Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Helen Byakwaga
ID: UNCST-2019-R001168
CD4 Cell Count at Antiretroviral Therapy Initiation or Re-initiation (CAIR)
REFNo: HS4944ES

To assess advanced HIV disease among people living with HIV initiating or re-initiating ART 1) Assess the proportion of participants presenting with advanced HIV disease prior to ART initiation/re-initiation among those enrolling in HIV care via CD4 cell count testing and WHO staging. 2) Description of participants re-entering care based on viral suppression and/or self-report of HIV care. 3) Assess barriers to HIV care including barriers associated with mental health and alcohol use. 4) Pilot test data variables to capture re-entry into care and re-initiation of ART and barriers to HIV care and ART
Uganda 2024-09-23 12:08:10 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MUGABE AMOS
ID: UNCST-2023-R007328
OCCURRENCE, ANTIMICROBIAL AND HEAT RESISTANCE PROFILES OF SALMONELLA SPECIES IN THE INFORMAL DAIRY VALUE CHAIN OF UGANDA
REFNo: A514ES

5. Evaluate the heat resistance profiles of Salmonella in the dairy value chain.,4. Evaluate the antibiotic resistance profiles of Salmonella in the dairy value chain.,3. Determine the serotypes of Salmonella in the dairy value chain. ,2. Estimate the prevalence of Salmonella in the dairy value chain.,1. Determine the extent to which milk producers and handlers in the dairy value chain are aware of milk quality and best dairy practices. ,To assess the serotypes, antibiotic resistance and heat resistance profiles of Salmonella in the dairy chain.,
Uganda 2024-09-23 12:05:28 2027-09-23 Agricultural Sciences Non-Clinical Trial Degree Award
Emmanuel Mande
ID: UNCST-2023-R007045
Artemisinin Resistance Surveillance Network in Sub-Saharan Africa (ARSUNA)
REFNo: HS4644ES

To evaluate socio-demographic, clinical and malaria-history factors on treatment outcome and on the carriage of resistant malaria parasites.,To evaluate day 3 parasitemia among 200 patients with P. falciparum malaria treated with an ACT.,To assess the relatedness and origin of P. falciparum isolates with an artemisinin resistant geno- and phenotype by molecular analysis. ,To evaluate the in vitro susceptibility to (dihydro) artemisinin and ACT partner drugs (e.g. lumefantrine) among selected/suspicious P. falciparum isolates.,To assess the molecular characteristics of P. falciparum isolates from 200 patients with malaria, with a special focus on, but not limited to, molecular markers of artemisinin resistance, e.g., K13, and Pfmdr1.,
Uganda 2024-09-23 11:59:33 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
Uganda Malaria Indicator Survey 2024
REFNo: HS4950ES

To determine risk factors for malaria parasitemia in Uganda,To measure indicators of knowledge, attitudes, and behaviour related to malaria control in Uganda (Community prevention and control efforts, Malaria vaccine knowledge and acceptance),To estimate core malaria programme coverage indicators in Uganda (Measure the extent of ownership, use and disposal of mosquito bed nets ● Assess coverage of the IPTp programme for pregnant women ● Coverage and uptake of IRS ● Identify practices used to treat malaria among children under age 5 and the use of specific antimalarial medications ● Assess percent of children under five with suspected or confirmed malaria who received treatment with ACTs within 24 hours of onset of fever. ● Access to malaria testing/ diagnosis ● Coverage, attitudes, and perceptions about SMC ● Determine the species of plasmodium parasite most prevalent in Uganda ),To obtain estimates of the magnitude and distribution of malaria parasitemia among children aged 6-59 months in Uganda,The main objective of the UMIS is to obtain population-based estimates of malaria indicators including the prevalence of malaria, to inform strategic planning and programme evaluation,
Uganda 2024-09-23 11:57:13 2027-09-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
ESTABLISHMENT OF A PEDIATRIC CANCER PATIENT NAVIGATION PROGRAM
REFNo: HS4909ES

