Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Penlope Yaguma
ID:
Electricity access in Uganda's urban slums
REFNo: SS1036ES

Main objective: To investigate the electricity access challenges faced by households and businesses in Nankulabye slum, Kampala, Uganda
Specific Objectives
1. To identify the key socio-economic factors that influence electricity access in the slum
2. To model the daily load profile of a typical household and business in the slum
 Uganda 2022-05-18 9:32:25 2025-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Ponsiano Ocama
ID: UNCST-2019-R001799
 Prevention of Mother to child transmission of Hepatitis B virus in Uganda: the effect of Birth dose and antiviral therapy on neonatal transmission
REFNo: HS2201ES

Specific objectives
1. To determine prevalence of HBsAg in mothers attending antenatal care in the selected hospitals in Uganda
2. To determine the prevalence of HBsAg among 9-12month-old infants who received the HBV birth dose vaccination and the HBV 3 dose vaccinations and born to HBsAg+ve mothers who had viral load <20,000IU/ ML and never received TDF treatment.
3. To determine the HBsAg prevalence among 9-12month-old infants who received the HBV birth dose and the HBV 3 dose vaccinations and born to HBsAg+ mothers who had a viral load ?20,000 IU/ML and also received 3 months of TDF treatment.

Secondary objectives
a) Assess HBV viral load among pregnant women in different regions of Uganda.
b) Assess the predictor relationship between HBeAg and HBV viral load to transmission of the infection to unborn babies among pregnant women.

 Uganda 2022-05-18 17:20:32 2025-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muge Cevik
ID: UNCST-2022-R011548
 Unravelling the role of host microenvironment in the development of phenotypic resistance in Mycobacterium Tuberculosis
REFNo: HS2010ES

1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.

3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes

2. To identify risk factors for poor treatment response among patients with DM and TB 1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.

3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes

2. To identify risk factors for poor treatment response among patients with DM and TB


UK 2022-05-18 17:18:33 2025-05-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Stephen Tukwasibwe
ID: UNCST-2022-R011535
 Malaria drug and diagnostic resistance in refugee children in Uganda
REFNo: HS2164ES

1. Compare the prevalence of malaria parasitemia in refugee children arriving at Kyangwali and Adjumani reception centers and nearby non-refugee populations
2. Compare the prevalence of Pf mutations associated with resistance to key antimalarials between refugee and non-refugee populations
3. Compare the prevalence of Pf HRP-2 gene deletions that mediate diagnostic resistance between refugee and non-refugee populations
4. Compare Pf malaria parasites genetic relatedness between parasites isolated from newly arriving refugee children and those in refugees already in camps and in surrounding populations

 Uganda 2022-05-18 17:05:19 2025-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
National Telephone Survey to understand public opinions about governance, public services, social and economic conditions of ordinary Ugandans.
REFNo: SS1244ES

1.To gather Ugandan adults’ attitudes on issues such as economic and living conditions, access to services, and governance.

2.To compare the demographic results from this mixed mode sampling approach with census data, as a means of validating this innovative sampling and data collection approach.

 Uganda 2022-05-17 9:18:06 2025-05-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
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