Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Catherine Mulinde
ID: UNCST-2023-R006953
Efficiency of adaptation to climate change induced vulnerability and household welfare in Coffee-Based Farming Systems of Uganda (EACCHS)
REFNo: A389ES

General Objective:
The overall goal of the research is to identify adaptation practices that are efficient at alleviating climate change effects and at enhancing crop productivity and household welfare in CBFS of Uganda.

Specific objectives:
a) Determine household vulnerability to climate shocks across the CBFS of Uganda.
b) Assess the variation in existing adaptation practices across different levels of household vulnerability to climate change effects among male and female coffee farmers of Uganda.
c) Evaluate the effect of climate adaptation practices on household welfare in CBFS of Uganda.
d) Assess the future efficiency of selected climate adaptation practices in sustaining crop yields in CBFS of Uganda by 2070.

Uganda 2024-10-23 17:40:16 2027-10-23 Agricultural Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Xpert Hepatitis B Viral Load Point-of-Care Molecular Test
REFNo: HS4687ES

3. Estimate the cost of utilizing GeneXpert machines for hepatitis B viral load testing in comparison to the centralized conventional hepatitis B testing conducted by CPHL.,2. To describe the operational characteristics and ease of use of the assays and their suitability for Uganda among laboratory technicians at selected health facilities in Uganda. ,1. To verify the diagnostic accuracy of the Cepheid Xpert HBV VL platform with the TaqMan HBV test Roche platforms at CPHL. ,The overall objective of the performance evaluation is to evaluate the performance and operational characteristics of Xpert® HBV Viral Load assay intended for the quantification of HBV viral load in HBV-infected individuals and verify that they meet the minimum requirements for adoption in Uganda. We will also assess the feasibility of integrating hepatitis B viral load testing into existing GeneXpert machines in Uganda. ,
Uganda 2024-10-23 17:38:07 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
Feasibility of a culturally tailored implementation strategy: WHO Lay Health Worker Dementia Care with Internal Facilitation from Health Assistants as supervisors
REFNo: HS5150ES

2. Evaluate the feasibility of an implementation strategy consisting of WHO Lay Health Worker Dementia Care with Internal Facilitation (WLDC+IF),1. Co-design an implementation strategy guide for the WHO Lay Health Worker Dementia Care, with Internal Facilitation (WLDC+IF) ,To develop and evaluate the feasibility of a culturally tailored implementation strategy consisting of the WHO dementia toolkit by indigenous village-based LHWs to provide dementia care at village level supported by internal facilitation (implementation support, process improvement and practice sustainment) from indigenous HAs as supervisors: the “WHO Lay Health Worker Dementia Care, with Internal Facilitation (WLDC+IF)”.,
Uganda 2024-10-23 17:37:07 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
Health Education on Heart Failure in Uganda: A study on effective interventions for early diagnosis and disease prevention
REFNo: HS4323ES

How can stronger levels of trust be developed between the Medly program and local communities; and what policies would be most effective for increasing clinical access in Uganda to improve the identification of people at risk of heart failure? ,To identify resources that could be utilized to promote heart health education for health workers and community members, support heart failure prevention efforts, and increase screening of people at risk in their local communities early on,Toidentify interventions (e.g., clinical, technological, community-led) would be most effective in improving the early diagnosis of cardiovascular disease and the prevention of heart failure in Uganda,To determine factors that contribute to CVD risk at the individual, family and community level ,The objective of this project is to generate new and actionable knowledge focused on strengthening the uptake of Medly Uganda by heart failure patients through a mixed-methods research approach among Ugandan communities,
Uganda 2024-10-23 17:35:52 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Nanfuka Kalule
ID:
MID-TERM (2022) AND FINAL/EX-POST (2023) EVALUATION OF THE GAME CONNECT PROGRAMME
REFNo: SS2703ES

To learn on an ongoing basis so as to improve the design and implementation of Game Connect, as well as other ongoing (and future) ORF-funded sport for protection programmes in Uganda and beyond.

