Jackson Orem
ID: UNCST-2021-R012016
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A Phase II Multicenter Study of Pomalidomide Monotherapy in HIV-Positive Individuals with Kaposi Sarcoma (KS) in Sub-Saharan Africa (SSA)
REFNo: HS2367ES
To evaluate if changes in serum cytokine levels correlate with clinical response.,To assess the effect of pomalidomide treatment on serum cytokine levels.,To evaluate the effects of pomalidomide monotherapy on standard measures of HIV control, i.e., CD4 counts and HIV viral loads, in this participant population.,To determine if pomalidomide monotherapy induces a minimal level of antitumor efficacy to justify its further development for HIV-associated KS in sub-Saharan Africa and is safe and tolerable.,
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Uganda |
2022-11-08 13:27:55 |
2025-11-08 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Simons Ezajobo
ID: UNCST-2021-R012010
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Uptake of HIV Testing Services through Assisted Partner Notification (APN) among Men in Wakiso District.
REFNo: HS2537ES
2.To understand the preferred partner notification approaches to help men feel more comfortable and confident in getting tested for HIV.,1.To assess the experience of males during the process of HIV testing services provision.,To identify barriers and facilitators to HIV testing among men in Uganda,
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Uganda |
2022-11-08 13:23:56 |
2025-11-08 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Catriona Waitt John
ID: UNCST-2019-R001068
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PHARMACOKINETICS OF DRUGS USED TO TREAT UNCOMPLICATED MALARIA IN BREASTFEEDING MOTHER-INFANT PAIRS
REFNo: HS2392ES
Primary Objectives;
1. To define transfer of lumefantrine and its active metabolite, desbutyl-lumefantrine from mother to breastfed infant.
2. To determine the clearance, AUC, and volume of distribution of lumefantrine and desbutyl-lumefantrine
Secondary Objectives
1. To describe covariates influencing drug exposure in maternal plasma, breast milk and infant plasma
2. To develop a population pharmacokinetic model including the breast and the infant as compartments, which will both enable optimal use of sparse data from future studies and enable simulations of different doses or combinations.
3. To assess depression and anxiety levels among breastfeeding mothers on first line antimalarial drugs.
4. Beliefs about medicines in breastfeeding mothers receiving antimalarial treatment
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UK |
2022-11-04 16:05:41 |
2025-11-04 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Dinah Amongin
ID: UNCST-2020-R014663
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Innovations for continuity of HIV, TB and malaria services during the COVID-19 pandemic in Uganda
REFNo: HS2477ES
The goal of this research is to collate and assess the impact of innovative people-centred and community-based approaches adopted during the covid-19 pandemic to ensure continued HIV, TB and malaria services in Uganda. This will inform the ongoing and future pandemic/epidemic response actions.
Specific objectives are:
1. To identify innovations used to mitigate the impact of the covid-19 pandemic on the provision, access, and utilization of HIV, TB and Malaria services in Uganda.
2. To assess the impact of innovations to mitigate the impact of the COVID-19 pandemic on HIV, TB, and Malaria services provision, access, and utilization.
3. To document the lessons learnt in innovating to mitigate the impact of COVID-19 on HIV, TB and malaria services in Uganda during the pandemic.
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Uganda |
2022-11-03 12:21:51 |
2025-11-03 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Albert Munyeshyaka
ID:
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Cosmological studies in modified Gauss-Bonnet gravity
REFNo: NS434ES
To determine evolution of overdensities and velocity perturbations in f (G) grav- ity,To analyse perturbations of a Chaplygin gas model in f (G) gravity,To analyse covariant velocity and overdensities of quasi-Newtonian cosmological model in f (G) gravity,To derive evolution of 1 + 3 covariant linear perturbation equations in f (G) gravity.,The aim of this study is to explore cosmological studies in modified Gauss-Bonnet gravity.,
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Rwanda |
2022-11-03 12:09:30 |
2025-11-03 |
Natural Sciences |
Non-Clinical Trial |
Degree Award |
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