Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Olak Ongaya Denis
ID:
Scaling-up innovative Gender, Inclusion and Safeguarding Approaches: Evidence from Malawi, Uganda and Ethiopia
REFNo: SS2919ES

• Strengthen capacities of education managers at all levels to identify and address bottlenecks in the delivery of equitable and quality education at the school level.,• To Mobilize knowledge on optimal use of school-based data for education decision-making, policy and management amongst education stakeholders.,• To gather and develop guidelines on best practices of scale-up, which will be adopted and resourced by the government to develop capacity, influence, and improve education policy and practice on scale-up of GEI interventions,• To generate knowledge that contributes to a broader understanding of the factors of scale-up to guide stakeholders, including policymakers and other researchers on future GEI education interventions and scale-up strategies. ,To contribute to the understanding and improvement of scale-up practices of GEI-focused education projects at local, regional, and international levels.,
 Uganda 2024-09-04 12:57:16 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Katende
ID:
Characterization of New Childhood HIV Infections in USAID supported regions in Uganda (NCHiS)
REFNo: HS4857ES

The assessment aims to characterize those children newly diagnosed with HIV in terms of their demographics, geography, access to care, care continuum and social determinants, to inform child HIV services on targeted and effective case finding and treatment services that can support the reversal of sub-optimal case finding and viral load suppression, and the stagnation in the overall rate of new vertical infections.
a. Primary objective
To describe the determinants or associated risk factors of persisting vertical HIV infections among children.
b. Secondary objectives
i. To report on the perspectives of key stakeholders on the utilization of child HIV services from implementor to the recipient.
ii. To describe the distribution of HIV seropositive children by HIV acquisition mode e.g., vertical MTCT (PMTCT and non-PMTCT), BF, through sex, trauma/GBV.
iii. To establish the proportion of uniquely identified HIV seropositive children in the survey region.

 Uganda 2024-09-04 11:10:19 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Understanding the causes of deaths amongst persons with Rheumatic Heart Disease in Uganda
REFNo: HS4663ES

Main objective: To identify the causes of death among RHD registrants in the National RHD registry in Uganda
 Uganda 2024-09-02 15:12:28 2027-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Babirekere Iriso
ID: UNCST-2024-R005372
 International Investigation into the Genetics of Severe Acute Malnutrition in Children
REFNo: HS4569ES

Determine the contributions of genetic markers to the development of ESAM vs NESAM and its clinical characteristics Elucidate the role of epigenetic mechanisms in the development of ESAM vs NESAM
 Uganda 2024-08-30 15:11:38 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Larison Jean
ID:
Investigating the Genetic Causes of Malformed Stripe Patterns in Plains Zebras
REFNo: NS831ES

Our primary objective is to understand the causes (specific genes, low heterozygosity) of abnormal striping in plains zebras

Specific Objectives:
1. Collect samples from both individuals with abnormal striping and normal striping in order to discover the genes associated with the various forms of abnormal striping

2. Use these same samples to further assess the potential relationship between aberrant striping and genomic heterozygosity
 USA 2024-08-30 15:05:53 2027-08-30 Natural Sciences Non-Clinical Trial Non-degree Award
Barnabas Bakamutumaho
ID: UNCST-2021-R012636
 MULTIDIMENSIONAL AND LONGITUDINAL IMMUNE PROFILING OF SEPSIS IN UGANDA
REFNo: HS4546ES

General Objective:
The overall goal of this project is to stratify sepsis patients in Uganda into biologically driven and therapeutically relevant subtypes.
Specific Aims/Objectives:
(1) Establish pathobiologically-driven and clinically meaningful sepsis endotypes in Uganda
(2) Define longitudinal immune response trajectories associated with sepsis-related death and disability
(3) Determine immune cell phenotypes and function unique to sepsis in persons living with HIV (PLWH).

Uganda 2024-08-30 15:04:57 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Akankwasa
ID:
Evaluation of the Comprehensive and Inclusive Disability Prevention Project in Nakaseke and Nakasongola Districts.
REFNo: SS2991ES

• To establish the extent to which the CIDP project has built the capacity of formal and informal structures to facilitate comprehensive and inclusive disability programming in the two districts of Nakaseke, Nakasongola.
• To assess the degree to which the CIDP project has provided quality, comprehensive and inclusive disability prevention services with focus on primary, secondary and tertiary prevention in the two districts of Nakaseke, Nakasongola
• Determine the extent to which the CIDP project has strengthened participatory advocacy, social protection, and poverty reduction through community-driven innovations in the two districts of Nakaseke, Nakasongola
• To assess the impact of the CID project on the evidence base on comprehensive Disability programming through action research, monitoring, evaluation and learning.

