Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Isaac Ssewanyana
ID: UNCST-2020-R014336
Performance Evaluation of the Alinity m HIV-1 Assay using DBS
REFNo: HS2595ES

• To describe the operational characteristics and ease of use of the assays and their suitability for use in countries with limited infrastructure. ,• To assess the assay’s agreement with cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including: o Quantitative assessment of bias, limits of agreement and correlation, o Misclassification above or below the clinical threshold;,The overall objective of the performance evaluation is to evaluate the performance and operational characteristics of Alinity m HIV-1 Assay (using DBS) intended for the quantification of HIV viral load in HIV-infected individuals.,
Uganda 2022-12-12 16:06:22 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET  NAKIGANDA
ID:
Private Sector Malaria Vector Control Scoping in Uganda: A Land Scape Analysis
REFNo: SS1512ES

To understand the public (consumers) perspectives and practices in accessing vector control commodities from the private sector, specifically (enter commodities),3. To identify the capacity and technical challenges that affect the quality of products and services of private sector vector control ,2. To map out the private sector supply chain systems of vector control products from importation to consumption in Uganda.,1. To understand the current regulations governing the quality and product range of imported and locally manufactured vector control commodities,To identify immediate and core gaps in the policies, access, supply, and use of malaria vector control interventions in the private sector so that the NMCD can channel focal interventions to increase access to quality vector control interventions in the private sector. ,
Uganda 2022-12-12 16:00:29 2025-12-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
KENNETH MUGABE
ID: UNCST-2022-R010732
Using lactate testing to improve maternal sepsis identification: a multi-country test accuracy study: LACTate in mATernal sEpsis
REFNo: HS2589ES

VI. Conduct a validation study of an alternative reference standard in which the SOFA score is modified to incorporate maternity specific ranges for creatinine and platelet concentration.,V. Exploratory analysis will examine the effect of adjusting the threshold values for both vital sign and lactate assessment on the sensitivity and specificity of the index tests.,IV. To explore if the test accuracy of lactate in addition to maternal vital sign monitoring alone varies by the pre-specified subgroups of pregnancy status (pregnant or post-delivery (including abortion or miscarriage)) and recruitment country.,III. To explore if baseline venous lactate, in addition to vital sign measurements, improves prediction of severe morbidity and mortality from infection.,II. To assess short-term predictive value of lactate testing, by comparing the baseline index test with 24-hour reference standard, in those without sepsis at baseline.,I. Immediate diagnostic value of lactate testing by comparing the baseline index test with baseline reference standard.,Determine the diagnostic accuracy of maternal venous lactate measurement in addition to maternal vital sign thresholds, in maternal sepsis in low-resource health facility settings in Malawi, Uganda and Pakistan.,
Uganda 2022-12-12 15:55:39 2025-12-12 Medical and Health Sciences Clinical Trial Non-degree Award
Amrei von Braun
ID:
RAPID SURVEILLANCE OF MOLECULAR MARKERS FOR ARTEMISININ RESISTANCE
REFNo: HS2546ES

To describe the type and prevalence of Plasmodium falciparum mutations conferring artemisinin resistance
Germany 2022-12-12 15:42:25 2025-12-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BEATRICE KATUSIIME
ID:
UNDERSTANDING THE COMMUNITY’S AND RESEARCH PARTICIPANTS’ PERCEPTIONS AND KNOWLEDGE OF VULNERABILITY IN RESEARCH: A QUALITATIVE STUDY IN UGANDA
REFNo: SS1495ES

3. To examine the determinants of vulnerability in health research conducted in Mbarara city,2. To explore the perception of research participants regarding vulnerability in health research in Mbarara city,1. To assess the community’s understanding of vulnerability in health research in Mbarara city,To describe community and research participants’ perceptions and knowledge of vulnerability in health research in Mbarara city,
Uganda 2022-12-12 15:32:51 2025-12-12 Social Science and Humanities Non-Clinical Trial Degree Award
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