Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruno Sserunkuuma
ID:
PREVALENCE AND FACTORS ASSOCIATED WITH ADVERSE MATERNAL OUTCOMES OF SPINAL INDUCED HYPOTESION AMONG WOMEN UDERGOING CEASAREAN DELIVERIES AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS2562ES

General objective.
To determine the prevalence and factors associated with adverse maternal outcome of spinal induced hypotension among women undergoing caesarean deliveries at Mbarara Regional Referral Hospital
Specific objectives
1.To determine the prevalence of mothers that develop spinal induced hypotension undergoing caesarean deliveries at Mbarara Regional Referral Hospital.
2.To determine the factors associated with spinal induced hypotension among mothers undergoing caesarean deliveries at Mbarara Regional Referral Hospital
3.To describe the adverse maternal outcomes among women with spinal induced hypotension


Uganda 2023-02-07 11:14:38 2026-02-07 Medical and Health Sciences Non-Clinical Trial Degree Award
DIANA NABUKENYA KASOZI
ID:
TIME TO TREATMENT INITIATION AMONG PATIENTS TREATED FOR DR-TB IN UGANDA
REFNo: HS2653ES

1. To determine the socio-demographic factors associated with drug-resistant tuberculosis (DR-TB) treatment delay among DR-TB patients in order to achieve a successful or unsuccessful treatment outcome in Uganda.
2. To investigate what clinical factors associated with DR-TB treatment delay among DR-TB patients in order to attain a successful or unsuccessful treatment outcome in Uganda.
3. Describe the structural factors associated with DR-TB treatment delay among DR-TB patients in order to achieve a successful or unsuccessful treatment outcome in Uganda.
4. To estimate the mean and median time to DR-TB treatment from the time of DR-TB diagnosis for patients on DR-TB treatment in Uganda.

Uganda 2023-02-06 17:25:58 2026-02-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
The Impact of HIV on the Breast Cancer Tumor Microenvironment
REFNo: HS2651ES

Compare the molecular profile of breast cancer tissue and blood using targeted sequencing from HIV+ women and HIV- women to identify potential HIV-associated features driving increased tumor aggressiveness.,Assess if the presence, spatial distribution, and/or the cellular phenotype of immune cells in the breast TME are consistent with HIV- associated immune dysfunction in WLWH compared to HIV- women,Identify features of HIV-associated immune dysfunction in blood and tumor tissue from WLWH with breast cancer that could promote tumorigenesis and progression.,
Uganda 2023-02-06 17:24:00 2026-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shannon McMorrow
ID:
Photovoice assessment of integration, health, and healthcare experiences of urban Congolese refugee women in Kampala, Uganda
REFNo: HS2655ES

To generate in-depth, contextual evidence to inform policy and program improvements for Congolese refugee women in Kampala to prevent further marginaliation and negative health outcomes.
USA 2023-02-06 17:19:40 2026-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
A Phase 3, multicenter, randomized, double-blind, 24-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized participants with COVID-19
REFNo: HS2642ES

The main intent of the study is to evaluate the efficacy of S-217622 vs. placebo. The study will be conducted in the setting of the locally available standard-of-care COVID-19 treatment. High-risk and low-risk participants will be analyzed together for the primary analysis and separately for secondary analyses. The following primary, secondary, and exploratory objectives will be addressed in the modified intent-to-treat (mITT) population, except for the safety analyses, which will be analyzed in the Safety population, and pharmacokinetic (PK) analyses, which will be analyzed in the PK population.
Uganda 2023-02-06 17:17:04 2026-02-06 Medical and Health Sciences Clinical Trial Non-degree Award
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