Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Accuracy of Novel Diagnostic Tests for Detection of Tuberculosis in Adults: FEND for TB (“FEND-TB Adults”)
REFNo: HS1016ES

Primary Objectives
• To provide clinical specimens and data to FEND for TB researchers and their collaborators in order to determine the diagnostic accuracy and operating characteristics of investigational in vitro tuberculosis diagnostic assays and strategies
• For each participant, to conduct a pre-specified set of standard-of-care diagnostic tests in order to classify that participant’s status with respect to tuberculosis (reference standard).

Secondary:
• To gather parameter estimates for economic analyses

Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Optimizing approaches to implementing self-injection of DMPA-SC within the contraceptive method mix: a case of Uganda
REFNo: HS1087ES

AIM: The aim of the study is to optimize approaches to implementing self-injection of DMPA-SC among various contraceptive choices and answer crucial questions about whether SI can enable contraceptive use for women who face barriers and enhance empowerment in Uganda.
4.1 Objectives:
1. Identify who may be the most likely to benefit from the scale-up of DMPA-SC self-injection.
2. Develop effective approaches for supporting the use of DMPA-SC self-injection in a way that helps women overcome barriers and optimize facilitators to contraceptive decision-making and use.
3. Understand the role self-injection can play in promoting empowered contraceptive decision-making and autonomy.
NB: SPECIFIC OBJECTIVES OUTLINED BELOW FORM PHASE ONE OF THE STUDY AND FOCUSES ON OBJECTIVE 1.
4.11 Specific objectives for Phase one:
I. To elucidate the barriers and facilitators to contraceptive decision-making and use among different groups (including identification of groups who face the most barriers), and identification of women with the most interest in SI across study sites of Mayuge and Oyam districts in Uganda.
II. To better understand the context within which DMPA-SC is being rolled out and identify where opportunities lie to conduct research into women’s interest and experience with the method alongside implementation efforts.


Uganda 2020-12-02 2023-12-02 Medical and Health Sciences Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
Understand the impact of COVID-19 on the ability of women to access family planning services and products in Uganda
REFNo: HS1031ES

1) To track the utilization of RH/FP and MNCH services including antenatal care (ANC) and postnatal care (PNC)
2) To describe the availability of supplies, commodities and human resources for these services
3) To document innovations and adaptations that the government of Uganda (GOU) and NGOs are implementing to ensure the continuity of services

Uganda 2020-12-01 2023-12-01 Medical and Health Sciences Non-degree Award
Julie Abimanyi-Ochom Abimanyi-Ochom
ID:
IMPACT OF COVID-19 SOCIAL DISTANCING MEASURES ON LIVELIHOODS, HEALTH AND LIFESTYLES STUDY (CIS) IN SUB-SAHARAN AFRICA AND AUSTRALIA
REFNo: SS526ES

The study aims to generate knowledge on the impact of COVID-19 social distancing measures on livelihoods, food security, health, family conflict and lifestyle changes. The study has three main objectives: 1. To describe the extent of application of social distancing measures in select countries. 2. To assess the choice of social distancing measures in select countries and the impact on the different outcome measures – livelihoods, food security, health, family conflict and lifestyle changes. 3. To identify areas most affected by choice of social distancing measures and make recommendations for future recurrent COVID-19 waves or similar pandemics.
Uganda 2020-11-30 2023-11-30 Social Science and Humanities Non-degree Award
Noble Banadda
ID:
FOOD and Local, Agricultural, and Nutritional Diversity
REFNo: A95ES

To develop, implement, and validate innovative, scalable, and sustainable technologies aimed at supporting the nutrition performance of local food systems in Africa, while strengthening agro-biodiversity and food diversity as well as diversity of healthy diets
Uganda 2020-11-30 2023-11-30 Agricultural Sciences Non-degree Award
CHARLES BENSTONS IBINGIRA RUKAMBURA
ID: UNCST-2021-R008521
Determination and characterisation of viral load and antibody profiles in samples from multiple sites of COVID-19 patients in Uganda
REFNo: HS1035ES

4 Study Objectives
This study will aim to determine viral load and antibody production / levels in diverse samples from COVID-19 patients.
Specific aims:
1. Determine and compare virus levels in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
2. Determine and compare antibody levels (IgM, IgG & IgA) in blood, saliva, naso/oro-pharyngeal swabs, urine, and stool of COVID-19 patients.
3. Determine and assess neutralising antibody (IgG & IgA) activity (in plasma, naso-phargygeal, saliva samples respectively) from COVID-19 patients.

