Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
 Ring vaccination trial to evaluate the efficacy and safety of Sudan ebolavirus vaccines in Uganda
REFNo: HS2574ES

Probable SUVD and death from confirmed SUVD ,main secondary objective is to assess the safety of the vaccine by monitoring weekly for 21 days any adverse reactions to vaccination and any other serious adverse events,The primary analysis will be of laboratory-confirmed SUVD (from samples taken either while living, or within 48 hours of death),
 Uganda 2022-11-23 15:04:05 2025-11-23 Medical and Health Sciences Clinical Trial Non-degree Award
David Mukunya
ID: UNCST-2022-R010707
 Cerebral Oximetry, Metabolism and Perfusion for Prognosis And Management of Asphyxiated Neonates (COMPPAMAN) in eastern Uganda: a pilot study
REFNo: HS2551ES

1. To demonstrate the feasibility of monitoring cerebral tissue oxygenation (SO2), cerebral blow flow (CBF) and cerebral oxygen metabolism (CMRO2) among asphyxiated neonates and preterm infants in Jinja Regional Referral Hospital (Jinja RRH).
2. To determine evolution of post-natal cerebral hemodynamics and oxygen metabolism in asphyxiated and preterm infants in the first week of life. Specifically, we will
a. Perform several (daily) NIRS measurements over days on asphyxiated and preterm infants and up to two measurements on term newborns without evidence brain injury.
b. Compare these results in the first week of life with different etiologies of brain injury (hypoxia vs IVH) and controls.
c. Correlate NIRS results with the severity of brain insults determined by ultrasound.
H2.1 Asphyxiated neonates and preterm infants have lower Day 1 CBF and CMRO2 than controls.
H2.2 The decrease in CBF and CMRO2 is in proportion to the severity of brain injury.
3. To determine the predictive values of SO2, CBF and CMRO2 in neonatal mortality in the first week of life.
Gather data as in Aim 2.
H3.1 Cerebral hemodynamics and metabolism in the first week of life are sensitive biomarkers for mortality prediction.
H3.2 Changes in CBF and CMRO2 with age will add to the predictive value of mortality model at one week of life.

 Uganda 2022-11-23 12:51:56 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Muteesasira
ID:
Predicting Research Productivity of Academic Staff with PhDs in Universities in Uganda Using Bean's Model
REFNo: SS1521ES

To examine whether the individual variables in Bean’s model mediate the relationship between organisational variables and individual research productivity.,To examine whether organisational variables in Bean’s model predict individual variables.,To examine whether individual variables in Bean’s model predict individual research productivity.,To examine whether organisational variables in Bean’s model predict individual research productivity.,To examine whether Bean’s (1982) model can be used to predict research productivity of a member of academic staff with a PhD in a university in Uganda. ,
 Uganda 2022-11-23 12:50:38 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
PROSSY NANTALE NABATTE
ID:
CHARACTERIZATION OF HUMAN PAPILLOMAVIRUS GENOTYPES AND THEIR CORRELATES AMONG WOMEN LIVING WITH HIV ATTENDING ANTIRETROVIRAL THERAPY CLINIC IN MUKONO, UGANDA
REFNo: HS2550ES

To assess how medical history predisposes women living with HIV to Human papillomavirus genotypes in Mukono.,To establish how sexual practices predisposes women living with HIV to Human papillomavirus genotypes in Mukono.,To identify how socio-demographic factors predispose women living with HIV to Human papillomavirus genotypes in Mukono.,To describe the characteristics of Human papillomavirus genotypes among a cohort of WLHIV attending antiretroviral therapy clinic in Mukono, Uganda.,To explore the types and occurrence of HPV infection by genotyping Human papillomavirus among a cohort of WLHIV attending antiretroviral therapy clinic in Mukono, Uganda. ,
 Uganda 2022-11-23 12:47:55 2025-11-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 Final evaluation of Our Rights, Our Lives, Our Future (O3) Programme
REFNo: SS1515ES

2. Assess progress against targets set at baseline, validate, and populate the results framework.,4. Provide conclusions and actionable recommendations that can shape future programming and implementation by UNESCO of initiatives to advance education, health and wellbeing of AYP.,3. Identify opportunities, challenges, good practices, and lessons that will be useful for strengthening and enhancing the design and implementation of the next phase of the programme.,1. Ascertain the effectiveness (results/impact), efficiency, and sustainability of the O3Programme,The overall goal of this final evaluation is to provide UNESCO with a systematic assessment of the full implementation period of the O3 Programme (2018-2022) across all 33 countries. This assessment will analyse both expected and unexpected results and how these were achieved; capture challenges faced and measures taken to adapt and respond to these challenges; and extract good practices and lessons learned.,
 Uganda 2022-11-23 12:46:32 2025-11-23 Social Science and Humanities Non-degree Award
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