1. To determine the barriers and facilitators of accessing care and remaining in care at Mulago National Referral Hospital, Pediatric Hematology and Oncology service 2.To develop a patient centered navigation program for patients seeking care and in care for cancer at MNRH 3.To determine the patient - parent navigation requirements in seeking and remaining in cancer care program at MNRH
Uganda 2024-09-13 11:00:38 2027-09-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alimah Komuhangi
ID: UNCST-2020-R014709
EFFECTIVENESS AND CONTEXTUAL FACTORS OF COMMUNITY-BASED PEER-LED SEXUAL AND REPRODUCTIVE HEALTH EDUCATION ON RISKY SEXUAL BEHAVIOUR FOR ADOLESCENT GIRLS AND YOUNG WOMEN IN MOROTO DISTRICT, KARAMOJA REGION.
REFNo: HS4697ES

To establish the preliminary effectiveness of the community-based peer-led sexual and reproductive health education on SRH knowledge among AGYW in Moroto District.,To determine the preliminary effectiveness of the community-based peer-led sexual and reproductive health education on risky sexual behavior among AGYW in Moroto District.,To explore the contextual factors that might influence the implementation of a CBPL SRH education among AGYW in Moroto District.,To explore the contextual factors that might shape the implementation of a community-based peer-led sexual and reproductive health education and its effectiveness on SRH outcomes among AGYW in Moroto District.,
Uganda 2024-09-13 10:18:43 2027-09-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Mohammed Kisu Aata
ID:
INFLUENCE OF INSTRUCTOR COMPETENCES ON EFFECTIVE ONLINE TEACHING IN TVET INSTITUTIONS IN UGANDA. Research Number UCUREC-2024-904
REFNo: SIR370ES

The main objective of the study is to evaluate how various instructor competences influence effective online teaching in TVET institutions in Uganda and to offer insights and recommendations to enhance the effectiveness of online teaching in TVET.,iv). To analyze the influence of instructors\' capacity to utilize digital teaching platforms on effective online teaching in TVET institutions in Uganda.,iii). To assess the influence of instructors’ evaluation and assessment competences on effective online teaching in TVET institutions in Uganda.,ii). To establish the influence of TVET instructors\' pedagogical competences on effective online teaching in TVET institutions in Uganda.,i). To determine the influence of TVET instructors\' online classroom management on effective online teaching in TVET institutions in Uganda.,
Uganda 2024-09-13 10:14:44 2027-09-13 Engineering and Technology Non-Clinical Trial Degree Award
Daniel  Atwine Warren
ID:
Post-Tuberculosis: Sequelae and its Impact on Quality of Life in Sub-Saharan Africa.
REFNo: HS4038ES

Primary objective
To study the association between the presence of post-tuberculosis lung disease (PTLD) and the deterioration of the quality of life in the medium and long term in people who have been treated for pulmonary tuberculosis within the framework of 5 therapeutic trials in sub-Saharan Africa (SSA) (Benin, Guinea and Uganda)
Secondary objectives
• Describe the clinical, radiological, functional respiratory, psychological, socio-economic characteristics and the quality of life of the people evaluated after the end of their anti-tuberculosis treatment within the framework of therapeutic trials in SSA;
• Estimate the prevalence of PTLD in the medium and long term after the end of anti-tuberculosis treatment in people who took part in the various therapeutic trials, taking into account missing data in people who could not be assessed in the Post-TB SIQ study;
• Identify the factors (at the time of TB diagnosis and at the end of treatment) associated with the presence of PTLD in people assessed after completing their TB treatment;
• Describe the care path of people suffering from PTLD and the modalities of recognition of PTLD in Benin, Guinea and Uganda within the framework of care interactions (conventional and traditional medicine) (qualitative study);
• To assess the impact of a pulmonary functional rehabilitation program on quality of life and respiratory function.

Uganda 2024-09-12 9:52:11 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olanya Gilbert
ID:
INDIVIDUAL CHARACTERISTICS AND WORK ENGAGEMENT OF PRIMARY SCHOOL TEACHERS MODERATED BY ORGANISATIONAL FACTORS IN ACHOLI SUB-REGION
REFNo: SS3178ES

-To determine the influence of Demographic factors on career engagement among primary school teachers.
-To examine the individual factors that influence career engagement among primary school teachers in Acholi sub-region.
-Access organization support factors that influence career engagement among primary school teachers
-To determine the mediating role of psychological role in the relationship between individual and organization support factors influencing career engagement among primary school teachers.