Uganda 2020-11-30 2023-11-30 Medical and Health Sciences Non-degree Award
Atukunda  Gilbert
ID: UNCST-2020-R014643
Analysis of Workplace Practices of Educational Leadership and Management Graduates of Aga Khan University-IED, EA in Uganda.
REFNo: SS559ES

The objective of the study is to examine how Educational Leadership and Management graduates of Aga Khan University-IED, EA have transformed their workplace practices using the knowledge and skills obtained from the course.
Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
An Evaluation of the Pediatric Discharge Process following Hospital Admission with Sepsis/Severe Infection in Uganda
REFNo: HS928ES

The primary objective of this study is to evaluate the typical pediatric discharge process at a representative sample of hospitals in Uganda. The study will be guided by the following specific objectives.
Specially we intend to:
1. To assess the readiness of health facilities in providing minimum standard discharge care.
2. To assess health workers practices in the discharge care processes
3. To determine health worker perceptions of the quality of discharge processes.
4. To explore patient caregiver perceptions of the quality of discharge care experienced while their child was treated at the health facility.

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Anthony  Batte
ID: UNCST-2022-R011127
Prevalence of hypertension, HIV and Hepatitis B among participants of the world kidney day 2020 health screening in western Uganda (HHH Study)
REFNo: HS978ES

1. To describe the prevalence of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda
2. To evaluate the predictors of hypertension, HIV and hepatitis B among participants of the world kidney day 2020 health screening in western Uganda

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Emmanuel Kaggwa Henry
ID:
PEDAGOGICAL LEADERSHIP APPROACHES, LEARNING ENVIRONMENT AND ACADEMIC PERFORMANCE OF STUDENTS IN SECONDARY SCHOOLS: A CASE STUDY OF NAKASEKE DISTRICT-UGANDA
REFNo: SS627ES

1. To assess the state of academic performance of students in the secondary schools of Nakaseke district.
2. To establish the correlation between pedagogical leadership approaches and academic performance of students in Nakaseke district.

3. To examine the influence of learning environment on academic performance of students in Nakaseke district.

4. To establish a new, effective and practical pedagogical leadership approach that will enhance academic performance of students in Nakaseke district.
Uganda 2020-11-27 2023-11-27 Social Science and Humanities Degree Award
William Buwembo
ID: UNCST-2022-R009661
Anti-COVID-19 immunoglobulins G and M in blood specimens collected before lockdown at two urban clinics of Kampala, Uganda
REFNo: HS995ES

1. To determine the COVID-19 specific sero-prevalence at two urban clinics of Kampala, Uganda.
2. To determine the quality of virus specific antibody IgG in seropositive specimens
Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
Feasibility and Effectiveness of the National Research Information Management Systems (NRIMS) in Uganda; a Nested study within the Scaling up of capacity of Research Ethics Committees in Uganda (SCRECU).
REFNo: HS1052ES

Main Objective. To assess the feasibility and effectiveness of the National Research Information Management System (NRIMS) for effective Research Ethics Committee (REC) review process, facilitate multiple REC review, national registration and subsequent monitoring of approvals in Uganda. Specific. To assess the feasibility and effectiveness of NRIMS for review, registration and monitoring of research in Uganda. 2. To evaluate the cost economics of implementation of NRIMS.
Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Joseph Ochieng
ID:
Ethical and social issues for COVID-19 vaccine access in Uganda
REFNo: HS1101ES

The goal of the proposed study is to assess stakeholders’ awareness of ethical and social issues as well as perceptions of priority setting for COVID-19 vaccine accessto stimulate debate in preparation for COVID-19 vaccine and development of a model approach to priority setting in a Ugandan setting.

