Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ERIC WOBUDEYA
ID: UNCST-2019-R001047
A randomised trial of 6 months intensified anti-tuberculosis and 2 months anti-inflammatory treatment for HIV-infected and HIV-uninfected African and Asian children with tuberculous meningitis
REFNo: HS593ES

Main objectives of the SURE trial

a) To determine whether the standard 12 month ATT regimen for treating paediatric TBM can be reduced to 6 months with similar efficacy and safety, with an intensified regimen of anti-TB drugs in children aged under 15 years with TBM AND b) To determine whether adjunctive aspirin for the first 60 days of treatment reduces TBM-related neuro-disability with minimal or no toxicity in children with TBM.

Other objectives

(a) To determine whether the doses of anti-TB drugs, prescribed according to weight bands, result in appropriate drug exposures when compared with historical paediatric and adult PK data.

(b) To further understand the pathophysiology of TBM in children and the effects of intensified antibacterial and anti-inflammatory treatment on intra-cerebral inflammation and the macroscopic complications of TBM (infarcts, tuberculomas, hydrocephalus).
Uganda 2020-04-30 2023-04-30 Medical and Health Sciences Non-degree Award
Annette Schuh Hildegard
ID: UNCST-2024-R003745
Evaluation and Transfer of mobile whole slide tissue scanners and liquid biopsies to deliver fast and precise diagnosis for improved outcomes of children and young adults with EBV-driven lymphoma: a joint Tanzanian and Ugandan Paediatric Oncology Network Initiative
REFNo: HS529ES

We have four objectives: to 1. Assess the diagnostic accuracy of liquid biopsy testing 2. Asses the diagnostic accuracy of digital pathology 3. Development of a digital pathology machine learning algorithm 4. Transfer of above novel tests and associated expertise to local laboratories
UK 2020-04-24 2023-04-24 Medical and Health Sciences Non-degree Award
Peter Nkurunziza Munya
ID:
'Evaluation of The Bio-Rad Geenius HIV-1/2 Confirmatory Assay as Part of Confirmatory and Differentiation of HIV infection at Uganda Virus Research Institute-HIV Reference Laboratory'
REFNo: HS612ES

Primary objective
• To conduct an in-country evaluation of the performance of Geenius™ HIV-1/2 Confirmatory Assay for confirmation of HIV infection using DBS and Plasma specimens, as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.
Specific objectives
• To determine the sensitivity of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the specificity of the Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the positive predictive value and negative predictive value of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.

Uganda 2020-04-24 2023-04-24 Medical and Health Sciences Non-degree Award
PROSPER BEHUMBIIZE
ID:
Implementation Research on Education Management Information Systems (EMIS) Data Use Innovations in Uganda
REFNo: SIR33ES

1. To assess the existing management information systems for the Education Sector
2. To understand how innovations including DHIS2 can be used to improve EMIS data quality, management and use at all levels of the education sector
3. To ascertain the best practices that will inform scale up of Dhis2-for Education within and across countries

Uganda 2020-04-17 2023-04-17 Engineering and Technology Non-degree Award
Peter Olupot-Olupot
ID:
Coronavirus Disease 2019 Open Cohort (COC) Study
REFNo: HS611ES

The specific objectives:
1. Through a cross sectional survey describe risk factors and enlist study participants for the cohort study.
2. To characterize the clinical spectrum of COVID-19.
3. To refine case definitions of COVID-19 using data from different population groups.
4. To explore in detail, the epidemiology of COVID-19.
5. To document outcomes associated with COVID-19 in various age groups, populations and concomitant conditions.
6. To generate data to inform clinical research on COVID-19.
7. To generate population specific data for evidence based public health education as a control measure.
8. Provide a decision tree that has automated feedback that has standard of care including quarantine, call help-line, seek medical attention and avoid spread of the disease.

Uganda 2020-04-03 2023-04-03 Medical and Health Sciences Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
Acceptability, effect and cost of mobile-health on art adherence among youths: a mixed methods sequential study in Kiryandongo
REFNo: HS576ES

General objective: To assess the acceptability, effect and cost of the Call For Life Uganda mHealth tool on ART adherence among youth initiating ART at Kiryandongo Hospital.

Specific objectives:
Objective 1a: To assess barriers, enablers of ART adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 1b: To assess acceptability of mHealth for HIV adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 2: To assess effect of the CFLU mHealth tool on ART adherence among youths initiating ART at 6 and 12 months.
Objective 3: To evaluate the cost of the CFLU mHealth adherence tool in comparison to Standard of Care.

Uganda 2020-03-28 2023-03-28 Medical and Health Sciences Degree Award
Anthony Matovu
ID:
G - Therapy: Classical Mechanical Resonance Tool For HIV Cure
REFNo: SIR26ES

Main Objective
To design and implement an effective, safe, “isolate – and – kill” Classical Mechanical resonance tool for HIV – riddance from HIV – positive patients.

