Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Daniel Magumba
ID: UNCST-2025-R018334
 PEDESTRIAN ROAD SAFETY IN KAMPALA: A MIXED METHODS STUDY OF THE WALKABILITY OF KAMPALA’S ROAD INFRASTRUCTURE
REFNo: HS6064ES

1.To assess the Walkability of Kampala City’s Road infrastructure.
2.To explore stakeholder perceptions on pedestrian safety and walkability of Kampala city.

 Uganda 2025-06-26 23:54:31 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charlot Diepvens
ID: UNCST-2025-R017733
 Demand-side enablers and barriers to epidemic preparedness: a mixed-method approach to understand priorities, acceptance and effective strategies for Ebola vaccines
REFNo: HS6132ES

The objective of this study is to examine demand-side factors that influence (enable or hinder) epidemic preparedness, with a focus on licensed Ebola vaccines. Specifically, it aims to visually identify and map key influencing factors, and to adequately translate their effects into quantitative models. This translation is critical, as decision-makers frequently rely on models—such as disease transmission models—to guide outbreak response strategies. Modeling has the potential to demonstrate the impact of specific interventions (e.g., additional training, improved guidelines, or the provision of dedicated funding) on vaccine use. This case study explores priorities and acceptance regarding licensed Ebola vaccines among decision makers. It also examines how these perceptions shift under different vaccination strategies, including reactive vaccination (during an outbreak) versus preventive vaccination (outside of an outbreak). More specifically, the studies objectives are to: 1. Identify and map key influences or determinants of vaccine use in Uganda through a conceptual systems diagram (e.g., perceptions of personal risk, fear of vaccine side effects), building on key informant interviews and group model building workshops. 2. Develop and validate a quantitative simulation model evaluating the impact of various vaccination strategies and interventions on vaccine use over time. 3. Derive insights from the diagram and model to inform policy and strategic decision-making at local and national levels regarding Ebola vaccine implementation. In short, the study will develop a visual representation of the problem space that can guide both policy and practice.
 Belgium 2025-06-26 23:52:36 2028-06-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Socio-Cultural and Anthropological Perspectives on Child Feeding and Care, Food Consumption Habits, Dietary Patterns and Purchasing Behaviours in Uganda
REFNo: HS5843ES

Examine similarities and differences in caregiving practices that affect children’s nutrition across high-producing agricultural areas, pastoral regions, and urban landscapes,Explore the current perception of social behaviour change communication on complementary feeding.,Assess household dietary and food consumption behaviour,Examine caregivers\' purchasing habits and children’s food preferences, considering economic and cultural factors.,To gather comprehensive anthropological data on the dietary habits of children under 2 and the purchasing behaviours of caregivers in the districts of Kamwenge, Napak, and the urban areas of Kampala,
 Uganda 2025-06-26 23:51:22 2028-06-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SEDRIC NABAASA NKUBA
ID: UNCST-2024-R016326
 Peer Influence, Alcohol Use and Risky Sexual Behaviors among Adolescent Students in Secondary Schools in Greater Mbarara
REFNo: SS3934ES

1. To explore the gender difference in prevalence of risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
2. To establish impacts of peer influence on risky sexual behaviors among adolescent students in secondary schools in greater Mbarara.
3. To determine the mediation effects of alcohol us on the relationship between peer influence and risk sexual behaviors among adolescent students in secondary schools in greater Mbarara.
4. To explore the perceptions of adolescent students in controlling risk sexual behaviors in secondary schools in greater Mbarara

 Uganda 2025-06-25 13:34:21 2028-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
 Understanding Post-Discharge Mortality in children living with HIV who are hospitalized (SUPPORT1-PDM)
REFNo: HS6005ES

1. To assess the impact of an improved follow-up on reducing PDM in CLHIV 2. To evaluate the performance of disease severity biomarkers in this specific population to predict PDM 3. To analyze changes in serial measurements of CMV and potential association with PDM at day +360 in CLHIV 4. To describe the number of children with persistent detection of a specific respiratory pathogen 5. To describe the number of children with persistent detection of specific gastrointestinal (GI) pathogens 6. To describe the number of cases of histoplasmosis in CLHIV, its clinical characteristics, and outcomes in the identified cases, up to +360 days after discharge 7. To describe the prevalence of MDR colonization at enrollment, the microorganism isolated, and the duration of the colonization 8. To describe the main characteristics of readmissions, deaths and morbidity during 1-year follow-up after enrollment
 Uganda 2025-06-25 13:30:24 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIAN APAKO
ID: UNCST-2024-R004399
 LUNAS as a versatile and simple technique for malaria testing in a high transmission, rural setting
REFNo: HS5918ES

