Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Josephine Najjuma Nambi
ID: UNCST-2021-R013717
 Developing and testing a simulation-based intervention to improve stroke nursing care in Mbarara Regional Referral Hospital
REFNo: HS3535ES

6. Pilot test the simulation-based nursing intervention for feasibility, acceptability, functionality, quality of life, and preliminary health outcomes among stroke patients at MRRH. ,5. Develop a simulation-based stroke training packet/intervention for nurses to improve stroke care and management at Mbarara Regional Referral Hospital,4. Explore the barriers and facilitators for stroke management, and training among health care professionals at Mbarara Regional Referral Hospital ,The general objective of the study is to develop and pilot a simulation-based stroke intervention to improve stroke management at MRRH ,
 Uganda 2024-05-07 13:49:58 2027-05-07 Medical and Health Sciences Clinical Trial Degree Award
David Guwatudde
ID: UNCST-2021-R008522
 Research network for design and evaluation of adolescent health interventions and policies in Sub-Saharan Africa (DASH)
REFNo: HS4116ES

The overarching and long-term goal for the DASH research activities is to boost adolescent health in SAA through rigorous population-based surveillance, intervention and policy research in seven SSA countries including Burkina Faso, Ethiopia, Ghana, Nigeria, South Africa, Tanzania and Uganda (henceforth referred to as the ‘African DASH partner countries’). The key functions to address these objectives are to combine the efficient collection and use of important adolescent health data, and the employment of robust quantitative and qualitative methods of data collection and evaluation with local domain-specific expert and stakeholder knowledge on the health domains nutrition & physical activity, sexual & reproductive health, and mental health & violence (henceforth referred to as the ‘DASH health domains’).,To examine and assess transportability of DASH interventions and population-level policies (Transportability), in order to context relate to adolescent and young adult health, with the aim to understand how this context moderates the impact of interventions and policies; subsequently we will aim to transport the evidence on impact, generated within DASH, to other contexts in SSA,To evaluate population-level policies (Policy evaluation) with the aim to prioritize and select multiple population-level policies, related to the DASH health domains, which likely affect the health of adolescents and young adults, and to subsequently evaluate and understand the impact and mechanisms of these policies in Ghana, South Africa and Tanzania,To evaluate the impact of the DASH interventions (Intervention evaluation), their impact and performance,To co-design DASH interventions (Co-Design) with the aim to gain an understanding of local intervention needs and will co-design and pilot test interventions to improve nutrition & physical activity in South Africa, sexual & reproductive health in Uganda, and mental health & violence in Tanzania; these designed interventions will then be locally adapted in each African DASH partner country,To implement and test multiple light-touch interventions, which are relatively non-invasive, resource non-intensive interventions that aim to influence intentions, motivations and behaviors related to the three DASH health domains,To conduct surveillance of health and health-related risks (Surveillance) in order to determine trends and changes in adolescent and youth health, well-being and behaviors, particularly related to the three DASH health domains.,
 Uganda 2024-05-07 12:44:23 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
 Improving access to Asthma Care among Children and Adolescents in Uganda
REFNo: HS4136ES

To assess the feasibility, acceptability, and effectiveness of routine screening for asthma symptoms, healthcare worker needs-directed training and mentorship and asthma education in improving diagnosis and management of children and adolescents with asthma in Uganda. Specific objectives The study is divided into 4 sub-studies, and each of them has specific objectives as outlined below. Sub-study 1: Routine screening for asthma symptoms Objectives 1. To evaluate the clinical and cost-effectiveness of routine screening for asthma symptoms among children and adolescents with respiratory illnesses in identification of patients with undiagnosed asthma 2. To assess the feasibility and acceptability of routine screening for asthma symptoms among children and adolescents with respiratory illnesses. Sub-study 2: Healthcare workers’ needs-directed training and mentorship Objectives 1. To evaluate the clinical and cost-effectiveness of needs-directed healthcare workers’ training and mentorship in improving asthma outcomes in children and adolescents. 2. To assess the feasibility and acceptability of implementing a needs-directed healthcare workers’ training and mentorship intervention for improving asthma outcomes in children and adolescents. Sub-study 3: Community Health Worker-led asthma education Objectives 1. To assess the clinical and cost-effectiveness of community health worker-led asthma education in improving asthma outcomes among children and adolescents. 2. To assess the feasibility and acceptability of community health worker-led asthma education among children and adolescents, and their caregivers. Sub-study 4: Psychosocial challenges of asthma Objective 1. To explore the psychosocial challenges faced by children and adolescents with asthma, and their caregivers.
Uganda 2024-05-07 12:43:04 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ounyesiga Living
ID: UNCST-2024-R005177
 MODELING, SIMULATION AND OPTIMIZATION OF SOLAR POWER GENERATION AND TRANSMISSION IN UGANDA
REFNo: SIR322ES

