Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Robert Newton Edward
ID: UNCST-2023-R006537
 International Prevalence Surveys of Helicobacter pylori in High and Low Risk Areas for Stomach Cancer Epidemiological iNvestigatIon of Gastric Malignancies – ENIGMA
REFNo: HS1891ES

Objectives of the research project: i. To estimate the age-specific prevalence of Helicobacter pylori infection as predictor of Gastric Cancer trends. ii. To investigate bacterial, host and environmental factors associated with differences between high and low Gastric Cancer risk areas. iii. To measure H. pylori antibiotic resistance to Metronidazole and Clarithromycin in the different geographic regions. iv. To further explore the association between H. pylori infection and child growth
UK 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
 Field Performance Evaluation of the Xpert® HIV-1 Viral Load assay for Viral Load (VL) monitoring in Uganda
REFNo: HS1977ES

To determine acceptability of the the Xpert® HIV-1 Viral Load assay by the study participants.,To determine changes in turn-around time and ease of clinic workflow integration,To determine the operational characteristics of the Xpert® HIV-1 Viral Load assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel ,To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the Xpert® HIV-1 Viral Load assay in comparison to a reference assay, Roche COBAS 8800 in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected. ,To evaluate the field performance of the Xpert® HIV-1 Viral Load assay in identifying virological failure (VF) in adults on ART. The performance will be compared to the reference assay, the Roche COBAS 8800 used at UNHLS. ,
 Uganda 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Designing an intervention to increase HIV self-testing uptake and clinic linkage among men in Uganda: A Discrete Choice Experiment
REFNo: HS1061ES

Aim 1: To pilot test two HIVST Discrete Choice Experiments on 1) distribution strategies and 2) linkage strategies to assess how well participants understand the questionnaire and inform final design.

Aim 2: To conduct a DCE to determine men’s preferred HIVST distribution strategy to increase uptake. We will assess men’s preference for mode of HIVST distribution (e.g. pharmacy, drug shop, clinic, partner, friend), pre-test support, and post-test support.

Aim 3: To conduct a DCE to determine men’s preferred intervention to increase clinic linkage for HIV care and prevention after HIVST. We will assess the potential of financial incentives, screening for other diseases, fast-track services, and peer navigators to motivate men to link to care.
 Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-degree Award
Samuel Meyerson
ID:
From the Kraals to the Markets: A Pastoral World Beyond the State in East Africa
REFNo: SS1045ES

1. To analyze the transnational networks that have connected Ateker communities in East Africa from the precolonial era to the present day. 2. To examine the historical relationships between Ateker communities and state structures in East African countries during the colonial and post-independence periods. 3. To use historical analysis to identify ways of fostering national integration and sustainable development in Karamoja.
Canada 2022-01-25 2025-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
FREDRICK MAKUMBI
ID:
Assessment of the Scale, Reach, Quality, and Cost of Service Delivery High Impact Practices in Family Planning in Uganda
REFNo: HS2005ES

To estimate the costs of implementing and sustaining service delivery, and identify the cost drivers, and efficiencies for selected HIPs in Uganda ,To assess the quality of services for selected service delivery HIPs, including policy-level intention and readiness of services to offer the HIP in Uganda ,To measure the current reach of selected service delivery HIPs to sub-populations by age, urban/rural location of service delivery points, and, if applicable, new FP users in Uganda,To measure the current horizontal and vertical scale of implementation of 3 service delivery HIPs in Uganda,The goal of this assessment is to develop and apply a replicable approach that measures the scale, reach, quality, and cost of HIPs, information which will help Uganda and other countries to critically analyze and maximize their investments in comprehensive FP strategies. ,
 Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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