Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Susan Babirye
ID: UNCST-2021-R013201
Analysis of formal and informal institutions of socializing places and their role in shaping vulnerability to HIV: a case of young people (15-24 years) working in socializing places in Uganda
REFNo: HS1536ES

This study aims to analyze formal and informal institutions of socializing places and their role in shaping vulnerability to HIV using a case of YPSP in Uganda. The specific objectives are:
1. To profile socializing places in Uganda and the young people who work in such places
2. To explore the formal and informal institutions of socializing places and their influence on HIV risk and vulnerability of YPSP
3. To determine how YPSP navigate workplace rules and procedures that expose them to HIV risk and vulnerability
4. To explore compliance gaps of the formal and informal institutions of socializing places with the existing laws and opportunities for reducing youth vulnerability to HIV in socializing places

Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
PURPOSE 1: GS-US-412-5624/ A Phase 3, Double-Blinded, Multicenter, Randomized Study to Evaluate Safety and Efficacy of Twice Yearly Long-Acting Subcutaneous Lenacapavir, and Daily Oral Emtricitabine/Tenofovir Alafenamide for Pre-Exposure Prophylaxis in Adolescent Girls and Young Women at Risk of HIV Infection. Version 2.0, dated 10 March 2021.
REFNo: HS1920ES

1. Primary Objectives i) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection. 2. Secondary Objectives/ end points i) To compare the efficacy of LEN with F/TDF for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection in participants adherent to LEN. iii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection in participants adherent to F/TAF. iv) To compare the efficacy of F/TAF with F/TDF for HIV PrEP in AGYW at risk of HIV infection. v) To evaluate the safety and tolerability of LEN, F/TAF, and F/TDF for HIV PrEP in AGYW at risk of HIV infection. vi) To evaluate the safety and tolerability of LEN and F/TAF for HIV PrEP in AGYW ≥ 16 to < 18 years of age who have sex with male partners and are at risk for HIV infection. 3. Exploratory objectives i) To assess the adherence rate to LEN as assessed by on-time LEN injection ii) To assess LEN plasma levels iii) To assess the adherence rate to F/TAF and F/TDF using intracellular TFV-DP levels in DBS. iv) To evaluate the acceptability of a once every 26 weeks LEN injection for HIV PrEP in AGYW at risk of HIV infection. v) To assess LEN plasma levels during pregnancy. vi) To explore concentrations of hormonal contraceptives in LEN participants.
Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Clinical Trial Non-degree Award
Julie Teichroeb Annette
ID:
Social decision-making in Angolan colobus (Colobus angolensis ruwenzorii) and vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo
REFNo: NS131ES

Understanding the effects of social constraints on group size and composition, movements, and foraging decisions.
Canada 2021-11-24 2024-11-24 Natural Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Enhancing immunity to malaria in young children with effective chemoprevention
REFNo: HS1763ES

To compare the incidence of malaria from 4 weeks to 4 years of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

To compare the incidence of malaria from 2-4 years of age among children randomized to receive IPT in childhood (IPTc) with monthly DP from 8 weeks to 1 year of age vs. monthly DP from 8 weeks to 2 year of age vs. no IPTc.

To compare innate and adaptive effector and regulatory responses between children randomized to different IPT arms.

Uganda 2021-11-24 2024-11-24 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Viga Emmanuel
ID:
MORAL AND SOCIAL DIMENSIONS OF ACCOUNTABILITY IN CIVIC HUMANITARIANISM: RELATIONAL AID AMONGST SOUTH SUDANESE REFUGEES IN UGANDA
REFNo: SS832ES

This research will majorly attempt to answer the question How is accountability of relational aid in civic humanitarianism conceptualized and managed in protracted crisis. This will be achieved by answering the following sub questions:- 1. What differentiates civic humanitarianism from mainstream humanitarian actors? 2. What is relational aid within civic humanitarianism? and how is accountability understood within the concept of relational aid? 3. What are the accountability practices in civic humanitarian aid? 4- How do different accountability forms influence aid delivery?
Uganda 2021-11-23 2024-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
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