Specific Objectives
a) To outline a velocity, frequency and wavelength generating system based on scalable vibratory/circulatory dynamics pertinent with the vibratory characteristics of the HIV particles (H – 1 atom system is earmarked).
b) To identify the HIV virus by morphology (physical structure) differentiation using light optical nanoscopy – observation procedures (use flue virus for comparison).
c) To characterize the projected mechanical resonance – based fight between HIV and human defense system cells (realizable by articulating and relating factors implicated).
d) To design and implement a counter resonance tool against HIV’s own mechanical resonance combat weapon against human defense cells (achievable through determining rupture-prone resonant frequency-amplitude factors leading to an effective, safe body- penetrative capacity; as well as the functional body/specimen exposure period).

Uganda 2020-03-20 2023-03-20 Engineering and Technology Degree Award
Doreen Nakku
ID:
Assessment of knowledge and attitudes towards hearing loss and community utilisation of hearing screening services at a Health Centre IV in Mbarara District
REFNo: HS549ES

1. To assess knowledge on hearing loss and attitudes towards hearing loss of communities served by Bwizibwera HC IVs in Mbarara District
2. To assess the utilisation of hearing screening services at Bwizibwera HC IVs in Mbarara District.
Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Non-degree Award
KAHUNZIRE EVANGELIST
ID:
Evaluation of parental involvement on primary pupils educational academic performance in public day primary schools of Ndorwa County,Kabale District-Uganda.
REFNo: SS426ES

To establish the relationship between parental involvement on primary pupils educational academic performance in selected public day primary schools of Ndorwa County,Kabale District-Uganda.
To examine the utilization of educational domains on primary pupils'educational academic performance in selected public day primary schools of Ndorwa County ,Kabale District-Uganda.
To formulate a parenting involvement model that enhances primary pupils'educational academic performance in selected public day primary schools of Ndorwa Ounty,Kabale District-Uganda.
Uganda 2020-03-20 2023-03-20 Social Science and Humanities Degree Award
Paddy Tukamuhebwa Mutungi
ID: UNCST-2020-R014201
Barriers and facilitators of investigation coverage among index tuberculosis case contacts in rural Mbarara district, Uganda.
REFNo: HS569ES

1. To identify the barriers of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district in Uganda. 2. To identify the facilitators of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district, Uganda.
Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Degree Award
Charles Batte
ID: UNCST-2021-R013587
Hypertension and cardiovascular diseases comorbidities among people living with HIV: A health outcomes and cost study.
REFNo: HS581ES

• To determine and compare Health Related Quality of Life (HRQoL) of People living with HIV (PLWH) with or without hypertension and/or CVD comorbidities that have been on ART for more than 10 years in Uganda using both generic and disease specific HRQoL tools.
• To determine and compare health care utilization costs of patients with HIV & HTN/CVD and those with HIV alone.

Uganda 2020-03-20 2023-03-20 Medical and Health Sciences Non-degree Award
Peter MUSINGUZI
ID:
Social Enterprises and sustainable rural development: performance and impacts on beneficiaries’ livelihood
REFNo: SS434ES

General objective To guide the design and operation of Social Enterprises in rural development Specific objectives 1.To analyse what CSFs determine the performance of SEs 2.To understand how the presence and influence of CSFs in SEs varies across contexts. 3.To determine and describe how SE management and performance influence impact on stakeholders.
Uganda 2020-03-20 2023-03-20 Social Science and Humanities Degree Award
Obbo Aggrey
ID:
Algorithms for detection and management people crowds using wireless sensor networks
REFNo: SIR31ES

Design develop and analyze algorithms for people crowds detection and management using wireless sensor networks.
Uganda 2020-03-20 2023-03-20 Engineering and Technology Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Influencing Sepsis policy in Uganda
REFNo: HS517ES

The main objective of this study is to generate evidence on how researchers’ stakeholder engagement influences Uganda’s health policy agenda. The study will be guided by the following specific objectives.
1. Assess changes in Uganda’s health policy agenda around sepsis as a result of ARCS policy stakeholder engagement activities.
2. Reflectively review the process stakeholder engagement strategies (Informing and translating, Linking, Matchmaking, and Capacity strengthening) designed to influence key stakeholders to recognise sepsis as a priority health issue and put it on Uganda’s policy agenda.

Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Non-degree Award
Catherine Carlson
ID: UNCST-2023-R007222
Promoting Resilience for Survivors of Trafficking: Evaluating a Yoga-Based Approach in Kampala, Uganda
REFNo: SS420ES

Healing and Resilience through Yoga (Hart Yoga) is a trauma-informed yoga program to support survivors of human trafficking in Uganda with psycho-social recovery. The
proposed study will evaluate Hart Yoga’s feasibility, acceptability and impact with women and adolescent girls residing in Willow International’s (https://www.willowinternational.org/) shelters for survivors of human trafficking in Kampala, Uganda. This study will advance the limited field of health and mental health research with survivors of human trafficking and provide pilot data for publication and the development of a subsequent effectiveness trial. The methodology will address two primary objectives:

• Objective 1: To determine Hart Yoga’s feasibility and acceptability among participants and successful delivery within a residential shelter setting.
• Objective 2: To assess physical, psychological and social outcomes among program participants using qualitative and quantitative methods.

USA 2020-03-18 2023-03-18 Social Science and Humanities Non-degree Award
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
Project Evaluation Protocol for West-West Nile Region mechanism.
REFNo: HS554ES

Evaluation Objective 1: To evaluate the targeted HTS models to improve earlier identification of HIV positive and negative individuals, and Linkage of PLHIV in community and facility sites in scale up districts and linkage and promotion of HIV prevention among HIV negative individuals.

