Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
George Kasule
ID: UNCST-2025-R020040
HOUSEHOLD DEBT MANAGEMENT IN UGANDA
REFNo: SS4141ES

1. To investigate the relationship between number of the loan and household debt management in Uganda.
2. To examine the moderating effect of purpose of the loan in the relationship between number of loans and household debt management in Uganda.
3. To assess the relationship between financial knowledge and household debt management in Uganda.
4. To investigate the relationship between institutional innovative financial technologies and household debt management in Uganda.
5. To assess the relationship between social networks and household debt management in Uganda
6. To examine the relationship between remittances and household debt management in Uganda.

Uganda 2025-09-03 5:06:34 2028-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
CASCADE C-3001-A: Comparison of Clinic-based versus Clinic- plus Community Outreach-based Strategy to Increase Uptake of Cervical Cancer Screening via HPV Self-Collection among Women Living with HIV: a Cluster Randomized Trial.
REFNo: HS6333ES

To compare cervical cancer monthly screening rates in screen-eligible women living with HIV (WLWH) between the two screening models: standard-of-care for cervical cancer screening through static clinics only (Model 1) versus HPV self-collection through both static clinics and a community-based screening strategy by facility link facilitators (FLFs) (Model 2). Standard-of-care for Model 1 is defined as HPV self-collection when available or Visual Inspection with Acetic Acid (VIA) when HPV-based screening is not available
Uganda 2025-09-03 5:05:44 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel  Emoru Reagan
ID: UNCST-2025-R020048
Safeguarding Public Health in the Face of Climate Change: Evaluating Uganda's National Policies and Catalyzing Stakeholder Action
REFNo: HS6332ES

1. To conduct a comprehensive review and analysis of Uganda’s national climate change policies, with a particular emphasis on understanding what policies are available and identifying and assessing the inclusion of health-related impacts, risks, and adaptation/mitigation measures.
2. To evaluate the mechanisms and efforts undertaken by the government and development partners to disseminate and raise awareness about these national climate change policies among relevant stakeholders.
3. To identify gaps and provide recommendations for strengthening the integration of health considerations in national climate change policies, as well as improving the dissemination and awareness-raising efforts among key stakeholders.

Uganda 2025-09-03 5:03:32 2028-09-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Cardiovascular risk factor profiles and outcomes in rural Uganda: The Bugoye Hypertension Improvement Project (B-HIP)
REFNo: HS6350ES

To evaluate the dietary intake and nutritional habits of adult patients visiting the BHIP clinic. To determine incidence of sustained blood pressure control among persons with hypertension enrolled in BHIP. To assess the costs of hypertension care in a Level III healthcare center in rural Uganda. ,1. To assess the baseline (at time of enrollment to BHIP) prevalence of various cardiovascular risk factors (obesity, dyslipidemia, and diabetes mellitus) in adults visiting the Bugoye Hypertension Improvement Project.,
Uganda 2025-09-03 4:49:54 2028-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Slyvia  Aarakit Manjeri
ID: UNCST-2025-R016896
GREEN ENERGY FOR WOMEN AND YOUTH RESILIENCE IN UGANDA: BRIDGING THE SKILLS GAP THROUGH TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING-TVET
REFNo: SS4196ES

Objectives
Theme 1: Mapping and Readiness
(i) To map Uganda’s clean energy sub-sector to identify knowledge, technical, and business skill gaps among women and youth entrepreneurs.
(ii) To assess the institutional readiness and capacity of TVETs to deliver inclusive, industry-relevant green energy and clean cooking training.
Theme 2: Curriculum and training
(iii) To co-create a green energy and clean cooking training curriculum for TVET institutions, and strengthen their technical capacity to deliver hands-on, industry-relevant training.
(iv) To enhance the technical and entrepreneurial skills of women and youth to produce/innovate and distribute green and clean cooking solutions in their communities.
Theme 3: Scale-up and Policy Influence
(v) To assess the contribution of TVET-based green energy and clean cooking training programs to green skills development, inclusive participation and resilience of women and youth entrepreneurs.
(vi) To promote public awareness and policy advocacy through transdisciplinarity in knowledge co-creation and dissemination among academia, TVET institutions, communities, policymakers, and private sector actors.

Uganda 2025-09-03 4:47:32 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Wellness4Students Program to Mitigate Stress, Anxiety, and Depression among Makerere University Students in Uganda (Wellness4Students Project)
REFNo: SS4200ES

1.3 Aim and objectives of the study
This study aims to co-create, implement, and evaluate the feasibility and acceptability of a Wellness4Students supportive email/WhatsApp messaging program to mitigate symptoms of stress, anxiety, and depression and to promote well-being among university students in Uganda.

