Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sheila Ampaire
ID: UNCST-2021-R012468
 Baseline Review of Safety Monitoring and Reporting in the conduct of clinical Trials in Uganda
REFNo: HS5028ES

2. To understand the barriers and facilitators of safety monitoring and reporting in clinical trials in Uganda.,1. To evaluate the safety reporting system in the conduct of clinical trials in Uganda.,
 Uganda 2024-10-04 10:03:52 2027-10-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekubugu
ID: UNCST-2019-R001365
 Prevalence of Oral Human Papillomavirus and HIV-infection in priority populations in South Central Uganda: a pilot study
REFNo: HS4937ES

Objective 1: Estimate the prevalence of HIV and OHPV and their impact on oral health conditions in Rakai and neighboring districts in South Central Uganda.
(a) Estimate the prevalence of HIV and OHPV infection;
(b) Estimate the prevalence of oral diseases (pre-cancerous lesions, oropharyngeal cancer, periodontal disease, dental decay);
(c) Estimate the extent to which OHPV, HIV, and OHPV/HIV co-infection is associated with an increase in the prevalence of oral diseases.



Objective 2: Identify the barriers to accessing oral health services among fisherfolk participating in Rakai and neighboring districts in South Central Uganda.
a) Explore the key perceived barriers to healthcare services, including STI and oral health services;
b) Explore the level of oral health understanding among community members;
c) Explore the pathways community members use to access oral health care services,
d) Identify environmental, personal, sexual, and other risk factors associated with the prevalence of common oral conditions, including tooth decay, periodontal problems, and OHPV.

 Uganda 2024-09-27 22:19:07 2027-09-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Micheal Mutyaba Raymond
ID:
END OF PROGRAM EVALUATION FOR THE CITY WIDE INCLUSIVE SANITATION PROGRAM
REFNo: SS3202ES

a) Assess progress and Impact: the study aims at evaluating the progress made by the CWIS project in achieving its stated objectives and assess the impact of project interventions on targeted communities and institutions. This will involve examining whether the project has effectively increased access to improved onsite sanitation services, particularly for underserved urban poor households, public institutions, and transient populations; and
b) Provide recommendations for future Interventions: Based on the evaluation findings, formulate actionable recommendations for future sanitation interventions in Kampala and neighboring municipalities. These recommendations will aim at enhancing the effectiveness, efficiency, and sustainability of sanitation service delivery, contributing to the broader goal of urban transformation and improved public health outcomes.

 Uganda 2024-09-27 22:16:36 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Vivian Najjuka NA
ID:
Health Information Seeking Behavior of People Living With Vitiligo in South Western Uganda
REFNo: SS3061ES

1. To establish the health information seeking practices for People Living with Vitiligo in South Western Uganda. 2. To determine the level of satisfaction with the health information sources by People Living with Vitiligo in South Western Uganda. 3. To identify the challenges encountered by People Living with Vitiligo in South Western Uganda, while seeking for health information on Vitiligo condition. 4. To explore interventions for enhancing health information access for coping with the Vitiligo condition in South Western Uganda.,The study seeks to explore the health information seeking behavior of People Living with Vitiligo in South Western Uganda and to propose interventions for enhancing HI access for coping with the Vitiligo condition.,
 Uganda 2024-09-27 22:09:53 2027-09-27 Social Science and Humanities Non-Clinical Trial Degree Award
Mikiko Nihimura
ID:
Exploring “Actionable Information” for Learning Improvement in Rural East Africa: A Positive Deviance Approach
REFNo: SS3226ES

To explore effective channels of information sharing towards improving education outcomes at child, household, and school levels.,To understand how parents and schools obtain and use information for pupils’learning at home and school,To understand how parents and schools obtain and use information for pupils’learning at home and schoolto explore effective channels of information sharing towards improving education outcomes at child, household, and school levels.,
 Japan 2024-09-27 22:07:58 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
JAMES  SSENFUUMA THOMAS
ID: UNCST-2023-R005484
 2REST Responsibilities for Resilience Embedded in Street Temporalities: mapping street youth lived resiliences through analysis of secondary data
REFNo: SS3217ES

To analyse the GUOTS data set using a multisystemic resilience framework to street life experiences


To explore the data set longitudinally using a breadth and depth approach to understand temporal changes in young people’s lives, across diverse urban contexts, for creating interventions that develop as young people grow up


To explore with stakeholders, how the analysed evidence base can support young street people and inform policy and practice across diverse African and global contexts
 Uganda 2024-09-27 22:04:28 2027-09-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 SMART (Smallpox vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)
REFNo: HS4726ES

