Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Emmanuel Mfitundinda
ID: UNCST-2024-R015971
Surveillance for recurrence and residual cervical intraepithelial neoplasia using high-risk human papillomavirus testing at Kawempe National Referral Hospital in Uganda, 2025
REFNo: HS5795ES

To improve surveillance for residual and recurrent CIN during follow up of women attending Kawempe National Referral Hospital (KNRH) in Uganda Specific objectives (i) To determine the prevalence of hr-HPV among women with CIN and those without CIN at Kawempe NRH, January-November, 2025 (ii) Determine the diagnostic/prediction accuracy of hr-HPV compared to the standard cytology for residual or recurrent CIN of any grade. (iii) Determine factors associated with progression of any CIN to a higher grade CIN or invasive cervical carcinoma (iv) Assess the level of acceptance of hr-HPV screening in women treated for CIN among health workers in the women's clinic at Kawempe National Referral Hospital
Uganda 2025-08-26 16:02:41 2028-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamella Abwoyo
ID: UNCST-2024-R015875
Prevalence And Associated Factors Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli In Wet Markets In Lira District, Uganda: A One-Health Cross Sectional Study
REFNo: SS3917ES

1. To determine the prevalence and associated factors of ESBL-E.coli in chicken sold in wet markets in Lira District 2. To determine the prevalence and associated factors of ESBL-E.coli in wastewater sources in wet markets in Lira District 3. To determine the prevalence and associated factors of ESBL-E.coli in humans (chicken traders) in wet markets in Lira District
Uganda 2025-08-26 16:01:07 2028-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Oguttu Were
ID: UNCST-2024-R005275
Onchocerciasis infection status in patients with Nodding Syndrome and epilepsy in Madi-Mid North focus, Uganda
REFNo: HS6224ES

To determine the prevalence of Onchocerca volvulus infection in people with a history of Nodding Syndrome in Madi-Mid North, Uganda
Uganda 2025-08-26 15:55:47 2028-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kitonsa
ID: UNCST-2025-R018208
Investigating metabolic outcomes in African adults living with HIV after switching to injectable antiretroviral therapy
REFNo: HS6320ES

1. a) To compare changes in weight, body mass index, lipid profiles, and blood pressure, over one and two years among patients receiving 2-monthly long-acting cabotegravir and rilpivirine and compare this with those remaining on oral ART. b) To determine factors associated with changes in weight, BMI, lipid profiles, and blood pressure over the one- and two-year periods. 2. To describe the baseline glycaemic status of an African population with a history of suboptimal HIV control, and the change in HbA1c whilst on long acting cabotegravir and rilpivirine compared with patients remaining on oral dolutegravir - based ART through one and two years of follow-up. 3. To compare change in 10-year cardiovascular risk among patients on long acting cabotegravir and rilpivirine with those remaining on oral dolutegravir - based ART after one and two years of follow-up. 4. To quantify the impact of tenofovir disoproxil fumarate cessation on estimated glomerular filtration rate across one and two years of follow-up among patients receiving 2-monthly long-acting cabotegravir and rilpivirine compared with those remaining on oral ART. 5. To compare serum leptin and fasting insulin levels during follow-up in a subset of participants with significant weight gain and sample of similar participants without weight gain at 12 months.
Uganda 2025-08-26 15:48:19 2028-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
VIVIAN ARINAITWE
ID: UNCST-2024-R016282
Developing a Feasibility Framework for MedTech in Low-Resource Settings: A Case Study of the NeoNest Device in Mbarara District, Uganda
REFNo: SIR537ES

1.4.1. Main Objective
To evaluate the feasibility of implementing the NeoNest neonatal transport incubator in selected health facilities in Mbarara District, Uganda, and to develop a structured, context-specific feasibility assessment framework for introducing medical technologies in low-resource settings.
1.4.2. Specific Objectives
To assess current neonatal transport and thermal care practices in health facilities in Mbarara District.
To evaluate the simulated performance, usability, and acceptability of the NeoNest device in a controlled setting.
To identify barriers and enablers for the adoption and scale-up of the NeoNest device.
To develop and validate a feasibility assessment framework for medical technology deployment in low-resource settings, using expert consensus (e.g., Delphi ≥ 80% agreement).

