Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ALPHONSINA MUJAWIMANA
ID: UNCST-2024-R015924
 PREVALENCE, PATTERNS AND FACTORS ASSOCIATED WITH NEURODEVELOPMENTAL DELAY AMONG YOUNG CHILDREN ATTENDING THE PAEDIATRIC OUT PATIENT DEPARTMENT CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS6113ES

General Objective To determine the prevalence, patterns, and factors associated with Neurodevelopmental Delay among young children attending the Paediatric OPD Clinic at Mbarara Regional Referral Hospital Specific objective 1.To determine the prevalence of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 2.To describe the patterns of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 3.To assess the factors associated with neurodevelopmental delay among children under five years at the paediatric OPD at MRRH
Uganda 2025-08-08 16:28:48 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Edirisa Kibuuka
ID: UNCST-2025-R016973
 Improving care and support of children with Cerebral palsy: Feasibility and Acceptability of Family care-group model in Kawempe division, Uganda
REFNo: HS6115ES

To evaluate coverage, appropriateness, adoption, acceptability, feasibility, fidelity and costs of implementing CP-family care-group model in improving supportive care of children with CP in peri-urban communities of Kawempe division,To assess perceived barriers and facilitators to implementing CP-family care-group model in improving care and support of children with CP at community, facility and division. ,We intend to roll-out cerebral palsy family care-group model in selected health facility catchment areas to reduce stigma/discrimination and improve supportive care of CP children in Kawempe division,
 Uganda 2025-08-08 16:27:42 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Lomonyang
ID: UNCST-2025-R017018
 Prevalence of perceived stigma and associated factors among patients with tuberculosis (TB). A cross-sectional study in Napak district, Karamoja region, Uganda.
REFNo: HS6105ES

Overall Objective: To determine the prevalence of perceived stigma and associated factors among patients with tuberculosis in Napak district, Karamoja region, Uganda. Specific Objective 1: To determine the prevalence of perceived stigma among patients with tuberculosis in Napak District. Specific Objective 2: To identify the factors associated with perceived TB stigma among patients with tuberculosis in Napak District.
Uganda 2025-08-08 16:26:22 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ESTHER NANSAMBA
ID: UNCST-2024-R002776
 SUCCESSION PLANNING PRACTICES, ORGANIZATIONAL CULTURE AND SURVIVABILITY OF HOTELS IN WESTERN UGANDA
REFNo: SS3479ES

i.To examine the effect of skill development on hotel survivability in western Uganda.
ii.To determine the effect of mentorship on hotel survivability
iii.To establish the effect of internal promotion on hotel survivability in western Uganda
iv.To determine the moderating effect of organizational culture on the relationship between succession planning practices and the survivability of hotels in western Uganda.
v.To determine the level of survivability of hotels in western Uganda.
 Uganda 2025-08-08 16:24:31 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Evaluation of a point-of-care molecular diagnostic test for brucellosis
REFNo: HS6127ES

Aim 1. Evaluate a point-of-care, rapid recombinase polymerase amplification, lateral flow detection assay (RPA-LF) for Brucella using clinical specimens from children and adults in rural southwestern Uganda with suspected brucellosis. Aim 1a: Determine the sensitivity, specificity, positive predictive value, and negative predictive value of the RPA-LF assay as compared to the current gold standard, blood culture, and quantitative PCR (qPCR). At Epicentre Uganda Research Laboratory, we will retrospectively perform the RPA-LF test on blood collected from patients presenting to health facilities in the Kazo and Kasese districts with malaria-negative fever for 1 week and one or more of the following symptoms: night sweats, headache, weight loss, fatigue, myalgia or arthralgia, and anorexia. We hypothesize that the RPA-LF assay can be successfully conducted in Uganda in a reference laboratory setting. In addition, we postulate that its sensitivity will be better than that of the currently available qualitative slide agglutination test and blood culture and will match that of qPCR. Aim 2b: Demonstrate the preliminary feasibility of RPA-LF test use at a peripheral health center in rural southwestern Uganda. We will conduct a small pilot sub-study to assess the acceptability and feasibility of test implementation by laboratory technicians at one of the study sites. We hypothesize that the assay can be successfully performed by local laboratory staff with minimal capacity investment. Aim 2: Explore the use of the RPA-LF assay for testing of cow and goat milk. For participants who test positive for brucellosis by slide agglutination test or blood culture, we will test self-collected pooled milk samples from their households using the Brucella Milk Ring Test and the RPA-LF assay and assess concordance between the two diagnostic methods.,The objective of this proposal is to preliminarily validate an RPA-LF assay for brucellosis that can be implemented in rural contexts in LMIC to improve brucellosis diagnosis and management.,
 Uganda 2025-08-08 16:22:39 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Musinguzi
ID: UNCST-2025-R017309
 Maintenance of Place Attachment and Future Aspirations: Towards a Model through Insights from Marginalised Indigenous Communities in Uganda
REFNo: SS4116ES