Objectives of the Study
General Objective. The main objective of the study is to model, simulate and optimize solar power generation and transmission in Uganda.
Specific Objectives
The specific objectives are as follows:
(i) To modify the traditional power loss objective function in order to minimize electric power losses on Ugandan electricity transmission lines
(ii) To develop a mathematical models for coupled and uncoupled transmission lines, which can simulate lossy and lossless transmission parameters of current, voltage and temperature.
(iii) To formulate a differential equation for solar power generation and multiple empirical models for improving Photo Voltaic (PV) system design and operations.

 Uganda 2024-05-07 12:37:34 2027-05-07 Engineering and Technology Non-Clinical Trial Degree Award
ANTHONY ONONO JAMES
ID:
FACTORS ASSOCIATED WITH HEALTH CARE WASTE MANAGEMENT PRACTICES AMONG HEALTHCARE WORKERS IN GULU CITY
REFNo: HS4009ES

3. To identify healthcare system factors associated with effective healthcare management practices among healthcare workers in Gulu city, located in Northern Uganda.,2. To assess individual factors associated with the management of healthcare waste by healthcare staff in Gulu city, located in the northern region of Uganda.,1. To assess the healthcare waste management practices among healthcare workers in Northern Uganda\'s Gulu city.,To assess factors associated with healthcare waste management practices among health care workers in Gulu city. ,
 Uganda 2024-05-07 12:36:35 2027-05-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Ntirandekura  Moses
ID: UNCST-2023-R005665
 GOOD GOVERNANCE AND WOMEN ECONOMIC EMPOWERMENT IN SELECTED DISTRICTS OF SOUTH WESTERN UGANDA: A STUDY OF UGANDA WOMEN ENTREPRENEURSHIP PROGRAMME (UWEP)
REFNo: SS2612ES

i. To establish the effect of accountability in implementation of UWEP on women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. ii. To examine the extent to which transparency in implementation of UWEP affects women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. iii. To determine the influence of participation in implementation of UWEP on women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. iv. To identify how equitability and inclusiveness in implementation of UWEP affect women economic empowerment in Kisoro and Kabale Districts of South Western Uganda. v. To determine the relationship between gender regulatory policies and women economic empowerment in Kisoro and Kabale Districts of South Western Uganda.
Uganda 2024-05-07 12:35:04 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Comfort
ID: UNCST-2022-R011501
 Social networks and their role in early initiation of antenatal care by HIV serostatus in Uganda
REFNo: HS4061ES

Through a quantitative survey data collection using a prospective cohort design, this study aims to: 1) Understand whether there exists an association between social network characteristics and early ANC initiation; 2) Explore whether visualizing social network characteristics differentially affects care-seeking intentions at delivery; 3) Characterize the social network characteristics of pregnant women seeking ANC and assess whether differences exist by serostatus; 4) Assess whether network characteristics are differentially associated with early ANC initiation depending on serostatus, with similar analyses for other perinatal care indicators (e.g., facility-based delivery, post-partum care and infant HIV testing if applicable)
USA 2024-05-07 12:25:25 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Barnabas Atwiine
ID: UNCST-2022-R010629
 Assessing Implementation and Effectiveness of a Cash Incentive Family Support Intervention to Reduce Treatment Abandonment and Increase Survival among Children with Cancer in Sub-Saharan Africa
REFNo: HS3897ES

