Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Julian Bagyendera Kobutungi
ID:
Gender, Youth and Social Inclusion Baseline Assessment for the USAID Local Partner Health Services – Ankole (USAID LPS – Ankole)
REFNo: SS1002ES

The main objective is to conduct a mixed method gender and youth social inclusion assessment which includes a literature review; collection of primary quantitative and qualitative data.,
 Uganda 2021-09-08 2024-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 UNDERSTANDING PATHOGENESIS OF BURKITT LYMPHOMA TO DEVELOP BETTER TREATMENTS FOR AFRICAN ENDEMIC BURKITT LYMPHOMA
REFNo: HS1546ES

4. To establish a BL tumor biorepository at the Uganda Cancer Institute ,3. To generate PDX mouse models of BL to understand the molecular factors that govern response to COM therapy in children with endemic BL at the Uganda Cancer Institute. ,2. To describe the molecular differences between endemic BL and sporadic BL. ,1. To determine the molecular profile of endemic BL tumors at the Uganda Cancer Institute,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 PERFORMANCE EVALUATION OF COVID-19 ANTIGEN RAPID DIAGNOSTIC TESTS
REFNo: HS1690ES

To determine the association of positive index test results with disease stage (days since symptom onset, e.g. acute, early, late), symptom severity and symptom severity.,To determine the diagnostic accuracy of SARS-CoV-2 Ag RDTs on a respiratory specimen (NP swab, OP swab, nasal swab, saliva), vs Cobas SARS-CoV-2 assay as performed in patients presenting with influenza-like illness.,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A clinical trial to assess the safety and immunogenicity of LNP-nCOV saRNA-02, a self-amplifying ribonucleic acid (saRNA) vaccine encoding the S glycoprotein of SARS-CoV-2, the causative agent of COVID-19, in SARS-CoV-2 seronegative and seropositive Uganda population
REFNo: HS1641ES

Primary Objective:

• To compare the safety and immune responses for SARS-CoV-2 seronegative and seropositive individuals from two immunisations with LNP-nCOV saRNA-02 administered IM 4 weeks apart at one dose level in 42 participants age 18-45 years.

Exploratory Objectives:
• To characterise the humoral and cellular immune responses to LNP-nCOV saRNA-02 administered at one dose given at 0 weeks and 4 weeks for individuals seronegative and seropositive for SARS-CoV-2 antibodies
• To characterise the profile of class and sub-class of antibody responses
• To characterize infection induced immune responses in participants with naturally acquired infection who are also exposed to the vaccine

 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
David Musoke
ID:
Collaboration between Biomedical and Traditional Mental Health Service Providers in Wakiso District, Uganda
REFNo: HS1581ES

To explore how biomedical service providers and traditional healers can work together to improve access to mental health care in Wakiso district, Uganda.
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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