Aim 1. Assess stakeholders’ awareness of ethical considerations and social issues associated with COVID-19 vaccine access in Uganda
Aim 2. Assess stakeholders’ perceptions on ethical and social issues associated with priority setting for COVID-19 vaccine access in Uganda
Aim 3. Evaluate existing policies and guidelines on priority setting for COVID-19 vaccine access in Uganda
Aim 4. Develop a model approach to priority setting for COVID-19 vaccine access in Uganda

Uganda 2020-11-27 2023-11-27 Medical and Health Sciences Non-degree Award
Grace Brown
ID:
Sustainable Coffee Farming: Agricultural Growth, Cultural Shift, and Its Direct Effect on Decreased Gorilla/Human Disease Transmission
REFNo: NS87ES

To record the influence of local agricultural shifts on the health of gorilla group populations within Bwindi.
-Record diseases and illnesses through fecal sample that are linked to some sort of human interaction, whether it be direct or through livestock.
-Determine how coffee farmers perspectives on gorilla conservation have changed, if at all, with their participation in Gorilla Conservation Coffee.
-Study how farmers with steadier incomes can better support sustainability and conservation efforts within Bwindi Impenetrable National Forest.

USA 2020-11-26 2023-11-26 Natural Sciences Non-degree Award
Claire Akwongo Julie
ID:
Prevalence, Risk factors of exposure and Socio-Economic impact of Peste des Petits Ruminants (PPR) in Karenga District, Karamoja Region, Uganda
REFNo: A71ES

1. Determine the sero-prevalence of anti-SRM in goats and sheep in Karenga District using the Competitive Enzyme-linked Immunosorbent assay. 2. Determine the socio-economic impact of PPR amongst communities in Karenga using participatory epidemiology. 3. Establish the risk factors associated with the occurrence and spread of PPR in Karenga District using participatory epidemiology.
Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Chris Opesen C
ID:
EXPLORING THE PHILANTHROPY PRACTICE IN UGANDA
REFNo: SS471ES

The overall objective of this study is to explore the landscape for and of philanthropy in Uganda. The study has the following specific objectives:

I.To conduct a legal and policy analysis for philanthropy in Uganda including tax laws. Expected outputs
II.To identify local philanthropic initiatives in the five (5) districts of Kampala, Mbarara, Gulu, Arua and Masaka.
III.To establish the factors that enhance and hinder local philanthropy.
IV.Lastly, to develop recommendations for strengthening philanthropic practice in Uganda, as well as emerging research areas.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
Promoting hand hygiene through use of locally-produced alcohol based handrub in health facilities in Wakiso District-Uganda
REFNo: HS817ES

i) To develop a behavioral intervention to foster hand hygiene compliance using locally produced alcohol handrub in HCFs in Uganda.
ii) To assess the acceptability, feasibility and effect of locally-produced alcohol handrub on HH compliance among health care workers in primary health care facilities, Uganda.
(ii) To assess the cost of fostering HH through use of locally-produced
alcohol-based hand-rub.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
PAUL MBAGO
ID:
Bovine mastitis on selected farms in Kamwenge District: Prevalence and antibiograms of the associated bacteria
REFNo: A86ES

To determine the prevalence of bovine mastitis, antibiograms of associated bacteria and investigate presence of MecA and TetM resistance genes on selected farms in Kamwenge District.
Uganda 2020-11-26 2023-11-26 Agricultural Sciences Degree Award
Agabirwe Patience
ID:
INFORMATION PRACTICES OF STUDENTS WITH VISUAL IMPAIRMENT IN PUBLIC UNIVERSITY LIBRARIES IN UGANDA USING DIGITAL INFORMATION RESOURCES
REFNo: SIR49ES