Evaluation Objective 2: To evaluate innovative approaches that increase adherence, ART retention and viral load suppression among adult and pediatric HIV clients.

Evaluation objective 3: To determine if there is improved identification of TB infected individuals., effective scale up of comprehensive TB/HIV services at individual sites site, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC supported regions and districts.

Evaluation objective 4. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV positive and syphilis infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, viral load suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV & Syphilis and ensure documentation of 18 month final outcome status for all HIV Exposed infants.

Evaluation objective 5: To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at facility and district level.

Evaluation objective 6 : To determine if there was increase access of comprehensive OVC services .

Evaluation objective 7: To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at facility and district level.

Evaluation Objective 8: To determine if the relationship between district level performance reviews and HR performance had an effect on district performance including access, coverage, retention and loss to follow up.
Evaluation objective 9: To determine if Kampala region mechanism approaches resulted in increased coverage with voluntary medical male circumcision.



Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Non-degree Award
Noah Sendawula
ID:
Youth Livelihood Programme & Empowerment in Wakiso District
REFNo: SS430ES

Main Objective: To assess the effectiveness of Youth Livelihood Programme on Youth Empowerment in Wakiso District.
Specific:
i-To investigate the extent to which YLP has been able to provide vocational skills for youth self-employment in Wakiso District
ii- To analyse the extent to which YLP financial support has enabled youth establish income generation activities in Wakiso district
iii- To examine the extent to which YLP has been able to increase levels of entrepreneurship among youth in Wakiso District.
iv- To extablish the extent to which knowledge & information has been provided for positive mindset change among youth in Wakiso district
Uganda 2020-03-18 2023-03-18 Social Science and Humanities Degree Award
Peter Byansi Kayiira
ID:
Leadership and Management Practices that Support Accountability for Results in Health Support Organizations in Uganda
REFNo: HS585ES

Inquire into the management and leadership practices that health leaders in Uganda’s public and nonprofit health support organizations use and have found effective in nurturing accountability for the achievement of results that matter most to employees, the organization, customers, and donors, hereinafter referred to as key stakeholders
Uganda 2020-03-18 2023-03-18 Medical and Health Sciences Degree Award
Robert Kairania
ID:
Performance of the Asanteâ„¢ HIV-1 Rapid Recencyâ„¢ Assay in recent HIV infections detection and incidence estimation in a Ugandan setting using the Rakai Community Cohort Study
REFNo: HS534ES

Main aim: To determine the performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of HIV-1 recent infections and incidence estimation in a Ugandan setting with A and D predominant subtypes.

Specific aims
I. To evaluate the diagnostic performance of the Asanté™ HIV-1 Rapid Recency™ assay in identification of recent infections in a setting with A and D predominant subtypes.
II. To establish the false recency rate (FRR) of the Asanté™ HIV-1 Rapid Recency™ assay.
III. To determine factors associated with being misclassified as recent by the Asanté™ HIV-1 Rapid Recency™ assay.
IV. To compare HIV incidence estimated using the Asanté™ HIV-1 Rapid Recency™ assay from a cross-sectional survey with that observed longitudinally in an observational cohort in Rakai.

Uganda 2020-03-16 2023-03-16 Medical and Health Sciences Non-degree Award
Gerry McGivern
ID:
Strengthening health professional regulation in Kenya and Uganda
REFNo: SS336ES

The research aims to develop evidence about how health professional regulation is enacted and experienced by doctors and nurses in Ugandan and Kenyan and ways it might be improved.
UK 2020-03-12 2023-03-12 Social Science and Humanities Non-degree Award
Aala Abdelgadir
ID:
Mosque Mapping Survey
REFNo: SS385ES

Religious institutions play an important role in the daily lives of Ugandans, as in other African countries. Yet, we understand little about the influence of religious institutions on social and political outcomes. This project focuses on the sway of Muslim religious institutions in shaping the opinions and behaviors of congregants. Specifically, we will study how mosques communicate with congregants, what types of messages they deliver, and how messages shape the attitudes and behaviors of congregants.

The research objectives of this project are to:
• Examine variation in sermons, including topics, religious citations, and tone.
• Assess how mosque and imam characteristics influence the nature of sermons.
• Explore how sermons shape congregant religious, social, and political attitudes and behaviors.

USA 2020-03-12 2023-03-12 Social Science and Humanities Degree Award
Scholastic Ashaba
ID: UNCST-2023-R007613
Transition readiness among adolescents living with HIV in Uganda
REFNo: HS512ES

Aim 1: Use qualitative research to elaborate a conceptual model of transition readiness for perinatally-infected ALHIV in Mbarara, Uganda (n=up to 50 in-depth interviews).
Aim 2:Develop and validate a transition readiness scale for perinatally-infected ALHIV (n=340)
Uganda 2020-03-12 2023-03-12 Medical and Health Sciences Non-degree Award
Catherine Abbo
ID:
The Ugandan Early Childhood Phenoscreening Project
REFNo: HS544ES

