycoplasma genitalium (MG) using NAATs.
• To compare sensitivity and specificity of GC NAAT with microscopy and culture in Ugandan samples.
• To assess the prevalence of HIV, syphilis and viral hepatitis, and compare HIV result to self-reported HIV status.
• To explore socio-demographic, behavioural and clinical factors associated with positive STI diagnosis (including NG NAAT-positive and NG culture-negative status).
• Determine the proportion of non-reportable results (unresolved, indeterminate and incomplete).
• Test other STI diagnostics in future on available samples.

Uganda 2019-09-10 2022-09-10 Medical and Health Sciences Non-degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
 High Dose Oral Rifampicin to Improve Survival from Adult Tuberculous Meningitis: A Double-blinded Randomised Controlled Phase III Trial. HARVEST trial
REFNo: HS428ES

Our primary objective is: To determine if high dose rifampicin, delivered orally at ~35 mg/kg/day for 8 weeks, is safe and improves 6-month survival compared to standard of care (rifampicin 10 mg/kg/day) for patients with TBM.
Secondary objectives are to compare the high dose rifampicin regimen to the standard of care regimen for:
1. 12-month survival
2. Neurological disability and functional outcomes from TBM
3. Safety and tolerability
4. Hospital outcomes related to TBM
5. Subsequent neurologic deterioration
6. Management of drug-induced liver injury
Tertiary objectives are to:
1. To describe the pharmacokinetics (PK) of high dose rifampicin in plasma and CSF, assess predictors of exposure to rifampicin in plasma and CSF, assess PK-PD relationships also considering exposures to the other first-line TB drugs and ART in HIV-infected patients, and determine the minimally desired rifampicin exposure for optimal treatment of TBM.
2. To determine the cost-effectiveness of the intervention.
3. To determine appropriate TBM diagnostic algorithms

Uganda 2019-09-05 2022-09-05 Medical and Health Sciences Non-degree Award
Kevin Hunt Dean
ID:
DRY HABITAT CHIMPANZEE ECOLOGY: IMPLICATIONS FOR HUMAN EVOLUTION
REFNo: NS101ES

Document feeding, social and locomotor behavior using 1-minute focal observations. Record food items, ranging behavior, canopy use, feeding rate and habitat use. Collect hairs for trace element analysis. Collect skeletal material from any deceased individuals. Analyze skeletal material for distinctive characteristics. Analyse hormone profiles to determine if lower levels of aggression are due to low T levels. Look for poisons in Muguri River to find source of sex organ abnormalities. Examine dental micro wear and trace elements in hair to determine diet. Look at genetic variations
 USA 2019-09-05 2022-09-05 Natural Sciences Non-degree Award
Sangjin Kang
ID:
Establishment of libraries of indigenous medicinal plants in Mount Elgon area
REFNo: NS86ES

To conserve knowledge and resources about indigenous medicinal plants in Mt. Elgon area through activities such as;

 Republic of Korea Reunion 2019-08-27 2022-08-27 Natural Sciences Non-degree Award
Mushagalusa Kasali Félicien Kasali
ID:
Phytochemical and Pharmacological Study of Chenopodium ambrosioides L. and Physalis peruviana L., herbs used to treat diabetes in Congolese Traditional Medicine
REFNo: HS440ES

1. To test the activity of the bioguided fractions of the extracts obtained in-vivo, on acute, sub-acute and chronic hyperglycemia in experimental rats.
2. To determine the zootechnical, biochemical and histopathological markers of the extracts obtained in experimental rats.
3. To isolate and elucidate the structure of the bioactive components of the extracts obtained.

