Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
 Uganda Gender and Tuberculosis Key Populations Assessment
REFNo: HS1864ES

1. To establish the gender differences evident in TB care cascade (diagnosis through treatment) records in Uganda. 2. To determine the gender barriers and facilitators to TB prevention, diagnosis, treatment and treatment completion in Uganda. 3. To generate information to guide the listing of TB KVPs relevant to Uganda context, and for designing interventions for addressing the gaps among prioritized KVPs. 4. To determine to what extent the National TB response (NSP and policies/guidelines) addresses gender and KVP issues in Uganda.
 Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Exposure-Response Evaluation of IV Artesunate in Children with Severe Malaria
REFNo: HS2027ES

Primary:
• To determine the relationship between dihydroartemisinin (DHA) exposures following intravenous dosing and markers of physiologic dysfunction associated with severe malaria
Secondary:
• To determine the relationship between DHA exposures and time to hospital discharge
• To determine the relationship between DHA exposures and parasite clearance associated with treatment of severe malaria.
Exploratory:
• To determine the relationship between DHA exposures and neurodevelopmental outcomes associated with treatment of severe malaria outcomes and explore predictors that may affect this relationship
• To evaluate the role of parasite clearance as a mediator of the relationship between DHA exposures and markers of physiologic dysfunction associated with severe malaria
• To develop a score comprised of markers of physiologic dysfunction and describe its relationship to clinical outcomes
• To assess P. falciparum infections for artemisinin resistance

Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
Danielle Falk
ID:
Educators in Emergencies: The Lived Experiences and Professional Identities of Refugee and National Primary School Teachers in Uganda and South Sudan
REFNo: SS1213ES

To determine in what ways teachers conceptualize their professional identities,To understand how protracted conflict, forced displacement, and recurrent migration influences teachers’ lived experiences in their classrooms, schools, and communities in refugee-producing and receiving countries,To explore the lived experiences and professional identities of refugee and National Primary School Teachers in Uganda and South Sudan,
 USA 2022-03-14 2025-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Wambuzi
ID:
Community Engagement Strengthening for future HIV Vaccice trial participation in fishing communities around Entebbe,Uganda( CEVAC)
REFNo: SS1201ES

1. To assess knowledge on HIV vaccine trials among people living in FCs around Entebbe, Uganda.
2. To assess willingness to participate in future HIV vaccine trials among people living in FCs around Entebbe, Uganda.
3. To understand HIV vaccine trials experiences and motivators to participation among former participants.
4. To explore communities’ experiences, perceptions and preferences for community engagement among FCs around Entebbe, Uganda.

 Uganda 2022-03-11 2025-03-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ambrose Oruni
ID:
Impact of escalating insecticide resistance on malaria control tools and parasite transmission in An. funestus from Uganda
REFNo: HS2063ES


i. Temporal monitoring of super-resistance every 6 months for 3 years. The frequency of the known resistance markers, changes in transcription profiles of resistance genes and variations in the genome will be monitored.

ii. Assess the impact of super-resistance on the effectiveness of the current and novel bednets against An. funestus.

iii. Assess the impact of super-resistance on malaria entomological transmission indices.

 Uganda 2022-03-11 2025-03-11 Medical and Health Sciences Non-Clinical Trial Degree Award
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