Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Solomon Nsumba
ID:
Intelligent wearable systems for detecting medication errors at CoRSU Rehabilitation Hospital
REFNo: SIR360ES

To design and implement a low-power, real-time wearable system that seamlessly integrates with existing medical equipment, facilitating continuous monitoring and detection of medication errors during surgical procedures.,To prototype a software system capable of providing real-time feedback to medical personnel and generating automated records based on detected medication errors, integrating insights from the developed computer vision models.,To develop advanced computer vision models tailored to accurately detect and classify drug delivery events and associated errors, leveraging insights from the curated dataset,To curate a comprehensive video/image dataset capturing diverse medical drug events and errors in real-time during surgical procedures.,Overall Goal is to develop machine learning models that can detect medical drug events and errors in real-time during surgery.,
Uganda 2024-07-10 13:29:17 2027-07-10 Engineering and Technology Non-Clinical Trial Degree Award
Kristen Little Marie
ID:
Exploring the Non-Hormonal and On-Demand Contraceptives Value Propositions: Perspectives from End Users, Private Sector Healthcare Providers, and Stakeholders in Kenya, Nigeria, and Uganda
REFNo: SS2745ES

: To understand the benefits, challenges, and preferences for the on-demand pill, including product naming and framing, and perspectives on a standalone vs. EC+ on-demand pill, among potential end-users. Sub-aims: 1.) To explore women’s perceptions regarding non-hormonal contraceptives (relative to hormonal options) and their stated preferences for product attributes including dosing schedule, side effects, and benefits; 2.) to describe women’s current use of emergency contraceptive pills, including routine, regular, or repeated use of ECPs, and these users’ perspectives on a potential on-demand pill product.,To understand motivators and barriers and support required for private healthcare providers (HCPs) to consider stocking/selling the LNG 1.5 on-demand/pericoital contraceptive pill. Sub-aim: To understand provider perspectives on the value of and barriers to a weekly, non-hormonal pill in the private sector.,Explore the acceptability of on-demand and non-hormonal contraceptives among private providers, user preferences for on-demand and weekly non-hormonal products among adult women, and key informants and market actors to inform clinical trial pathway decisions and product positioning,
USA 2024-07-10 13:28:15 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Mathuva
ID:
Transforming Social Ministries into Sustainable Social Enterprises by the Religious Sisters in the Catholic Church
REFNo: SS2158ES

The purpose of this study is to contribute to the body of knowledge on the work of Catholic sisters as they seek to transform their social ministries and charities into sustainable social enterprises.
Kenya 2024-07-10 13:25:42 2027-07-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
Clinical Equivalence Validation of the ANC panel (professional use)
REFNo: HS4369ES

The primary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against the individual DetermineTM tests based on a) finger-stick samples and b) venous whole blood samples.
The secondary objectives of this study are:
• To evaluate the equivalence of the ANC panel test results based on a finger-stick sample against laboratory-based reference testing.
As a secondary objective, a user experience questionnaire will also be completed by each professional test user
UK 2024-07-10 13:24:19 2027-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Marvin Kadigo
ID: UNCST-2024-R004323
Perspectives and preferences of both refugees and hosts on refugee local integration in Uganda
REFNo: SS2797ES

The main objective of the study is to comprehensively evaluate the perspectives and preferences of both refugee and host populations regarding the local integration of refugees within Uganda.To determine the average preference of both refugees and hosts (Ugandans) for the different integration scenarios
Uganda 2024-07-09 18:43:00 2027-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Harold OGWAL
ID: UNCST-2024-R005378
EFFECTS OF WETLAND SPATIO-TEMPORAL CHANGES ON WATER QUALITY AND SEDIMENTS, A CASE OF OKOLE WETLAND IN LIRA CITY.
REFNo: NS815ES

To explore the socio-ecological and economic drivers associated with wetland degradation within Lira City ,To examine the effect of wetland changes on the sediment concentration of the wetland systems within Lira City ,To evaluate the impacts of wetland degradation on the water quality of the identified wetland systems within Lira City,To conduct spatio-temporal analysis of wetland changes between 1999 and 2023 within Lira City,To study the effects of Okole wetland spatiotemporal changes on water quality and sediments within Lira city,
Uganda 2024-07-09 18:37:28 2027-07-09 Natural Sciences Non-Clinical Trial Degree Award
Nsobya  Samuel
ID: UNCST-2021-R012265
Ex vivo characterization of the drug susceptibility of malaria parasites in Uganda (Ex vivo study)
REFNo: HS4481ES

Primary objective
1. To characterize the ex vivo drug susceptibility of P. falciparum isolates collected from multiple sites in Uganda.
Secondary objectives
1. To characterize mutations that mediate drug resistance in P. falciparum isolates collected from multiple sites in Uganda
2. To characterize mutations that mediate drug resistance in banked P. falciparum previously collected from multiple sites in Uganda.
3. To culture, adapt and store P. falciparum isolates to enable studies of mechanisms of antimalarial drug resistance.
4. To measure drug levels in serum or plasma to help to understand treatment responses.