To explore the information practices of students with visual impairment (SWVI) as they seek, access and use Digital information resources (DIRs) in public University libraries and therefore propose strategies to improve the utilization of DIRs by SWVI in University libraries of Uganda.
Uganda 2020-11-26 2023-11-26 Engineering and Technology Degree Award
Lina Sara Mathew Alonga Sara Mathew
ID:
Safety Profiling of Traditional Antimalaria Plant, Aristolochia bracteolata Lam. Commonly used among Communities of Jubek State, South Sudan
REFNo: HS851ES

i. To document the preparation methods, uses and effects of A. bracteolata antimalarial plant among the communities in Jubek State,
ii. To identify and quantify the levels of aristolochic acid in A. bracteolata and in preparation as used by the communities in South Sudan,
iii. To determine the general toxicity and nephrotoxicity of A. bracteolata community preparation using Laboratory animal models

South Sudan 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
owino ambrose
ID:
“Exploration of mathematics teachers’ pedagogical content knowledge for teaching subtraction strategy: A case study in Kwania District, Uganda”
REFNo: SS554ES

The purpose of this study is to explore mathematics teachers’ pedagogical content knowledge for teaching subtraction strategies.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Richard Mugambe Kibirango
ID:
The impact of an mhealth and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area. A cluster randomised trial.
REFNo: HS882ES

1. To explore the opportunities for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
2. To explore the barriers for enhancing healthcare workers’ hand hygiene practices in HCFs in the GKMA.
3. To compare the impact of mobile phone WASH text messages with that of environmental cues on hand hygiene practice among health workers in HCFs in the GKMA.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Emma Ariyo S
ID:
Examination of Sociocultural Boundaries and Gender construction in Women’s Rugby in Uganda
REFNo: SS579ES

1. Contributing to the body of literature on women rugby players’ use of sport to navigate socio-cultural structures in society.

2. Providing an in-depth understanding of how female participation in sport impacts multiple identities [relations] and relationships [social positioning] in reference to young women and their families and communities.

3. Inform educators, activists, policy makers and sport administrators’ decisions about developing sport opportunities for women in Uganda.
Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Edith Akankwasa
ID:
Implementing a child disability prevention, detection and rehabilitation project in central Uganda: Learning and experiences from the field
REFNo: HS896ES

i. To establish if amongst the intervention districts, those districts that show stronger implementation of birth defect and child disability prevention, child disability detection, management and rehabilitation interventions as envisaged perform better on key birth defect detection and child disability rehabilitation indicators compared to those intervention districts with “a lower level of implementation” (i.e., evidence of “dose-response”).
ii. To determine if, after three years, districts in project overall intervention area will show more improvement in coverage from baseline on key birth defect and child disability prevention, disability detection, management and rehabilitation indicators compared with those districts in the comparison area.
iii. To appraise the processes used in enhancing the delivery of the birth defect and child disability prevention, detection and rehabilitation services where they are being implemented.
iv. To explain in detail how and why the strategies employed led to the observed coverage in access to and utilization of the CDR project services in the implementation districts.
v. To characterize the stakeholders for birth defect and child disability prevention, detection and rehabilitation services.
vi. To document the barriers and facilitators used in the implementation of the CDR project along with how the barriers can be addressed

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
WINTERS MUTTAMBA
ID:
Exacerbation of Chronic Bronchial Sepsis (ECBS): A study of the role of key bacteria in exacerbations of COPD and bronchiectasis
REFNo: HS921ES

SECONDARY OBJECTIVES
i. To compare bacterial loads at presentation with time to first exacerbation.
ii. To assess the relationship of bacterial loads of specific bacteria with emergency attendance.
iii. To compare bacterial loads at presentation with time-to-clinical-stability (TCS), CRP response and length of antibiotics.
iv. To assess the relationship of specific bacterial loads with quality of life (QoL) scores.
v. To assess the microbiome dynamics during- and after- treatment.