To build the evidence base on specific areas of the intervention, and to increase knowledge and understanding of the outcomes and impacts for the participants.
Uganda 2024-10-23 17:34:41 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Elisa  Macchi
ID: UNCST-2023-R004097
Gains: Perceptions of Misaligned Incentives in Health:
REFNo: SS2729ES

To understand the correlation between BMI, and wealth/earnings.
Italy 2024-10-23 17:32:50 2027-10-23 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Agonzibwa
ID: UNCST-2024-R004214
Resource Mobilization Modalities And Their Influence On The Viability Of Academic Programs In Private Universities In Fort Portal City
REFNo: HS4561ES

3. Examine the efficiency of current resource allocation practices and their contribution to sustainability in Fort Portal City\'s Private Universities.,2. To investigate the effectiveness of partnerships and collaborations in mobilizing resources on the viability of academic programs in private universities in Fort Portal City.,1. Evaluate how private universities in Fort Portal City engage with various stakeholders to mobilize resources for the viability of their academic programs,The general objective of this study is to systematically investigate the effectiveness of existing financial resource mobilization approaches and their direct influence on the viability of academic programs in Uganda.,
Uganda 2024-10-23 17:31:44 2027-10-23 Social Science and Humanities Non-Clinical Trial Degree Award
Ouma Simple
ID: UNCST-2021-R012820
AJOLI: Developing culturally-sensitive understanding of autism and community needs in Uganda
REFNo: HS4564ES

1. Work with stakeholders in three representative districts in Northern Uganda (Gulu city, Amuru and Pader) to develop culturally sensitive understandings of autism and community needs using a qualitative methodology.
2. Use participatory methods, to develop accessible resources to explain about autism and address sociocultural misconceptions.
3. Map likely autism prevalence among communities using a brief, low-cost, culturally-sensitive autism screener across three sites
to increase policy justification at a regional level for wider autism support.
Uganda 2024-10-23 17:30:07 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Douglas Serwada
ID: UNCST-2024-R003939
Assessing The Influence of Climate Change on Sexual Reproductive Health Outcomes for Young People in Jinja and Mayuge districts-MAKSHSREC-2024-718
REFNo: SS3155ES

To investigate the psychosocial stressors related to climate change and their effects on young people SRH outcomes in Jinja and Mayuge districts.,To explore the relationship between resource scarcity and SRH outcomes among young people in Jinja and Mayuge districts.,To assess the impact of extreme weather events on the availability and accessibility of SRH services for young people in Jinja and Mayuge districts within the last 4-year period.,• To investigate the influence of climate change on the sexual and reproductive health (SRH) of young people in Mayuge and Jinja districts.,
Uganda 2024-10-23 17:26:31 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
Tuberculosis case finding at the completion of the Ubuntu clinical trial: a substudy to CoVPN 3008 (Ubuntu
REFNo: HS4739ES

Primary Objective 1: Identify participants with previously undiagnosed
tuberculosis (TB) disease, including subclinical TB.
Primary Objective 2: Identify demographic and other participant characteristics
that are associated with the diagnosis of TB, including subclinical TB.
Primary Objective 3: Investigate peripheral blood biomarkers associated with
diagnosis of TB, including subclinical TB.
Primary Objective 4: Follow participants with confirmed TB for six months and
identify those that remain microbiologically positive for TB.

Uganda 2024-10-23 17:24:22 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
Delivery strategies for post-discharge malaria chemoprevention (PDMC) in children with severe anaemia in African children: Formative research in Benin, Kenya, Malawi and Uganda
REFNo: HS4895ES

3. To develop user-friendly Job Aids for healthcare providers and IEC materials for health workers, CHWs and caregivers to promote effective service delivery and uptake.,2. To develop optimal packaging and information leaflets for PDMC drugs to optimise adherence by caregivers,1. To use the findings to finalise the design of the implementation trial to be conducted in two countries that will evaluate at least two of the preferred delivery strategies for PDMC most likely to optimise adherence. ,1. To explore the perceptions of national malaria programme managers, healthcare providers, community health workers and caregivers of hospitalised children in Benin, Kenya, Malawi and Uganda on PDMC and considerations for implementation in different contexts and assess preferences for choice of drug, drug regimen, and preferred delivery strategies for PDMC drugs taken in the home.,
Uganda 2024-10-23 17:22:44 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gabriel Iguma
ID: UNCST-2024-R003801
The Role of Sustainable Livelihoods in Enhancing Sexual and Reproductive Health Resilience to Climate Change Among Young People in Mayuge and Jinja Districts.-MAKSHSREC-2024-721
REFNo: SS3158ES