Primary objective - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to common routine malaria testing (RDT and microscopy) during standard patient care in malaria-suspected individuals presenting at Kumi Hospital, Kumi, Uganda. Secondary objectives - To determine the diagnostic accuracy of LUNAS POCT for malaria compared to a commercial LAMP test - To determine the prevalence of malaria infections categorized by Plasmodium species. - To determine the correlation between time to positivity of both LAMP and LUNAS and parasitaemia as assessed by reference microscopy. - To determine the prevalence of P. falciparum harbouring deletions or mutations of the pfhrp2/3 gene in study participants, who have a P. falciparum infection with a parasitaemia as assessed by reference microscopy but a negative Pf HRP2/3 RDT result. - To determine the prevalence of Pf kelch13 (K13) gene mutations, which have been associated with resistance to artemisinin. - To determine the effectiveness of dried blood spots (DBS) for long term storage and transport of patient samples at ambient temperature for PCR testing.
Uganda 2025-06-25 13:26:35 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 MATERNAL INFANT BONDING AND BREAST-FEEDING OUTCOMES IN UGANDAN MOTHERS DIAGNOSED WITH POSTPARTUM DEPRESSION IN PUBLIC HEALTH FACILITIES IN MBARARA DISTRICT, SOUTH WESTERN UGANDA
REFNo: HS5848ES

1. To determine the prevalence of maternal bonding impairment among mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
2. To determine the breast-feeding outcomes of children born to mothers diagnosed with PPD in a public health facility in Mbarara district, South western Uganda.
3. To explore the lived bonding and breast-feeding experiences of mothers Diagnosed with PPD in a public health facility in Mbarara district, South western Uganda

 Uganda 2025-06-25 13:21:19 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve Wabule
ID: UNCST-2024-R004285
 DRIVERS OF NO-SHOWS FOR AMBULATORY APPENDECTOMY AMONG PATIENTS SCHEDULED FOR AMBULATORY APPENDECTOMY AT KYABIRWA SURGICAL CENTER
REFNo: HS6046ES

To establish the institutional drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the patient-related drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,To determine the prevalence of no-shows for ambulatory appendectomy among patients seeking ambulatory surgery at Kyabirwa surgical center,To assess the drivers of no-shows for ambulatory appendectomy among patients scheduled for ambulatory appendectomy at Kyabirwa surgical center,
 Uganda 2025-06-25 13:19:11 2028-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Atek kagirita
ID: UNCST-2024-R015689
 LABORATORY SYSTEM RESILIENCE TO CORONAVIRUS DISEASE-19 OUTBREAK; ITS PREDICTORS, POLICY, AND PRIVATE SECTOR SUPPORT IN UGANDA
REFNo: HS6101ES

General objective
To assess the level of laboratory system resilience to COVID-19 disease outbreak, its predictors, appropriateness of policies to support it, and capacity of private sector laboratories to impact it in Uganda
4.2.2 Specific objectives
1. To determine the level and characteristics of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
2. To establish the predictors of resilience among licensed / accredited COVID-19 testing laboratories in Uganda.
3. To describe private sector laboratory capacity to contribute to national laboratory system resilience during the COVID-19 pandemic outbreaks
4. To appraise the appropriateness of current/emerging policies to support laboratory resilience during the COVID-19 pandemic outbreaks
 Uganda 2025-06-23 13:30:18 2028-06-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 Development of context-appropriate approaches for the recruitment and retention of women of childbearing age and pregnant women in antimalarial clinical trials
REFNo: HS6036ES

1. To understand the context, socio-cultural practices and beliefs around early pregnancy as well as collecting experience with and/or perception of previous clinical trials to inform the development of culturally acceptable and understandable communication materials about the SAFIRE trial, including the information sheets for obtaining consent.
2. To identify factors and individuals that may influence WOCBA and pregnant women’s decision-making around participation and retention in the clinical trial to be addressed as part of project procedures and communications.
3. To explore approaches for facilitating the inclusion of WOCBA and pregnant women (in early pregnancy) in the clinical trial, based on the findings from objective 2.
4. To identify key stakeholders (including household decision-makers, community leaders and opinion shapers, health sector actors), from community to national levels, to be included and involved in the community engagement strategy prior to trial implementation.

 Uganda 2025-06-20 9:25:32 2028-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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