Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Taremwa Danison Danison
ID: UNCST-2024-R002981
AN OPTIMIZED ENSEMBLE DEEP LEARNING MODEL FOR MAIZE YIELD PREDICTION
REFNo: SIR375ES

General Objective of the Study

The general objective of the study will be to develop an optimized ensemble deep learning model to improve the accuracy of maize yield prediction, thereby enhancing decision-making by stakeholders in the agriculture sector.
Specific Objectives of the Study

i. To investigate the challenges of the current yield forecasting models and remote sensing technologies that will be used to generate variables for predicting maize yields using remote sensing data.
ii. To design and develop an optimized CNN-LSTM model using Bayesian approaches for the prediction of maize yields in Uganda.
iii. To evaluate the performance of the developed model for maize yield estimation.

Uganda 2025-04-02 8:32:18 2028-04-02 Engineering and Technology Non-Clinical Trial Degree Award
Moses Sembatya Nixon
ID: UNCST-2024-R015771
Baseline Study of Norms and Behavioral Drivers of Child Marriage and Female Genital Mutilation in Uganda
REFNo: SS3765ES

This study aims to provide crucial insights into the prevalence, drivers, and consequences of child marriage (CM) and female genital mutilation (FGM) in Uganda through a comprehensive baseline study. By assessing social norms, knowledge, attitudes, and practices related to CM and FGM, the study seeks to inform targeted interventions and policy decisions.
Uganda 2025-04-02 10:33:36 2028-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rogers Ssebunya
ID: UNCST-2025-R016712
Supporting Health System Readiness and Quality for Scaled Delivery of Self-Injectable Contraception: The Delivering Innovation in Self-Care (DISC) 2.0 Study Version 1.1
REFNo: HS5767ES

1. To describe health facility readiness to provide voluntary DMPA-SC SI within the existing contraceptive method mix in DISC-supported facilities in Uganda.
2. To describe quality of contraceptive counseling and client experiences among clients receiving injectables at DISC-supported facilities in Uganda.
3. To understand clients’ self-efficacy and confidence around DMPA self-injection immediately post-training and at 4-months follow-up in Uganda.
4. To improve understanding of DMPA-SC ‘take home’ units, including dispensation practices, provider and client preferences, storage, and usage, and disposal at initiation and 4-months follow-up.
Uganda 2025-04-02 10:31:32 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
Field Performance Evaluation of the Genbody ConfiSign HIV Self-Test in Uganda
REFNo: HS5760ES

To evaluate the field diagnostic performance and operational characteristics; usability, acceptability, and feasibility of the Genbody ConfiSign HIV ST in Uganda.

Specific objectives
a) To determine the field diagnostic accuracy (sensitivity, specificity, positive predictive value, and negative predictive value) of the Genbody ConfiSign HIV Self Test compared with the Wondflo HIV Self test (Guangzhou, China).

b)To evaluate the operational characteristics; feasibility, acceptability, and usability of the Genbody ConfiSign HIV ST in selected health facilities.

Uganda 2025-04-02 10:25:15 2028-04-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Odendi Gideon
ID: UNCST-2024-R002130
MENTAL HEALTH CHALLENGES, ADVERSE CHILDHOOD EXPERIENCES AND INTERPERSONAL PSYCHOTHERAPY AMONG ADOLESCENTS AT KAMPIRINGISA NATIONAL REHABILITATION CENTER, CENTRAL UGANDA
REFNo: HS5763ES

1. To determine the prevalence of mental health challenges (Depression, PTSD, and alcohol substance use disorders) and adverse childhood experiences (ACEs) among adolescents at Kampiringisa National Rehabilitation Centre (KNRC).
2. To examine the relationship between ACEs and mental health challenges, with social support as a mediator among adolescents at KNRC.
3. To explore the experiences and perceptions of adolescents regarding the effectiveness of existing counseling practices in reducing depressive symptoms among adolescents at KNRC.
4. To identify the socio-cultural factors, institutional policies, and individual characteristics that influence the feasibility, acceptability, and effectiveness of Group Interpersonal Therapy (Group IPT) in reducing depressive symptoms at KNRC.
5. To evaluate adolescents' experiences and perceptions of the feasibility, acceptability, and effectiveness of Group IPT compared to the existing counseling practices at KNRC.

