Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nixon Niyonzima
ID: UNCST-2020-R014577
Utility of a Liquid Blood Biopsy for Non-invasive Lung Cancer Diagnosis and Biomarker Testing at Uganda Cancer Institute.
REFNo: HS1743ES

1. To compare ctDNA sequencing to standard histopathologic diagnoses of lung cancer in patients with advanced stage lung cancer at the Uganda Cancer Institute (UCI).

2. To describe the tumor-specific molecular alterations present in lung cancer specimens and ctDNA in advanced stage lung cancer patients at UCI.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
Childhood victimization and mental disorders among adolescents of sex-working and non-sex working mothers in post-conflict Gulu city in Northern Uganda - a cross-sectional study
REFNo: HS1769ES

The main goal of this study is to provide the evidence needed by the health care programmers and policymakers to inform appropriate policies and practices on prevention, screening, and management of victimizations among adolescents in Uganda. Specifically, the following are the study objectives:
1. To determine the prevalence of childhood victimization among adolescents.
2. To examine the relationship between sociodemographic characteristics and general health and childhood victimization among adolescents.
3. To examine the relationship between maternal sex work status and childhood victimization.
4. To examine the relationship between maternal major depression and childhood victimization among adolescents.
5. To determine the prevalence of selected childhood mental disorders among adolescents.
6. To examine the relationship between exposure to childhood victimization and childhood mental disorders in post-conflict Gulu City.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Interrupting HIV and TB Stigma in the Household during TB Contact Investigation in Uganda
REFNo: HS1788ES

This project aims to evaluate the effects of a complex intervention on household HIV stigma and uptake of HIV testing among household members undergoing TB contact investigation.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
Evaluating the impact of the COVID-19 pandemic restrictions on HIV care in Kampala, Uganda: a propensity-score matched and difference-in-differences analysis
REFNo: HS1709ES

Primary objective: To evaluate the impact of the COVID-19 pandemic restrictions on linkage to care, time to linkage, timely ART initiation, retention in care, viral load suppression, and mortality among people living with Human Immunodeficiency Virus (PLHIV) in the Kampala Capital City Authority (KCCA) health facilities in central Uganda

Secondary objective: To document and synthesize measures for continuity of service delivery for PLHIV during the COVID-19 pandemic
Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty  Nambuusi Bukenya
ID:
Youth Wellbeing Champions: Piloting community-based, youth peer-led mental health and wellbeing support for young people in Uganda
REFNo: SS956ES

Study goal: To generate evidence around the effectiveness of a pilot community-based and responsive wellbeing / mental health intervention led by young people with lived experience of care and supported by social work practice/practitioners in Uganda. Specific objectives 1. Assess the level of knowledge and understanding of a trauma-informed approach to addressing mental health needs among social workers based on the Kirk Patrick pre-post questionnaire. 2. Assess the prevalence of clinical mental health, well-being, self-esteem/ self-worth, and depression symptoms among children and youth based on the WHO-5 / PHQ-9 and Rotter’s Locus of Control. 3. Examine the level of knowledge of mental health literacy, resilience, psychosocial support, and wellbeing practice among care leavers based on Kirk Patrick's pre-and post-assessments questionnaire.
Uganda 2021-10-12 2024-10-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
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