Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
MARILYN BAKO ARUMADRI
ID: UNCST-2024-R002256
 IMPLEMENTATION OF THE UNITED NATIONS SECURITY COUNCIL RESOLUTION 1325 AND REPRESENTATION OF WOMEN IN LEADERSHIP POSITIONS IN SECURITY INSTITUTIONS IN UGANDA
REFNo: SS4324ES

3. Identify challenges perceived and related to women involvement in decision-making leadership positions in security institutions in Uganda.,2. Examine the impact of the implementation of UNSCR 1325 on women’s representation in the security institutions in Uganda; and,1. Examine the adoption and implementation of UNSCR 1325 in the security institutions in Uganda;,The broad aim of the study is to examine the implementation of UNSCR 1325 and representation of women in decision-making leadership positions in the security institutions of Uganda.,
 Uganda 2025-09-17 13:29:27 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
 PACO Heart Evaluation and Risk Tracking (PACO-HEART)
REFNo: HS5985ES

Main objective: 1. Determine whether women with HIV taking DTG during pregnancy are more likely to experience hypertension, have elevated cardiovascular disease risk factors, and demonstrate vascular dysfunction postpartum.

Sub-Objectives:
1. Prospectively assess postpartum cardiovascular disease risk factors in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
2. Assess vascular function in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
3. Quantify and compare biomarkers of cardiovascular disease in peripheral plasma in women with HIV on DTG versus women with HIV on efavirenz (EFV), women who took PrEP in pregnancy, and women without HIV participating in the PACO cohort.
4. Examine association between placenta pathological features (already measured in PACO cohort participants) and postpartum hypertension, vascular function, and biomarkers of cardiovascular disease


 Uganda 2025-09-17 13:26:00 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Kyohairwe Baketuraki
ID: UNCST-2024-R004001
 The Cost of Doing Politics: Gender Aspects of Political Violence
REFNo: SS3887ES

Aim/Overall objective: This project aims to better understand how gender shapes the scope, form, and consequences of political violence targeted at politicians, as well as to develop response strategies to reduce the problem.
RQ 1: How does gender shape the scope and form of political violence? What are the gendered dimensions of violence in political parties’ election campaigns and in the parliamentary arena?
RQ2: What are the gendered consequences of political violence on political representation in political party recruitment – and at parliamentary arenas?
RQ 3: What are the most effective and gender-sensitive responses to different forms of political violence in political party recruitment -and in the parliamentary sphere?
 Uganda 2025-09-17 13:24:26 2028-09-17 Social Science and Humanities Non-Clinical Trial Non-degree Award
NORBERT BYARUHANGA MUSISI
ID: UNCST-2024-R002079
 PREVALENCE AND FACTORS ASSOCIATED WITH ADVERSE PERINATAL OUTCOMES AMONG WOMEN WITH LATE ANTENATAL CARE BOOKING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5772ES

1. To determine the prevalence of adverse perinatal outcomes among women with late ANC booking at Mbarara regional referral hospital.
2. To determine the factors associated with adverse perinatal outcomes among women with late ANC booking at Mbarara regional referral hospital

 Uganda 2025-09-17 13:22:53 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Drug Optimisation for LMICs in Pregnant HIV mothers and their INfants: temporary switch to CAB/RPV long acting injections in postpartum period
REFNo: HS5982ES

To characterise drug exposure in breast milk, and drug transfer to infants through breastfeeding, as well as infant drug elimination. To characterise the elimination of CAB/RPV by describing PK profiles of IM CAB/RPV LA after last injection between 48 and 96 weeks. To establish strategies on how to safely re-establish oral ART after discontinuation of IM CAB/RPV LA at 48 weeks and switch back to daily oral ART. To explore early postpartum PK of CAB/RPV in maternal plasma and breastmilk. To demonstrate antiviral activity and impact on retention in HIV care of temporarily switching to CAB/RPV LA compared with continuation of daily oral ART over 48 weeks.,
 UK 2025-09-17 13:21:16 2028-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Acceptability and feasibility of long-acting injectable antiretroviral therapy (LAI-ART) as a bridging strategy for postpartum mothers living with HIV in South Africa and Uganda
REFNo: HS5944ES

3. To assess the feasibility of adopting LAI-ART into national ART programmes and healthcare facilities, identifying programmatic considerations for optimal LAI-ART deployment.,2. To explore patient acceptability of LAI-ART during breastfeeding and as a postpartum bridging strategy to enhance adherence.,1. To develop and validate a tool for identifying and supporting women at risk of poor ART adherence postpartum.,
 UK 2025-09-17 13:19:23 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
 Feasibility of clinical nuance implemented using value-based community financing for the management of diabetes and hypertension in primary health care in rural South-Western Uganda
REFNo: HS6153ES

3. To assess the willingness of the community to contribute to risk pooling towards clinically nuanced VBID,2. To understand the perspectives of health workers in implementing clinically nuanced care for diabetes and hypertension in the community.,1. To explore the community’s perception of clinically nuanced VBID in the prevention and management of diabetes and hypertension.,To investigate the potential of a community-level, value-based insurance design (VBID) in enhancing clinical management and prevention of hypertension and diabetes within primary health care,
 Uganda 2025-09-17 13:17:21 2028-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Mercy Wanyana Wendy
ID: UNCST-2025-R016999
 Barriers and facilitators to implementing one health approach for visceral leishmaniasis control in the Karamoja Region.
REFNo: HS6125ES

To examine barriers and facilitators to implementing one health approach for visceral leishmaniasis control in the Karamoja,2025.
 Uganda 2025-09-17 13:05:50 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lillian Mugisha
ID: UNCST-2025-R018187
 Impact of a Co-designed School-Based Intervention on 24-Hour Movement Behaviour and Selected Health Indicators Amongst Female Adolescents in Wakiso District, Uganda
REFNo: SS3966ES

1. Determine the level of adherence to 24-HMB guidelines among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda.
2. Explore the determinants of adherence to 24-HMB guidelines among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda.
3. Co-design a SBMB intervention with adolescent girls and teachers, targeted to enhance 24-HMB among adolescent girls aged 15-18 years in secondary schools in Wakiso District, Uganda.
4. Determine the association between accelerometer-measured 24-HMB and selected health indicators (CRF, BMI, WHtR, and BP) among adolescent girls aged 15-18 years in secondary schools in Wakiso District, Uganda.
5. Determine the impact of a co-designed SBMB intervention program on 24-HMB, and selected health indicators (CRF, BMI, WHtR and BP) among adolescent girls aged 15-18 years in mixed-boarding secondary schools in Wakiso district, Uganda

 Uganda 2025-09-17 13:03:31 2028-09-17 Social Science and Humanities Non-Clinical Trial Degree Award
Mugumya  Kabaja Lawrence Kabaja
ID: UNCST-2024-R002956
 Evaluating the effect of Caregiver DOTs on viral re-suppression among children in Kigezi region
REFNo: HS6505ES

1. To establish the viral re-suppression rates among children on the CAGDOTS strategy in Kigezi Region. 2. To find out the factors associated with viral load re-suppression among the CALHIV) in Kigezi region.
Uganda 2025-09-17 12:36:18 2028-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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