EXPLORATORY OBJECTIVES
1. To compare bacterial loads with Bronchiectasis Severity Index (BSI) in those with a clinical diagnosis of bronchiectasis.
2. To compare admission bacterial loads with baseline FEV for relationship with key clinical outcomes.
3. To compare key clinical outcomes based upon initial counts of neutrophils, lymphocytes, platelets and eosinophils, and their ratios (including principally neutrophil-lymphocyte ratio, NLR, and platelet-lymphocyte ratio, PLR).
4. To compare bacterial loads with bronchiectasis severity index (BSI) in those with a clinical diagnosis of bronchiectasis.


Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
Reducing Tobacco use among the In- and Out-of-School youths in Moroto district, Uganda
REFNo: HS1021ES

General objective:
The general objective is to assess tobacco use among the youth in Moroto district.

Specific objectives:
1)Explore perceptions of tobacco use among youth in and out of school in Moroto district

2)Determine the factors associated with tobacco use among youth in and out of school in Moroto district

3)Describe the perceptions regarding tobacco use among the school teachers and administrators

4)Explore the cultural role that tobacco use plays in the lives of the youth in Moroto district.

5)Assess adherence to the tobacco control Act within bars and restaurants in Moroto district.

6)Assess youth access to tobacco in Moroto district.

7)Describe the perception of the implementation of tobacco control activities in Moroto district by enforcement officers.

Uganda 2020-11-26 2023-11-26 Medical and Health Sciences Non-degree Award
Shaheen Memon Mohamed Zahiruddin
ID:
APPLICATION OF MACHINE LEARNING TECHNIQUES TO ANTENATAL ATTENDANCE, MATERNAL MORBIDITY AND FETAL OUTCOMES IN UGANDA
REFNo: HS977ES

1. Establish the factors associated with the number of ANC visits by a pregnant woman who experiences SMM in Uganda.
2. Examine the factors associated with severe maternal morbidity as experienced by pregnant women in Uganda.
3. Assess the maternal factors associated with negative fetal outcomes in Uganda.

Kenya 2020-11-26 2023-11-26 Medical and Health Sciences Degree Award
Harriet Opondo
ID: UNCST-2022-R010927
Counselors’ Experiences of HIV Status Disclosure to Children living with HIV in Uganda
REFNo: SS626ES

-To explore subjective experiences of counselors during the process of status disclosure to children living with HIV
-To find out how counselors are prepared and trained to conduct status disclosure to children living with HIV.
-To establish the current interventions used by counselors in HIV disclosure process to children.
-To find out self-identified training needs of counselors during and after status disclosure to children living with HIV.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
REFNo: SS632ES

Suubi4Stigma will address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV/AIDS-associated stigma and its negative impact on child health and psychosocial well-being. Specifically, the proposed study will examine two evidence-based interventions used in mental health settings, schools, and communities: 1) group cognitive behavior therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level; and 2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH and their families.

Aim 1: Pilot test the feasibility, acceptability, and preliminary impact of innovative G-CBT and MFG on reducing HIV/AIDS-associated (internalized and family-level) stigma and its’ impact on youth and family-level outcomes (stigma, trauma symptoms, depression, sexual risk, family/social support and adherence to medication) compared to: 1a) usual care vs G-CBT; b) Usual care vs MFG; c) G-CBT vs. MFG;

Aim 2: Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to G-CBT and MFG intervention implementation and participation.

Uganda 2020-11-26 2023-11-26 Social Science and Humanities Non-degree Award
Joseph Oloro
ID: UNCST-2024-R004525
Toxicological study of the antimalarial remedy (Artavol®) and its flavonoid isolate from artemesia annua
REFNo: HS540ES

To determine acute toxicity of Artavol® and of its isolated flavonoids
ii. To investigate the sub-acute and sub-chronic toxicity potential of Artavol® and of its isolated flavonoids.
iii. To evaluate the effects of Artavol® and of its isolated flavonoids on the fetus.
iv. To examine the mutagenic potential of Artavol® and of its isolated flavonoids.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Characteristics of persons screened, tested and diagnosed with corona virus disease-19 at health facilities in Uganda
REFNo: HS657ES

Main objective:
To estimate the cumulative incidence of a composite treatment outcome of admission to intensive care unit, mechanical ventilation or death among COVID-19 confirmed patients attending health facilities in Uganda for COVID-19 care.

