Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,731
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Richard Mayanja Weazher
ID:
cultural practice and consumption of indigenous iron artifacts of the Baganda people in Uganda
REFNo: SS2942ES

3. To analyze the extent to which indigenous knowledge of ironworks of the Baganda in Central and Southern Uganda has survived.,2. To examine the historical and contemporary relevance of Indigenous iron implements to the Baganda in Central and Southern Uganda.,1. To document the indigenous knowledge embedded in the design production of the indigenous ironworks of the Baganda in Central and Southern Uganda.,The purpose of this study is to document the cultural practice and consumption of the indigenous iron art forms of the Baganda in central and southern Uganda for posterity. ,
Uganda 2024-08-26 14:55:51 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Claire Norcross Valerie
ID: UNCST-2024-R004641
An observational study evaluating archived and emergent HIV drug resistance in people with a history of sub-optimal HIV control in East and Southern Africa
REFNo: HS4761ES

1. To describe archived resistance mutation patterns (major/minor mutations and minority variants) in adults in East and Southern Africa with a recent history of sub-optimal adherence to dolutegravir-based ART; through next-generation sequencing of pro-viral DNA 2. To describe emergent resistance patterns (major/minor mutations and minority variants) in people living with HIV (PLWH) who fail treatment with long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) and the implications for future treatment, and in those who experience blips on LAI-CAB/RPV, through next-generation sequencing on stored plasma 3. To identify predictors of treatment failure on LAI-CAB/RPV in PLWH in East and Southern Africa, and consider how these predictors can influence policy
UK 2024-08-26 14:52:18 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okimait
ID: UNCST-2019-R000095
We Can Work Baseline for Youth With Disability
REFNo: SS3023ES

To provide relevant recommendations and insights that will further inform the program design and adaptation during the implementation period.,To measure all goal, outcome, and output level indicators as a benchmark for purposes of setting performance targets and measurement of the program progress,The overall purpose of this baseline survey is to establish a benchmark of the program indicators across all five outcomes to inform implementation. This will enable systematic measurement of progress towards the intended results annually and at final evaluation,
Uganda 2024-08-26 14:45:41 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
Rapid Assessment of Bottlenecks Inhibiting the Scale-up of Evidence-based Family Planning Practices in Uganda
REFNo: HS4723ES

Broad objective To understand enablers and inhibitors to the scale-up of three EBPs (PPFP, task sharing/expansion, and SBCC) and FP broadly through a BNA approach to inform strategies that can accelerate the uptake of family planning services and programme implementation in Uganda. Specific objectives 1.To synthesize what is known about scaling up FP EBPs and broader FP in Uganda, including implementation status, alignment of guidance with national and international standards, and the lessons learned from successful implementation (including approaches that aim to address gender norms and inequalities) 2.To understand the perspectives of key stakeholders (policymakers, programme managers, healthcare managers, service providers and civil society) on the various health systems factors inhibiting the scale-up of the EBPs. 3.Build consensus among key stakeholders on the most important bottlenecks to EBP scale-up and on solutions that address the root causes inhibiting scale-up
Uganda 2024-08-26 14:41:30 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
What works to prevent and respond to childhood sexual violence in resource-constrained settings: The Case of the 3RT Model implemented by The Remnant Generation in Uganda
REFNo: SS3005ES

4. To study the contribution of girls’ agency in promoting social norms change to prevent childhood sexual violence.,3. To identify critical enablers for effective implementation of interventions to prevent and respond to childhood sexual violence.,2. To explore the role of communities in leading sustainable change for safe environments free from childhood sexual violence. ,To document the effectiveness of the 3RT model in preventing and responding to childhood sexual violence among adolescents in Uganda.,To scientifically examine what works in preventing and responding to childhood sexual violence in resource-constrained settings using the 3RT model of the Remnant Generation as a case. ,
Uganda 2024-08-26 14:40:04 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Warren Aryeija
ID:
Experiences of People with Infertility in Uganda: Empirical Study of Couples with Infertility Challenges at Selected Hospitals in Kampala City
REFNo: SS2807ES

1. Assess knowledge about the causes of infertility among infertile male and female couples. 2. Identify socio-economic challenges experienced by infertile male and female couples. 3. Examine the psycho-emotional impact of infertility on infertile male and female couples. 4. Explore Coping strategies used by infertile male and female couples in living and dealing with infertility. 5. Determine the Socio-demographic correlates of Coping Strategies adopted by infertile male and female couples.
Uganda 2024-08-26 14:21:31 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Monicah Agaba
ID: UNCST-2024-R004221
The Health-Beauty Paradox among Women in Mbarara City Uganda
REFNo: HS4708ES

iii. To characterise the cardio-metabolic profile of WRA.,ii. To document the risk behaviours and their factors related to these societal beauty perceptions.,i. To document societal beauty perceptions and their determinants.,To understand what, why and how the health-beauty paradox is so deeply entrenched in the culture.,
Uganda 2024-08-26 10:18:37 2027-08-26 Medical and Health Sciences Clinical Trial Degree Award
George William Ddaaki
ID: UNCST-2022-R009216
Exploring perceptions, concerns, and perceived benefits of pregnant women and those intending to become pregnant towards participating in HIV cure research.
REFNo: SS2866ES

a) To identify concerns and perceived benefits among women in south central Uganda regarding their participation in HIV cure studies.
b) To explore the perceptions and attitudes of pregnant women and those intending to become pregnant in south central Uganda towards participating in a study focused on impact of pregnancy on the HIV viral reservoir and HIV cure.