2024-09-12 8:48:36 2027-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
CLINICAL PERFORMANCE EVALUATION OF THE ALINITY M HIV-1 ASSAY USING DBS FOR WHO PREQUALIFICATION
REFNo: HS4873ES

To describe the operational characteristics and ease of use of the assays and their suitability for use in countries with limited infrastructure. ,To assess the Alinity m HIV-1 assay’ s agreement with the Cobas HIV-1 assay on clinical specimens on Misclassification above or below the clinical threshold.,To assess the Alinity m HIV-1 assay’ s agreement with the Cobas HIV-1 assay on clinical specimens on Quantitative assessment of bias limits of agreement and correlation. ,The overall objective of the performance evaluation is to evaluate the clinical performance and operational characteristics of Alinity m HIV-1 assay intended for the quantification of HIV viral load in HIV-infected individuals using DBS samples. ,
Uganda 2024-09-12 12:07:38 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Boyenge Eddie Francis
ID:
Barriers and enablers of psychosocial stimulation support delivered through the care group strategy for malnourished children of 6 to 35 months in the Kyaka II refugee settlement
REFNo: HS4820ES

• To compare the developmental status of malnourished children exposed to the integrated intervention of psychosocial stimulation and nutritional support delivered through the care group model before and after the intervention.
• To explore the factors that influence the adoption of this integrated intervention delivered by trained care group volunteers
Uganda 2024-09-12 11:56:25 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Muhindo
ID:
Integrating Long-Acting Injectable Cabotegravir for HIV Pre-exposure Prophylaxis into HIV services for sex workers in Uganda
REFNo: HS4747ES

2. To describe the CAB-LA PrEP service delivery attributes, and preferred delivery models among MSW and FSW. ,To identify the facilitators of and barriers to integrating CAB-LA PrEP into existing HIV services for MSW and FSW,To examine the barriers to and facilitators of integrating CAB-LA PrEP into existing HIV prevention services and describe the PrEP service delivery attributes and preferred delivery models among MSW and FSW,
Uganda 2024-09-12 11:43:32 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
STEPWISE INTERVENTION TO IMPROVE MENTAL HEALTH AND INCLUSION FOR CHILDREN WITH STOMAS IN UGANDA.
REFNo: HS4879ES

Aim 1: Perform a qualitative study to understand the stigma faced by patients and their families, the coping mechanisms they have tried, and the degrees of success or failure they have met with current interventions.

Aim 2: Develop and Pilot a stepwise psychological & stoma care intervention based on theories of cognitive behavioral therapy, coping models, and stoma resources available in Uganda.
Uganda 2024-09-12 11:41:59 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HADIJAH NAMYALO-GANAFA
ID: UNCST-2022-R010694
The Identification Gap: Exploring Intersectional Exclusions and Disconnections in Digital Identification for Health in Uganda
REFNo: SS2863ES


Understanding the nexus between digital IDs and healthcare access

To find out the institutions and power relations that shape the identification ecosystem in postcolonial Uganda and who benefits from it.

Exploring the role of the law in defining the eligibility for acquisition of IDs and their use in accessing services in Uganda.

Uganda 2024-09-12 11:37:48 2027-09-12 Social Science and Humanities Non-Clinical Trial Degree Award
Betty Adoch
ID: UNCST-2024-R003825
Role of Social Capital in Facilitating Access to Livelihoods among Refugees in Post-Conflict Gulu City, Uganda
REFNo: SS2820ES

3. To establish the barriers and opportunities for social capital formation and utilization among refugees in post-conflict Gulu city.,2. To assess the influence of social capital on refugees’ access to livelihoods in post-conflict Gulu city.,1. To examine the forms of social capital experienced by refugees in post-conflict Gulu city. ,To examine the forms of social capital among refugees and how these influences access to livelihoods. This will inform policies and interventions geared towards urban refugees’ livelihoods and integration in post-conflict Gulu city. ,
Uganda 2024-09-12 11:27:24 2027-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
The Phosphatidylethanol (PEth) Results Communication (PERC) Study
REFNo: HS4449ES