1. To assess the effectiveness of the intervention on end-of-treatment survival without evidence of disease.
2. To assess the proportion of eligible caregivers that access all planned mobile money instalments throughout the course of treatment.
3. To assess the cost-effectiveness of the intervention within the health system of participating
countries by WHO-CHOICE standards; defined as a cost less than three times the annual per
capita income per disability adjusted life year (DALY) averted.
4. To describe the views of stakeholders (policy makers, health providers and clients) on the acceptability and feasibility of the intervention.
Uganda 2024-05-07 11:43:52 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simran Prasad
ID:
Male reproductive skew, female codominance and mate choice, and inbreeding avoidance in wild vervet monkeys (Chlorocebus pygerythrus).
REFNo: NS801ES

The purpose of this project is to investigate the relationship between male dominance rank and mating and paternity success, degree of reproductive skew, female codominance and mate choice, and the direction of inbreeding avoidance in a population of vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo, Uganda.
Canada 2024-05-07 11:24:53 2027-05-07 Natural Sciences Non-Clinical Trial Degree Award
MUWANGUZI MOSES
ID: UNCST-2021-R013695
 Depression among pregnant teenagers receiving antenatal care from health facilities in Mbarara city, Southwestern Uganda
REFNo: HS3913ES

To determine the factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,To determine the prevalence of depression among pregnant teenagers in Mbarara city, southwestern Uganda. ,To determine the prevalence and factors associated with depression among pregnant teenagers in Mbarara city, southwestern Uganda.,
 Uganda 2024-05-07 11:07:54 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Samuel  Obakiro Baker
ID: UNCST-2019-R000065
 FORMULATION AND PRECLINICAL EVALUATION OF HERBAL PRODUCTS FOR MANAGEMENT OF DIABETES MELLITUS AND ITS COMORBIDITIES IN UGANDA
REFNo: HS4127ES

To analyze the phytochemical and pharmaceutical properties of the formulated herbal products,To assess the antidiabetic activity and toxicity of the formulated herbal products for the management of DM using in vitro and in vivo models,2. To formulate herbal products for management of DM ,1. To prioritize medicinal plants for formulation of herbal products for management of diabetes mellitus (DM),To develop standard herbal products for management of DM with proven preclinical evidence of efficacy and safety ,
 Uganda 2024-05-07 11:04:09 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Mbabazi Byakwaga
ID:
KIZINO DANCE-MUSICKING: NEGOTIATING ETHNIC IDENTITY AMONG BAKIGA IMMIGRANTS IN RUBIRIZI DISTRICT, WESTERN UGANDA
REFNo: SS2261ES

To examine how kizino dance-musicking is used to negotiate kikiga ethnic identity in Rubirizi District ,To explore the continuity and change in the nature and context of kizino dance-musicking among the Bakiga in Kabale and Rubirizi Districts,To examine the nature of the ethnic identity of the Bakiga in Kabale and Rubirizi Districts,To examine how Bakiga immigrants negotiate their ethnic identity in Rubirizi District,
 Uganda 2024-05-07 10:45:55 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
DORAH NAMPIJJA
ID: UNCST-2022-R009694
 Acute Rheumatic Fever Biomaker Project; Preventing Rheumatic Injury Biomarker Alliance: the Leducq PRIMA Network
REFNo: HS4091ES

iv. To design and validate a point of care diagnostic test for early ARF diagnosis,iii. To perform unbiased biomarker screens for ARF among children with ARF and to apply rigorous statistical analyses to identify biomarker(s) with high predictive power for ARF diagnosis ,ii. To conduct a case control study to understand the factors associated with ARF and disease progression among children aged 5-18 years,i. To create an Acute Rheumatic Fever registry and profile the phenotype among children with ARF aged 5-18 years,To identify accurate molecular biomarker(s) for ARF, and design a point of care diagnostic tool for early ARF diagnosis,
 Uganda 2024-05-02 12:45:10 2027-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Magumba Nakagolo
ID:
The Influence of the Adoption of the E-tax System on Tax Compliance in Uganda.
REFNo: SS2552ES

To establish ways in which online tax systems can be maximally utilised to improve tax compliance in Uganda.,To establish the association between the adoption of eTax and taxpayer demographics, and how that association affects tax compliance in Uganda.,To establish the association between the adoption of eTax and tax administration efficiency, and how that association affects tax compliance in Uganda. ,To establish the relationship between the adoption of eTax and the different elements of tax compliance (registration, filing and payment) in Uganda.,To determine the influence of the adoption of the eTax system on tax compliance in Uganda. ,
 Uganda 2024-05-02 12:43:39 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
Mathieu Chabry Eric
ID: UNCST-2024-R004404
 Toxoplasma in chimpanzees (Pilot study)
REFNo: NS789ES