Secondary objectives:
1. To describe the socio-demographic, behavioral and clinical characteristics of patients screened for and or receiving COVID-19 care at health facilities in Uganda
2. To determine the screening and testing outcomes of COVID-19 infections among patients at health facilities in Uganda

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
DECENTRALIZATION OF BENZATHINE PENICILLIN G BEST PRACTICES: BUILDING THE TOOLS FOR A SUSTAINABLE AND SCALABLE PROGRAM
REFNo: HS835ES

(1) Develop materials that can be used across Uganda and East Africa to strengthen BPG administration skills in the health worker community,
(2) Test this package of materials in Lira and Mbarara, areas with high BPG demands, and
(3) Evaluate the immediate and 3-month results of the educational program on proper BPG delivery, health worker comfort, and patient satisfaction.

Uganda 2020-11-25 2023-11-25 Medical and Health Sciences Degree Award
Firminus  Mugumya
ID:
Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES

The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?

The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?

Uganda 2020-11-25 2023-11-25 Social Science and Humanities Non-degree Award
Ronald Mulondo Mulondo
ID:
Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES

1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Benjamin Atwine
ID:
Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES

General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES

To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES

1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Viola Karungi
ID:
Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES

The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?


Uganda 2020-11-23 2023-11-23 Social Science and Humanities Degree Award
Stella Neema
ID: UNCST-2019-R000814
Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES

The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.

Uganda 2020-11-23 2023-11-23 Social Science and Humanities Non-degree Award
DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES

a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
Uganda 2020-11-23 2023-11-23 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
Barbara Mukasa
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES

(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS

Uganda 2020-11-20 2023-11-20 Social Science and Humanities Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES

-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas

Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
Predictors of indoor air quality in Kisenyi-Mugunu a slum settlement in Fort Portal Municipality, Uganda
REFNo: HS695ES

General objective
To assess predictors of indoor air quality so as to promote the health of children under five dwelling in Kisenyi-Mugunu, Fort Portal Municipality.
Specific objectives
1. To determine the level of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
2. To establish the predictors of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
3. To explore the barriers and facilitators to uptake of healthier household energy options in Kisenyi-Mugunu.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
Characterizing Determinants of Primary KSHV Infection among Children and Adolescents in Uganda
REFNo: HS735ES

1. To determine the incidence and to define the viral, immunologic, and clinical features of primary KSHV infection.
2. To identify the biologic and behavioral risk factors associated with primary KSHV infection.
3. To develop mathematical models that characterize KSHV shedding dynamics and virologic drivers required for transmission.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
Machine Learning and Secondary Data Analyses of the RASHOTS Database to Guide Clinical Decision Making and Predict Patient Prognosis at Kiruddu National Referral Hospital, Uganda
REFNo: HS745ES

The primary project objectives are:
1. To utilise ML methods to estimate the risk of mortality on the ID wards at Kiruddu National Referral Hospitals using the RASHOTS medical database
2. To develop prognosis prediction scores for survival on the ID wards using ML methods on the RASHOTS medical database based on clinical prognostic factors

The secondary project objectives are:
1. To estimate the prevalence of major mortality drivers such as tuberculosis, tetanus using the RASHOTS medical database
2. To create a prognosis prediction protocol for risk of tuberculosis related mortality as a computer application for use by clinicians on ID wards
3. To use the RASHOTS database for quality improvement in clinical care and practice in the department of Internal Medicine

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Annette Namugaya Mugabe Jane
ID: UNCST-2020-R014795
TRENDS AND INDICATIONS FOR CAESAREAN SECTION IN MBALE REGIONAL REFERRAL HOSPITAL A CROSS SECTIONAL STUDY
REFNo: HS777ES

