Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
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Optimizing the use of SARS-Cov-2 antigen rapid diagnostic tests (Ag-RDT) for timely detection and effective response to COVID-19 in key border communities in Uganda
REFNo: HS2050ES
To evaluate the feasibility of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.
To determine the yield of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in the border districts of Tororo and Busia districts
To assess the acceptability of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.
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Uganda |
2022-04-01 |
2025-04-01 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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helen harrison
ID:
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A grounded theory epistemological exploration of wellbeing for women with lived experience of conflict-affected trauma, based in Uganda
REFNo: HS2148ES
- To use thematic-induced analysis to develop a theory relating to the epistemology of wellbeing that is grounded in the interview data,- To conduct semi-structured interviews with six – eight female participants from each of the communities.,- To explore the epistemology of wellbeing for women from three specific Uganda-based communities, each of whom has lived experience of conflict-affected trauma, and who are linked through trauma counselling,
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UK |
2022-04-01 |
2025-04-01 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Thereza Piloya Were
ID: UNCST-2019-R000491
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Diabetes in African Youth: Improving Glucose Time-In-Range (DAY Time) Randomized Clinical Trial.
REFNo: HS2129ES
Primary Study Objectives
1. To determine if patient ability to continuously observe plasma glucose levels for 6 months using a flash intermittently scanned CGM improves glucose TIR compared to baseline. The change in glucose TIR while wearing the unblinded CGM will be compared to change in TIR in patients performing 3x/day SMBG (wearing a blinded CGM for endpoint measurement).
2. To perform a cost analysis on flash glucose monitoring compared to 3x/day SMBG, to determine whether this technology is cost effective in the setting of a low-resource nation.
Secondary Objectives: To assess the change-from-baseline impact of unblinded CGM on:
1. Percent time-in-range at 12 months
2. Percent time with glucose 180-250, >250, <70, and <54 mg/dl at 6 and 12 months
3. HbA1c at 6 and 12 months
4. Patient satisfaction and quality of life at 6 and 12 months
5. Glucose variability (coefficient of variation, CV) at 6 and 12 months
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Uganda |
2022-04-01 |
2025-04-01 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Pontiano Kaleebu
ID: UNCST-2020-R019901
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Performance evaluation of the CheckNOW™ HIV Self-Test study
REFNo: HS2170ES
1. To evaluate the performance (Sensitivity and specificity) of the CheckNOW™ HIV SELF TEST when compared to the Genscreen ULTRA HIV1/2 Ag/Ab EIA followed by the Murex diasorin HIV1/2 Ag/Ab combination (reference testing) in the laboratory and the national testing algorithm.
2. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the professional users, when compared to the reference testing and the national testing algorithm.
3. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the lay users, when compared to the reference testing and the national testing algorithm.
4. To assess the accuracy of the lay user interpretation of the HIVST result. This will be compared with the interpretation by the RA.
5. To assess the usability of the CheckNOW™ HIV SELF TEST. The usability of the test will be evaluated by questionnaires completed by the study staff observers and by the lay users.
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Uganda |
2022-04-01 |
2025-04-01 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Samson Okello
ID: UNCST-2019-R001580
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Epidemiology of cardiac dysfunction in sub-Saharan Africa: Heart Failure Registry of HIV-infected and HIV-uninfected persons in Uganda and Zambia
REFNo: HS788ES
1. To describe the clinical characteristics, treatment outcomes, and predictors of all-cause and CV mortality among HIV-infected and HIV-uninfected heart failure adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
2. To describe echocardiographic etiology of heart failure among HIV-infected and uninfected adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
3. To determine the differences in the serum markers of cardiac fibrosis, cardiac injury, oxidative stress, and hypercoagulability in HIV-infected and HIV-uninfected individuals hospitalized with heart failure at Mbarara Regional Referral Hospital and the University of Zambia Hospital.
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Uganda |
2022-03-30 |
2025-03-30 |
Medical and Health Sciences |
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Non-degree Award |
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