1. To evaluate the psychometric properties of selected parent-report questionnaires among a community sample of infants and toddlers in Uganda.
2. To identify homogenous subgroups or behavioural risk profiles in a community sample of infants and toddlers
3. To determine the average age of autism spectrum disorder diagnosis in children attending mental health clinics in Mulago and Butabika hospitals
Uganda 2020-03-12 2023-03-12 Medical and Health Sciences Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Alcohol use, Intimate Partner Violence (IPV) & HIV Risk among Young People in fishing communities on the shores of Lake Victoria, Uganda
REFNo: SS421ES

Aim of the study
The aim of the study is to determine the factors associated with HIV risk among young people in fishing communities on the shores of Lake Victoria, in eastern Uganda.
Objectives of the study
1. To estimate the association between alcohol use and HIV risk among young people in in the fishing communities on the shores of Lake Victoria, Uganda
2. To determine the association between intimate partner violence (IPV) victimization (females) and perpetration (males) and HIV risk among young people in the fishing communities on the shores of Lake Victoria, Uganda

Uganda 2020-03-12 2023-03-12 Social Science and Humanities Non-degree Award
Alex  Muganzi Muganga
ID: UNCST-2019-R000710
Project Evaluation Protocols for Kampala Region mechanism
REFNo: HS553ES

Evaluation Objective 1: To evaluate the targeted HTS models to improve earlier identification of HIV positive and negative individuals, and Linkage of PLHIV in community and facility sites in scale up districts and linkage and promotion of HIV prevention among HIV negative individuals.

Evaluation Objective 2: To evaluate innovative approaches that increase adherence, ART retention and viral load suppression among adult and pediatric HIV clients.

Evaluation objective 3: To determine if there is improved identification of TB infected individuals., effective scale up of comprehensive TB/HIV services at individual sites site, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC supported regions and districts.

Evaluation objective 4. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV positive and syphilis infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, viral load suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV & Syphilis and ensure documentation of 18 month final outcome status for all HIV Exposed infants.

Evaluation objective 5: To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at facility and district level.

Evaluation objective 6 : To determine if there was increase access of comprehensive OVC services.

Evaluation objective 7: To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at facility and district level.

Evaluation Objective 8: To determine if the relationship between district level performance reviews and HR performance had an effect on district performance including access, coverage, retention and loss to follow up.

Evaluation objective 9: To determine if Kampala region mechanism approaches resulted in increased coverage with voluntary medical male circumcision.


Uganda 2020-03-12 2023-03-12 Medical and Health Sciences Non-degree Award
Anthony Makhoba
ID:
MODELING A BCG BIRTH DOSE VACCINATION PROGRAM FOR IMPROVED HEPATITIS B CONTROL IN UGANDA
REFNo: HS415ES

1. To determine the rate of BCG birth dose vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital.
2. To determine the time to BCG vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital
3. To establish reasons for missed/delayed BCG vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital and to propose means of improvement.
4. To document the human costs of birth dose vaccination i.e. the nurse time required to obtain maternal consent, to draw up and administer the vaccine and complete the immunization record.

Uganda 2020-03-11 2023-03-11 Medical and Health Sciences Non-degree Award
Sudi Mohamed Ali
ID:
Cervical Cancer: Late presentation and associated factors at Mbarara Regional Referral Hospital.
REFNo: HS485ES

1. To determine the proportion of women with cervical cancer that presents late at Mbarara Regional Referral Hospital. 2. To determine the factors associated with late presentation among women with cervical cancer at Mbarara Regional Referral Hospital. 3. To explore the factors associated with health care seeking from onset of symptoms to diagnosis among women with cervical cancer at Mbarara Regional Referral Hospital.
Kenya 2020-03-11 2023-03-11 Medical and Health Sciences Degree Award
Richard  Muhumuza
ID:
INTEGRATED PREVALENCE MAPPING OF SCHISTOSOMIASIS AND SOIL TRANSMITTED HELMINTHIASIS AMONG COMMUNITIES IN MAYUGE DISTRICT: IMPLICATIONS FOR NTD ELIMINATION PROJECT 2019-2021
REFNo: HS434ES

2. Study objectives
2.1 General objective/Goal
The establish the prevalence of Schistosomiasis and STH infections among school going children and surrounding communities in Mayuge district

Specific objectives
1. To build capacity of Laboratory assistants and technicians on sample (Stool) collection and microscopic analysis
2.To collect sample (Stool) collect from the selected schools
3. To conduct Microscopic analysis for collected samples


Uganda 2020-03-09 2023-03-09 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
Assessment of Public Knowledge, Attitudes, and Practices Related to Ebola Virus Disease Prevention and Treatment in Uganda
REFNo: HS531ES

1. Measure district-level estimates in six districts in Uganda of the public’s knowledge, beliefs, attitudes, and practices related to Ebola Virus Disease (EVD) risks due to the ongoing and widespread EVD outbreak in DRC; and
2. Identify socio-behavioral and health system barriers that may hinder the containment of an EVD outbreak in Uganda given the complex socio-political and security context of the protracted outbreak in neighboring DRC.