Specific Aims
Aim 1: To co-create and adapt the Wellness4Students intervention for SAD and mental well-being for university students in Uganda. We will co-create the Wellness4Students (W4S) program and then adapt it for students at Makerere University [27, 28, 36].
Aim 2: To determine the prevalence of stress, anxiety, and depression among university students in Uganda. We will use a self-administered online baseline survey to measure these outcomes. The primary outcomes will be Stress, Anxiety, and Depression (SAD) and well-being. This will be measured using the Psychological Stress Scale (PSS-10), Generalized Anxiety Disorder (GAD-7), the Patient Health Questionnaire (PHQ-9), and the WHO Wellbeing Scale [14, 37-40]. We will estimate the prevalence of each of these outcomes separately. to assess the impact of the program on stress, anxiety and depression?
Aim 3:. To assess the feasibility and acceptability of the Wellness4Students intervention for addressing stress, anxiety, and depression among university students in Uganda, as well as to evaluate its impact.
We will assess the daily consistency in program participation (i.e. ability to read daily messages), completion rates (Lost to follow-up), the improvement in mean scores of Stress, Anxiety, and Depression at 3 months, and 6 months [14, 27, 37-40]. End-line survey perceptions and feedback about the program at 6 months will be evaluated. At the end of the intervention and follow up survey, we will conduct a satisfaction survey, as indicated in the last section of the survey questionnaire.

Aim 4: To investigate the association between demographic factors and Stress, Anxiety, and Depression among University students in Uganda.

Uganda 2025-09-03 4:46:07 2028-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hellen Opolot
ID: UNCST-2019-R001724
An Evaluation of Compliance to Uganda National Research Regulations
REFNo: SS4169ES

Overall objective:

To investigate extent and the drivers of compliance with national research regulations/guidelines among regulators, institutional committees and researchers in Uganda.

Specific objectives

1. To establish the extent of compliance to the national research ethics guidelines/regulations by research regulators, ethics committees and researchers in Uganda
2. To assess the factors associated with Compliance to national research ethics guidelines/regulations by researchers, Institutional Committees and research regulators in Uganda
3. To explore barriers and facilitators of regulatory inspections, audits and enforcement of national research ethics regulations/guidelines by regulators and ethics committees in Uganda
4. To explore barriers and facilitators of compliance to the national research ethics regulations /guidelines by researchers in Uganda

Uganda 2025-09-02 12:03:37 2028-09-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
Dual Generation Interventions and Poverty Alleviation in Refugee Settlements in Uganda
REFNo: SS4265ES

The primary research objective for the proposed study is to determine if households participating in both the ultra-poor graduation program (UPG) and Humanitarian Play Lab (HPL) will have better outcomes for households, caregivers and children than households participating in the humanitarian play lab alone.
Specifically, the study seeks to:
(i) Examine if households which participate in both the Ultra-poor graduation and Humanitarian Play Lab programs have more income and are more food secure than households which only participate in the Humanitarian Play Lab program
(ii) Ascertain if Caregivers of households which participate in both the Humanitarian Play Lab program and the Humanitarian Play Lab program and those which only participate in HPL are different regarding time use, mindset and aspirations, knowledge and practices related to child development, gender attitudes and dynamics, mental health, well-being, stress, and post-traumatic stress disorder.
(iii) Analyse if children in households which participate in both the Humanitarian Play Lab program and the Humanitarian Play Lab program program have higher development outcomes than children of households that only participate in the Humanitarian Play Lab program

Uganda 2025-09-02 10:11:25 2028-09-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred  Bulamba
ID: UNCST-2020-R014888
PErioperative respiratory care and outcomes for patieNts Undergoing hIgh risk abdomiNal surgery
REFNo: HS2178ES

To explore the cost-effectiveness of the different treatment combinations in reducing pneumonia and SSI at pre-selected centres.,To assess the impact of both interventions on postoperative mortality at 30-days, and the effect of 80-100% FiO2 only on the re-operation rate at 30 days after surgery.,To assess whether (1) preoperative 0.2% chlorhexidine mouthwash reduces the rate of postoperative pneumonia at 30-days compared to no mouthwash, and (2) 80-100% FiO2 used during surgery reduces the rate of postoperative SSI at 30-days compared to 21-35% FiO2, amongst patients aged 10 years or over undergoing elective or emergency midline laparotomy, with an anticipated abdominal incision of ≥5cm, for any indication except caesarean section.,
Uganda 2025-08-28 10:15:49 2028-08-28 Medical and Health Sciences Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Neuropsychiatric Genetics of African Populations - Psychosis, II NeuroGAP-Psychosis II
REFNo: HS6452ES

i). Expand knowledge of the genetic architecture of schizophrenia and bipolar disorder in the African continent
through large-scale sample collection and analysis in Uganda
ii) Increase understanding of the genetics of African populations, through various methods for biospecimen
collection
iii) Enhance neuropsychiatric genetic research capacity in Africa through the training of scientists and supporting
the development of locally-led research programs
Uganda 2025-08-27 14:38:09 2028-08-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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