Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,731
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Brandon Maser
ID: UNCST-2024-R005142
 Understanding How Policies, Politics, and National Contexts Influence Access to Opioid Medicines in Uganda
REFNo: HS4768ES

1) To elucidate the policy mechanisms that are used by policymakers to govern access to and safe use of opioid medicines in Uganda. 2) To understand how political factors and national context influence the political priority for improving access to opioid medicines within Uganda’s national government’s policy agenda. 3) To understand how political factors and national context influence how governmental, non-governmental, and transnational actors formulate alternative policy options for ensuring access to opioid medicines in Uganda. 4) To understand how policies governing opioid analgesics and those governing OAT have been uniquely influenced by political factors and national contexts during Uganda’s opioid policy reforms.
 Canada 2024-09-10 10:26:35 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Busiku
ID: UNCST-2024-R004040
 Validity, Feasibility and Acceptability of digital x-ray Computer Aided Diagnosis for Tuberculosis by Village Health Teams in Bududa District- a cross-sectional study
REFNo: HS4792ES

3. To determine the feasibility and acceptability of portable Digital Chest X-ray CAD4TB version 7 by VHTs in Bududa District.,2. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to ZN in Bududa District.,1. To determine the validity of portable Digital Chest X-ray CAD4TB version 7, compared to X-pert MTB/RIF (x-pert) in Bududa District.,To evaluate the diagnostic accuracy of portable CXR CAD4TB as Community TB diagnostic tool in Bududa District in Uganda.,
 Uganda 2024-09-10 10:17:27 2027-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Peer-led Implementation of TB-HIV Education and Adherence Counselling in Uganda
REFNo: HS4801ES

To evaluate the implementation fidelity and context of a peer-navigation strategy for TB-EC to improve TB treatment and ART outcomes, To determine the feasibility, acceptability, and appropriateness of a peer-navigation strategy for TB-EC and explore the social-behavioral mechanisms for improving adherence and clinical outcomes. ,To evaluate the implementation of a peer-navigation strategy for TB-EC to improve TB treatment completion and ART retention. , To evaluate the effectiveness and implementation of a novel, peer-led TB education and counseling strategy to improve outcomes among persons with tuberculosis (TB) with and without HIV/AIDS and assess the social-behavioral mechanisms underlying the observed treatment effects. ,
 Uganda 2024-09-10 10:03:57 2027-09-10 Medical and Health Sciences Clinical Trial Non-degree Award
Okumu Tendo Ivan
ID:
Assessment and remediation of selected heavy metals contaminants in tannery wastewater from selected tanneries in Jinja city and Wakiso district,Uganda
REFNo: NS795ES

Prepare and characterize biochar using green banana peels and coffee husks ,Evaluate the concentration levels, speciation and toxicity of selected heavy metals( Cr,Cu,NI,Pb and Zn) in tannery wastewater.,To assess the concentration levels and to bioremediate selected heavy metals contaminants in tannery wastewaters from designated tanning industries in Uganda,
 Uganda 2024-09-10 10:01:32 2027-09-10 Natural Sciences Non-Clinical Trial Degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
 Community Development Intervention Strategies and Poverty Alleviation in Wakiso District
REFNo: SS3067ES

(iv) Explore how interactions among development actors affect poverty alleviation in Wakiso district,(iii) Assess if, and to what extent, multipurpose cooperative societies leverage community development intervention strategies in poverty alleviation in Wakiso District,(ii) Analyse the relationship, if any, between the various development strategies and the selected poverty outcomes (income, food security, household assets, agency),(i) Understand how the communities in Wakiso district perceive poverty and development,To generate, using a systems approach, more contextualized knowledge on the effects of skills acquisition, transfers and financial inclusion supported by non-governmental organisations through cooperatives on household income, assets, food security and agency. ,
 Uganda 2024-09-10 10:00:24 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Riccardo Durini
ID:
Comparison in sociality in snared and non-snared chimpanzees
REFNo: NS861ES

The goal is to analyse social behavioural differences between snared and healthy chimpanzee individuals. The comparison focuses on certain traits related to sociality, such as the number and quality of bonds with other individuals, party formation, grooming partners and others.
 Switzerland 2024-09-09 14:54:20 2027-09-09 Natural Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of the performance of HIV rapid diagnostic tests on Oral Fluid and Urine for WHO prequalification assessment.
REFNo: HS4871ES