Nigeria 2020-03-09 2023-03-09 Medical and Health Sciences Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Improving neonatal outcomes through early detection and management of hypoxaemia: The role of routine pulse oximetry
REFNo: HS132ES

1.To evaluate the effect of routine pulse oximetry on neonatal outcomes in the first 24 hours of life. 2.To determine the utility of pulse oximetry compared to clinical signs in detection of hypoxaemia in neonates with possible serious bacterial infections at lower level facilities 3.To assess the feasibility and acceptability of routine pulse oximetry by healthcare workers and caretakers of newborn babies. 4.To determine the cost-effectiveness of routine pulse oximetry in identifying neonates with hypoxaemia. 5.To describe the maternal factors that predict hypoxaemia in the newborn babies
Uganda 2020-03-06 2023-03-06 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Advancing Tissue and Organ Biobanking in Uganda
REFNo: HS572ES

General objective: To establish a tissue and organ biobank at Makerere University to serve as a catalyst for research in organ collection, biobanking and transplantation in Uganda.
Specific Objective :
1. To train personnel and develop standard operating procedures for collection, processing and storage of human ova, sperm and umbilical cord blood.
2. To collect, process and store human ova, sperms and umbilical cord blood.
3. To develop a publicly accessible catalog of HLA typed viable human tissue and organs.
4. To explore the ethical, legal and societal issues (ELSI) in human tissue and organ biobanking

Uganda 2020-03-03 2023-03-03 Medical and Health Sciences Non-degree Award
ROSE ATIM
ID:
Law, Culture and Reality: Women Navigating Post Conflict Marital Relations in Northern Uganda
REFNo: SS423ES

1. Investigate the legal implication of the institution of marriage on women born in internally displaced peoples camps and victims of sexual violence of the LRA conflict;
2. Interrogate if cohabitation as an alternative to ‘legal’ marriage is becoming institutionalized among women born in internally displaced peoples camps and victims of sexual violence of the LRA Conflict;
3. Analyse the effectiveness of legal and informal marital protection mechanisms in a post conflict society;
4. Interrogate the future of the law in customary marital unions.

Uganda 2020-03-03 2023-03-03 Social Science and Humanities Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
SAFETY AND EFFICAY OF DOLUTEGRAVIR AND EFV 400 FOR PREGNANT AND BREAST FEEDING WOMEN; A RANDOMISED NON INFERIORITY CLINICAL TRIAL ACRONYM: PREGART
REFNo: HS515ES

PRIMARY OBJECTIVE; to identify safer and more effective ART regimen for pregnant and breast feeding women by comparing three alternative first line ART regimens for their safety and efficacy using randomized clinical trial.

SECONDARY OBJECTIVE; To provide evidence based recommendations for safe and effective first line ART regimens for prevention of mothers to child transmission and treatment of HIV infected pregnant and breast feeding women living in resource limited setting.

Uganda 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
Outcomes Following Surgical Release of Gluteal Fibrosis in Children of Eastern Uganda
REFNo: HS561ES

This study is a longitudinal case series to evaluate if surgical release of gluteal fibrosis in Ugandan children has a sustained benefit. We will examine the two-year outcomes after surgical release of gluteal fibrosis in children undergoing surgical intervention for gluteal fibrosis.

USA 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
NAASSON TUYIRINGIRE
ID:
Metabolomics Approaches to Elucidate the Mechanisms of Action of Antimycobacterial Medicinal Plants
REFNo: HS422ES

The main objective is to elucidate the mechanisms of action of antimycobacterial medicinal plants using metabolomics. The specific objectives are:
1. To determine the metabolome of M.tb subjected to medicinal plant extracts with antimycobacterial activity as compared to control culture
2. To optimize an analytical metabolomics workflow to facilitate reproducible measurements of bacterial metabolome with extract treatment or without the treatment
3. To elucidate the metabolic pathways affected by plant extracts
4. To identify the macromolecule targets of plant extracts

Rwanda 2020-02-21 2023-02-21 Medical and Health Sciences Degree Award
Jean Damascene Niyonsenga
ID:
Exercise and well-being: NCD risks and constraints to Physical Activity and sports participation among Ugandan rural and urban secondary school students
REFNo: HS490ES

1. To examine the correlation between NCDs risk factors and level of physical activity/sports participation, type of eaten food, and lung function among both rural and urban secondary school students in Mbarara, uganda
2. To establish constraints to PA/sports participation of secondary school students in rural and urban schools in Mbarara, Uganda.
3. To examine the relationship between internal motivation and external support for PA/sports participation for secondary school students in rural and urban schools of Mbarara, Uganda.
4. To determine the commonest sustained injuries and to establish the proportion attributable to PA/sports among rural and urban secondary school students in Mbarara, Uganda.
5. To compare constraints and injuries identified by secondary school students from rural and urban schools in Mbarara, Uganda.

Rwanda 2020-02-21 2023-02-21 Medical and Health Sciences Non-degree Award
Robert Kairania
ID:
Exploration of psychological distress and cross-cultural adaptation of a mental health measure for people living with HIV in Rakai, Uganda
REFNo: SS408ES

Aim 1: To characterize local manifestations of psychological distress among people living with HIV in rural communities in Rakai, Uganda

Aim 2: To identify and cross-culturally adapt appropriate mental health measurement instruments based on findings from Aim 1.

Aim 3: To validate the adapted mental health measurement instrument within the rural Rakai population.