Uganda 2024-08-26 10:14:01 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Implementing comprehensive malaria surveillance at sentinel sites in Uganda
REFNo: HS4692ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda.
Uganda 2024-08-26 10:12:47 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
GENDER REFORMS AND POLITICAL SYSTEMS IN UGANDA
REFNo: SS2985ES

The broad objective is to put in context the emerging gender programming reforms in Uganda, particularly the persistent narrative that despite the success in policies that promote women in governance, leadership and employment roles, women voices continue to lag behind.

As a secondary objective, the survey also seeks to increase our understanding of how physical and psychological violence targeting political candidates impacts adult Ugandans’ willingness to engage in electoral politics.


Uganda 2024-08-22 16:38:35 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mutuzo Esther
ID:
Usability Context and Adoption of Human Capital Management Systems in Ugandan Public Universities: Application of the Unified Theory of Acceptance and Use of Technology
REFNo: SS2972ES

Purpose
This study aims to investigate the influence of usability context on the adoption of HCMS in Ugandan Public Universities by using variables from Venkatesh et al.’s (2003) UTAUT theory.

Objectives
The study will focus on the following objectives:
1. To investigate the influence of performance expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
2. To assess the influence of effort expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
3. To investigate the influence of social influence on Ugandan public university staff behaviour intention to adopt HCMS.
4. To examine the influence of facilitating conditions on Ugandan public university staff’s actual use of HCMS.
5. To investigate the influence of Ugandan public university staff behaviour intention on their actual use of HCMS.
6. To investigate the moderating effect of user background characteristics (gender, voluntariness of use, age, and experience) on the relationship between usability context constructs and the adoption of HCMS among Ugandan public university staff.

Research Questions
The study will focus on the following research questions:
1. What are the obstacles impeding the adoption of HCMS in Ugandan public universities, and how can they be addressed?
2. What are the enabling factors facilitating the adoption of HCMS in Ugandan public universities, and how can they be enhanced?

Uganda 2024-08-22 16:35:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jose Rubio Valverde Ricardo
ID: UNCST-2024-R003911
Evaluation of the Pathways out of Poverty (POP) project in the Kitagwenda and Rakai districts of Uganda
REFNo: SS3052ES


1. Assessing the achievement of objectives: The evaluation aims to assess whether POP\'s objectives are achieved, including increasing household income to $2.25/day, reducing the average household Poverty Probability Index score to 22 or less, and ensuring that 60% of households feel their quality of life has improved within 24 months of each cohort\'s initiation.

2. Estimating causal impact: On priority outcomes for HWG - including grow and net household income, household asset endowment, coffee revenue and profits, best practice adoption and yield – the goal is to determine whether it is possible to establish causal inference on the effects of the program on these variables.

3. Conducting heterogeneous treatment effects analysis: The evaluation will analyze variances in the estimated treatment effect across different demographic groups, with a focus on geographic, economic, social and gender factors.

4. Understanding pathways of change: Core to HWG’s agenda is identifying which project components are vital for driving primary outcomes. The evaluation will aim to dissect the project’s multifaceted initiatives to delineate the most impactful pathways tied to changes in income and agricultural productivity.

5. Determining the importance of coffee: With HWG placing a strong emphasis on the role of coffee in household income, the evaluation will focus on measuring how coffee-centered interventions contribute to the broader project outcomes, tying coffee profit and revenue analyses to holistic changes in income.

6. Identifying unintended consequences: The evaluation should also scrutinize potential negative impacts on the environment, health, human rights, community dynamics, and gender equity, such as the effects of agrochemical use, deforestation, community conflicts, labor issues, and changes in household dynamics and resource control.

7. Suggesting operational improvements: Finally, the evaluation should provide actionable insights and recommendations during the implementation period, to increase the efficacy of POP.

Netherlands 2024-08-22 16:33:12 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSEPH  MURANGIRA
ID:
STRATEGIC MANAGEMENT PRACTICES AND LEGAL CERTAINTY IN UGANDA JUDICIARY
REFNo: SS2917ES

i. To evaluate the effect of strategy formulation on legal certainty in Uganda Judiciary.
ii. To assess the effect of strategy implementation on legal certainty in Uganda Judiciary.
iii. To assess the effect of strategy evaluation on legal certainty in Uganda Judiciary.
iv. To investigate the effect of strategic control on legal certainty in Uganda Judiciary.