Uganda 2024-07-09 18:35:24 2027-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Diana Namumbejja Abwoye
ID:
Preventive medicine for displaced persons/refugees residing in Palabek settlement
REFNo: SS2818ES

To understand the experiences of refugees in Palabek resettlement with preventive healthcare through in-depth interviews,To explore knowledge, beliefs and attitudes of preventive healthcare among refugees living in Palabek resettlement through in-depth interviews, The long-term goal is to obtain a deeper understanding of how refugees living in Palabek resettlement camp perceive and utilize preventing medicine and inform stakeholders in the camp of any gaps or needs that may improve access and care. It is imperative to understand refugees’ perceptions and experiences with preventive medicine and establish which aspects of their refugee experience may influence utilization of preventive healthcare when available.,
USA 2024-07-09 18:33:18 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
The impact of the World Food Program (WFP) indirect conditional contracts
REFNo: SS2800ES

The research seeks to assess the impact of WFP's indirect conditional contracts on (maize) value chain outcomes such as access to reliable markets, value chain transformation and upgrading, welfare of the participating actors, and the scalability of the policy.
Belgium 2024-07-09 18:28:29 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
Assessing community drug distributors’ participation in the river blindness program currently undergoing mass treatment: A case study of Kasese, Kitgum and Adjumani districts in Uganda
REFNo: SS2838ES

propose recommendations for improving/enhancing CDDs’ involvement and participation in RB programs for its future sustainability.,To assess communities’ perspectives about using CDDs during MDA. ,To establish whether the CDDs are needed to implement the MDA program and identify key stakeholders involved in the program at the community level.,To examine the facilitators and barriers to CDDS’ involvement and participation in the program. ,To explore the experiences and perspectives of the CDDs regarding their participation in the RB MDA program,To Identify the proportion of CDDs that have been selected and trained and those that have participated in the RB MDA program. ,The main objective of this study is to assess CDDs’ participation in the RB program activities in three selected districts currently undergoing mass treatment in western and northern Uganda to guide the review of existing programs or develop new ones altogether, to improve the CDDs’ future involvement and participation in MDA programs,
Uganda 2024-07-09 18:26:45 2027-07-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
Implementing oral (event-driven and daily) and long-acting Pre-exposure prophylaxis (PrEP) in mobile men in Sub-Saharan Africa: a phase 3b, open-label, hybrid type 2 implementation and effectiveness trial (MOBILE MEN)
REFNo: HS4366ES

Overall Objective
To assess effectiveness and implementation of long-acting cabotegravir (CAB-LA) and oral Truvada (both daily and event driven) through comparison of uptake, retention in care, coital coverage, and participant choice.
Uganda 2024-07-02 15:08:06 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Kiconco Prisca
ID: UNCST-2023-R005626
HUMAN RESOURCE MANAGEMENT IN RELIGIOUS INSTITUTES IN UGANDA
REFNo: SS2769ES

To create awareness among the religious, basing on the fact that religious institutes have qualified, skilled and capable members who when distributed rightfully to different fields, there is possible production of effective results. ,To provide help to other religious institutes and other consecrated persons in and beyond Uganda as a resourceful material they can rely on as they manage human resource of the institute (s).,To establish the degree at which religious Institutes in Uganda are effectively managing their human resources for the benefits of the Institute and that of the Universal Church.,
Uganda 2024-07-02 13:42:13 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Faustino Byanyima
ID: UNCST-2024-R004003
Establishing the Effect of Financial Literacy on Financial Products Utilisation: a Case Study for Youth and Women Small Medium Enterprises in Southwestern Uganda.
REFNo: SS2660ES

Main Objective
The main objective of the study is to examine the effect of financial literacy on financial products utilisation among youth and women SMEs in Southwestern Uganda.

Specific Objectives
1. To determine the level of financial literacy among youth and women SMEs in Southwestern Uganda.
2. To identify the financial products used by youth and women SMEs in Southwestern Uganda.
3. To investigate the challenges and opportunities of financial product utilisation among youth and women SMEs in Southwestern Uganda.

Uganda 2024-07-02 13:40:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Racheal Nalunkuma
ID: UNCST-2020-R014616
Effect of the Facility-Based-Group-Model of the Differentiated Service Delivery on Stigma and Antiretroviral-Therapy-Adherence among Adolescents Living with Human-immunodeficiency-Virus in Central Uganda.
REFNo: HS4373ES

1. To evaluate the effect of the FBG model on ART Adherence among ALHIV in Central Uganda, comparing urban and rural HIV clinics from 2016 to 2023.
2. To determine the level of stigma among ALHIV under the FBG Model in Urban versus Rural HIV Clinics in Central Uganda.
3. To explore lived experiences towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.
4. To explore Peer leaders and Healthcare workers’ perception towards the FBG Model in reducing HIV-associated Stigma and enhancing ART adherence among ALHIV in Urban and Rural HIV Clinics in Central Uganda.