The study broadly aims to unravel the different forms of social-symbolic work Indigenous communities acting entrepreneurially (including business operators and owners) engage in to signal their relationship with their ancestral land to restore, preserve, and maintain cultural heritage for their future generation after displacement and their community’s aspirations. To achieve this objective, the study answers the research question below:

How do Indigenous communities act towards restoration, preservation, and maintenance of linkage to their cultural heritage for their future generation after displacement and their communities’ future aspirations?

 Uganda 2025-08-08 16:19:43 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Field Performance Evaluation of Kwiq HIV 1/2 Test kit in Uganda.
REFNo: HS6240ES

1.To describe the performance (sensitivity and specificity) of the KWIQ-TEST rapid test compared to the reference testing (Genscreen ULTRA HIV1/2 Ag/Ab EIA followed by the Murex diasorin HIV1/2 Ag/Ab combination).
2.To describe the performance (sensitivity and specificity) of the KWIQ-TEST rapid test, when compared to the national testing algorithm.
3.Estimate the proportion of inconclusive test results by KWIQ-TEST Test

Uganda 2025-08-08 16:18:18 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KEBIRUNGI ELIZABETH
ID: UNCST-2025-R017392
 ETHNOLBOTANICAL, PHYTOCHEMICAL AND NUTRITIONAL PROFILES OF COMMONLY USED HERBAL GALACTOGOGUES AMONG BREAST FEEDING MOTHERS IN KISORO DISTRICT
REFNo: NS981ES

To profile the Ethnobotanical, Phytochemical, and Nutritional composition of commonly used plant based galactagogues by breastfeeding mothers. 1.3.1 Specific objectives i. To document the plant species used as galactagogues and associated local knowledge ii. To assess the phytochemical composition of selected plant based galactagogues used by breastfeeding mothers. iii. To determine the nutritional composition of selected plant based galactagogues used by breastfeeding mothers
Uganda 2025-08-08 14:01:54 2028-08-08 Natural Sciences Non-Clinical Trial Degree Award
Stephen Loro Loro Simon
ID: UNCST-2024-R016624
 Enteral Feeding of premature neonates in Mbarara Regional Referral Hospital, Challenges and interventions
REFNo: HS6184ES

2. To develop a caretaker-led model of enteral feeding for premature neonates in MRRH using human-centred design approaches,To identify challenges that caretakers face while giving enteral feeding to premature neonates in MRRH. ,To establish the challenges that caretaker face while administering enteral feeds to preterm babies and develop a relevant intervention for care-taker led enteral feeding of premature neonates. ,
 South Sudan 2025-08-08 13:59:50 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Odongo Samuel
ID: UNCST-2024-R016137
 PATTERNS OF, FACTORS ASSOCIATED WITH, AND OUTCOMES OF SELF-MEDICATION AMONG CHILDREN AGED 1-59 MONTHS WITH ACUTE RESPIRATORY INFECTIONS AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS6188ES

3. To compare the seven-day in-hospital outcomes among children aged 1–59 months with ARI who have had self-medication by caregivers versus those who have not at MRRH.,2. To determine the factors associated with self-medication in children aged 1-59 months with ARI by caregivers at MRRH,1. To describe the patterns of self-medication among children aged 1-59 months with ARI by caregivers at MRRH.,To determine the patterns of, factors associated with, and in-hospital outcomes of self-medication in children aged 1-59 months with ARI by caregivers at Mbarara Regional Referral Hospital,
 Uganda 2025-08-08 13:58:48 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
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