Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Arthur  Mpimbaza
ID: UNCST-2022-R008866
A model health systems strengthening strategy to reduce malaria mortality in the Busoga sub-region, Uganda: a proof-of-concept trial
REFNo: HS3927ES

General Objective
To determine the viability of a model health system strengthening (HSS) strategy in improving the quality of malaria management services and empowering communities in Bunya East HSD, Mayuge district, Busoga sub-region.

2 Specific objectives
1. To determine the feasibility of implementing a model HSS strategy in improving the quality of malaria management services offered at facilities in Bunya East HSD.
2. To assess the acceptability of a model HSS strategy in improving the quality of malaria management services offered at facilities in Bunya East HSD.
3. To develop a process of engaging and empowering communities’ to take-up appropriate malaria health seeking behavior at a village in Bunya East HSD.
4. To assess the preliminary effectiveness of the model HSS strategy on outcomes related to appropriate malaria case management at facilities and the community in Bunya East HSD.


Uganda 2024-05-15 18:19:15 2027-05-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sunny Okoroafor C
ID:
ASSESSMENT OF PATIENT SAFETY PRACTICES IN UGANDA
REFNo: SS2596ES

To determine the status of the patient safety practices in Uganda.,
Nigeria 2024-05-14 9:17:02 2027-05-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Racheal Angom
ID: UNCST-2023-R007485
ELECTRONIC TREATMENT SCHEDULING AND PSYCHOSOCIAL INTERVENTIONS TO REDUCE TREATMENT ABANDONMENT AMONG CHILDREN AND ADOLESCENTS WITH CANCER IN UGANDA.
REFNo: HS3944ES

To develop a comprehensive psychosocial support program through collaboration among UCI, UCCF and other civil society organizations to decrease treatment abandonment. ,To determine factors that influence treatment abandonment for UCI patients,To determine parent/caregiver reasons for treatment abandonment ,To Create a tracking system for patient treatment appointments to identify initial missed treatment visits (risk for treatment abandonment) and actual treatment abandonment using a time-sensitive electronic system [Research Electronic Data Capture (REDCap)] , To Create a tracking system for patient treatment appointments to identify initial missed treatment visits (risk for treatment abandonment) and develop a comprehensive psychosocial support program through collaboration among UCI, UCCF and other civil society organizations to decrease treatment abandonment. actual treatment abandonment using a time-sensitive electronic system [Research Electronic Data Capture (REDCap)] and,
Uganda 2024-05-14 9:12:26 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
Clinical validation of novel microfluidic-based technologies for detection of Lower Respiratory Tract Infections (HOLICARE Trial)
REFNo: HS3718ES

1. To determine the sensitivity and specificity of the Multi- Lateral Flow Test (LFT) using nasopharyngeal swab with visual detection and using a mobile phone as a reader.
To determine the sensitivity and specificity of the Multi- Lateral Flow Test (LFT) using nasopharyngeal swab with visual detection and using a mobile phone as a reader.
To validate the clinical performance, sensitivity and specificity of a Point of Care (POC) platform that performs pathogen detection (bacteria, fungi) using microfluidic- Loop mediated isothermal amplification (LAMP) isothermal amplification and quantification of host-response biomarkers using a bead-based immunoassay, by comparing its results to those of reference standard methods:benchtop Polymerase Chain Reaction (PCR) and Enzyme Linked Immunosorbent Assay (ELISA), respectively.
To assess whether the POC-Instrument can be inserted in the patient management procedure to assist clinical decision-making.
(2) To assess the hands-on usability of the POC-Instrument and receive feedback by end-users for future implementation in clinical practice.

Uganda 2024-05-14 9:08:56 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jeremiah Alisengawa
ID: UNCST-2022-R009718
MANAGEMENT LEVEL SUPPORT SYSTEMS AND STRATEGIC PLAN IMPLEMENTATION IN CHARTERED PRIVATE UNIVERSITIES IN UGANDA. A SURVEY ON NDEJJE AND NKUMBA UNIVERSITIES.
REFNo: SS2199ES