 Democratic Republic of Congo 2019-08-27 2022-08-27 Medical and Health Sciences Degree Award
Zubair Lukyamuzi
ID: UNCST-2021-R013107
 THE ROLE OF COMMUNITY HEALTH WORKERS IN FACILITATING DISCLOSURE AMONG HIV AFFECTED COUPLES IN GREATER LUWEERO DISTRICT, UGANDA.
REFNo: HS443ES

1. To determine the predictors of non-disclosure among HIV affected couples
2. To document perceptions of HIV affected couples on using CHWs to facilitate their HIV status disclosure
3. To explore CHW’s general and attitudes about HIV status disclosure among HIV affected couples
4. To explore CHW’s experience in facilitating disclosure among HIV affected couples.
5. To determine the proportion of HIV status disclosure among HIV affected couples that can be achieved using CHWs

 Uganda 2019-08-26 2022-08-26 Medical and Health Sciences Degree Award
Christa Kuntzelman Marie
ID:
Refugee Perceptions of their Rights in Uganda
REFNo: SS305ES

The purpose of this study is to learn (a) learn what rights refugees believe they have in Uganda; (b) learn how refugees understand the roles and responsibilities of the Ugandan Government, UNHCR, InterAid, and other NGOs (non-governmental organizations) to provide for refugees in the cities and in the settlements, (c) gain understanding of to whom refugees turn when they need assistance, and (d) understand the role of refugee-led organizations to support other refugees for learning rights or gaining assistance.
 USA 2019-08-20 2022-08-20 Social Science and Humanities Degree Award
Teddy  Kyomuhangi
ID:
Using Digital Stories for Knowledge Translation in Rural South Western Uganda
REFNo: SS318ES

The main objectives of the study are to document evidence-based digital storytelling methods and enhance local capacity to create and disseminate digital stories for knowledge translation in rural southwest Uganda by: 1.Documenting the DST training process so as to contribute towards establishing a model-site offering ongoing mentorship in DST research methodology. 2.Describing experiences of trainees in using DST as a means of disseminating research findings.
 Uganda 2019-08-20 2022-08-20 Social Science and Humanities Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Understanding barriers and motivators to HIV self-testing uptake and clinic linkage among male partners of pregnant women in Uganda
REFNo: HS391ES

Aim 1: To qualitatively elucidate men and women’s personal narratives explaining beliefs, motivations, barriers and experiences influencing clinic HIV testing and linkage to HIV services.

Aim 2: To qualitatively identify attributes of a successful HIVST intervention to increase men’s HIVST uptake and clinic attendance after HIV self-testing. We will assess men and women’s knowledge/perceptions of HIVST and acceptability of strategies to optimize secondary distribution of HIVST from female partners.

Aim 3: To assess healthcare workers perspectives regarding the feasibility and acceptability of potential strategies of secondary distribution of HIVST from pregnant women to their male partners.
Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Non-degree Award
Jorem Awadu Emmillian
ID:
Validation of autism screening assessments: Comparison of the Social Communication Questionnaire, Social Responsiveness Scale and 23-Q with DSM- 5 in assessing for autism spectrum disorder (ASD) in Uganda
REFNo: HS423ES

The study seeks to answer the questions below.
1) In the Ugandan context, do total scores for the three ASD measures (i.e., SCQ, SRS-2, and 23-Q) yield adequate internal consistency relative to values reported in the test manual or available studies for those with ASD?
2) In the Ugandan context, do total scores for the three ASD measures (i.e., SCQ, SRS-2, and 23-Q) yield adequate internal consistency relative to values reported in the test manual or available studies for non-ASD cases?
3) In the Ugandan context, do total scores from the three measures (i.e., SCQ, SRS-2, and 23-Q) yield substantial mean differences consistent with construct-related (i.e., ASD construct) differentiation between ASD and typically-developing groups?
4) In the Ugandan context, will use of the recommended screening cut scores for each of the three measures (i.e., SCQ, SRS-2, and 23-Q) result in adequate sensitivity and specificity using DSM-5 ASD diagnosis vs. typically developing cases as the outcome variable?
5) Beyond the recommended cut scores for screening reported in each test manual, are there more optimal cut scores for each of the three measures (i.e., SCQ, SRS-2, and 23-Q) in the Ugandan context?
6) Are there significant convergent relationships among the total scores of the three measures (i.e., SCQ, SRS-2, and 23-Q) in the Ugandan context?

 Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Degree Award
Andrew  Kalule Owen
ID:
Understanding the implementation process of infection prevention and control guidance at health facility level in Uganda
REFNo: HS424ES

1. To understand how healthcare workers make meaning of IPC guidelines.
2. To understand how healthcare workers make decisions regarding the use of IPC guidelines.
3. To identify factors that influence healthcare workers’ decisions regarding the use of IPC guidelines.
4. To generate a theory to explain the adoption and adaption process through healthcare workers’ ` experiences as IPC guideline users.

Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Degree Award
Teddy  Kyomuhangi
ID:
The adoption of SOPETAR innovations in MNCH service implementation for Bushenyi and Rubirizi Districts.
REFNo: HS427ES

The study seeks to assess the adoption of SOPETAR (scan-orient-plan-equip-train-assess-reflect) innovations so as to identify the high impact components and areas of MNCH services in the existing health structures at the community, health facility, and district levels in Bushenyi and Rubirizi Districts. Specifically, this study aims to: 1) establish the attributes of SOPETAR innovations that were adopted in the existing MNCH services at district health centers in Bushenyi and Rubirizi districts and 2) document how the SOPETAR innovations have been integrated in the MNCH services at district health centers in Bushenyi and Rubirizi districts.
 Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Non-degree Award
WINNIE NAMBATYA
ID:
Risk factors for Neural Tube Defects among children attending Mulago and Kawempe Hospitals: A case control study
REFNo: HS430ES

1. To determine the types of NTDs in Mulago National Referral Hosptial among infants,
2. To determine the factors associate with the NTDs,
3. To compare the factors with the type of NTD

 Uganda 2019-08-20 2022-08-20 Medical and Health Sciences Non-degree Award
Vishakha Vasuki
ID:
Identification of zoonotic gastrointestinal parasites and environmental factors influencing the parasite status of mountain gorillas in Bwindi Impenetrable National Park, Uganda
REFNo: NS102ES

Aim 1: To determine the occurrence and pattern of distribution of parasitic pathogens in mountain gorillas in BINP by non-invasive collection of faecal samples from habituated and non-habituated mountain gorillas. Aim 2: Tracking daily travel patterns using Global Positioning System (GPS) and recording ecological data such as temperature, rainfall, humidity and altitude. Aim 3: Identification of Gastro-intestinal parasites in mountain gorillas using simple faecal floatation technique and agar plate coproculture.
India 2019-08-15 2022-08-15 Natural Sciences Degree Award
Clement Olusoji Ajayi Olusoji
ID:
DEVELOPING PHARMACOPOEIAL STANDARDS FOR AZADIRACHTA INDICA, CYMBOPOGON CITRATUS, MORINGA OLEIFERA, TITHONIA DIVERSIFOLIA AND VERNONIA AMYGDALINA ANTIMALARIAL PLANTS IN UGANDA
REFNo: HS359ES

General Objective is to develop pharmacopoeial standards for the selected Ugandan antimalarial plants.
Specific objectives
1. To determine pharmacognostic, chemical and biological characteristics of the selected antimalarial plants
2. To determine the toxic dose level of the selected antimalarial plants using both acute and sub-acute tests
3. To develop identification and quantification methods for the antimalarial compounds and chemical markers in the plants and
4. To determine and set pharmacopoeial limits for standardization of the antimalarial plant materials

Nigeria 2019-08-15 2022-08-15 Medical and Health Sciences Degree Award
Hayley Roberts
ID:
The Babysitters club: Hormonal regulation of shared infant care in mantled guereza
REFNo: NS94ES

This project seeks to determine the role of key social hormones in the facilitation of non-parental infant care in Colobus guereza. It will determine how important hormones are for the expression of infant care and how oxytocin, vasopressin, cortisol and faecal androgens relate to genetic relationships, infant colouration and observed rates of infant care.
 Australia 2019-08-15 2022-08-15 Natural Sciences Degree Award
Adeline Boatin
ID: UNCST-2019-R001255
 Wireless Physiologic Monitoring in Postpartum Women
REFNo: HS417ES

1. To estimate the clinical effectiveness of wireless physiologic monitoring of women in the first 24 hours after emergency cesarean delivery at Mbarara Regional Referral Hospital (MRRH)
2. To evaluate the clinical adoption of wireless physiologic monitoring at MRRH using an implementation science approach.
3. To use qualitative methods to explore clinical adoption and acceptability of wireless physiologic monitoring among postpartum women at MRRH and understand facilitators and barriers to uptake of wireless physiologic monitoring.
4. To estimate the cost of providing wireless physiologic monitoring of women in the first 24 hours after emergency cesarean delivery at MRRH
5. To estimate the incremental cost-effectiveness, measured as cost per severe maternal outcome adverted using wireless physiologic monitoring compared to current standard of care monitoring.

