Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Emmy Okello
ID: UNCST-2020-R009792
 “Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention” ADD-RHD "Part 2B"
REFNo: HS2351ES

Primary Objectives
Objective 1 (Aim 1): To determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by expert trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease.
Objective 2 (Aim 2): To determine the diagnostic performance (sensitivity and specificity) of secondary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by MOH nurse trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease.

Secondary Objectives:
• RHD and echocardiography knowledge
• Provider satisfaction with training curriculum
• Time to certification
• Screening volumes
• Longitudinal image quality
• Provider confidence
• Diagnostic performance for other common categories of cardiac diseases: moderate/severe left ventricular dysfunction, moderate/severe pericardial effusion.

 Uganda 2022-09-27 16:22:25 2025-09-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 A User-Centered Automated Two-way Messaging System to Support Prophylaxis Adherence in Rheumatic Heart Disease
REFNo: HS2411ES

1: Employ a user-centered design to develop a message bank and a two-way messaging intervention to support RHD secondary antibiotic prophylaxis in Uganda.

2: Compare patient-reported outcomes between RHD patients who receive standard prophylaxis support (current ACT platform) and those who receive enhanced prophylaxis support (current ACT platform + SMS intervention).

 Uganda 2022-09-27 16:15:50 2025-09-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rita Makabayi-Mugabe
ID:
Evaluation of barriers and facilitators to access to tuberculosis (TB) care in Uganda.
REFNo: HS2441ES

To find out barriers to access to TB care among patients and health workers in Uganda To find out facilitators to access to TB care among patients and health workers in Uganda To document intervention functions to alleviate barriers to and enhance facilitators for access to TB care in Uganda
Uganda 2022-09-23 12:52:32 2025-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 2019-nCoV Antigen Test (Later Flow Method) Diagnostic sensitivity and diagnostic specificity. "Clinical Performance Study Plan - CPSP nr. WON-CPH 22-038"
REFNo: HS2419ES

• Establish the diagnostic sensitivity and diagnostic specificity of the Wondfo 2019-nCoV Antigen Test (Lateral Flow Method) in a self-testing environment when performed by laymen and to provide data to demonstrate the product is safe and effective for its intended use. • To assess the usability of the self-test for its intended use by laymen, the laymen will be observed by healthcare professionals. These observations will be captured using a questionnaire-based survey.
Uganda 2022-09-23 12:49:47 2025-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 An Evaluation of the HIV Self-Testing 10X investment in Uganda
REFNo: HS2397ES

1. To determine (i) impact of HIVST within priority populations and (ii) demonstrate the demographics of those taking up testing and (iii) identify target populations not being reached
2. Identify the gaps in the HIV prevention and care cascades from distribution of HIVST kits to confirmatory testing, linkage to care and provision of ART or preventative services
3. Determine the health provider costs of different HIVST distribution models, and which models or combination of models are cost-effective for policy makers in Nigeria and Uganda to implement.

 UK 2022-09-23 12:46:13 2025-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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