4. To investigate the self-involvement role of action-level management in the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,3. To examine the operationalization role of operations-level management during the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,2. To assess the coordination role of middle-level management in the implementation of strategic plans of Ndejje and Nkumba Universities in Uganda.,To examine the support role of top-level management in the implementation of strategies of Ndejje and Nkumba Universities in Uganda.,
Uganda 2024-05-14 9:05:50 2027-05-14 Social Science and Humanities Non-Clinical Trial Degree Award
Jamon Van Den Hoek
ID: UNCST-2023-R006549
Multi-sensor Mapping of Refugee Agricultural Land-Cover/Land-Use Change Hotspots in Uganda
REFNo: A414ES

Map changes in crop area and type in refugee-hosting districts with multi-sensor satellite time series analysis and transfer learning.
USA 2024-05-14 9:03:35 2027-05-14 Agricultural Sciences Non-Clinical Trial Non-degree Award
Ria  Kapoor
ID:
From Migrant to Citizen to Refugee: a Global History of the 1972 Ugandan Asian Expulsion
REFNo: SS2625ES

I will assess the impact of a connected, sovereign Afro-Asian world on the international order and attendant structures. Within the long-term aim to understand citizenship, diaspora, and immigration my immediate focus is the 1972 Ugandan Asian Expulsion. From Migrant to Citizen to Refugee traces how a transformation of citizenship across the British Empire took place, with the expulsion of the Ugandan Asians by Idi Amin in 1972 and their resettlement in Britain, Canada, and India following the decolonisation of East Africa. It emphasises this transformation of citizenship as part of a worldwide process of decolonisation.

The project also explores how these changes to citizenship also changed UN-led practices. I explore how humanitarian assistance was provided, with the international community becoming complicit in the social reconfigurations enacted by postcolonial states. Deemed ‘refugees’ in some cases and ‘citizens’ in places like India, Canada and the UK, Uganda’s Asians’ citizenship in other areas of the former British Empire became fluid in the discourse of immigration and belonging in the 1970s as a result of postcolonial citizenship itself being transformed.


India 2024-05-14 9:02:46 2027-05-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
Perceptions and acceptance of malaria vaccine among caregivers of children admitted with severe malaria in a highly endemic area in Uganda; a mixed methods study
REFNo: HS4059ES

To explore the perceptions of caregivers of children admitted with severe malaria in Tororo General Hospital about malaria vaccine,To investigate the factors associated with the acceptability of malaria vaccine among caregivers of children admitted with severe malaria in Tororo General Hospital in Uganda,To determine the proportion of caregivers of children admitted with severe malaria in Tororo General Hospital who will accept the malaria vaccine,To assess the perceptions and acceptance of malaria vaccine and associated factors among caregivers of children admitted with severe malaria in Tororo General Hospital. ,
Uganda 2024-05-14 9:01:46 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
A multi-component mHealth intervention ‘eCap-CoDe’ consisting of training, data capture and feedback tailored for improved community-based dementia care in rural Uganda: the barriers, ideating, development process
REFNo: HS4064ES

To ideate and develop a prototype for a multi-component mHealth application consisting of training, data capture and feedback to the PHC providers to improve community-based dementia care,To identify the barriers and facilitators faced by the PHC providers in rural Uganda as it relates to training, data capture and feedback on dementia assessment and management,To explore the barriers faced by the PHC providers in rural Uganda as it relates to training, data capture and feedback on dementia assessment and management, and co-design a multi-component mHealth intervention to improve community-based dementia care,
Uganda 2024-05-14 9:00:15 2027-05-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Melody Niwamanya
ID: UNCST-2019-R000928
Mid-term Evaluation Survey for Second Education Response Plan [ERP II] for refugees and host communities. Ref No: MUREC- 2024-366
REFNo: SS2610ES

To identify and document key areas of learning for partners and stakeholders engaged in the implementation of ERP II.,Examine the extent to which interventions are delivered or are likely to deliver results in an inclusive, economic, and timely manner.,To assess the relevance and coherence of planned interventions specifically examine the extent to which interventions implemented address the needs and priorities of targeted beneficiaries including complementarity of interventions, harmonization, and coordination of implementation,To assess the effectiveness of the implementation of interventions planned in ERP II by partners and stakeholders. Particularly assess progress towards implementation of planned activities and delivery of outputs aligned to ERP II objectives.,
2024-05-07 14:22:46 2027-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
LYDIA NAMIREMBE
ID: UNCST-2023-R006332
PREDICTORS OF HIV STATUS DISCLOURE TO INTIMATE PARTNERS AMONG HIV POSITIVE FEMALES AGED 20-49. A CROSS SECTIONAL STUDY IN BUIKWE DISTRICT, UGANDA.
REFNo: SS2570ES