To investigate the role of sustainable livelihoods in enhancing the resilience of sexual and reproductive health (SRH) to climate change in Mayuge and Jinja districts.To assess the impact of sustainable livelihood practices on the availability and accessibility of SRH services in the context of climate change.To explore the relationship between improved livelihoods and SRH outcomes among young people in climate-affected areas.To identify and document community-based strategies that leverage sustainable livelihoods to mitigate the adverse effects of climate change on SRH.
Uganda 2024-10-23 17:20:45 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Deo Wabwire Ogema
ID: UNCST-2021-R013932
Tuberculosis Case Finding at the Completion of the Ubuntu Clinical Trial: A Sub-study to CoVPN 3008 (Ubuntu). Protocol version 1.0, 16 May 2024
REFNo: HS4828ES

Primary Objective 1: Identify participants with previously undiagnosed tuberculosis (TB) disease, including subclinical TB.

Primary Objective 2: Identify demographic and other participant characteristics that are associated with the diagnosis of TB, including subclinical TB.

Primary Objective 3: Investigate peripheral blood biomarkers associated with diagnosis of TB, including subclinical TB.

Primary Objective 4: Follow participants with confirmed TB for six months and identify those that remain microbiologically positive for TB.


Uganda 2024-10-23 17:19:34 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dennis Mwesigwa NA
ID: UNCST-2024-R003797
Integrating Sexual Reproductve Health into Climate Justice Movements: Perspectives from Young People with Disabilities in Jinja District.
REFNo: SS3203ES

To understand the integration of sexual and reproductive health (SRH) into climate justice movements from the perspectives of young people with disabilities in Jinja District. To explore the experiences and perceptions of young people with disabilities regarding the inclusion of SRH issues in climate justice movements.To document case studies of the successful integration of SRH into climate justice movements led by or involving young people with disabilities.To explore the role of community-based organisations in supporting the integration of SRH and climate justice for young people with disabilities.
Uganda 2024-10-23 17:17:23 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Zabibu Afazali
ID: UNCST-2024-R004457
An Assessment of Midterm Access: Beneficiary Perspectives of Makerere University Retirement Benefits Scheme (MURBS)
REFNo: SS3045ES

3. To examine MURBS members\' perspectives on the management of midterm access and pension funds.,2. Analyze the experiences and usage behavior pertaining to midterm access.,1. To investigate the factors influencing mid-term access and the underlying motivations.,To evaluate midterm access to pension funds by uncovering motivations, analyzing experiences and assessing management perspectives,
Uganda 2024-10-23 17:14:33 2027-10-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
CoVPN 3008- “UBUNTU TB SUB STUDY"; Tuberculosis case finding at the completion of the Ubuntu clinical trial
REFNo: HS4778ES

Overall objective: To identify individuals with undiagnosed TB, including subclinical TB, so they can be linked to care; and investigate blood biomarkers associated with TB diagnosis, particularly in populations living with HIV and other co-morbidities.

Primary Objectives:
• Identify participants with previously undiagnosed tuberculosis (TB) disease, including subclinical TB.
• Identify demographic and other participant characteristics that are associated with the diagnosis of TB, including subclinical TB.
• Investigate peripheral blood biomarkers associated with diagnosis of TB, including subclinical TB.
• Follow participants with confirmed TB for six months and identify those that remain microbiologically positive for TB.
Exploratory objectives
• Evaluate the tongue swabs as a diagnostic tool for TB.
• Determine the clinical relevance of trace results from Xpert MTB/RIF Ultra in TB diagnosis/management.
• Investigate the potential of an artificial intelligence-powered CAD system for TB diagnosis using chest radiographs.
• Assess associations of TB treatment with clinical outcomes and TB disease status.
• Evaluate the effect of TB treatment on TB-associated peripheral blood biomarkers measured after at the six-month follow-up time point.
• Undertake analyses aimed at improving our understanding of different TB screening or diagnostic strategies, and analyses at enhancing our understanding of TB immunology and pathophysiology, in the context of clinical and subclinical TB.