Uganda 2025-08-26 15:46:45 2028-08-26 Engineering and Technology Non-Clinical Trial Non-degree Award
HELEN KEZIE-NWOHA EKENE
ID: UNCST-2024-R016104
Loalising National Gender and Climate Policy in Uganda
REFNo: SS4066ES

• To examine the extent to which global and national climate policies are leading to change at the local level, improving the lives of women and gender relations, including the distribution of resources.
• To co- produce knowledge with women, women’s organisations, community organisations and local government officials, about the effects of climate change on the lives of women and their communities; identify obstacles; and propose solutions and pathways to climate resilience.
• To use research evidence from the research to influence national level policy making

Nigeria 2025-08-26 15:44:37 2028-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wilson Ngonzi
ID: UNCST-2024-R016516
SMALL HOLDER FARMERS ADAPTATION STRATEGIES TO CLIMATE CHANGE IMPACTS IN KIBAALE, KAGADI AND KAKUMIRO DISTRICTS
REFNo: SS4100ES

To examine the temperatures, drought and precipitation climate change patterns that impacts small holder farmers adaptation strategies in Kibaale, Kagadi and Kakumiro Districts To examine the small holder farmers adaptation strategies to climate change impacts in Kibaale, Kagadi and Kakumiro Districts. To examine the small holder farmers adaptation strategies on accessing climate information and early warning systems in Kibaale, Kagadi and Kakumiro Districts
Uganda 2025-08-26 15:42:18 2028-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
MUGULUSI GIDEON
ID: UNCST-2025-R018401
SUSTAINABLE INDUSTRIALISATION ON JOB CREATION AND POVERTY REDUCTION IN UGANDA
REFNo: SS4147ES

Purpose of the Study
The general objective of the study is to examine the effects of sustainable Industrialization on job creation and poverty reduction in Uganda
1.3. 1 Specific Objectives
The following specific objectives will guide the study
(i) To examine the effects of Industrial Policy (IP) on job creation and poverty reduction in Uganda
(ii) To investigate the effects of Technological Innovation (TI) on job creation and poverty reduction in Uganda
(iii) To analyze the effects of Infrastructure Development (ID) on job creation and Poverty Reduction in Uganda.
(iv) To determine the effect of Human Capital Development (HCD) on job creation and poverty reduction in Uganda.
(v) To analyze the effect of environmental sustainability on job creation and poverty reduction in Uganda.
(vi) To evaluate the effect of social inclusion on job creation and poverty reduction in Uganda.
(vii) To examine the moderating effect of government support on Job creation and poverty reduction in Uganda

Uganda 2025-08-26 15:38:58 2028-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Micheal Segawa Collins
ID: UNCST-2025-R017185
EXPLORING HPV VACCINE UPTAKE AND ITS BARRIERS AMONG ADOLESCENT GIRLS AND YOUNG WOMEN IN URBAN SLUMS OF KAMPALA.
REFNo: HS6259ES

To determine the uptake of both doses of the HPV vaccine among adolescent girls and young women in the urban slums of Kampala.

To identify the barriers to the uptake of the HPV vaccine among adolescent girls and young women in the urban slums of Kampala

Uganda 2025-08-26 15:37:00 2028-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Louis Gorgone
ID: UNCST-2025-R019673
Socioendocrinology of female forest living olive baboons (Papio anubis)
REFNo: NS998ES

This research aims to explore the hormonal correlates of dominance, aggression, and affiliative (pro-social) behavior in female forest-living olive baboons (*Papio anubis*) at Kibale National Park, Uganda. Specifically, it investigates how female dominance rank, aggression, and social behaviors relate to physiological stress and aggression markers, measured through glucocorticoids and testosterone. By examining these relationships at multiple temporal scales, the study will shed light on the adaptive significance of social hierarchies and behaviors among females living in an ecologically stable forest environment, thus advancing the understanding of socioendocrine mechanisms underpinning female primate sociality.

USA 2025-08-26 15:34:30 2028-08-26 Natural Sciences Non-Clinical Trial Degree Award
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