iii. To explore the factors related to healthcare services that influence the inclination to disclose HIV test results to intimate partners among HIV-positive females aged 20-49 in Buikwe district.,ii. To identify the psychological factors that influence the inclination to disclose HIV test results to intimate partners among HIV-positive females aged 20-49 in Buikwe district.,i. To assess the socio-economic factors that impact the inclination to disclose HIV test results to intimate partners among HIV-positive females aged 20-49 in Buikwe district.,The primary goal of this study is to examine the factors that play a role in determining the willingness to reveal HIV test results to intimate partners among females aged 20-49 who are living with HIV in the Buikwe district.,
Uganda 2024-05-07 14:19:27 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Hadijah Nansamba
ID:
INSTITUTIONALIZATION OF INFORMAL JUSTICE SYSTEM AND MITIGATION OF GENDER-BASED VIOLENCE IN BUNDIBUJYO DISTRICT IN WESTERN UGANDA
REFNo: SS2580ES

Purpose of the Study
To investigate the effect of institutionalization of informal justice systems towards Gender-Based Violence mitigation in Bundibugyo District in western Uganda

Specific Objectives
i. To assess the effect of institutionalization of traditional cultural courts towards mitigation of Gender-Based Violence in Bundibugyo District.
ii. To examine the effect of institutionalization of semi-formal local council courts towards mitigation of Gender-Based Violence in Bundibugyo District.
iii. To examine the effect of institutionalization of alternative community-based systems towards mitigation of Gender-Based Violence in Bundibugyo District.
iv. To explore the stakeholder perception about the effectiveness of institutionalization of the informal justice system towards mitigation of gender-based violence in Bundibujyo District

Hypotheses
i. There is no statistically significant effect of institutionalization of traditional cultural courts towards mitigation of Gender-Based Violence in Bundibugyo District
ii. There is no statistically significant effect of institutionalization of semi-formal local council courts towards mitigation of Gender-Based Violence in Bundibugyo District
iii. There is no statistically significant effect of institutionalization of alternative community-based systems towards mitigation of Gender-Based Violence in Bundibugyo District

Research Question
i. How do stakeholders perceive the effectiveness of the institutionalization of the informal justice system toward the mitigation of gender-based violence in Bundibugyo District?

Uganda 2024-05-07 14:11:05 2027-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Multi-level intervention for intersectional stigma reduction to improve HIV outcomes for sex workers
REFNo: HS4129ES

Aim 1: Adapt the multilevel PRISM ISD-reduction intervention to address ISD
for SW in Uganda.
Aim 2: Conduct a pilot hybrid type 1 effectiveness-implementation trial to test
the preliminary effectiveness of the adapted multilevel Ssinga Nze ISD-
reduction intervention on (a) PrEP adherence or (b) viral suppression
among SW using a status-neutral approach.
Aim 3: Evaluate implementation of Ssinga Nze using qualitative methods.
Uganda 2024-05-07 14:09:03 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizabeth Nyboer Ann
ID: UNCST-2023-R005929
Using population genetics to inform sustainable aquaculture governance in Lake Victoria, Uganda
REFNo: NS798ES

Specific aims are to: (i) characterize the genetic profiles of Nile Tilapia (Oreochromis niloticus) in Ugandan fish farms, and (ii) investigate levels of admixture and introgressive hybridization among farmed and wild O. niloticus and endemic Oreochromis species.
Canada 2024-05-07 14:07:15 2027-05-07 Natural Sciences Non-Clinical Trial Non-degree Award
Jenny Löfgren
ID: UNCST-2024-R005428
Simulation based training for hernia mesh repair for novice learners – a randomized trial
REFNo: HS4176ES

b) Assess the student’s perception of the respective training methods.,a) Compare the learning outcomes regarding the ability to carry out an anterior groin hernia mesh repair on a 3D model for learners who participate in simulation-based training under supervision versus those who practice in simulation-based training without supervision.,
Sweden 2024-05-07 14:06:01 2027-05-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Katherine Hill Jane
ID: UNCST-2023-R005519
MITICare: Multimorbidity in Tuberculosis and Its Impact on Patient Care
REFNo: HS3888ES