 Uganda 2024-08-30 14:56:58 2027-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lisa Dulli
ID: UNCST-2024-R004307
 Community-based mentorship for out-of-school youth in Adjumani and Buyende Districts, Uganda: An implementation research study
REFNo: SS2789ES

a secondary objective we will document the experiences of youth mentoring program participants who seek SRH services within the community, and their perspectives with regard to the quality and responsiveness of the services to their needs.,the study’s primary objective is to examine key aspects of implementation for the SHARE project mentoring activities targeting AGYW and ABYM, including reach, effectiveness, adoption, implementation, maintenance (including cost), and external and internal (organizational) contexts in two settings.,
 USA 2024-08-30 14:55:02 2027-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Bibangambah Mulungi Nabatanzi
ID: UNCST-2024-R004669
 Assessing the awareness and understanding of Duchenne Muscular Dystrophy among health workers and community members in Uganda.
REFNo: HS4766ES

Evaluate the impact of health education awareness drive program on mitigating the knowledge gap of DMD among health workers and the community(s) in Uganda. ,To ascertain the Prevalence of Clinical Duchenne Muscular Dystrophy in Uganda. ,To assess the knowledge gaps of Duchenne Muscular Dystrophy among health workers and the various community members in Uganda.,The overall goal of the research is to assess the knowledge, insight, and perception of DMD among health workers and the community. ,
 Uganda 2024-08-29 18:54:13 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Kalenzi
ID:
Succession planning factors, transition process and the continuity of small and medium-size family businesses in Fort Portal City Uganda
REFNo: SS2862ES

i. To examine the influence of internal succession planning facets on family business continuity in Fort Portal Tourism City, Uganda. ii. To assess the influence of external succession planning facets on family business continuity in Fort Portal Tourism City, Uganda.
iii. To investigate the mediating influence of succession process (transition) on the relationship between succession planning facets and family business community in Fort Portal Tourism City.

 Uganda 2024-08-29 18:50:55 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
 ASSESSMENT OF CARDIOVASCULAR DISEASE (CVD) POLICY IMPLEMENTATION IN UGANDA - DEVELOPMENT & OPTIMIZING A POLICY MONITORING TOOL USING ROUTINE HEALTH DATA
REFNo: HS4649ES

1.To characterize CVD policy environments and identify the data-specific determinants of policy design and implementation in Uganda a. Specifically, we will use hypertension policy as an example condition to trace the policy processes in each country. Aim 1 has two components:

2.To develop a CVD policy monitoring tool that uses routine health data in Uganda to CVD policy implementation at health center level II & III.

3. To develop a proof-of-concept policy modeling tool that links routine health data to policy analysis in Uganda.

 Uganda 2024-08-29 18:49:22 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Roos Derrix
ID: UNCST-2023-R005749
 The multi-levelled politics of national refugee policies: A case study of Uganda MUST-2024-1373
REFNo: SS2616ES

Given the problem statement the specific aim of this research is to create a multi-level framework to study power relations in refugee policy in countries of first asylum by using Uganda as a case study (specific). I consider conducting such a study meaningful in two ways (meaningful): 1) Scientifically, it will advance literature on International Relations and Refugee studies by adding a perspective from the Global South and directly linking policies that are shaped on a (inter)national level – and that are the outcome of political debate – to their implementation on the ground. 2) Looking into this topic is societally meaningful as it looks at the effect of policies on the lives of refugees and problems that can be found in the current system. In order to fulfil these objectives, I will conduct interviews with actors that make/influence/implement policies and refugees, the actors that are ‘receivers/co-creators’ of these policies. To conduct the interviews I will travel Kampala and refugee settlements Nakivale and Adjumani. It will also help me to travel to New York, Geneva, and Brussels to conduct interviews with policy makers at (mainly UN) institutions (action-oriented). I will be able to do this since I can use my personal travel fee (provided by the Research Foundation Flanders on an annual basis) for travel but also for payment of renumeration of participants and research assistants. If that amount is not sufficient, I can apply for a travel grant with the same organisation. To ensure that I have the right skills to conduct these interviews, I have followed trainings (realistic). ,
 Netherlands 2024-08-29 18:47:09 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
 Use of Large Language Models to Scale Training for Rheumatic Heart Disease Screening Among Primary Care Nurses in Uganda
REFNo: HS4775ES

Our objectives are to create and implement a novel technology to train end-users (i.e., Ugandan primary healthcare nurses) to conduct rheumatic heart disease (RHD) screening echocardiograms, to assess the efficacy of this novel technology-based training approach against the currently employed training methodology, and to understand barriers and facilitators to its adoption among targeted end-users.
Uganda 2024-08-29 18:46:02 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stavia Turyahabwe Stavia
ID: UNCST-2022-R011373
 Field Performance Evaluation of the Point of Care Afinion C-Reactive Protein for TB screening in People living with HIV
REFNo: HS4825ES

a) To compare the performance of CRP, WHO 4 SS (ICF guide) and the CXR in screening for TB in PLHIV b) To determine the performance characteristics of CRP as a screening test for TB among AHD patients against TB LAM as a TB reference diagnostic tool c) To determine the performance characteristics of CRP as a screening test for TB among PLHIV against Xpert MTB/RIF-ultra as a TB reference diagnostic tool. d) To determine the feasibility of integrating CRP into TB screening algorithm for PLHIV in a high TB/HIV burden setting. e) To determine the cut-off threshold of CRP in screening of TB among PLHIV in a high TB/HIV burden setting
 Uganda 2024-08-29 18:44:02 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kamoga Ronald
ID: UNCST-2019-R001524
 ASSESSMENT OF ADHERENCE TO A MEDITERREANAN DIET AND CHALLENGES ASSOCIATED WITH FEEDING PEOPLE HAVING MILD TO MODERATE DEMENTIA IN SOUTH WESTERN UGANDA.
REFNo: HS4404ES