Uganda 2025-04-02 10:00:01 2028-04-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Felix Bongomin
ID: UNCST-2020-R014224
Chronic Pulmonary Aspergillosis: Optimization of Therapy, Immunogenetic Screening, and Diagnosis in Uganda [CPA_OPTIONS_Phase I: A Prospective Cohort Study]
REFNo: HS5799ES

The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,The primary objective of this study is to establish a longitudinal cohort comprising individuals who have recently been diagnosed with CPA. The main aim is to comprehensively document various aspects of the disease progression and its impact on patients\' health over a span of 12 months.,
Uganda 2025-04-01 17:44:43 2028-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Stella Muyanja Zawedde
ID: UNCST-2021-R014037
The Integrated Management of Chronic Lung Illnesses in Uganda
REFNo: HS5728ES

Aim 1: To determine the prevalence of and factors associated with chronic respiratory illnesses e.g., asthma, chronic obstructive pulmonary disease among presumptive TB patients who test negative for TB on GeneXpert testing

Aim 2: (a) To determine the prevalence of, factors associated with post TB lung disease (PTLD) among patients who complete TB treatment (b) To determine the effect of post TB lung care on health related QoL among patients with PTLD

Aim 3: To determine barriers and facilitators for linkage to treatment for patients referred for chronic lung care

Aim 4: To document the cost per asthma/COPD case found during integrated community-based screening.
Uganda 2025-04-01 17:31:43 2028-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
george paasi
ID: UNCST-2020-R014619
THE CLINICAL SPECTRUM, GEOSPATIAL DISTRIBUTION AND GENETIC MODIFIERS OF SEVERE MALARIA AMONG CHILDREN WITH SICKLE CELL DISEASE IN EASTERN UGANDA.
REFNo: HS5714ES

i) To determine the effect of host RBC polymorphisms on the risk and severity of malaria.
ii) To determine the Geospatio-temporal distribution of the malaria-sickle cell disease syndemic in Uganda.
iii) To determine the clinical spectrum of severe malaria among children with SCA in eastern Uganda.

Uganda 2025-04-01 17:21:57 2028-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
ERICK SSEGUJJA
ID: UNCST-2021-R012964
Partnerships for Stronger Knowledge Systems in Africa (KNOSA): Lessons from Uganda
REFNo: HS5716ES

Specifically, the implementation research has the following objectives;
1. To characterise the nature and functioning of the different components of the current national knowledge system, ??with a focus on the health sector.
2. To explore constraints and challenges affecting the capacity of Uganda’s national knowledge systems.
3. To document and assess the current interventions to strengthen the national knowledge system?
4. To explore opportunities for strengthening the capacity of the national knowledge system to advance evidence-informed decision making in Uganda’s health sector.

Uganda 2025-03-25 11:14:05 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
INTEGRATED FEMALE SEXUALLY TRANSMITTED INFECTION TESTING FOR HIV EPIDEMIC CONTROL THROUGH PREP (IN-STEP)
REFNo: HS5715ES

a) To conduct an individually randomized effectiveness implementation trial of SRST plus cSTI testing to increase PrEP use among African women at high HIV risk.
b) To perform a mixed-methods, implementation science evaluation of female cSTI testing for improving PrEP use for HIV prevention.
c) To determine the most efficient, population-level female cSTI testing strategies to reduce HIV incidence in African settings.

Uganda 2025-03-25 11:13:20 2028-03-25 Medical and Health Sciences Clinical Trial Non-degree Award
Prudence Beinamaryo
ID: UNCST-2023-R007239
Developing a robust interdisciplinary-informed WASH framework for the prevention and elimination of the wicked public-health problem of schistosomiasis (WickedSchisto)
REFNo: HS5707ES

I. What are the true health, economic and societal impacts of schistosomiasis?
a) Characterise what quality of life means to individuals living in Schistosoma endemic areas in Cameroon and Uganda, and how this is affected by infections, WASH access, environmental, spatial, social and other determinants.
b) Measure the diverse impact of schistosomiasis on individual’s and household’s quality of life.
c) Quantify the economic costs associated with schistosomiasis to individuals and society.
d) Develop and validate a field-suitable morbidity marker for mapping and monitoring disease resolution.
II. What are the most cost-effective combinations of WASH and MDA interventions?
a) Test the hypothesis that MDA refusal, due to fear of side effects, is linked with latrine access.
b) Characterise relative contributions of existing WASH on reducing reinfection post MDA: risk to self.
c) Quantify environmental force-of-infection and the impact of ‘risk to self’ and ‘risk to
Uganda 2025-03-25 11:11:44 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Riley Derby Nicholas
ID: UNCST-2025-R017680
Impacts of early social life on social and physical development in mountain gorillas
REFNo: NS946ES

Study social and physical change in immature mountain gorillas in Bwindi Impenetrable National Park, in collaboration with Bwindi Gorilla Project, through combining behavioral, hormonal, and non-invasive growth measures
USA 2025-03-25 11:02:11 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Erika Sininärhi
ID: UNCST-2025-R017295
Physiological correlates of variation in personality traits in the banded mongoose Mungos mungo
REFNo: NS942ES

1) To determine the relationship between social rank, prenatal androgen exposure, and personality. 2) To investigate whether individual differences in facial thermal patterns are connected to personality, behaviour and stress reactivity.
Finland 2025-03-25 11:01:27 2028-03-25 Natural Sciences Non-Clinical Trial Degree Award
David Hayman T. S.
ID: UNCST-2023-R006403
One Health, multiple factors: an interdisciplinary investigation of emerging infectious disease
REFNo: NS924ES

Infectious diseases significantly impact global health, affecting both humans and animals. Zoonotic diseases, which are transmitted between animals and humans, pose particular risks in regions with high human-wildlife interaction. One such region is Uganda, specifically around Bwindi Impenetrable National Park (BINP), where communities live in close proximity to domestic and wild animals.