Uganda 2024-08-22 16:30:00 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability. "CPSP nr ASH-CPH 23-045"
REFNo: HS4685ES

The objective of this evaluation is to establish the performance of the HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series (TSS) for submission to WHO Prequalification – Diagnostic Assessment: TSS-13.,
Uganda 2024-08-22 16:24:28 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Anti-HCV Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability.
REFNo: HS4703ES

The objective of this evaluation is to establish the performance of the HCV Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series for submission to WHO Prequalification – Diagnostic Assessment: TSS-16 (2021 update).,
Uganda 2024-08-22 16:20:33 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Linda Grace  Alanyo
ID:
The Role of Social Capital in Enhancing the Reproductive Autonomy of Adolescent Girls in Uganda
REFNo: SS2627ES

To explore the perspectives of immediate caretakers and other stake holders on barriers and facilitators to Reproductive autonomy of adolescent girls,To Assess the Reproductive autonomy of Adolescent girls in Uganda and associated socio-ecological factors ,To synthesize evidence on factors associated with the reproductive autonomy of adolescent girls.,To understand the role of social capital in enhancing the Reproductive Autonomy of Adolescent girls in Uganda,
Uganda 2024-08-22 16:15:47 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
Promotion of a Safe Workplace Environment, Free from Gender-based Discrimination and Violence: A Policy Review and Action Research on the Prevalence of Workplace Gender Discrimination and Violence within the Agriculture, Tourism and Hospitality Sectors in the Rwenzori and Albertine Regions in Uganda
REFNo: SS2600ES

Develop action plans (1 per sector) based on research findings to address gender-based discrimination and violence, and create safe and inclusive work environments.,Identify support structures and mechanisms for work related Gender based discrimination and violence victims available in the region. ,Analyse existing policies and their gaps to address gender-based discrimination and violence at the workplace targeting selected sectors in Albertine and Rwenzori regions. ,To conduct action-oriented research on gender-based discrimination and gender-based violence (GBV) at the workplace targeting agriculture, tourism, and hospitality sectors in the Albertine and Rwenzori regions.,To contribute to the promotion of a Safe Workplace Environment, free from gender-based discrimination and gender-based violence.,
Uganda 2024-08-22 15:26:06 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kelsey Shaw
ID:
In-situ assessment and collection of fecal sludge from non-sewered sanitation containments: Linking demographic, environmental and technical parameters to microbial activity
REFNo: SIR275ES

The overall objective of this PhD project is to better understand and characterize anaerobic degradation pathways in containment of non-sewered sanitation systems (NSS) in resource constrained settings representative of both urban and rural areas. In view of this, the specific objective linked to this research pertaining to this ethics application is to understand the influence of demographic, environmental and technical (DET) data on measurable fecal sludge parameters as well as microbial community composition within NSS containment across variable geographic regions. The proposed project aims to answer the following specific research questions: - What are the effects and variations associated with physical location, use, and operating conditions on wastewater quality and microbial composition? - What is the relationship between location of sanitation system and behaviors associated with operational parameters? - Is there a link between main concentration gradients in containment and spatially analyzable factors (i.e., demographic, environmental and technical)?
Canada 2024-08-22 15:18:53 2027-08-22 Engineering and Technology Non-Clinical Trial Degree Award
Luke Nyakarahuka
ID: UNCST-2023-R008138
Surveillance and Research of Viral Hemorrhagic Fever Outbreaks in Uganda: Acute Case Investigation and Survivor Follow-up for Strategic Public Health Intervention
REFNo: HS2964ES

The primary objective is to enhance Uganda’s capacity to rapidly detect, diagnose, respond to, and prevent VHFs including those caused by Ebola, Marburg, CCHF, RVF, Sosuga, and other emerging viruses. To do this, it is critical to understand the incidence, distribution, risk factors for emergence and transmission, immunogenicity and clinical progression (including potential asymptomatic infection), and potential for transmission following clinical recovery of these diseases throughout Uganda, which will enable improved VHF case outcomes, identification of unknown chains of transmission, survivor monitoring, and strategic targeting of public health and animal health resources to prevent and control transmission of these high-consequence viruses.
Uganda 2024-08-22 15:14:36 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
Effect and implementation factors of a contextually adapted short message service or phone call intervention to reduce loss to follow-up among presumptive TB patients in North Central Uganda
REFNo: HS3000ES

1.To determine the proportion of pre-diagnosis LTFU among presumptive TB patients and influencing factors in North Central Uganda (Sub-study 1). 2.To explore stakeholder’s perceptions on use of an SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda and contextually adapt the interventions (Sub-study 2). 3.To assess the effect of a contextually adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda (Sub-study 3). 4.To explore factors that influence implementation of a locally adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in North Central Uganda (Sub-study 3). 5.To synthesize evidence on effectiveness of mHealth interventions to reduce LTFU in the TB presumption phase in LMICs (Sub-study 4)
Uganda 2024-08-22 13:00:28 2027-08-22 Medical and Health Sciences Clinical Trial Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."