Uganda 2020-02-21 2023-02-21 Social Science and Humanities Non-degree Award
Vincentina Achora
ID:
Postpartum haemorrhage in Northern Uganda: Community perspectives; burden and associated factors; Health Facilities preparedness for its management; and outcomes
REFNo: HS518ES

1. To explore the community perspectives of PPH in Lira district.
2. To assess the level of health facilities preparedness for management of labour, delivery and postnatal care in prevention of PPH in Lira district.
3. To describe the burden and factors associated with PPH among mothers delivering in Lira district and Lacor Referral hospital.
4. To describe the factors associated with outcomes of PPH among mothers delivering in Lira district and Lacor Referral hospital.

Uganda 2020-02-21 2023-02-21 Medical and Health Sciences Degree Award
Maria Nakku Elizabeth Mirembe
ID:
Women in Higher Education: An Ethnographic Case Study of Women Lecturers and Administrator Experience in Selected Universities in Uganda
REFNo: SS410ES

1. To investigate how women lecturers and administrators advance the institutional mission of teaching, scholarship, and service in selected universities in Uganda
2. To explore how the culture of higher education shape and affect women leadership
3. To examine the obstacles and challenges do women experience as lecturers and administrators in higher education
4. To assess common attributes and strategies support women’s success in higher education teaching and administration in Uganda


Uganda 2020-02-21 2023-02-21 Social Science and Humanities Degree Award
Lawrence Mugisha
ID:
Developing Monitoring System for Quantifying and Mapping Antimicrobials used in Livestock Farming Systems in Uganda
REFNo: HS538ES

1. To determine the proportions of different types of antimicrobials imported into Uganda for use in livestock production systems.
2. To determine the volumes of antimicrobial medicines imported into Uganda for use in livestock production systems.
3. To map and create an inventory of manufacturers, importers, distributors and medicine stockists of antimicrobials used in livestock production systems in Kampala, Wakiso and Mukono districts.
4. To develop an information technology (IT) monitoring system for monitoring importation, distribution and consumption of antimicrobials used in livestock production systems

Uganda 2020-02-21 2023-02-21 Medical and Health Sciences Non-degree Award
Herbert Muyinda
ID: UNCST-2019-R000373
Cango Lyec (Healing the Elephant) Study: Determining HIV Vulnerabilities and Designing Targeted Interventions to Improve Clinical outcomes among conflict affected Adolescent girls and young women under 25 in Northern Uganda
REFNo: HS521ES

1. Estimate prevalence and incidence of HIV, Hepatitis B, and syphilis, and identify associated risk factors among conflict-affected young women in Northern Uganda

2. Investigate associations between posttraumatic stress, resilience, and depression with HIV incidence among conflict-affected young women in Northern Uganda

3. Pilot feasibility and acceptability of comprehensive mHealth package to support engagement in HIV care among conflict-affected young women living with HIV in Northern Uganda

Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Dathan  Byonanebye Mirembe
ID:
Impact of Mobile Health Interactive Software on Tuberculosis Treatment Outcomes: The Call for Life (CFLU-TB) Project
REFNo: HS524ES

To determine the effect of CFLU-TB on TB treatment success (treatment completion and cure rates) in patients with TB receiving care at three public health facilities in Uganda.
1. To compare TB cure rates (six months) in patients with microbiologically diagnosed TB in the intervention and control arms.
2. To compare treatment completion (six months) in patients clinically diagnosed with TB in the intervention and control arms.
3. To determine the effect of enhanced TB treatment support with CFLU-TB on retention at 2 and 6 months in patients receiving TB treatment at Kisenyi Health Center IV.
4. To assess perception of patients’ care providers (treatment buddies) and other stakeholders towards the CFLU-TB.
5. To determine the cost-effectiveness of the CFLU-TB intervention.
6. To compare adherence rates between patients in the intervention arm and control arms.
7. To determine the effect of CFLU-TB on adherence to clinic appointments.
8. To compare knowledge about TB/HIV in patients enrolled in the intervention and control arms.
9. To determine Drug-resistant TB rates in the intervention and control arms.
10. To determine the uptake of the CFLU-TB tool in patients and their care providers (treatment buddies).


Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Fredrick Mutungi
ID:
CONTEXT-FITTING MOBILE SERVICES FOR MONITORING THE DELIVERY OF PUBLIC HEALTH SERVICES
REFNo: SIR20ES

1. To identify the performance indicators of mobile services for monitoring the delivery of public health services.
2. To establish the performance of existing mobile services used for monitoring the delivery of public health services.
3. To find out the contextual factors affecting the performance of mobile services for monitoring the delivery of public health services.
4. To design a model for guiding development of context-fitting mobile services for monitoring delivery of public health services.
5. To establish performance improvements anticipated with the use of context-fitting mobile services when monitoring the delivery of public health services.

Uganda 2020-02-19 2023-02-19 Engineering and Technology Degree Award
John Mark Bwanika
ID:
Utilization Of Telehealth (Tele-care) To Improve Post-Clinic Therapy For Youths with HIV and Depression- A Feasibility Study.
REFNo: HS539ES

-Design and develop mobile/web content for post-clinic telecare for young adult HIV patients with depression.

