Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Julian Benedict Kuttig
ID: UNCST-2025-R018435
Youth Participation, Representation, and Civic Engagement in the Context of Social Cohesion: The Case of Uganda Martyrs University Nkozi and Rajshahi University, Bangladesh.
REFNo: SS3956ES

1. To investigate how student civic engagement contributes to social cohesion within university and local communities. 2. To understand the factors that shape student civic agency, including cultural, institutional, and policy influences. 3. To explore how lessons learned from diverse contexts can challenge the global North/South dichotomy and provide transferable insights into fostering social cohesion. 4. To shed light on the unique spatial and social dynamics of secondary cities as sites of youth civic engagement, offering a counterbalance to strictly urban- or rural-centric research.
Germany 2025-06-20 8:26:29 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cornelius Sendagire
ID: UNCST-2021-R004351
Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients (PRoFLUID)––an International Multicenter Observational Cohort Study The PRoFLUID–investigators
REFNo: HS6063ES

3.1. General Objective To explore global practices in intravenous fluid and vasopressor therapy in invasively ventilated ICU patients. 3.2 Specific Objectives Describe the types and volumes of fluids administered in the first 3 and 7 days after initiation of invasive ventilation. Detail the timing, type, and duration of vasopressor and diuretic therapy. Assess daily urine output and cumulative fluid balances. Evaluate clinical outcomes (ventilation duration, ICU/hospital length of stay, and mortality). Compare practices across different geo-economic regions.
Uganda 2025-06-20 8:20:52 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ellen Asiimwe
ID: UNCST-2024-R002415
Academic demands and Mental Wellbeing of Upper Primary Learners in Uganda. A study of Government and Private Schools in Mukono Municipality.
REFNo: SS3902ES

To explore the learners’ experiences of extracurricular activities in Mukono municipality primary schools,To compare the effect of academic demands and mental wellbeing on upper class learners from government schools and private schools,To assess how the length of time (early start and late end) influences learners’ mental wellbeing,To establish how high expectations affect learners’ mental wellbeing, To assess the relationship between academic demands and mental wellbeing from of upper class learners in Mukono Municipality Schools.,
Uganda 2025-06-20 7:56:25 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rachel  Kabunga Rehema
ID: UNCST-2021-R005043
Investigating the Feasibility of Implementing an Automated Diabetic Retinopathy Screening Algorithm in Southwestern Uganda
REFNo: HS5979ES

To describe the existing AI-based DR screening algorithms and their infrastructure
requirements based on published scholarly evidence globally.
2. To assess the existing capacity within the health facilities to support the implementation of an
AI-based DR screening system in Southwestern Uganda,
3. To assess the performance of the most context-appropriate existing AI-based DR screening
algorithms in Southwestern Uganda.
Uganda 2025-06-20 7:50:07 2028-06-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Nyboer Ann
ID: UNCST-2023-R005929
Social license and access in aquaculture: documenting perceptions of nutritional, economic, and environmental risks and benefits in Lake Victoria's fisheries
REFNo: SS3903ES

(1) document stakeholder views on the environmental, economic, and nutritional risks and benefits, (2) quantify stakeholder proximity to environmental risks, and (3) examine how different farm types affect risks, benefits, and access to those benefits for various stakeholders
Canada 2025-06-20 7:47:42 2028-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda
REFNo: SS3990ES

Suubi4PrEP will examine the effect of a multilevel intervention, combining HIV risk reduction that incorporates sessions on PrEP, peer supporters with lived experiences to facilitate linkage to and continued care, and economic empowerment components targeting financial barriers associated with PrEP access, PrEP initiation, uptake and adherence among AGYW in Uganda. Study aims are:

Aim 1: Examine the impact of Suubi4PrEP on PrEP initiation (primary outcome); and PrEP adherence (secondary outcome).

Aim 2: Examine the effect of Suubi4PrEP on hypothesized mechanisms of change (financial stability, PrEP stigma, self-efficacy, depressive symptoms, and social support) and intervention mediation.

Aim 3: Use mixed methods to explore multi-level factors that influence PrEP initiation and adherence.

Aim 4: Assess the cost and cost-effectiveness of the interventions.

Uganda 2025-06-20 7:41:25 2028-06-20 Social Science and Humanities Clinical Trial Non-degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
Pediatric Epilepsy in Busoga Region, Uganda – current management and factors associated with drug adherence and seizure control
REFNo: HS6004ES

The overall aim is to assess the current ability to diagnose and manage childhood epilepsy in
health facilities at different levels in Busoga region, Uganda and to describe pediatric epilepsy
patients followed at a Ugandan regional referral hospital to identify factors associated with
seizure control and epilepsy drug adherence.
Uganda 2025-06-20 7:37:23 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jesca Audo Harriet
ID: UNCST-2019-R000209
STUDENT LEARNING ACTIVITIES IN BIOLOGY LESSONS AS MEDIATORS OF SELF-EFFICACY AND GENERIC SKILLS IN UGANDA’S NEW LOWER SECONDARY CURRICULUM
REFNo: SS3915ES

The following objectives will serve as the study's direction. 1.To determine the level of student learning activities designed for students during Biology lessons in the lower secondary schools. 2.To determine the level of acquisition of generic skills among students during Biology lessons in the lower secondary schools. 3.To investigate the relationship between self-efficacy and student learning activities during Biology lessons in the lower secondary schools. 4.To examine the relationship between self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary school. 5.To examine the relationship between student learning activities and generic skills acquisition among students during Biology lessons in in the lower secondary schools. To investigate the mediating effect of student learning activities in relation to self-efficacy and generic skills acquisition among students during Biology lessons in the lower secondary schools.
Uganda 2025-06-20 7:34:34 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
VAC52150EBL4006 entitled: “Prospective, Multi-country, Non-interventional, Case-control Study with Test-negative Controls to Estimate the Effectiveness of the Ad26.ZEBOV, MVA-BN-Filo Vaccine Regimen Against Ebola Virus Disease (EVD) in Real-world Setting
REFNo: HS6053ES

The primary objective of this trial is to estimate the vaccine effectiveness of the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen or a booster dose of Ad26.ZEBOV against polymerase chain reaction (PCR)-confirmed EVD in adults and children
Uganda 2025-06-20 19:06:06 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justus Turamyomwe
ID: UNCST-2025-R019115
A Morphosyntactic Analysis of Runyankore-Rukiga Associative Nominals
REFNo: SS3955ES

1. To examine how associative nominals are marked in Runyankore-Rukiga
2. To Explicate how Runyankore-Rukiga nominals are derived.
3.To establish the specific functions of associative modifiers in Runyankore-Rukiga associative constructions.
Uganda 2025-06-20 19:00:22 2028-06-20 Social Science and Humanities Non-Clinical Trial Degree Award
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