General Objective
To determine the trends and indications for caesarean section delivery in MRRH (Eastern Uganda) during the study period (July 2013 to June 2018)

Specific Objectives
1. To determine the trend for caesarean section in MRRH (Eastern Uganda) over the study period
2. To identify the indications for CS delivery in MRRH (Eastern Uganda) over the study period

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
Next Generation Nutrition in Uganda: Enhancing Dietary Intake of Iron and Folic Acid in a Culturally Acceptable Food Product for Pregnant Women to Improve Maternal and Child Outcomes
REFNo: HS828ES

Evaluate the effect of the innovative product on the health outcomes of the infants at birth,Investigate the efficacy of this innovative product to reduce iron and folic acid deficiency in pregnant women.,Develop a culturally acceptable and quality assured iron bio-fortified beans and silverfish pre-cooked instant sauce fortified with iron and folic acid to meet nutritional needs for pregnancy.,
Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
“Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Jonathan Nsamba
ID: UNCST-2024-R003888
Body composition and muscular health of children and adolescents diagnosed with type 1 diabetes mellitus in Uganda
REFNo: HS759ES

1. To determine the body composition of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
2. To determine the hand grip strength of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
3. To examine the associations between dietary intake patterns, physical activity, nutrition status and body composition among children and adolescents diagnosed with T1DM
4. To understand the perceptions of newly diagnosed Type 1 Diabetes Mellitus children and adolescents about their disease status, barriers and facilitators to self-care.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
FADHIL GERIGA
ID: UNCST-2022-R011524
Optimizing Nephroblastoma treatment outcomes in Uganda
REFNo: HS822ES

Primary Objectives:
o To determine the one-year survival of children with pathology confirmed nephroblastoma treated with multidisciplinary, stage-based care in Uganda.
o Assess the factors associated with morbidity and mortality among children with nephroblastoma.

Secondary Objectives:
o Characterize the frequency and spectrum of other malignancies that present similar to Nephroblastoma
o Characterize the social needs and health literacy of nephroblastoma patients and their caregivers at the UCI
o Assess quality measures of a multidisciplinary care, including:
- Treatment timing benchmarks following guidelines developed for UCI
- Adherence to treatment plan and elimination of loss to follow-up
o Assess social needs and provide a patient navigator for families of children with nephroblastoma and reduce the non-clinical barriers to care for children with nephroblastoma

Exploratory Objectives:
o To collect plasma for future studies evaluating circulating tumor DNA as a tool for diagnosis of pediatric kidney cancers and monitoring of patients with nephroblastoma.
o Collect stool specimens for future studies to define baseline factors in the stool microbiome that are associated with neutropenic fevers, sepsis and 12 months survival using combination of sequencing methods and stool ova and parasites evaluation.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
EXPLORING CHILDREN’S UNDERSTANDING OF COVID-19 AND ITS PREVENTIVE STRATEGIES IN UGANDA: A CROSS SECTIONAL STUDY AMONG CHILDREN AGED 10-13 YEARS IN HOIMA DISTRICT
REFNo: HS830ES

General objective

To explore children’s understanding of COVID-19 disease and related preventive measures, in order to generate information that will guide the development of evidence-based strategies for strengthening and improving children safety and wellbeing during and after the COVID-19 crisis.

Specific objectives

1.To establish the children’s knowledge of COVID-19 transmission and its preventative measures in Hoima Municipal Council

2.To describe how the COVID-19 preventative measures are understood and practiced by children aged 10 to 13 years in Hoima Municipal Council

3.To explore the enablers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

4.To explore the barriers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Formative Study to Understand Drivers and Barriers to Uptake of Permanent Methods of Family Planning Among Men and Women in Busoga Sub region
REFNo: HS862ES

The overall objective is to understand the factors that influence women, men and providers in Busoga region during the journey to access PMs to enable PSIU to design interventions.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
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