Uganda 2024-07-02 13:39:27 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Donald Kugonza Rugira
ID: UNCST-2021-R013291
From Project to Program-based Extension Service Delivery: Assessment of the Impact of Interventions Implemented by the Centre for Sustainable Rural Livelihoods Program in Kamuli, Uganda
REFNo: A434ES

• Analyze the model/s and approaches used when delivering agricultural extension programs in Kamuli. • Identify farmers' perceptions of the effectiveness of the various agricultural technologies? used under the ISU-UP. • Identify clients' descriptions of effective and impactful agricultural and agricultural extension programs. • Capture and document clients’ success stories as a result of participating in the ISU-UP. • Capture donors' and program managers' perceptions of the agricultural and agricultural extension programs.
Uganda 2024-07-02 13:38:11 2027-07-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Bernard Omech
ID: UNCST-2020-R014820
Baseline characteristics and development of an integrated chronic disease care model for diabetes and hypertension management at primary healthcare facilities (ICDC)
REFNo: HS4285ES

To co-design an integrated chronic Diseases care model for management of hypertension and Diabetes mellitus through a participatory process to inform future intervention studies in Lango sub-region ,To examine the knowledge and practice of health care providers towards integration of chronic care for Hypertension and diabetes at selected PHC facilities in Lango sub-region ,To assess the patient’s perception of integration of chronic care for hypertension and diabetes mellitus among patients among patients attending selected primary health care facilities in Lango sub-region ,To determine baseline profiles (HBA1C levels, BP levels, QoL) of patients with hypertension and diabetes mellitus attending outpatient clinic at selected Primary health facilities in Lira City and District ,To evaluate baseline characteristics and develop a model of integrated chronic Disease care for management of hypertension and diabetes at primary health care in Lango Sub-region, Northern Uganda,
Uganda 2024-07-02 12:56:36 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
INVENTORY, EFFECTIVENESS, AND SAFETY OF NOTIFIED NATURAL MEDICINES FOR THE TREATMENT OF DIABETES IN UGANDA: A PROSPECTIVE OBSERVATIONAL STUDY. A CONAT PROGRAM
REFNo: HS4356ES

The general objective is to create an inventory of NDA-notified natural or herbal medicines commonly used in the management of diabetes in adult patients in Uganda, and evaluate their preliminary effectiveness and safety Specific objectives are: 1. To establish the NDA-notified natural or herbal medicines commonly used in the management of DM among adults in Uganda 2. To determine the preliminary effectiveness of the NDA-notified natural or herbal medicines in lowering blood glucose levels when used in isolation or as complementary to conventional DM medicines 3. To assess the effect of the NDA-notified natural or herbal medicines on specific cardiometabolic characteristics of adult patients with DM in Uganda, when used in isolation or as complementary to conventional DM medicine 4. To determine the safety profile of the NDA-notified natural or herbal medicines when used in isolation or as complementary to conventional DM medicine in adult patients in Uganda
Uganda 2024-07-02 12:54:13 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
ENHANCING PATIENT TRIAGE FOR NEUROSURGICAL CARE: A MIXED METHODS APPROACH
REFNo: HS4184ES

3. To design a patient triage model that accounts for criticality, resource availability, and healthcare costs.,2. To determine the key factors affecting patient triage decisions in neurosurgical care.,1. To assess the current patient triage system in neurosurgical care and identify its strengths and weaknesses.,The general objective of this research is to assess the current patient triage system in neurosurgical care, identifying its strengths and weaknesses in Uganda and Nigeria. ,
Uganda 2024-07-02 12:52:48 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elliott Collins
ID: UNCST-2024-R005211
Measuring the Impact of Group Loans and Digitized Ledgers on Savings Group Participants in Uganda
REFNo: SS2731ES

Measure the impact of savings group ledger digitization on savings group efficiency, savings behavior, and social cohesion.,Measure the impact of FAST loans on savings group participants’ access to financial services and livelihood outcomes.,
USA 2024-07-02 12:50:51 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Mpendo
ID: UNCST-2024-R004147
Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition
REFNo: HS4092ES

• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Number and characteristics of new HIV infections, including detection of resistance to CAB while on study. Secondary.
Secondary Objectives
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Incidence and severity of serious adverse events, Grade 3 and Grade 4 ISRs, and any clinical or laboratory adverse events leading to discontinuation of CAB while on study.

Uganda 2024-07-02 12:49:10 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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