This study is a pilot study which aims to look at the behavioral effects of the parasite Toxoplasma gondii in two populations of wild chimpanzees at the Budongo conservation field station. the project aims to understand correlations between infection and behaviors, to see if there are differences between infected and non infected individuals. The objectives of the research are the following:
- To see whether infection by the parasite toxoplasma gondii changes behavior of infected chimpaanzees by comparing infected and uninfected individuals (by comparing infected and non infected individuals)
- Establish infection status in a population of wild chimpanzees by collecting urine and check which individuals are infected and those which aren't (collecting urine non invasively)
- To see whether infection influences risky behaviors in wild chimpanzees (aggression towards higher ranking chimpanzees, foraging close to the borders of the territory)
- Determine if infection influences reaction to unfamiliar stimul (false fruits, remoted controlled animals maybe)
- Establish trends in behavior and compare infected and non-infected individuals
- Collect behavioral data in the purpose of establishing new studies possibilities
 Switzerland 2024-05-02 12:42:07 2027-05-02 Natural Sciences Non-Clinical Trial Degree Award
Charles Lwanga Tumuhe
ID:
Exploring perspectives of agroecology network organizations regarding their role in climate change adaptation in Uganda
REFNo: A409ES

To explore the understanding of agroecological initiatives made by the various network member organizations and their partners in their effort to help communities adapt to climate change.
To establish the perceived nature of the relationships and connections between agroecology as a movement and Climate Change adaptation

To establish the perceived benefits to network members from joint agroecological climate adaptation initiatives.

Uganda 2024-05-02 12:41:06 2027-05-02 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Kinera
ID: UNCST-2022-R009689
 POST TB LUNG DISEASE AMONG CHILDREN IN UGANDA, A CROSS SECTIONAL STUDY
REFNo: HS3961ES

3. To assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital.,2. To determine the correlation between clinical characteristics and lung function among children previously treated for PTB at Mulago National Referral Hospital.,1. To describe the clinical characteristics of PTLD among children previously treated for PTB at Mulago National Referral Hospital.,To describe the clinical characteristics of PTLD, assess the correlation between the clinical characteristics and lung function and to assess the health-related quality of life of children and caregivers of children who were previously treated for PTB at Mulago National Referral Hospital. ,
 Uganda 2024-05-02 12:39:55 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
 Simulation-based training for mesh inguinal hernia repair under local anaesthesia - a randomized trial
REFNo: HS4058ES

Assess the learning curve of mesh inguinal hernia repair for novice learners and how it is affected by simulation based training prior to supervised surgery on patients.
Sweden 2024-05-02 12:38:06 2027-05-02 Medical and Health Sciences Clinical Trial Degree Award
Daniel Zaake
ID: UNCST-2019-R000923
 Infertility in Uganda: The Burden, quality of Life, lived experiences of individuals Diagnosed with infertility and Availability of services for Diagnosis and treatment of infertility.
REFNo: HS3901ES

1. To determine the prevalence and determinants of infertility in Uganda.
2. To evaluate the quality of life among individuals with infertility seeking fertility treatment in Kawempe National Referal Hospital (KNRH) and St Francis Hospital Nsambya(SFHN) in Kampala
3. To explore the lived experiences of couples and individuals diagnosed with infertility at KNRH and SFHN in Kampala
4. To assess the availability of services for diagnosis and treatment of infertility in Uganda.
Uganda 2024-05-02 12:37:00 2027-05-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Waiswa
ID:
The enablers and barriers to remote work for persons with disabilities in Greater Kampala Metropolitan Area, Uganda
REFNo: SS2394ES

To create a deeper understanding of the enablers and barriers to remote work, including impacts on employability, for PWDs in Greater Kampala Metropolitan Area, principally to inform practice and policy in the design of interventions for disability-inclusive employment in Uganda as the country fast-tracks the UN Convention on the Rights of People with Disabilities, Sustainable Development Goal 10, and Vision 2040.,
 Uganda 2024-05-02 12:20:40 2027-05-02 Social Science and Humanities Non-Clinical Trial Degree Award
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