To determine the barriers and facilitotors of adherence adherence to a mediterranean diet among people living with dementia and those at risk of dementia in southwesten Uganda,To determine the level of adherence to a Mediterranean diet among people with dementia and those at risk of dementia in southwestern Uganda,1) To determine the types of diet and dietary pattern of people with dementia and those at risk of dementia in southwestern Uganda,To assess types of diet, dietary patterns, adherence to mediterranean diet and associated factors in people living with mild to moderate dementia and those at risk of dementia in Southwestern Uganda ,
 Uganda 2024-08-29 18:42:48 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Milton Musaba Wamboko
ID: UNCST-2019-R000825
 Effectiveness and Safety Dosing of Sodium Bicarbonate in Women with Obstructed Labor in Eastern Uganda: A Phase III Randomized placebo-controlled Trial (SoBicOL- II Study)
REFNo: HS3885ES

General objective
To determine the efficacy and safety of a preoperative infusion of sodium bicarbonate on pH and lactate levels (metabolic acidosis) among women with obstructed labour.
Specific objectives
1. To determine the efficacy of a preoperative infusion of sodium bicarbonate on acidosis, compared with placebo among women with obstructed labour (OL).
2. To determine the safety of a preoperative infusion of sodium bicarbonate compared with placebo among women with obstructed labour (OL).

 Uganda 2024-08-29 18:40:41 2027-08-29 Medical and Health Sciences Clinical Trial Non-degree Award
Elizabeth Nyboer Ann
ID: UNCST-2023-R005929
 Building resilience to climate change in Lake Victoria’s fisheries: the role of women’s fisheries organizations in Uganda.
REFNo: SS3103ES

The broad goal of this project is to understand factors that have led to successful adaptation outcomes for women involved with Womens Fisheries Organizations (WFOs), and to document WFOs’ potential to facilitate long term climate resilience in Uganda’s fisheries. Objective 1 (O1) is to establish indicators of success from the perspective of the women involved in WFOs. Objective 2 (O2) is to document actual livelihood and adaptive outcomes of being involved in WFOs (based on indicators from O1). Objective 3 (O3) is to document (a) qualitative factors relating to social dynamics, governance structure, and power relations and (b) quantitative spatial, infrastructural, ecological, and demographic measures that have contributed to WFO success.
 Canada 2024-08-29 18:38:08 2027-08-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Tuhame Kamondo
ID: UNCST-2023-R007632
 Tackling Youth Unemployment: Aligning University Training to Industry Skills Demand through a University-Industry Communication Model
REFNo: SIR359ES

Implement the communication model and initiate a pilot phase within selected departments to assess its viability and effectiveness.,Design an integrated University-Industry Communication model tailored to the identified needs and gaps.,To analyze the existing collaborations between academia and industry, identify strengths and improvement areas.,To Conduct a comprehensive baseline survey to ascertain current and anticipated industry needs/skill demands and the university course curriculum development process.,To develop a technology-enabled university-industry communication model implemented in a web portal aimed at narrowing the mismatch between required industry skills and the quality of university graduates. This will collate industry and university needs into a repository to inform training curricula, programme design, research agenda, funding opportunities and skills gaps.,
 Uganda 2024-08-29 18:37:17 2027-08-29 Engineering and Technology Non-Clinical Trial Non-degree Award
Claire Arinaitwe
ID:
Towards Building The Capacity Of Digital Immigrant University Teachers For The Effective Delivery Of Online Learning
REFNo: SS2870ES

3. What factors should be considered in formulating a framework for implementing tailored capacity building initiatives of university teaching staff in Uganda? ,2. What challenges do university teaching staff encounter when embracing digital teaching methods in Uganda?,What are the current digital literacy levels among university teaching staff in Uganda?,The general objective of this study is to find ways to build the capacity of digital immigrant university teachers for effective delivery of online learning,
 Uganda 2024-08-29 18:36:20 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
Evas Kemigisha
ID:
Investigating the potential of integrating community governance arrangements in maternal health care service delivery in Uganda: opportunities, challenges and lessons for multi-level governance
REFNo: SS2905ES

To explore ways in which local knowledge and practices on maternal health can be integrated into maternal health service delivery in Bwindi community and inform multi-level governance actors,To document the daily maternal health knowledge, practices and perceptions of local women about community and public health arrangements in the Bwindi community.,To identify the different actors involved in maternal health care provision within Bwindi community.,To identify the different policies that underpin health governance at international, national and local levels,To explore ways in which co-production of maternal health service can transform or improve multi-level health governance in developing countries,
 Uganda 2024-08-29 18:28:56 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
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