Main Objective: To develop and pilot strategies for using PEth results communication to boost alcohol brief interventions for PWH and explore their acceptability, appropriateness, and feasibility for a future large-scale Randomized Controlled Trial. AIM 1: Develop approaches for adding PEth results communication to alcohol brief interventions. AIM 2. Explore the acceptability, appropriateness, and feasibility of adding PEth results communication to an alcohol brief intervention in a pilot randomized controlled trial (RCT).
Uganda 2024-09-12 11:23:21 2027-09-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angelina Kakooza-Mwesige
ID: UNCST-2020-R014529
Digital Evidence Communication for Intelligent Decisions: how PHC managers support community health worker to screen chronic disease (DECIDE PHC) REF NO;SBS-2024-545
REFNo: SS2773ES

2. To describe the outputs and outcomes resulting from the use of performance information by health assistants in supporting VHTs’ decisions around screening of NCDs (diabetes and epilepsy) in Buikwe district. ,1. To characterize the contextual barriers and facilitators influencing the use of digital data by health assistants in providing performance feedback to VHTs in Buikwe district.,To explore how Primary Health Care (PHC) managers (particularly health assistants) use digital evidence to support Village Health Team (VHT) members to improve processes for screening non-communicable diseases (NCDs) in the community in Buikwe district.,
Uganda 2024-09-12 11:13:46 2027-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
Neo-EPIC: A Study to Explore Preferences for Informed Consent processes in Neonatal Sepsis Research, version 2.0 April 17, 2024
REFNo: SS2682ES

Primary Objectives
• To characterize parents, guardians, and clinical staff’s knowledge about informed consent
(IC) processes for involvement of neonates in trials.
• To determine parents, guardians, and clinical staff’s preferences for an optmal informed
consent model for enrolment of neonates in trials by utlizing example scenarios of
different Informed consent models.
• To explore parents, guardians’ and clinical staff concerns about enrolment and informed
consent processes for trials in neonates to facilitate involvement of neonates in future
trials.

Secondary Objectves
• To understand regulators’ perspectves of Informed Consent models preferred by parents,
guardians, and clinical staff for enrollment of children with neonatal sepsis in research
Uganda 2024-09-12 11:11:49 2027-09-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Morgan Andama
ID:
Safeguarding Common Drinking Water Sources for Improved Health and Educational Performance in Selected Schools in Arua District
REFNo: NS781ES

1. To establish the common drinking water sources used by pupils in selected primary schools in Vurra subcounty, Arua District and the health and educational impacts they pose to them. 2. To determine the water sources, water use and its challenges in communities surrounding selected primary schools in Vurra sub county, Arua District. 3. To carry out sanitary risk assessment of selected commonly used water sources (boreholes, springs and shallow wells, tap water, harvested water) used by pupils in the selected primary schools in Vurra subcounty. 4. To determine the suitability of water from the selected commonly used water sources (boreholes, springs and shallow wells, tap water, harvested water) for human consumption.
Uganda 2024-09-12 11:05:59 2027-09-12 Natural Sciences Non-Clinical Trial Non-degree Award
Lawrence Osuwat Obado
ID: UNCST-2023-R008389
CHARACTERIZATION OF PHENOTYPES AND MOLECULAR GENOTYPES OF BREAST CANCER: A RETROSPECTIVE STUDY AT HISTOPATHOLOGY CENTRES IN UGANDA
REFNo: HS4751ES

To establish the prevalence of mutations and the clinical significance of the identified variants ,To characterize gene variants from DNA of the sampled materials,To categorize the molecular subtypes of the tumors from retrieved tissues,To determine the demographics and histological phenotypes of BC from archived materials,Overall, this study seeks to use archived breast tissues and clinical notes for the investigation of underlying gene mutations and the relationship between demographics, pathological phenotypes, and intrinsic molecular sub-types of BC in Uganda, done through four sub-studies.,
Uganda 2024-09-12 11:02:37 2027-09-12 Medical and Health Sciences Non-Clinical Trial Degree Award
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