The objectives of this research are to:

Identify and quantify zoonotic pathogens in fecal samples from various animal species.

Assess pathogen prevalence across different species.

Analyze microbial community structures and antimicrobial resistance genes.
New Zealand 2025-03-25 11:00:19 2028-03-25 Natural Sciences Non-Clinical Trial Non-degree Award
Joan Mutyoba Nankya
ID: UNCST-2021-R010992
Using patient journey mapping approach to understand and improve post-abortion care within routine health care services
REFNo: HS4137ES


General objective

The general objective of this study is to use a journey mapping approach to understand client experiences as they navigate abortion services, and gaps in services, in order to improve PAC service delivery, client experiences and outcomes within the health care system.
Specific objectives

The specific objectives of the journey mapping approach include:

1. To document client experiences at different stages of post-abortion care-seeking.
2. To understand the current service provision processes for clients seeking post-abortion care services and identify gaps and unmet needs in these services.
3. To evaluate comprehensiveness of care and identify interventions to improve care.
4. To compare patient experiences with established standards of care

The specific objectives of the survey include:
1. To characterize the type and range of contraceptive and abortion-care services available for women who seek care at health facilities.
2. To determine whether women, including young women, receive comprehensive counseling on choices related to manual vacuum aspiration (MVA), medical abortion (MA) and contraception and which factors are related to receipt of such counselling.
3. To determine whether family planning and abortion services are provided with respect and compassion.

Uganda 2025-03-25 10:56:04 2028-03-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Karen Bailey M.
ID: UNCST-2024-R003544
Understanding invisible socio-environmental systems through pesticides across human-wildlife interactions
REFNo: SS3710ES

To model simulations of the interactions within the SES, illustrating the feedback mechanisms between pesticide use, environmental changes, and human-wildlife well-being,To quantify pesticide exposure and associated health outcomes in humans and wildlife, with a focus on spatial and temporal trends,To assess socio-economic and environmental factors influencing farmers\' decisions regarding pesticide use,To investigate the socio-environmental drivers and molecular-level impacts of pesticide use in a tropical forest-agricultural mosaic and develop strategies that balance agricultural productivity with biodiversity conservation among communities around the Kibale National Park ,
USA 2025-03-25 10:53:06 2028-03-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Integrating management of alcohol use, intimate partner violence, and menopausal transition into HIV care for women living with HIV in Uganda
REFNo: HS5750ES

To explore the unique health challenges faced by women living with HIV in Uganda related to intimate partner violence, menopausal transition, and alcohol use disorder (AUD), focusing on distinct age groups to inform targeted health interventions
Uganda 2025-03-19 13:02:04 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
Epidemiology of Malaria Infection in Sub-Saharan African Countries
REFNo: HS5638ES

To estimate the site-specific IR of P. falciparum infection by rapid diagnostic test (RDT) testing, overall and by age group (5-11 years, 12-17 years, 18-60 years) during the active detection of infection period.
Uganda 2025-03-19 12:57:39 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
Clonal Hematopoiesis: A Global Perspective on the Impact of CH on Alzheimer’s Disease in Sub-Saharan Africa
REFNo: HS5533ES

Main Objective
1. The aim of this proposed work is to compare the frequency and type of clonal hematopoiesis (CH) mutations in age-matched African American and Ugandan populations. We intend to determine the correlation between specific CH-associated mutations and development of Alzheimer’s Disease in both a Ugandan and African-American population.

Specific Objectives
1. Compare the frequency of CH in an elderly African American versus elderly Ugandan population.
2. Compare the types of CH mutations in an elderly African American versus elderly Ugandan population.
3. Determine the correlation between specific CH-associated mutations and the development of AD in a Ugandan population.
Uganda 2025-03-19 12:53:37 2028-03-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
STEVEN SEBBALE
ID: UNCST-2023-R006063
PARTICIPATION OF FEMALE DOCTORATE HOLDERS IN SCIENCE, TECHNOLOGY AND INNOVATION: AN EXAMINATION ON GENDER EQUITY, INCLUSIVITY AND INTERSECTIONALITY IN UGANDA
REFNo: SS3712ES

a) To examine the demographic and professional characteristics of female doctorate holders in Uganda
b) To assess the intersectional challenges faced by female doctorate holders in Uganda
c) To provide data-driven insights for integrating intersectionality into UNCST’s grants system
Uganda 2025-03-18 13:09:22 2028-03-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
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