Ghana 2019-08-15 2022-08-15 Medical and Health Sciences Non-degree Award
Meital Kupfer Tvor
ID:
Representation and Responses: Refugee Voice in Uganda (Note: this has changed in regards to comments from the MAKSSREC)
REFNo: SS344ES

This research aims to change the narrative on humanitarian communications research by focussing on the feedback of beneficiaries – who are the primary subjects in campaigns and photos. This study will employ a qualitative approach, focusing on content analysis and ethnography through structured/semi-structured interviews, surveys, and content analysis, covering three levels: representation, production, and reception (Dogra, 2009). There will be a focus on semiotics (Barthes, 1977), including photo elicitation techniques (Pink, 2009) for individuals in focus group discussions to provide feedback on INGO campaigns.
Primary evidence will come from work with participants in the Refugee Law Project’s (RLP) Media for Social Change (M4SC) Programme, which works in 11 sites across Uganda, including Kampala and the No White Saviors (NWS) organisation, which is an activist Instagram account working to change narratives about the global South.

Data will be focusing on two parts: beneficiary reaction to how refugees are represented in aid campaigns and their utilisation of social media and technology to amplify their own storytelling.

Secondary evidence will buttress this analysis by supporting the narrow case study of Uganda. To ensure quality and feasibility, academic research selection is limited to peer-reviewed journals. Research on this subject encompasses grey literature, academic literature, artistic works, and social media that primarily covers humanitarian emergencies and development campaigns and their relation to the West. Secondary sources derive from relevant literature, as well as INGO campaigns, websites, and social media accounts. Other visual data will be derived from identified grassroots advocacy groups that work to challenge the INGO dominant narrative.

 Germany 2019-08-15 2022-08-15 Social Science and Humanities Degree Award
Catarina Inverso
ID:
From War to Peace as Conflict goes on: Reinventing the state or ignoring it? Assessing the activities of armed groups and informal cross border networks in the borderlands between DRC, Uganda and South Sudan (working title)
REFNo: SS345ES

The objective is to apply the concept of ‘mobility makes the state’ to the notion of state as a framework to answer a central question: How has displacement become a mechanism of South Sudan’s state-making process?
Germany 2019-08-15 2022-08-15 Social Science and Humanities Degree Award
James Ditai
ID:
Maternal and Newborn Health Priority Setting Partnership in Uganda
REFNo: HS444ES

Purpose:
To identify the unanswered questions about maternal health and newborn care from mothers, carers and clinical perspectives in Uganda and then prioritize those that mothers, carers and health workers agree are the most important for the research to address.

Specific objectives:
• To work with mothers, caregivers and health workers to identify uncertainties about maternal health and newborn care in rural Uganda
• To agree by consensus on a prioritized list of those uncertainties, for research in Uganda
• To publicize the results of the Maternal and Newborn Health Priority Setting Partnership in Uganda and process
• To share the results with the ministry of health, academic researchers and funding bodies
 Uganda 2019-08-15 2022-08-15 Medical and Health Sciences Degree Award
Mark  Purdon David
ID:
The Sustainability of International Investment Projects in the Forest and Bioenergy Sectors in Developing Countries: A Comparison of Uganda and Tanzania
REFNo: SS323ES

The objective of this research project is to update research into the sustainability and effectiveness of the foreign investment projects in the land-use sector through a comparative research design involving qualitative and quantitative approaches. Led by Mark Purdon, Assistant Professor at the École des sciences de la gestion at the Université du Québec à Montréal (ESG-UQAM), the project will also involve academic researchers and graduate students at Makerere University in Uganda. In particular, the project will involve Dr. Patrick Byakagaba of Makerere University, School of Forestry, Environmental and Geographical Sciences who has been undertaking similar research over recent years. The specific objective is to determine the extent to which foreign investment projects in the land-use sector in Uganda and Tanzania, which were first investigated in 2009, are contributing to sustainable low-carbon development, with special attention to payment issues, household land management and project performance.
Canada 2019-08-09 2022-08-09 Social Science and Humanities Non-degree Award
Rosemary Nakijoba
ID:
The Inter-relationship between Gender, Child Labour and Disability among War Affected Communities of Northern Uganda
REFNo: SS113ES