To describe and assess the operational characteristics and ease of use of HIV RDTs on urine or oral fluids and its suitability for use in countries with limited infrastructure (no/limited electricity, no/limited clean water, and inadequate means of biosafety disposal).,To assess inter-reader variability (for subjectively read assays),To assess analytical performance of HIV RDTs for the detection of antibodies to HIV in oral fluid and urine: ● Sensitivity on seroconversion panels compared to a benchmark assay ● Performance on mixed-titer panels ● Subtype detection ● Lot-to-lot variation ,To determine the sensitivity and specificity of HIV RDTs for the detection of antibodies to HIV in oral fluids and urine as compared to a reference algorithm (two EIAs followed by a line immunoassay) in blood- derived specimen and compare them to predefined acceptance criteria for prequalification,The overall objective is to evaluate and compare the accuracy of HIV rapid tests for the detection of HIV antibodies in oral fluids and urine against established performance criteria. ,
 Uganda 2024-09-04 18:43:09 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY NUWA
ID: UNCST-2022-R011102
 Using behavioural insights to design a behavioural intervention to accelerate malaria mosquito net use in Uganda: The Be In A Net study
REFNo: SS3095ES

1. The aim of this study is to understand the behaviours, barriers, and facilitators affecting the use of insecticide-treated nets (ITNs) in selected areas of Uganda in order to develop a behavioural intervention to increase ITN use,To design and refine a behavioural intervention to increase mosquito net use based on behavioural science principles.,To conduct exploratory research to examine the role of psychological, cognitive, emotional, cultural and social factors impacting ITN use to inform the design of a behavioural intervention to encourage mosquito net use.,
 Uganda 2024-09-04 18:41:43 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
molly naisanga
ID: UNCST-2023-R005602
 Mental Health and Psychosocial Support Services for Refugee Children and Adolescents with HIV in West Nile Uganda.
REFNo: HS4486ES

2. To explore experiences with available mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda.,1. To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda,To explore ongoing and past mental health and psychosocial support services for HIV-positive school going refugee children and adolescents in the West Nile region of Uganda and to explore their experiences with available mental health and psychosocial support services.,
 Uganda 2024-09-04 13:33:35 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olak Ongaya Denis
ID:
Scaling-up innovative Gender, Inclusion and Safeguarding Approaches: Evidence from Malawi, Uganda and Ethiopia
REFNo: SS2919ES

• Strengthen capacities of education managers at all levels to identify and address bottlenecks in the delivery of equitable and quality education at the school level.,• To Mobilize knowledge on optimal use of school-based data for education decision-making, policy and management amongst education stakeholders.,• To gather and develop guidelines on best practices of scale-up, which will be adopted and resourced by the government to develop capacity, influence, and improve education policy and practice on scale-up of GEI interventions,• To generate knowledge that contributes to a broader understanding of the factors of scale-up to guide stakeholders, including policymakers and other researchers on future GEI education interventions and scale-up strategies. ,To contribute to the understanding and improvement of scale-up practices of GEI-focused education projects at local, regional, and international levels.,
 Uganda 2024-09-04 12:57:16 2027-09-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Katende
ID:
Characterization of New Childhood HIV Infections in USAID supported regions in Uganda (NCHiS)
REFNo: HS4857ES

The assessment aims to characterize those children newly diagnosed with HIV in terms of their demographics, geography, access to care, care continuum and social determinants, to inform child HIV services on targeted and effective case finding and treatment services that can support the reversal of sub-optimal case finding and viral load suppression, and the stagnation in the overall rate of new vertical infections.
a. Primary objective
To describe the determinants or associated risk factors of persisting vertical HIV infections among children.
b. Secondary objectives
i. To report on the perspectives of key stakeholders on the utilization of child HIV services from implementor to the recipient.
ii. To describe the distribution of HIV seropositive children by HIV acquisition mode e.g., vertical MTCT (PMTCT and non-PMTCT), BF, through sex, trauma/GBV.
iii. To establish the proportion of uniquely identified HIV seropositive children in the survey region.

 Uganda 2024-09-04 11:10:19 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Understanding the causes of deaths amongst persons with Rheumatic Heart Disease in Uganda
REFNo: HS4663ES

Main objective: To identify the causes of death among RHD registrants in the National RHD registry in Uganda
 Uganda 2024-09-02 15:12:28 2027-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Babirekere Iriso
ID: UNCST-2024-R005372
 International Investigation into the Genetics of Severe Acute Malnutrition in Children
REFNo: HS4569ES

Determine the contributions of genetic markers to the development of ESAM vs NESAM and its clinical characteristics Elucidate the role of epigenetic mechanisms in the development of ESAM vs NESAM
 Uganda 2024-08-30 15:11:38 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Larison Jean
ID:
Investigating the Genetic Causes of Malformed Stripe Patterns in Plains Zebras
REFNo: NS831ES

Our primary objective is to understand the causes (specific genes, low heterozygosity) of abnormal striping in plains zebras

