Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ruth Namazzi
ID: UNCST-2020-R014305
Alternative Dosing And Prevention of Transfusions (ADAPT): A prospective study to reduce transfusion requirements for children with sickle cell anemia using pharmacokinetics-based hydroxyurea dosing
REFNo: HS2093ES

Primary Objective • To compare the rates of blood transfusions overall and by specific indications in children with sickle cell anaemia (SCA), prior to and during hydroxyurea treatment Secondary Objectives • To determine clinical and laboratory factors associated with reduction in blood transfusions for children with SCA on hydroxyurea treatment
• To assess the feasibility and safety of a pharmacokinetic (PK)-based hydroxyurea dose within the predicted treatment range for Uganda
• To quantify rates of SCA-related complications (including stroke, sepsis, and pain) in participants receiving PK-guided hydroxyurea dosing and within the overall cohort on hydroxyurea treatment

Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Bulafu
ID: UNCST-2021-R011774
Adherence to Malaria Treatment Guidelines among Health Care Workers in Private Health Facilities in Kampala’s informal Settlements, Uganda
REFNo: HS2161ES

To explore barriers and facilitators towards malarial treatment guidelines among HCWs in private health facilities,To assess the factors associated with adherence to malaria treatment guidelines among HCWs in private health facilities,To establish the level of adherence to malaria treatment guidelines among HCWs in private health facilities,To assess adherence to malaria treatment guidelines and associated factors among HCWs in private health facilities in Kampala's informal settlements, Uganda,
Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rachel Nankanja Babirye
ID:
FIGO/AOGU Advocacy for the Prevention of Maternal Mortality and Morbidity in Uganda (APMM) due to unsafe abortion –end evaluation of a three years’ multi-country capacity building project
REFNo: SS1249ES

1. To document the results and achievements achieved by FIGO and the member societies
2. To analyse the contribution of the project in strengthening the societies and the results achieved
3. To assess the project implementation by FIGO and the member societies, including lessons learned.
4. To extract lessons learned – “understanding enabling and hindering factors in advocacy for CAC, including safe abortion within the context of the law”

Uganda 2022-04-13 2025-04-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
Enhancing prediction of adverse pregnancy outcomes in Africa through partnerships and innovation
REFNo: HS2195ES

4. Calibrate the intersection between socio-epidemiological, clinical and laboratory parameters of the GOS using artificial intelligence.,3. To generate a resource of data and biological samples to facilitate hypothesis driven and discovery based approaches to identifying novel predictors and/or mechanisms of pre-eclampsia and the other GOS. ,2. To determine the positive predictive value of screening using biomarkers (soluble Flt-1 and placental growth factor) and serial ultrasound for the different adverse pregnancy outcomes in (1) above.,1. To determine the exposures (epidemiological, social, demographic, clinical, laboratory) linked to the different outcomes - pre-eclampsia, stillbirth, preterm birth and fetal growth restriction.,To enhance prediction of adverse pregnancy outcomes in Africa through partnerships and innovation,
Uganda 2022-04-13 2025-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jörg Wiegratz
ID:
Changing the game: The dynamics of the commercialisation of football in Eastern Africa
REFNo: SS1246ES

This project is a comparative study of the ongoing and intensifying dynamics of commercialisation of football in East Africa. The aim is to empirically investigate and map the major drivers, characteristics and repercussions (also in terms of development of football, i.e. professionalism, performance, club management, fan experience, popularity etc.) of the commercialisation in two countries: Kenya and Uganda. It aims to capture stakeholders’ experiences, insights and views concerning commercialisation of football. The overall question is: what changes are triggered by the commercialisation of local football? I will talk to various stakeholders and gain some insights into developments at different clubs and commercial developments in Kampala/the country. These case studies will allow me to explore the dynamics of introducing cutting-edge commercial models in sports leagues on a continent that has had – compared to other regions – relatively low levels of commercialisation until recently. This will enable a better understanding of commercialisation-in-practice – and respective similarities and differences across the two sites - in a key football region in the Global South. The findings will inform relevant public/policy debates in the two countries, the region generally and beyond (e.g. at global level) regarding various aspects of the commercialisation of soccer. The study will contribute to the relatively nascent literature on commercialization in Africa generally. It will also draw lessons regarding commercialisation processes and issues that might be applicable to other countries in Africa and beyond.
Germany 2022-04-12 2025-04-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
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