Achilles Katamba
ID: UNCST-2019-R000540
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Clinic versus Hotspot Active Case Finding and Linkage to TB Preventive Therapy (ACF/TPT) Strategy Evaluation for Tuberculosis
REFNo: HS2166ES
3. To estimate (using simulation) the impact of each intervention on diagnostic delays and TB prevalence.,2. To measure the implementation of hotspot-based and facility-based ACF + TPT, including the reach (number of individuals willing to be screened), implementation (measured via cascades of care), and maintenance (of effectiveness over time).,1. To compare the effectiveness of hotspot-focused versus facility-based ACF + linkage to TPT in terms of the number of individuals started on treatment for microbiologically confirmed TB in each community (i.e., reduction in undiagnosed TB prevalence, primary outcome) ,
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Uganda |
2022-05-18 9:43:01 |
2025-05-18 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Penlope Yaguma
ID:
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Electricity access in Uganda's urban slums
REFNo: SS1036ES
Main objective: To investigate the electricity access challenges faced by households and businesses in Nankulabye slum, Kampala, Uganda
Specific Objectives
1. To identify the key socio-economic factors that influence electricity access in the slum
2. To model the daily load profile of a typical household and business in the slum
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Uganda |
2022-05-18 9:32:25 |
2025-05-18 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Ponsiano Ocama
ID: UNCST-2019-R001799
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Prevention of Mother to child transmission of Hepatitis B virus in Uganda: the effect of Birth dose and antiviral therapy on neonatal transmission
REFNo: HS2201ES
Specific objectives
1. To determine prevalence of HBsAg in mothers attending antenatal care in the selected hospitals in Uganda
2. To determine the prevalence of HBsAg among 9-12month-old infants who received the HBV birth dose vaccination and the HBV 3 dose vaccinations and born to HBsAg+ve mothers who had viral load <20,000IU/ ML and never received TDF treatment.
3. To determine the HBsAg prevalence among 9-12month-old infants who received the HBV birth dose and the HBV 3 dose vaccinations and born to HBsAg+ mothers who had a viral load ?20,000 IU/ML and also received 3 months of TDF treatment.
Secondary objectives
a) Assess HBV viral load among pregnant women in different regions of Uganda.
b) Assess the predictor relationship between HBeAg and HBV viral load to transmission of the infection to unborn babies among pregnant women.
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Uganda |
2022-05-18 17:20:32 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Muge Cevik
ID: UNCST-2022-R011548
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Unravelling the role of host microenvironment in the development of phenotypic resistance in Mycobacterium Tuberculosis
REFNo: HS2010ES
1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.
3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes
2. To identify risk factors for poor treatment response among patients with DM and TB 1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.
3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes
2. To identify risk factors for poor treatment response among patients with DM and TB
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UK |
2022-05-18 17:18:33 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Stephen Tukwasibwe
ID: UNCST-2022-R011535
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Malaria drug and diagnostic resistance in refugee children in Uganda
REFNo: HS2164ES
1. Compare the prevalence of malaria parasitemia in refugee children arriving at Kyangwali and Adjumani reception centers and nearby non-refugee populations
2. Compare the prevalence of Pf mutations associated with resistance to key antimalarials between refugee and non-refugee populations
3. Compare the prevalence of Pf HRP-2 gene deletions that mediate diagnostic resistance between refugee and non-refugee populations
4. Compare Pf malaria parasites genetic relatedness between parasites isolated from newly arriving refugee children and those in refugees already in camps and in surrounding populations
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Uganda |
2022-05-18 17:05:19 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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