Co-Primary objectives Co-primary: 1) To assess the effectiveness of the Smallpox vaccine in preventing RT-PCR confirmed Mpox infection among contacts of confirmed Mpox infection 2) To assess the effectiveness of the Smallpox vaccine in reducing the severity of symptoms; measured as symptom severity score, based on 12 symptom items (16) each assigned a score of 0 to 5 for a total measure of 0 to 60. These co-primary objectives will be evaluated during the first 28 days after randomization.
 Uganda 2024-09-27 14:06:23 2027-09-27 Medical and Health Sciences Clinical Trial Non-degree Award
Joyce Nakatumba-Nabende
ID: UNCST-2020-R014244
 Establishment of the Makerere University Centre for Artificial Intelligence and Data Science (Mak-CAD)
REFNo: SIR402ES

1. Advance research and innovations in priority Artificial Intelligence for development (AI4D) areas, which include; AI in Healthcare, AI in Agriculture, Natural Language Processing, and AI for environment and climate challenges.
2. Train MSc and PhDs in thematic AI4D areas
3. Enhance AI4D impact through research translation and collaborations

 Uganda 2024-09-27 13:00:42 2027-09-27 Engineering and Technology Non-Clinical Trial Non-degree Award
Joel Ogwang
ID: UNCST-2022-R009783
 Initiating cattle health genomics research and applications in Uganda
REFNo: A462ES

1) Provide insight into the genetic composition and diversity of Ugandan cattle through the sampling and analysis of genotypes across multiple Ugandan farms.
2) Linking the genetic data with health data that are already being collected to pilot the utility of the LUNDA platform to facilitate future research and knowledge exchange in cattle health and productivity genomics.
3) Develop a roadmap for future collaborative research in cattle genomics in Uganda.
 Uganda 2024-09-27 12:58:24 2027-09-27 Agricultural Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Field performance evaluation of the Point of Care Afinion HaemoglobinA1c test (HbA1c) as a diagnostic tool for Diabetes Mellitus (DM) in people living with HIV/AIDS in Uganda.
REFNo: HS4523ES

To determine the operational characteristics a POC afinion device in HBA1C testing by the users.,To determine the feasibility and acceptability of integrating HbA1c as a diagnostic and monitoring tool for DM among PLHIV and TB/HIV patient.,To determine the accuracy of Afinion Hemoglobin A1c test (HbA1c) POC device in diagnosing and monitoring treatment in DM patients LWHIV Iin Uganda in comparison with Cobas C311 as a gold standard.,To evaluate the field performance of the point of Care Afinion Hemoglobin A1c test (HbA1c) as a diagnostic tool for Diabetes Mellitus (DM) in people living with HIV/AIDS.,
 Uganda 2024-09-25 15:02:46 2027-09-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GLORIA  GERIA Margaret
ID: UNCST-2024-R002971
 EXPLORING THE IMPLEMENTATION OF GROUP LEARNING IN PRIMARY SCHOOLS: A CASE OF MITYANA DISTRICT
REFNo: SS3100ES

Research Objectives
1.To identify the strategies employed by teachers in forming groups to facilitate group learning in selected primary schools in Mityana district.

2.To examine the perceptions of teachers regarding the implementation of group learning in primary schools.

3.To investigate the experiences of learners in the context of group learning in selected primary schools in Mityana district.

 Uganda 2024-09-25 13:42:18 2027-09-25 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 RightSign® HIV 1.2.O Rapid Test Cassette (Whole Blood/Serum/ Plasma) - Diagnostic sensitivity & diagnostic specificity, specimen equivalence, precision and qualification of usability.
REFNo: HS4998ES

4) To demonstrate the usability of this rapid diagnostic test (RDT) when performed by the intended users. It will be assessed whether the intended users comprehend all key messages from labelling and packaging (i.e. label comprehension study) and whether they can correctly interpret pre-determined test results (i.e. result interpretation study).,3) To estimate the precision (repeatability and reproducibility) of the RightSign® HIV 1.2.O Rapid Test Cassette (Whole Blood/Serum/Plasma) according to WHO TSS-1 Part 1: 1.3.1.,2) To demonstrate the equivalence of serum, plasma (EDTA-K2), venous whole blood (EDTA-K2) and fingerprick whole blood collected from HIV positive patients according to WHO TSS-1 Part 1: 1.1.1.,1) To establish the diagnostic sensitivity and diagnostic specificity of the RightSign® HIV 1.2.O Rapid Test Cassette (Whole Blood/Serum/Plasma) in plasma samples according to the WHO TSS-1 part 2.1.,
 Uganda 2024-09-25 13:23:10 2027-09-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
TOM OGWANG
ID:
The lived experiences of severe Covid-19 Survivors treated in Covid-19 treatment unit at Lira Hospital.
REFNo: HS4906ES