-Assess feasibility and acceptability of the telehealth intervention Package (Telecare) for depression among HIV young adult patients as well as their post-intervention self-efficacy.

Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Sara Weschler Weschler
ID:
Deep Roots and Bitter Greens: Legacies of Colonial-Era Forced Displacement in Western Acholiland
REFNo: SS419ES

For my Master’s thesis research I studied the way British colonial officials used Sleeping Sickness control measures to justify the forced relocation of the entire population of western Acholiland between 1911 and 1920. For my PhD dissertation research, I will use qualitative interview methods to explore how the history of this early colonial-era forced displacement is remembered and understood in Acholiland today. I intend to examine what sorts of socio-cultural changes colonial-era displacement precipitated in Acholiland. At the same time, though, I hope to trace examples of cultural resilience and examine how Acholi culture and society recovered from these upheavals over the course of the intervening century.
USA 2020-02-19 2023-02-19 Social Science and Humanities Degree Award
Ian Munabi G
ID:
Birth related brain injury in Ugandan full term neonates
REFNo: HS551ES

Objective 1: To determine the association between foetal head moulding and hypoxic ischemic encephalopathy following spontaneous vaginal delivery.

Secondary objective:
Objective 2a: To determine the foetal factors (including foetal weight, infections, head circumference and birth order), associated with hypoxic ischemic encephalopathy following spontaneous vaginal delivery with foetal head moulding

Objective 2b: To determine the maternal factors (including maternal body mass, dietary patterns, gut microbiome, parity, social economic status and birth experience), associated with hypoxic ischemic encephalopathy following spontaneous vaginal delivery with foetal head moulding
Uganda 2020-02-19 2023-02-19 Medical and Health Sciences Non-degree Award
Milton Rwangire
ID:
Revitalizing Indigenous Knowledge: Integrating Indigenous Agricultural Knowledge into Modern Agricultural Practices for Sustainable Rural Household Food Security in Uganda
REFNo: SS233ES

Establish how indigenous agricultural knowledge and modern agricultural practices can be mainstreamed to enhance food security in Isingiro District 2. Analyze the existing forms and practices of modern agricultural practices and their contribution to food security in Isingiro District 3. Assess the importance of women’s secure land rights towards food security in Isingiro District 4. Establish the existing barriers to mainstreaming indigenous agricultural knowledge along modern agricultural practices in food security programmes in Isingiro District
Uganda 2020-02-11 2023-02-11 Social Science and Humanities Degree Award
Lydia Nakiyingi
ID:
Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for drug-sensitive Tuberculosis (TRUNCATE-TB)
REFNo: HS336ES

To test the hypothesis that the TRUNCATE-TB management strategy is non-inferior to the standard TB management strategy assessed by the proportion of patients with unsatisfactory outcome at 2 years (96 weeks) after randomisation.
Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Non-degree Award
Robert Kairania
ID:
HIV DISCLOSURE TRAJECTORIES AND ADHERENCE TO ANTIRETROVIRAL THERAPY AMONG CHILDREN IN MASAKA REGION, UGANDA.
REFNo: HS522ES

i. To assess the association between disclosure of HIV diagnosis and ART adherence among children on ART
ii. To examine the socio-cultural factors that influence disclosure of HIV diagnosis among children on ART
iii. To explore lived experiences before, during and after disclosure of HIV diagnosis among children on ART

Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Degree Award
Deborah Natumanya
ID:
A framework and its algorithms towards zero pulp paper based electronic examination process
REFNo: SIR21ES

Main objective
To attain a secure and Robust Electronic Examinations assessment Process for University Students
Specific objectives
To examine the usage and security of existing modes of assessment used in universities.
To design a Framework and its supporting Algorithms for Achieving a complete electronic university students assessment process.
To evaluate the usage and security of the developed framework and its algorithms.

Uganda 2020-02-11 2023-02-11 Engineering and Technology Degree Award
Yona Mbalibulha
ID:
Maternal Rh-Alloimmunization and Haemolytic Disease of the Newborn in South Western Uganda: alloantibodies profile and associated risk factors
REFNo: HS508ES

1. To establish the Rh antigen profile (i.e. C, c, D, E, and e antigens) among pregnant women in South Western Uganda.

2. To determine the prevalence of anti-Rh alloimmunization and the alloantibody identity among alloimmunized pregnant women in South Western Uganda.

3. To determine the anti-Rh antibody titers and the association to incidence of Hemolytic Disease Newborn in alloimmunized pregnant women

4. To identify risk factors for the presence of alloantibodies in pregnant women in south western Uganda

Uganda 2020-02-11 2023-02-11 Medical and Health Sciences Degree Award
Kim van Dijk
ID:
Jackfruit sharing between wild chimpanzees (Pan troglodytes schweinfurthii) living in a human-dominated landscape in Bulindi, Uganda.
REFNo: NS114ES

To determine how chimpanzees share jackfruit (e.g. patterns of active versus passive sharing, begging, harassment, and theft).
To determine which factors influence jackfruit sharing (e.g. female sexual swelling, harassment, social bonding, kin relations).
To map where chimpanzees forage for jackfruits.
To determine to what extent jackfruit sharing is similar to meat sharing in other chimpanzee populations.