Objectives of the Study The study is guided by a general objective, subdivided into six specific objectives. General objective The study intends to explore the relationship between gender, child labour, disability and the well-being of children in war affected communities of Northern Uganda. Specific Objectives The study will be guided by the following objectives: 1.To explore participants’ perceptions on the concepts of gender, child labour and disability among war affected communities of Northern Uganda. 2.To document gender differences that exist in child labour in war affected communities of Northern Uganda 3.To document differences in child labour practices that exist between the war affected disabled and non disabled children in communities of Northern Uganda 4.To examine the cultural beliefs and practices on children with disability in war affected communities of Northern Uganda 5.To explore the existing interventions on disability for children in war affected communities of Northern Uganda. 6.To develop an explanatory theory that links gender, child labour, and disability for the well being of children in war affected communities guiding intervention processes
Uganda 2019-08-06 2022-08-06 Social Science and Humanities Degree Award
Japheth Kwiringira Nkiriyehe
ID: UNCST-2019-R000408
 A Livelihood-Sanitation Nexus: Implications for Sustainable Slum Sanitation in Urban Uganda
REFNo: SS273ES

Main Objective
To explore the role of livelihoods in sustainable slum sanitation in Uganda
Specific Objectives
1. To describe the livelihoods of shared latrine users across three (3) major urban areas in Uganda
2. To relate various slum livelihoods with sanitation demand and supply.
3. To identify which livelihoods play a positive function in maintaining shared slum sanitation

Uganda 2019-08-06 2022-08-06 Social Science and Humanities Non-degree Award
Daniel Shephard
ID:
Resilient Learners, Teachers, and Education Systems in Uganda: An Exploratory Study
REFNo: SS280ES

There are two overarching research questions in this exploratory study:
1. How do instructors participating in the AVSI-Oxfam program in Palabek, Uganda conceptualize well-being and resilience?

2. How do young people who are currently participating (or may eventually participate) in the AVSI-Oxfam program in Palebek, Uganda conceptualize well-being and resilience?

a) To begin exploratory research about how learners and teachers conceptualize well-being and resilience in contexts of displacement.
b) To learn more about project interventions, especially accelerated education (AE) and teacher education and professional development (TEPD) through key informant interviews and observations.
c) To gain insights about the larger context and operational space in Palabek settlement.

USA 2019-08-06 2022-08-06 Social Science and Humanities Non-degree Award
Robert Kairania
ID:
TESTING HIV SUSCEPTIBILITY IN FORESKIN TISSUE
REFNo: HS372ES

Study objective: To explore potential determinants of HIV infection in foreskin tissue.
Aim 1: Explore host immune factors that contribute in vitro HIV infection.
Aim 2: Explore microbial factors that contribute in vitro HIV infection.
Aim 3: Explore viral factors that contribute in vitro HIV infection

 Uganda 2019-08-06 2022-08-06 Medical and Health Sciences Non-degree Award
Matthew Henderson George
ID:
Chimpanzee communication and its function in the regulation of fission-fusion social dynamics
REFNo: NS92ES

- Enhance overall understanding of gestural and vocal communication of East Africa Chimpanzees with a focus on the understudied female sex
- Understand how female chimpanzees use short-distance gestures with their infants and long-distance vocalizations to maintain fission-fusion dynamics
- Which gestural or postural markers are used by females and their infants specifically before joint travel
- What behavioural cues produced by infants and mothers differ prior to successful joint travel of all forms
-How behavioral context affects the pant-hoot structure in female chimpanzees
- How individual life-characteristics differences affect pant-hoot vocalizations
 USA 2019-08-06 2022-08-06 Natural Sciences Degree Award
Kananura  Muhumuza Rornald
ID: UNCST-2019-R000239
 Child health and survival in Central Eastern Uganda
REFNo: HS395ES

The objectives of the study are to: examine maternal and neonatal mortality social and institutional drivers in central eastern Uganda; and establish the role of public authority in shaping maternal and child health in central eastern Uganda.
Uganda 2019-08-06 2022-08-06 Medical and Health Sciences Degree Award
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