Uganda 2024-10-23 17:13:10 2027-10-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Mukhwana
ID: UNCST-2024-R002954
ROLE OF ASSISTIVE TECHNOLOGY IN ENHANCING INCLUSIVE SCIENCE EDUCATION OF STUDENTS WITH VISUAL IMPAIRMENT IN LOWER SECONDARY SCHOOLS IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS3141ES

4. To analyze the barriers and possibilities while using assistive technology in enhancing inclusive science education of Students with Visual Impairment in lower secondary schools in Uganda.,3. To explore the sighted peers’ opinion on assistive technology in enhancing inclusive science education of Students with Visual Impairment in lower secondary schools in Uganda.,2. To assess the professionals’ opinion on assistive technology in enhancing inclusive science education of Students with Visual Impairment in lower secondary schools in Uganda.,1. To study the role of assistive technology in enhancing inclusive science education of students with visual impairment in lower secondary schools in Uganda concerning the following dimensions; a) Accessibility b) Support Services c) Teaching and Learning Resources d) Assessment and Evaluation
Uganda 2024-10-21 16:31:28 2027-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
TUMWIJUKYE RUTH KOMUNDA
ID: UNCST-2023-R005625
CAPACITY BUILDING STRATEGIES AND PERFORMANCE OF LOCAL GOVERNMENT PERSONNEL IN KANUNGU DISTRICT, WESTERN UGANDA
REFNo: SS3273ES

To examine the intervening role of organizational culture on the relationship between capacity building strategies and performance of local government personnel Kanungu district.,To analyze the effects of training strategies on performance of local government personnel in Kanungu district,To assess the effects of participatory planning on performance of local government personnel in Kanungu district.,To examine the effects of empowerment on performance of local government personnel in Kanungu district.,The purpose of the study is to examine the effects of capacity building strategies on the effectiveness of personnel performance in local governance councils with Kanungu district, as a case study,
Uganda 2024-10-21 16:02:26 2027-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Susan Babirye
ID: UNCST-2021-R013201
Exploring the social norms surrounding Sexual and Gender-Based Violence and how these influence care and support for young survivors in Busia: An operations research
REFNo: HS5024ES

The overall objective of this study is to explore the different social norms surrounding SGBV in Busia and Mbale district, in terms of root causes, prevention, and response.,
Uganda 2024-10-21 16:00:50 2027-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Katungi
ID: UNCST-2024-R002472
A needs assessment for Early Childhood Care and Education (ECCE) services in selected Districts and the Development of a Training Package for the STRYIDE Initiative REF; MUREC-2024-477
REFNo: SS3245ES

1. Undertake a needs assessment related to availability and gaps of the ECCE services in the four target districts of Madi-Okollo, Terego, Kampala and Isingiro, including identification of the demand and appetite of parents and communities for parent-supported ECCE services and the interest of youth in working in ECD centres (running them as a business) and in the eco-system or support services that are related to the ECE Centres. a. Identify and evaluate the existing early childhood education services available in the four target districts and identify gaps and communities with little or no access. b. Assess the accessibility, affordability and quality of existing early childhood education services c. Identify any barriers or challenges hindering the provision or utilisation of early childhood education services, d. Explore potential opportunities for improvement and expansion of early childhood education services in the target Districts with the (financial) contribution of families (disaggregated by settlement and host communities, parishes, villages, etc.)., 2. Map, consolidate, and design a capacity-building training toolkit for young people on required core competencies, soft skills, innovation skills, technical and entrepreneurial aspects (including social enterprise development) of ECCE services based on existing training packages, including but not limited to those developed by UNICEF and UNCDF a. Mapping existing content and training packages covering the areas of ECCE services (e.g., the MoES, community child care programme, ECCE certificates, and diploma programmes, parenting programmes, caring for the caregivers package, and others), transferable skills, social innovation and entrepreneurship, digital and financial skills b. Consolidating a full training package combining relevant curricular/content outcomes and modules that can be implemented at scale c. Based on the consolidated package, develop a detailed training package map and detailed training plan for training master trainers to lead the cascading process. d. Produce a final design of the training package tailored for STRYIDE as an initiative titled STRYIDE toolkit. This includes the final toolkit with relevant handouts and training materials.
Uganda 2024-10-21 15:54:14 2027-10-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
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