Netherlands 2020-02-11 2023-02-11 Natural Sciences Degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
Treatment Outcomes of Difficult-to-Treat Drug resistant TB Patients: A retrospective evaluation of cases reviewed by the national TB consilium in Uganda
REFNo: HS452ES

Primary Objective 1: To determine the treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consilium in Uganda

Primary Objective 2: To compare the treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consilium in Uganda with those that have not been reviewed by the DR-TB consilium in Uganda

Secondary Objective: To establish predictors of treatment outcomes of difficult-to-treat DR-TB patients reviewed by the DR-TB consolium in Uganda

Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Judith Mutyabule NA
ID:
Exploring the influence of organisational culture: nurses' perspective on clinical leadership in a public hospital in Uganda
REFNo: HS480ES

To describe staff nurse clinical leadership
To explore the organisational culture influence on the structural environment of the staff nurses
To explain the barriers and facilitators of staff nurse clinical leadership
Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Degree Award
Samson Okello
ID: UNCST-2019-R001580
Cardiovascular risk factor profiles and outcomes in rural Uganda: The Bugoye Hypertension Improvement Project (B-HIP)
REFNo: HS487ES

1. To assess the baseline (at time of enrollment to BHIP) prevalence of various cardiovascular risk factors (obesity, dyslipidemia, and diabetes mellitus) in adults visiting the Bugoye Hypertension Improvement Project.
2. To determine incidence of sustained blood pressure control among persons with hypertension enrolled in BHIP.
3. To assess the costs of hypertension care in a Level III healthcare center in rural Uganda.
Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
Pharmaceuticals in the Environment: The emerging pollutant for surface water and food stuffs grown in Kampala City, Uganda
REFNo: HS530ES

General Objective
To assess existence of the PiE phenomenon, explore factors that may be contributing to it and propose short term and long term mechanisms to mitigate it in the KCCA

Specific Aims
•To establish magnitude of PiE in the KCCA
•To establish the factors that may be contributing to the PiE in KCCA

Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Abner Tagoola
ID: UNCST-2021-R013446
Saving young lives: Triage and management of sepsis in children using the point-of care Paediatric Rapid Sepsis Trigger (PRST) tool
REFNo: HS528ES

The purpose of this study is to develop and implement a digital trigger tool and electronic dashboard to guide frontline health workers in triaging children at facilities in LMICs with severe infection/suspected sepsis. This is with the goal of reducing time to diagnosis and treatment of critically ill children and ultimately reducing preventable child deaths from sepsis secondary to infectious disease.
Specifically, the research seeks to develop a prediction model and to perform clinical validation of a digital trigger tool to guide triage and treatment of children at health facilities in LMICs with severe infections/suspected sepsis.

Uganda 2020-02-07 2023-02-07 Medical and Health Sciences Non-degree Award
Menno Veen Niels Eduard
ID:
VULNERABILITY-RESILIENCE OF POTATO AND RICE FARMERS IN UGANDA TO SHOCKS: AN IMPACT ASSESSMENT OF THE INTERNATIONAL FERTILIZER DEVELOPMENT CENTERS (IFDC) REACH-UGANDA Project
REFNo: SS413ES

The objective of this study is threefold. First, to understand what are the shocks that rice and potato growing households in South-West and East Uganda are facing and what coping mechanisms households they use prior to and in response to shocks. Second, to quantify the vulnerability of households. Third, to measure the impact of the REACH-UGANDA project on households’ effectiveness of currently used coping mechanisms on well-being and the likelihood to fall into poverty.
Netherlands 2020-02-07 2023-02-07 Social Science and Humanities Degree Award
Johanna Meinecke
ID:
Consumer acceptance of novel healthy fruit and vegetable products in East Africa
REFNo: SS418ES

Factors influencing consumers’ perception of processed fruits and vegetables
(1) Examine sensory characteristics of jackfruit juice and cowpea leaf porridge by rural and urban consumers
(2) Elicit consumers’ willingness to pay for jackfruit juice and cowpea leaf porridge
(3) Relate consumers’ dietary and purchasing behaviour to acceptance of processed fruits and vegetables
(4) Analyse if information on products nutritional value, convenience and seasonality can enhance consumers acceptance
Germany 2020-02-07 2023-02-07 Social Science and Humanities Degree Award
Mercy Muwema
ID:
ASSESSMENT OF THE QUALITY OF PERINATAL CARE, AND DEVELOPMENT OF AN IMPROVED QUALITY OF PERINATAL CARE MODEL TO REDUCE PERINATAL DEATHS IN BUNYORO REGION
REFNo: HS483ES

Primary Objectives
1.To describe the health facility and health worker structures in place to support perinatal care at district hospitals in Bunyoro region.
2.To assess the prevalence and factors associated with poor quality of perinatal care at district hospitals in Bunyoro region
3.To assess the association between quality of perinatal care and birth outcomes at district hospitals in Bunyoro region
4.To explore care providers and client’s experiences on quality of perinatal care at district hospitals in Bunyoro region
5.To develop a context-specific quality of perinatal care model for Bunyoro region

Secondary objective
6.To assess the feasibility and acceptability of the context-specific quality of perinatal care model

Uganda 2020-02-06 2023-02-06 Medical and Health Sciences Degree Award
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