To explore the coping strategies employed by Survivors of Severe COVID–19 disease treated in Lira Hospital-isolation unit,To describe the lived experiences of survivors of Severe COVID–19 disease treated in Lira Hospital-isolation unit.,To explore the lived experiences and coping strategies of Survivors of Severe COVID–19 disease treated in Lira Hospital. ,
 Uganda 2024-09-25 13:07:57 2027-09-25 Medical and Health Sciences Non-Clinical Trial Degree Award
EVA NATUKUNDA
ID: UNCST-2020-R014330
 An Open-label, Single-arm Study to Provide Continued Access to Study Drug to Participants Who Have Completed Pediatric Clinical Studies Involving Gilead HIV Treatments
REFNo: HS4706ES

To provide Continued Access to Study Drug to Participants Who Completed Pediatric Clinical Studies Involving Gilead HIV Treatments
Uganda 2024-09-25 12:50:13 2027-09-25 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nakubulwa Kiwanuka
ID:
An investigation of Predictors of Brucellosis infection in Nakasongola District, central Uganda
REFNo: HS4967ES

i) To investigate the predictors of Brucellosis infection in Nakasongola District. ii) To investigate the barriers and facilitators of infection control measures for Brucellosis and give recommendations for disease control. iii)To examine the barriers and facilitators utilization of the One Health approach in Nakasongola District.
Uganda 2024-09-24 9:57:52 2027-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Diane Kabanyana
ID: UNCST-2024-R003450
 Evaluating the impact of VSLA-led water funds on handpump functionality and safe WASH behaviors in Kabarole District. RefNO:UCUREC-2024-923:
REFNo: SS3109ES

To examine the influence of VSLAs with water funds on the adoption of safe WASH (Water, Sanitation, and Hygiene) behaviors within communities. This includes determining whether communities with a water-fund VSLA show increased receptiveness to sanitation and hygiene promotion and exhibit higher rates of chlorination, safe water storage, handwashing, and latrine use.,To assess the impact of VSLA-led water funds on communities’ expenses for handpump maintenance and the functionality of handpumps. Specifically, this involves evaluating whether communities with active VSLA-led water funds collect higher financial contributions from water users, allocate more funds to handpump upkeep and repairs, and achieve better handpump functionality, as indicated by fewer days of downtime and enhanced user convenience (e.g., improved pump capacity and reduced leakage),
 Rwanda 2024-09-23 13:58:45 2027-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samuel Kiwanuka  Lubega
ID:
PREVALENCE OF WORK-RELATED MUSCULOSKELETAL DISORDERS AMONG KYAMBOGO UNIVERSITY STAFF
REFNo: HS4890ES

i) To investigate on the common work-related musculoskeletal disorders of Kyambogo
University staff.
ii) To determine the relationship between physical activity levels and work-related
musculoskeletal disorders among Kyambogo University staff.
iii) To establish the relationship between psychosocial factors and work-related
musculoskeletal disorders among Kyambogo University staff.
 Uganda 2024-09-23 13:51:40 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edmund Okello
ID:
INCIDENCE, TIME TO TREATMENT INTERRUPTION AND ASSOCIATED FACTORS AMONG TB PATIENTS IN PAKWACH DISTRICT, WESTNILE REGION, UGANDA
REFNo: HS4834ES

To determine the health systems factors associated with treatment interruption among TB patients in Pakwach district,To determine the socio-demographic factors associated with treatment interruption among TB patients in Pakwach district.,To determine the patient factors associated with treatment interruption among TB patients in Pakwach district.,To determine the incidence and the median time to treatment interruption among TB patients in Pakwach district.,To determine the incidence, time to treatment interruption and associated factors among TB patients in Pakwach district.,
 Uganda 2024-09-23 13:49:57 2027-09-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Hopwood
ID: UNCST-2022-R010178
 Sustainable tree use in Acholi, northern Uganda: A post-colonial approach to protecting an African community and environment
REFNo: SS3036ES

To use, develop and analyse the collaborative autoethnography method as a post colonial approach to research.,To evaluate strategies for influencing commuities on sustainable use fo natural resources.,To explore the influences of public authorities on communities in respect of natural resource use.,To understand the relationship between different public authorities and natural resources.,To understand the customary ownership of natural resources in Acholi.,To design a communications strategy around how domestic use of natural resources, especially trees, can be sustainable.,
 UK 2024-09-23 13:46:41 2027-09-23 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Nsubuga
ID: UNCST-2021-R012063
 Hospital Based Sentinel Surveillance of Adverse Events of Special Interest (AESI) after Vaccination with COVID-19 Vaccines in Uganda
REFNo: HS4771ES

1. Identify and describe successes and challenges experienced by Uganda during vaccine safety HBSSS planning, development, and implementation phases,3. Document implementation process and lessons learned to inform global vaccine safety partners on the use of HBSSS in low- and middle-income settings,2. Assess feasibility of using HBSSS to generate improved data on adverse events of special interest (AESI) conditions in Uganda (including background rates),1. Assess benefits and consequences of HBSSS implementation on existing vaccine safety surveillance practices in Uganda (i.e., reporting, investigations, causality assessments),
 Uganda 2024-09-23 13:44:46 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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