Retrospective Cohort Objectives: Primary Objective: To describe the prevalence and patterns of multimorbidity in people with TB-HIV in Kampala. Secondary Objectives: To evaluate how prevalence and patterns of multimorbidity compare between people with TB-HIV and PLWHIV who do not develop TB within the cohort timeframe. To determine the effect of multimorbidity on end of TB treatment outcomes. Cross-sectional Study Nested Within Prospective Cohort Study Objectives: Primary Objective: To describe the prevalence of multimorbidity in patients at the start of treatment for TB in Kampala. Secondary Objectives: To determine the effect of multimorbidity on clinical characteristics of TB at the start of treatment. To determine the effect of multimorbidity on TB treatment outcomes. Exploratory Objective: To determine the effect of multimorbidity on progress through TB care.
UK 2024-05-07 14:04:46 2027-05-07 Medical and Health Sciences Non-Clinical Trial Degree Award
PAUL LWEVOLA
ID:
Barriers and Facilitators to enrollment into the Community Retail Pharmacy Drug Distribution Point (CRPDDP) model and its treatment outcomes in a Peri-Urban Setting, A Case of Iganga Hospital
REFNo: HS3892ES

To explore the facilitators and barriers to enrollment into the CRPDDP model at Iganga Hospital in East Central Uganda.,To determine retention, viral load suppression, and associated factors among PLHIV enrolled in CRPDDP at Iganga Hospital in East Central Uganda.,To explore Barriers and Facilitators to enrollment into the Community Retail Pharmacy Drug Distribution Point (CRPDDP) model and its treatment outcomes in a Peri-Urban Setting.,
Uganda 2024-05-07 14:03:28 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacqueline Kyosiimire-Lugemwa
ID: UNCST-2022-R005393
AN In-vitro PROTOCOL TO ASSESS SAFETY and EFFICACY OF NATURAL/HERBAL INVESTIGATIONAL THERAPEUTIC PRODUCTS IN UGANDA
REFNo: HS4041ES

SPECIFIC OBJECTIVES:
1) To determine bacterial/ fungal sterility of the natural products
2) To determine the cytotoxicity of the natural products
3) To determine the in-vitro anti-virus activity of natural products
4) To determine the in-vitro anti-bacterial activity of the natural products.
5) To determine the in-vitro anti-fungal activity of the natural products.
6) To determine the in-vitro anti-diabetic activity of the natural products.
7) To determine the in-vitro anti-cancer activity of the natural products.
8) To determine the in-vitro anti-inflammatory/ antioxidant activity of the natural products.
9) To determine the in-vitro anti (condition/disease) activity of the natural products, whereby innovation might be addressing a condition or disease might be of relevancy in Uganda, e.g. conditions like alcohol overuse which causes liver damage, or a disease like malaria. This protocol takes care of other innovative solutions that will come up in future. Thus, the protocol is not limited to the above conditions only.
10) For successful products, to design experiments that will contribute to other mechanism identification (examples are to assess presence of ACE2 blockers (proteins that prevent the SARS COV2 from binding the ACE2 receptor)/ ACE2 Decoys.

Uganda 2024-05-07 14:00:29 2027-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nabbanja Teddy
ID:
A Model for eHealth Care Service Adoption for Mental Health Systems in Central Uganda. Case study: Butabika Referral Mental Hospital (BRMH)
REFNo: SIR305ES

Main Objective
The aim of this study is to develop a model for eHealth care service adoption that will enhance mental health service provision for health systems in Central Uganda.
Specific objectives
i) To examine the mental health care services provided by Butabika Hospital.
ii) To evaluate the existing mental health system for care services provision in Butabika Hospital.
iii) To design an e-Health Service Care Model for mental health service provision in Butabika Hospital.
iv) To validate the e-Health Service Care Model for mental health service provision in Butabika Hospital.

Uganda 2024-05-07 13:54:04 2027-05-07 Engineering and Technology Non-Clinical Trial Degree Award
Soumya Mishra
ID:
Examining PRC-associated Economic Development Zones in Africa: local impacts and the implications for host states
REFNo: SS2384ES

(1) What narratives and Sino-African interactions accompany the establishment of PRC-associated EDZs in Sub-Saharan Africa?(2) To what extent do PRC-associated EDZs meet their stated aims in terms of industrialisation, employment creation and other economic impacts? (3) What are the broader social, economic, political and environmental impacts of PRC-associated EDZs?
India 2024-05-07 13:52:47 2027-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
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