Specific Objectives:
1. Collect samples from both individuals with abnormal striping and normal striping in order to discover the genes associated with the various forms of abnormal striping

2. Use these same samples to further assess the potential relationship between aberrant striping and genomic heterozygosity
 USA 2024-08-30 15:05:53 2027-08-30 Natural Sciences Non-Clinical Trial Non-degree Award
Barnabas Bakamutumaho
ID: UNCST-2021-R012636
 MULTIDIMENSIONAL AND LONGITUDINAL IMMUNE PROFILING OF SEPSIS IN UGANDA
REFNo: HS4546ES

General Objective:
The overall goal of this project is to stratify sepsis patients in Uganda into biologically driven and therapeutically relevant subtypes.
Specific Aims/Objectives:
(1) Establish pathobiologically-driven and clinically meaningful sepsis endotypes in Uganda
(2) Define longitudinal immune response trajectories associated with sepsis-related death and disability
(3) Determine immune cell phenotypes and function unique to sepsis in persons living with HIV (PLWH).

Uganda 2024-08-30 15:04:57 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Akankwasa
ID:
Evaluation of the Comprehensive and Inclusive Disability Prevention Project in Nakaseke and Nakasongola Districts.
REFNo: SS2991ES

• To establish the extent to which the CIDP project has built the capacity of formal and informal structures to facilitate comprehensive and inclusive disability programming in the two districts of Nakaseke, Nakasongola.
• To assess the degree to which the CIDP project has provided quality, comprehensive and inclusive disability prevention services with focus on primary, secondary and tertiary prevention in the two districts of Nakaseke, Nakasongola
• Determine the extent to which the CIDP project has strengthened participatory advocacy, social protection, and poverty reduction through community-driven innovations in the two districts of Nakaseke, Nakasongola
• To assess the impact of the CID project on the evidence base on comprehensive Disability programming through action research, monitoring, evaluation and learning.

 Uganda 2024-08-30 14:56:58 2027-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lisa Dulli
ID: UNCST-2024-R004307
 Community-based mentorship for out-of-school youth in Adjumani and Buyende Districts, Uganda: An implementation research study
REFNo: SS2789ES

a secondary objective we will document the experiences of youth mentoring program participants who seek SRH services within the community, and their perspectives with regard to the quality and responsiveness of the services to their needs.,the study’s primary objective is to examine key aspects of implementation for the SHARE project mentoring activities targeting AGYW and ABYM, including reach, effectiveness, adoption, implementation, maintenance (including cost), and external and internal (organizational) contexts in two settings.,
 USA 2024-08-30 14:55:02 2027-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Bibangambah Mulungi Nabatanzi
ID: UNCST-2024-R004669
 Assessing the awareness and understanding of Duchenne Muscular Dystrophy among health workers and community members in Uganda.
REFNo: HS4766ES

Evaluate the impact of health education awareness drive program on mitigating the knowledge gap of DMD among health workers and the community(s) in Uganda. ,To ascertain the Prevalence of Clinical Duchenne Muscular Dystrophy in Uganda. ,To assess the knowledge gaps of Duchenne Muscular Dystrophy among health workers and the various community members in Uganda.,The overall goal of the research is to assess the knowledge, insight, and perception of DMD among health workers and the community. ,
 Uganda 2024-08-29 18:54:13 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Kalenzi
ID:
Succession planning factors, transition process and the continuity of small and medium-size family businesses in Fort Portal City Uganda
REFNo: SS2862ES

i. To examine the influence of internal succession planning facets on family business continuity in Fort Portal Tourism City, Uganda. ii. To assess the influence of external succession planning facets on family business continuity in Fort Portal Tourism City, Uganda.
iii. To investigate the mediating influence of succession process (transition) on the relationship between succession planning facets and family business community in Fort Portal Tourism City.

 Uganda 2024-08-29 18:50:55 2027-08-29 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
 ASSESSMENT OF CARDIOVASCULAR DISEASE (CVD) POLICY IMPLEMENTATION IN UGANDA - DEVELOPMENT & OPTIMIZING A POLICY MONITORING TOOL USING ROUTINE HEALTH DATA
REFNo: HS4649ES

1.To characterize CVD policy environments and identify the data-specific determinants of policy design and implementation in Uganda a. Specifically, we will use hypertension policy as an example condition to trace the policy processes in each country. Aim 1 has two components:

2.To develop a CVD policy monitoring tool that uses routine health data in Uganda to CVD policy implementation at health center level II & III.

3. To develop a proof-of-concept policy modeling tool that links routine health data to policy analysis in Uganda.

 Uganda 2024-08-29 18:49:22 2027-08-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS